摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[(1-pyridin-2-ylpiperidin-3-yl)methyl]-2-(pyrimidin-2-ylthio)acetamide —— C17H21N5OS
    N-[(1-pyridin-2-ylpiperidin-3-yl)methyl]-2-(pyrimidin-2-ylthio)acetamide
    —— 2-[(3-ethyl-1H-1,2,4-triazol-5-yl)thio]-N-[1-methyl-3-(1H-pyrazol-1-yl)propyl]acetamide —— C13H20N6OS
    2-[(3-ethyl-1H-1,2,4-triazol-5-yl)thio]-N-[1-methyl-3-(1H-pyrazol-1-yl)propyl]acetamide
    —— N-[2-(2-amino-1,3-thiazol-4-yl)ethyl]-2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]acetamide —— C10H14N6OS2
    N-[2-(2-amino-1,3-thiazol-4-yl)ethyl]-2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]acetamide
    —— N-[2-(3-benzyl-1,2,4-oxadiazol-5-yl)ethyl]-2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]acetamide —— C16H18N6O2S
    N-[2-(3-benzyl-1,2,4-oxadiazol-5-yl)ethyl]-2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]acetamide
    —— N-methyl-2-[(2-methylphenyl)thio]-N-[(3-propyl-1,2,4-oxadiazol-5-yl)methyl]acetamide —— C16H21N3O2S
    N-methyl-2-[(2-methylphenyl)thio]-N-[(3-propyl-1,2,4-oxadiazol-5-yl)methyl]acetamide
    —— 1-(5-{[(4-methyl-4H-1,2,4-triazol-3-yl)thio]acetyl}-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)propan-1-ol —— C14H20N6O2S
    1-(5-{[(4-methyl-4H-1,2,4-triazol-3-yl)thio]acetyl}-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)propan-1-ol
    —— 2-[(5-methyl-1,3,4-oxadiazol-2-yl)thio]-N-[trans-4-(pyridin-2-yloxy)tetrahydro-2H-pyran-3-yl]acetamide —— C15H18N4O4S
    2-[(5-methyl-1,3,4-oxadiazol-2-yl)thio]-N-[trans-4-(pyridin-2-yloxy)tetrahydro-2H-pyran-3-yl]acetamide
    —— N-{[4-(dimethylamino)tetrahydro-2H-pyran-4-yl]methyl}-2-[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetamide —— C13H23N5O2S
    N-{[4-(dimethylamino)tetrahydro-2H-pyran-4-yl]methyl}-2-[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetamide
    —— 2-methyl-3-phenyl-N-[2-(1H-1,2,4-triazol-5-ylthio)ethyl]cycloprop-2-ene-1-carboxamide —— C15H16N4OS
    2-methyl-3-phenyl-N-[2-(1H-1,2,4-triazol-5-ylthio)ethyl]cycloprop-2-ene-1-carboxamide
    —— 2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]-N-(pyridin-2-ylmethyl)-N-(tetrahydrofuran-2-ylmethyl)acetamide —— C16H21N5O2S
    2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]-N-(pyridin-2-ylmethyl)-N-(tetrahydrofuran-2-ylmethyl)acetamide
    —— 2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-[3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)propyl]acetamide —— C11H17N7OS2
    2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-[3-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)propyl]acetamide
    —— ethyl (5E)-2-methyl-5-[(4-methylsulfanylphenyl)methylidene]-4-oxo-1H-pyrrole-3-carboxylate —— C16H17NO3S
    ethyl (5E)-2-methyl-5-[(4-methylsulfanylphenyl)methylidene]-4-oxo-1H-pyrrole-3-carboxylate
    —— N-[2-(2-isopropyl-1,3-thiazol-4-yl)ethyl]-2-(pyridin-4-ylthio)acetamide —— C15H19N3OS2
    N-[2-(2-isopropyl-1,3-thiazol-4-yl)ethyl]-2-(pyridin-4-ylthio)acetamide
    —— 4-(3-Aminocyclobutyl)-6-{4-[(4-methylphenyl)thio]piperidin-1-yl}pyrimidin-2-amine —— C20H27N5S
    4-(3-Aminocyclobutyl)-6-{4-[(4-methylphenyl)thio]piperidin-1-yl}pyrimidin-2-amine
    —— N-[(2-aminopyridin-3-yl)methyl]-2-[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetamide —— C11H14N6OS
    N-[(2-aminopyridin-3-yl)methyl]-2-[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetamide
    —— N-[(1S,5S,6S,7R)-7-cyclopentyl-2-oxabicyclo[3.2.0]heptan-6-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C16H24N4O2S
    N-[(1S,5S,6S,7R)-7-cyclopentyl-2-oxabicyclo[3.2.0]heptan-6-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-[2-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethyl]acetamide —— C13H17N5OS3
