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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (1R,2S)-1-(3-chlorophenyl)-1-thiophen-2-ylsulfanylbutan-2-amine —— C14H16ClNS2
    (1R,2S)-1-(3-chlorophenyl)-1-thiophen-2-ylsulfanylbutan-2-amine
    —— (1S,2S)-1-(3-chlorophenyl)-1-(1,3,4-thiadiazol-2-ylsulfanyl)butan-2-amine —— C12H14ClN3S2
    (1S,2S)-1-(3-chlorophenyl)-1-(1,3,4-thiadiazol-2-ylsulfanyl)butan-2-amine
    —— (2S)-2-(3-chlorophenyl)-2-phenylsulfanylethanamine —— C14H14ClNS
    (2S)-2-(3-chlorophenyl)-2-phenylsulfanylethanamine
    —— (1S,2R)-1-(3-chlorophenyl)-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine —— C13H17ClN4S
    (1S,2R)-1-(3-chlorophenyl)-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine
    —— (2R)-2-(3-chlorophenyl)-2-(2,4-dimethylphenyl)sulfanylethanamine —— C16H18ClNS
    (2R)-2-(3-chlorophenyl)-2-(2,4-dimethylphenyl)sulfanylethanamine
    —— (2S)-2-(3-chlorophenyl)-2-(3,4-dimethylphenyl)sulfanylethanamine —— C16H18ClNS
    (2S)-2-(3-chlorophenyl)-2-(3,4-dimethylphenyl)sulfanylethanamine
    —— (2S)-2-(3-chlorophenyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine —— C11H13ClN4S
    (2S)-2-(3-chlorophenyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanamine
    —— 2-[1-(2,4-dimethylanilino)ethylidene]-1-benzothiophen-3-one —— C18H17NOS
    2-[1-(2,4-dimethylanilino)ethylidene]-1-benzothiophen-3-one
    —— (1R,2R)-1-(3-chlorophenyl)-1-pyridin-2-ylsulfanylbutan-2-amine —— C15H17ClN2S
    (1R,2R)-1-(3-chlorophenyl)-1-pyridin-2-ylsulfanylbutan-2-amine
    —— N-[(3-Bromophenyl)methyl]-4-{6,8-dimethyl-2-oxo-1H,2H,3H-pyrido[2,3-B][1,4]thiazin-1-YL}butanamide —— C20H22BrN3O2S
    N-[(3-Bromophenyl)methyl]-4-{6,8-dimethyl-2-oxo-1H,2H,3H-pyrido[2,3-B][1,4]thiazin-1-YL}butanamide
    —— 2-Methyl-7-{[(4-methylphenyl)sulfanyl]methyl}-5H-[1,3,4]thiadiazolo[3,2-A]pyrimidin-5-one —— C14H13N3OS2
    2-Methyl-7-{[(4-methylphenyl)sulfanyl]methyl}-5H-[1,3,4]thiadiazolo[3,2-A]pyrimidin-5-one
    —— (1S,2S)-1-(3-chlorophenyl)-1-phenylsulfanylbutan-2-amine —— C16H18ClNS
    (1S,2S)-1-(3-chlorophenyl)-1-phenylsulfanylbutan-2-amine
    —— (1S,2R)-1-(3-chlorophenyl)-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine —— C14H18ClN3S
    (1S,2R)-1-(3-chlorophenyl)-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine
    —— (2R)-N-(6-amino-1-benzyl-2,4-dioxopyrimidin-5-yl)-N-methyl-2-phenylsulfanylpropanamide —— C21H22N4O3S
    (2R)-N-(6-amino-1-benzyl-2,4-dioxopyrimidin-5-yl)-N-methyl-2-phenylsulfanylpropanamide
    —— (2R)-N-cyclopentyl-3-methyl-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]butanamide —— C15H26N4O2S
    (2R)-N-cyclopentyl-3-methyl-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]butanamide
    —— 2-(2-bromophenyl)-5-(2-methylsulfonylethylsulfanyl)-1,3,4-oxadiazole —— C11H11BrN2O3S2
    2-(2-bromophenyl)-5-(2-methylsulfonylethylsulfanyl)-1,3,4-oxadiazole
    —— N-methyl-4-(2-oxopyrido[2,3-b][1,4]thiazin-1-yl)butanamide —— C12H15N3O2S
    N-methyl-4-(2-oxopyrido[2,3-b][1,4]thiazin-1-yl)butanamide
