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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[(Z)-(4-fluorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C13H11FN4OS
    N-[(Z)-(4-fluorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— N-[(2R)-heptan-2-yl]-2-[(5-methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C15H26N4OS
    N-[(2R)-heptan-2-yl]-2-[(5-methyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— (2S)-2-phenylsulfanyl-N-[(Z)-pyridin-3-ylmethylideneamino]propanamide —— C15H15N3OS
    (2S)-2-phenylsulfanyl-N-[(Z)-pyridin-3-ylmethylideneamino]propanamide
    —— N-[(Z)-(3-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C13H11ClN4OS
    N-[(Z)-(3-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— N-[(Z)-(4-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C13H11ClN4OS
    N-[(Z)-(4-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— 2-pyrimidin-2-ylsulfanyl-N-[(Z)-(2,3,4-trimethylphenyl)methylideneamino]acetamide —— C16H18N4OS
    2-pyrimidin-2-ylsulfanyl-N-[(Z)-(2,3,4-trimethylphenyl)methylideneamino]acetamide
    —— (2S)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylpropanamide —— C14H13ClN4OS
    (2S)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylpropanamide
    —— N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C13H11ClN4OS
    N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— N-[(Z)-benzylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C13H12N4OS
    N-[(Z)-benzylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— (2R)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylpropanamide —— C14H13ClN4OS
    (2R)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylpropanamide
    —— (2R)-2-phenylsulfanyl-N-[(Z)-pyridin-3-ylmethylideneamino]propanamide —— C15H15N3OS
    (2R)-2-phenylsulfanyl-N-[(Z)-pyridin-3-ylmethylideneamino]propanamide
    —— (2S)-2-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylsulfanyl)propanoic acid —— C10H12N2O2S
    (2S)-2-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylsulfanyl)propanoic acid
    —— (2R)-2-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylsulfanyl)propanoic acid —— C10H12N2O2S
    (2R)-2-(6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylsulfanyl)propanoic acid
    —— (Z)-N-(3,5-dimethyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine —— C12H14N4S
    (Z)-N-(3,5-dimethyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine
    —— N-[[(2R)-4-(2-methylpropyl)morpholin-2-yl]methyl]-2-phenylsulfanylacetamide —— C17H26N2O2S
    N-[[(2R)-4-(2-methylpropyl)morpholin-2-yl]methyl]-2-phenylsulfanylacetamide
    —— 3-fluoro-N'-{[5-(2-pyridinylsulfanyl)-2-furyl]methylene}benzohydrazide —— C17H12FN3O2S
    3-fluoro-N'-{[5-(2-pyridinylsulfanyl)-2-furyl]methylene}benzohydrazide
    —— N-[(Z)-(3-methylphenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C14H14N4OS
    N-[(Z)-(3-methylphenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— N-[(Z)-pyridin-3-ylmethylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C12H11N5OS
    N-[(Z)-pyridin-3-ylmethylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— (5Z)-2-(4-methylphenyl)-5-[4-(methylsulfanyl)benzylidene]-1,3-thiazol-4(5H)-one —— C18H15NOS2
    (5Z)-2-(4-methylphenyl)-5-[4-(methylsulfanyl)benzylidene]-1,3-thiazol-4(5H)-one
    —— N-[(Z)-(3-fluorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C14H12FN3OS
    N-[(Z)-(3-fluorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— N-[(Z)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide —— C17H13N3O2S
    N-[(Z)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide
    —— N-[(Z)-pyridin-3-ylmethylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C13H12N4OS
    N-[(Z)-pyridin-3-ylmethylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— N-[(Z)-(4-chlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C14H12ClN3OS
    N-[(Z)-(4-chlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— N-[(Z)-furan-2-ylmethylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C12H11N3O2S
    N-[(Z)-furan-2-ylmethylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— 2-pyridin-2-ylsulfanyl-N-[(Z)-thiophen-2-ylmethylideneamino]acetamide —— C12H11N3OS2
    2-pyridin-2-ylsulfanyl-N-[(Z)-thiophen-2-ylmethylideneamino]acetamide