    2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-[2-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethyl]acetamide
    —— 6-(3-aminocyclobutyl)-N-{3-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]propyl}pyrimidin-4-amine —— C14H20N6S2
    6-(3-aminocyclobutyl)-N-{3-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]propyl}pyrimidin-4-amine
    —— 2-[[(5Z)-5-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl]benzonitrile —— C25H17N3O4S2
    2-[[(5Z)-5-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl]benzonitrile
    —— 2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-N-[2-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)ethyl]acetamide —— C14H14N6O2S2
    2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-N-[2-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)ethyl]acetamide
    —— N-methyl-2-(pyridin-4-ylthio)-N-(4,5,6,7-tetrahydro-1,2-benzisoxazol-3-ylmethyl)acetamide —— C16H19N3O2S
    N-methyl-2-(pyridin-4-ylthio)-N-(4,5,6,7-tetrahydro-1,2-benzisoxazol-3-ylmethyl)acetamide
    —— (1-methyl-1H-pyrazol-5-yl)(5-{[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetyl}-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)methanol —— C16H20N8O2S
    (1-methyl-1H-pyrazol-5-yl)(5-{[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetyl}-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)methanol
    —— N-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-ylmethyl)-3-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]propanamide —— C16H17N7O2S
    N-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-ylmethyl)-3-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]propanamide
    —— 2-(3-methylisoxazol-5-yl)-N-[2-(1H-1,2,3-triazol-5-ylthio)ethyl]acetamide —— C10H13N5O2S
    2-(3-methylisoxazol-5-yl)-N-[2-(1H-1,2,3-triazol-5-ylthio)ethyl]acetamide
    —— N-ethyl-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-2-pyridin-4-ylsulfanylacetamide —— C13H18N2O3S
    N-ethyl-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-2-pyridin-4-ylsulfanylacetamide
    —— N-{trans-3-[(3,5-dimethylisoxazol-4-yl)methoxy]tetrahydro-2H-pyran-4-yl}-2-[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetamide —— C16H23N5O4S
    N-{trans-3-[(3,5-dimethylisoxazol-4-yl)methoxy]tetrahydro-2H-pyran-4-yl}-2-[(3-methyl-1H-1,2,4-triazol-5-yl)thio]acetamide
    —— 1,2,5-trimethyl-N-[2-(1H-1,2,4-triazol-5-ylthio)ethyl]-1H-pyrrole-3-carboxamide —— C12H17N5OS
    1,2,5-trimethyl-N-[2-(1H-1,2,4-triazol-5-ylthio)ethyl]-1H-pyrrole-3-carboxamide
    —— 2-[2-(ethylthio)-1,3-thiazol-4-yl]-N-[trans-4-methoxytetrahydro-2H-pyran-3-yl]acetamide —— C13H20N2O3S2
    2-[2-(ethylthio)-1,3-thiazol-4-yl]-N-[trans-4-methoxytetrahydro-2H-pyran-3-yl]acetamide
    —— N-[(1S,5S,6S,7R)-7-cyclopentyl-2-oxabicyclo[3.2.0]heptan-6-yl]-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C16H24N4O2S
    N-[(1S,5S,6S,7R)-7-cyclopentyl-2-oxabicyclo[3.2.0]heptan-6-yl]-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— [(Z)-(1-phenyl-4-phenylsulfanylbutylidene)amino]urea —— C17H19N3OS
    [(Z)-(1-phenyl-4-phenylsulfanylbutylidene)amino]urea
    —— 2-[[5-[(2-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(Z)-1-(2-hydroxyphenyl)ethylideneamino]acetamide —— C19H17ClN4O2S3
    2-[[5-[(2-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(Z)-1-(2-hydroxyphenyl)ethylideneamino]acetamide
    —— N-{2-[(1-methyl-1H-imidazol-2-yl)thio]ethyl}-1,3,5-triazin-2-amine —— C9H12N6S
    N-{2-[(1-methyl-1H-imidazol-2-yl)thio]ethyl}-1,3,5-triazin-2-amine
    —— (5Z)-3-(4-bromo-3-chlorophenyl)-5-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one —— C23H14BrClN2O3S3
    (5Z)-3-(4-bromo-3-chlorophenyl)-5-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