    —— (2S)-2-(3-fluorophenyl)-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]ethanamine —— C11H13FN4S
    (2S)-2-(3-fluorophenyl)-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]ethanamine
    —— (2S)-2-(2,5-difluorophenyl)sulfanyl-2-(3-fluorophenyl)ethanamine —— C14H12F3NS
    (2S)-2-(2,5-difluorophenyl)sulfanyl-2-(3-fluorophenyl)ethanamine
    —— (1S,2R)-1-(3-fluorophenyl)-1-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine —— C13H17FN4S
    (1S,2R)-1-(3-fluorophenyl)-1-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine
    —— (1S,2S)-1-(3-fluorophenyl)-1-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine —— C13H17FN4S
    (1S,2S)-1-(3-fluorophenyl)-1-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine
    —— 6-amino-2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-1H-pyrimidin-4-one —— C12H13FN4OS
    6-amino-2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-1H-pyrimidin-4-one
    —— (2R)-2-(3-fluorophenyl)-2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine —— C10H11FN4S
    (2R)-2-(3-fluorophenyl)-2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine
    —— (1R,2S)-1-(3-fluorophenyl)-1-(1-methyltetrazol-5-yl)sulfanylbutan-2-amine —— C12H16FN5S
    (1R,2S)-1-(3-fluorophenyl)-1-(1-methyltetrazol-5-yl)sulfanylbutan-2-amine
    —— (1R,2R)-1-(3-fluorophenyl)-1-(1H-1,2,4-triazol-5-ylsulfanyl)butan-2-amine —— C12H15FN4S
    (1R,2R)-1-(3-fluorophenyl)-1-(1H-1,2,4-triazol-5-ylsulfanyl)butan-2-amine
    —— 2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanylpyrimidine-4,6-diamine —— C12H14FN5S
    2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanylpyrimidine-4,6-diamine
    —— (2R)-2-(3-fluorophenyl)-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]ethanamine —— C11H13FN4S
    (2R)-2-(3-fluorophenyl)-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]ethanamine
    —— (1S,2R)-1-(3-fluorophenyl)-1-(1H-1,2,4-triazol-5-ylsulfanyl)butan-2-amine —— C12H15FN4S
    (1S,2R)-1-(3-fluorophenyl)-1-(1H-1,2,4-triazol-5-ylsulfanyl)butan-2-amine
    —— (1S,2R)-1-(3-fluorophenyl)-1-pyrimidin-2-ylsulfanylbutan-2-amine —— C14H16FN3S
    (1S,2R)-1-(3-fluorophenyl)-1-pyrimidin-2-ylsulfanylbutan-2-amine
    —— 2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-1H-pyrimidin-6-one —— C12H12FN3OS
    2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-1H-pyrimidin-6-one
    —— (2S)-2-(3,4-difluorophenyl)sulfanyl-2-(3-fluorophenyl)ethanamine —— C14H12F3NS
    (2S)-2-(3,4-difluorophenyl)sulfanyl-2-(3-fluorophenyl)ethanamine
    —— (2R)-2-(3-fluorophenyl)-2-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]ethanamine —— C12H13FN2S2
    (2R)-2-(3-fluorophenyl)-2-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]ethanamine
    —— (1R,2R)-1-(3-fluorophenyl)-1-thiophen-2-ylsulfanylbutan-2-amine —— C14H16FNS2
    (1R,2R)-1-(3-fluorophenyl)-1-thiophen-2-ylsulfanylbutan-2-amine
    —— (1R,2R)-1-(3-fluorophenyl)-1-(1,3-thiazol-2-ylsulfanyl)butan-2-amine —— C13H15FN2S2