    —— N-[(Z)-pyridin-4-ylmethylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C13H12N4OS
    N-[(Z)-pyridin-4-ylmethylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-2-pyridin-2-ylsulfanylacetamide 326000-67-3 C16H18N4OS
    N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— N-[(Z)-(2-fluorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide —— C14H12FN3OS
    N-[(Z)-(2-fluorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
    —— (6E)-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one —— C18H17N3OS
    (6E)-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one
    —— (2S)-3-[ethyl-[2-(4-fluorophenyl)sulfanylethyl]amino]-2-methylpropanoic acid —— C14H20FNO2S
    (2S)-3-[ethyl-[2-(4-fluorophenyl)sulfanylethyl]amino]-2-methylpropanoic acid
    —— (2R)-3-[ethyl-[2-(4-fluorophenyl)sulfanylethyl]amino]-2-methylpropanoic acid —— C14H20FNO2S
    (2R)-3-[ethyl-[2-(4-fluorophenyl)sulfanylethyl]amino]-2-methylpropanoic acid
    —— 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-1-(4-methylphenyl)ethylideneamino]acetamide —— C17H20N4OS
    2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-1-(4-methylphenyl)ethylideneamino]acetamide
    —— 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(Z)-(4-methylphenyl)methylidene]acetohydrazide —— C16H18N4OS
    2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N'-[(Z)-(4-methylphenyl)methylidene]acetohydrazide
    —— (NZ)-N-[[5-[2-(diethylamino)ethyl]-2-ethylsulfanylthiophen-3-yl]methylidene]hydroxylamine —— C13H22N2OS2
    (NZ)-N-[[5-[2-(diethylamino)ethyl]-2-ethylsulfanylthiophen-3-yl]methylidene]hydroxylamine
    —— (2Z)-2-[1-(4-chloroanilino)ethylidene]-1-benzothiophen-3-one —— C16H12ClNOS
    (2Z)-2-[1-(4-chloroanilino)ethylidene]-1-benzothiophen-3-one
    —— 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-(4-ethylphenyl)methylideneamino]acetamide —— C17H20N4OS
    2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-(4-ethylphenyl)methylideneamino]acetamide
    —— N-[(Z)-benzylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamide —— C15H16N4OS
    N-[(Z)-benzylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamide
    —— (2Z)-2-(1-anilinoethylidene)-1-benzothiophen-3-one —— C16H13NOS
    (2Z)-2-(1-anilinoethylidene)-1-benzothiophen-3-one
    —— (2Z)-2-[1-(4-bromoanilino)ethylidene]-1-benzothiophen-3-one —— C16H12BrNOS
    (2Z)-2-[1-(4-bromoanilino)ethylidene]-1-benzothiophen-3-one
    —— (2Z)-2-[(4-bromoanilino)methylidene]-1-benzothiophen-3-one —— C15H10BrNOS
    (2Z)-2-[(4-bromoanilino)methylidene]-1-benzothiophen-3-one
    —— (2Z)-2-[1-(cyclohexylamino)ethylidene]-1-benzothiophen-3-one —— C16H19NOS
    (2Z)-2-[1-(cyclohexylamino)ethylidene]-1-benzothiophen-3-one
    —— (2R)-3-[ethyl-(2-pyridin-4-ylsulfanylacetyl)amino]-2-methylpropanoic acid —— C13H18N2O3S
    (2R)-3-[ethyl-(2-pyridin-4-ylsulfanylacetyl)amino]-2-methylpropanoic acid
    —— (2Z)-2-[(piperidin-1-ylamino)methylidene]-1-benzothiophen-3-one —— C14H16N2OS
    (2Z)-2-[(piperidin-1-ylamino)methylidene]-1-benzothiophen-3-one
    —— (2Z)-2-[1-(3-bromoanilino)ethylidene]-1-benzothiophen-3-one —— C16H12BrNOS
    (2Z)-2-[1-(3-bromoanilino)ethylidene]-1-benzothiophen-3-one
    —— 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-pyridin-2-ylmethylideneamino]acetamide —— C14H15N5OS
    2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-pyridin-2-ylmethylideneamino]acetamide
    —— (2Z)-2-[1-(2-bromoanilino)ethylidene]-1-benzothiophen-3-one —— C16H12BrNOS
    (2Z)-2-[1-(2-bromoanilino)ethylidene]-1-benzothiophen-3-one
    —— 2-[(4,6-dimethylpyrimidin-2-yl)thio]-N'-[(1E)-1-thien-2-ylethylidene]acetohydrazide —— C14H16N4OS2
    2-[(4,6-dimethylpyrimidin-2-yl)thio]-N'-[(1E)-1-thien-2-ylethylidene]acetohydrazide
    —— (2S)-3-[ethyl-(2-pyridin-4-ylsulfanylacetyl)amino]-2-methylpropanoic acid —— C13H18N2O3S
    (2S)-3-[ethyl-(2-pyridin-4-ylsulfanylacetyl)amino]-2-methylpropanoic acid
    —— (2R)-2-phenylsulfanyl-N-[(Z)-pyridin-4-ylmethylideneamino]propanamide —— C15H15N3OS
    (2R)-2-phenylsulfanyl-N-[(Z)-pyridin-4-ylmethylideneamino]propanamide
    —— N-[(Z)-(2-chloro-6-fluorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C13H10ClFN4OS
    N-[(Z)-(2-chloro-6-fluorophenyl)methylideneamino]-2-pyrimidin-2-ylsulfanylacetamide