    —— 2-[(4,6-dimethylpyrimidin-2-yl)thio]-N-(3-pyridin-4-ylpropyl)propanamide —— C17H22N4OS
    2-[(4,6-dimethylpyrimidin-2-yl)thio]-N-(3-pyridin-4-ylpropyl)propanamide
    —— (4E)-1-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-[hydroxy(phenyl)methylidene]-5-(thiophen-2-yl)pyrrolidine-2,3-dione —— C24H17N3O3S3
    (4E)-1-[5-(benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-4-[hydroxy(phenyl)methylidene]-5-(thiophen-2-yl)pyrrolidine-2,3-dione
    —— N-[(2-isopropyl-1,3-thiazol-4-yl)methyl]-2-(pyridin-2-ylthio)propanamide —— C15H19N3OS2
    N-[(2-isopropyl-1,3-thiazol-4-yl)methyl]-2-(pyridin-2-ylthio)propanamide
    —— 2-chloro-5-[(2Z)-2-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]hydrazinyl]benzoic acid —— C21H16ClN3O4S
    2-chloro-5-[(2Z)-2-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]hydrazinyl]benzoic acid
    —— N-[1-(1-methyl-1H-pyrazol-5-yl)propyl]-2-[(4-methyl-1,3-thiazol-2-yl)thio]acetamide —— C13H18N4OS2
    N-[1-(1-methyl-1H-pyrazol-5-yl)propyl]-2-[(4-methyl-1,3-thiazol-2-yl)thio]acetamide
    —— N-{[1-(1H-pyrazol-1-ylmethyl)cyclopropyl]methyl}-2-(pyridin-4-ylthio)acetamide —— C15H18N4OS
    N-{[1-(1H-pyrazol-1-ylmethyl)cyclopropyl]methyl}-2-(pyridin-4-ylthio)acetamide
    —— N-(1-benzyl-5-oxopyrrolidin-3-yl)-2-[(4-methyl-1,3-thiazol-2-yl)thio]acetamide —— C17H19N3O2S2
    N-(1-benzyl-5-oxopyrrolidin-3-yl)-2-[(4-methyl-1,3-thiazol-2-yl)thio]acetamide
    —— 2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-(1-pyrimidin-2-ylpiperidin-3-yl)acetamide —— C13H17N7OS2
    2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]-N-(1-pyrimidin-2-ylpiperidin-3-yl)acetamide
    —— N-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]-2-[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]propanamide —— C13H18N6O2S2
    N-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]-2-[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]propanamide
    —— N-[rac-(1S,5S,6R,7R)-7-cyclopentyl-2-oxabicyclo[3.2.0]hept-6-yl]-2-[(3-ethyl-1H-1,2,4-triazol-5-yl)thio]acetamide —— C17H26N4O2S
    N-[rac-(1S,5S,6R,7R)-7-cyclopentyl-2-oxabicyclo[3.2.0]hept-6-yl]-2-[(3-ethyl-1H-1,2,4-triazol-5-yl)thio]acetamide
    —— 2-(pyridin-4-ylthio)-N-[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]acetamide —— C17H25N3O2S
    2-(pyridin-4-ylthio)-N-[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]acetamide
    —— 3-(4-acetyl-3,5-dimethyl-1H-pyrazol-1-yl)-N-{2-[(1-methyl-1H-tetrazol-5-yl)thio]ethyl}propanamide —— C14H21N7O2S
    3-(4-acetyl-3,5-dimethyl-1H-pyrazol-1-yl)-N-{2-[(1-methyl-1H-tetrazol-5-yl)thio]ethyl}propanamide
    —— 2-(4-{[5-(Cyclohexylthio)-2-furyl]methyl}piperazin-1-yl)ethanol —— C17H28N2O2S
    2-(4-{[5-(Cyclohexylthio)-2-furyl]methyl}piperazin-1-yl)ethanol
    —— (1S,3R)-3-hydroxy-N-[(4-methylsulfanylphenyl)methyl]-N-propylcyclohexane-1-carboxamide —— C18H27NO2S
    (1S,3R)-3-hydroxy-N-[(4-methylsulfanylphenyl)methyl]-N-propylcyclohexane-1-carboxamide
    —— 1-(5-{[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]acetyl}-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)propan-1-ol —— C14H19N5O2S2
    1-(5-{[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]acetyl}-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)propan-1-ol
    —— 2-(pyridin-4-ylthio)-N-[(2-pyrimidin-2-yl-1,3-thiazol-4-yl)methyl]acetamide —— C15H13N5OS2
    2-(pyridin-4-ylthio)-N-[(2-pyrimidin-2-yl-1,3-thiazol-4-yl)methyl]acetamide
    —— 6-(cis-3-aminocyclobutyl)-2-(methoxymethyl)-N-{2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]ethyl}pyrimidin-4-amine —— C15H23N7OS
    6-(cis-3-aminocyclobutyl)-2-(methoxymethyl)-N-{2-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]ethyl}pyrimidin-4-amine