    (1R,2R)-1-(3-fluorophenyl)-1-(1,3-thiazol-2-ylsulfanyl)butan-2-amine
    —— (2R)-2-(3-fluorophenyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanamine —— C11H12FN3S2
    (2R)-2-(3-fluorophenyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanamine
    —— (1S,2S)-1-(3-fluorophenyl)-1-pyrimidin-2-ylsulfanylbutan-2-amine —— C14H16FN3S
    (1S,2S)-1-(3-fluorophenyl)-1-pyrimidin-2-ylsulfanylbutan-2-amine
    —— (2S)-2-(3-fluorophenyl)-2-(5-methylpyrimidin-2-yl)sulfanylethanamine —— C13H14FN3S
    (2S)-2-(3-fluorophenyl)-2-(5-methylpyrimidin-2-yl)sulfanylethanamine
    —— (1S,2S)-1-(3-fluorophenyl)-1-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]butan-2-amine —— C13H16FN3S2
    (1S,2S)-1-(3-fluorophenyl)-1-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]butan-2-amine
    —— 2-[(1R)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-1H-pyrimidin-6-one —— C12H12FN3OS
    2-[(1R)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-1H-pyrimidin-6-one
    —— (2S)-2-(3-fluorophenyl)-2-phenylsulfanylethanamine —— C14H14FNS
    (2S)-2-(3-fluorophenyl)-2-phenylsulfanylethanamine
    —— (1R,2S)-1-(3-fluorophenyl)-1-(1-methylpyrazol-4-yl)sulfanylbutan-2-amine —— C14H18FN3S
    (1R,2S)-1-(3-fluorophenyl)-1-(1-methylpyrazol-4-yl)sulfanylbutan-2-amine
    —— 5-[(5-Amino-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-2-methyl-[1,2]oxazolo[2,3-a]pyrimidin-7-one —— C10H9N5O2S2
    5-[(5-Amino-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-2-methyl-[1,2]oxazolo[2,3-a]pyrimidin-7-one
    —— (1S,2S)-1-(3-fluorophenyl)-1-phenylsulfanylbutan-2-amine —— C16H18FNS
    (1S,2S)-1-(3-fluorophenyl)-1-phenylsulfanylbutan-2-amine
    —— (1S,2S)-1-(3-fluorophenyl)-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine —— C14H18FN3S
    (1S,2S)-1-(3-fluorophenyl)-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine
    —— (2S)-2-(3-fluorophenyl)-2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine —— C10H11FN4S
    (2S)-2-(3-fluorophenyl)-2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine
    —— 2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-6-methyl-1H-pyrimidin-4-one —— C13H14FN3OS
    2-[(1S)-2-amino-1-(3-fluorophenyl)ethyl]sulfanyl-6-methyl-1H-pyrimidin-4-one
    —— (2R)-2-(2,4-dimethylphenyl)sulfanyl-2-(3-fluorophenyl)ethanamine —— C16H18FNS
    (2R)-2-(2,4-dimethylphenyl)sulfanyl-2-(3-fluorophenyl)ethanamine
    —— (1S,2R)-1-(3-fluorophenyl)-1-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]butan-2-amine —— C14H17FN2S2
    (1S,2R)-1-(3-fluorophenyl)-1-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]butan-2-amine
    —— (2S)-2-(2,4-dimethylphenyl)sulfanyl-2-(3-fluorophenyl)ethanamine —— C16H18FNS
    (2S)-2-(2,4-dimethylphenyl)sulfanyl-2-(3-fluorophenyl)ethanamine
    —— 5-((3-fluorobenzyl)thio)-7-(4-fluorophenyl)-1,3-dimethylpyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione —— C21H16F2N4O2S
    5-((3-fluorobenzyl)thio)-7-(4-fluorophenyl)-1,3-dimethylpyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione