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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2R)-2-(2,5-dimethylpyrazol-3-yl)sulfanyl-2-(4-fluorophenyl)ethanamine —— C13H16FN3S
    (2R)-2-(2,5-dimethylpyrazol-3-yl)sulfanyl-2-(4-fluorophenyl)ethanamine
    —— (2S)-2-(2,5-dimethylpyrazol-3-yl)sulfanylbutanoic acid —— C9H14N2O2S
    (2S)-2-(2,5-dimethylpyrazol-3-yl)sulfanylbutanoic acid
    —— (1R,2S)-1-(2,5-dimethylpyrazol-3-yl)sulfanyl-1-thiophen-2-ylbutan-2-amine —— C13H19N3S2
    (1R,2S)-1-(2,5-dimethylpyrazol-3-yl)sulfanyl-1-thiophen-2-ylbutan-2-amine
    —— (1S)-1-(4-aminophenyl)-2-(2,5-dimethylpyrazol-3-yl)sulfanylethanol —— C13H17N3OS
    (1S)-1-(4-aminophenyl)-2-(2,5-dimethylpyrazol-3-yl)sulfanylethanol
    —— 4-(2,5-dimethylpyrazol-3-yl)sulfanyl-N'-hydroxy-3-methylbenzenecarboximidamide —— C13H16N4OS
    4-(2,5-dimethylpyrazol-3-yl)sulfanyl-N'-hydroxy-3-methylbenzenecarboximidamide
    —— (1S,2S)-1-(2,5-dimethylpyrazol-3-yl)sulfanyl-1-(furan-2-yl)butan-2-amine —— C13H19N3OS
    (1S,2S)-1-(2,5-dimethylpyrazol-3-yl)sulfanyl-1-(furan-2-yl)butan-2-amine
    —— 2-(2,5-dimethylpyrazol-3-yl)sulfanyl-N-[(3R)-2-methyl-4-oxopentan-3-yl]acetamide —— C13H21N3O2S
    2-(2,5-dimethylpyrazol-3-yl)sulfanyl-N-[(3R)-2-methyl-4-oxopentan-3-yl]acetamide
    —— (2R)-2-amino-3-(2,5-dimethylpyrazol-3-yl)sulfanylpropanenitrile —— C8H12N4S
    (2R)-2-amino-3-(2,5-dimethylpyrazol-3-yl)sulfanylpropanenitrile
    —— (1S,2R,4R)-2-(2,5-dimethylpyrazol-3-yl)sulfanyl-4-ethylcyclohexane-1-carbonitrile —— C14H21N3S
    (1S,2R,4R)-2-(2,5-dimethylpyrazol-3-yl)sulfanyl-4-ethylcyclohexane-1-carbonitrile
    —— [(1S,2S)-2-(2,5-dimethylpyrazol-3-yl)sulfanylcyclohexyl]methanamine —— C12H21N3S
    [(1S,2S)-2-(2,5-dimethylpyrazol-3-yl)sulfanylcyclohexyl]methanamine
    —— (1R,2R)-1-(5-bromothiophen-2-yl)-1-(2,5-dimethylpyrazol-3-yl)sulfanylbutan-2-amine —— C13H18BrN3S2
    (1R,2R)-1-(5-bromothiophen-2-yl)-1-(2,5-dimethylpyrazol-3-yl)sulfanylbutan-2-amine
    —— (1S,2S)-1-(2,5-dimethylpyrazol-3-yl)sulfanyl-1-thiophen-2-ylbutan-2-amine —— C13H19N3S2
    (1S,2S)-1-(2,5-dimethylpyrazol-3-yl)sulfanyl-1-thiophen-2-ylbutan-2-amine
    —— (1R,2R)-2-methyl-N-(2-methylsulfonylethyl)cyclopropan-1-amine —— C7H15NO2S
    (1R,2R)-2-methyl-N-(2-methylsulfonylethyl)cyclopropan-1-amine
    —— N,N-Dimethyl-2-[6-methyl-3-[(phenylmethyl)thio]-1,2,4-triazin-5-yl]ethenamine 860787-89-9 C15H18N4S
    N,N-Dimethyl-2-[6-methyl-3-[(phenylmethyl)thio]-1,2,4-triazin-5-yl]ethenamine
    —— ethyl (2S)-2-[(R)-hydroxy-(4-methylsulfanylphenyl)methyl]butanoate —— C14H20O3S
    ethyl (2S)-2-[(R)-hydroxy-(4-methylsulfanylphenyl)methyl]butanoate
    —— methyl (2R)-2-[(R)-hydroxy-(4-methylsulfanylphenyl)methyl]-3-methylbutanoate —— C14H20O3S
    methyl (2R)-2-[(R)-hydroxy-(4-methylsulfanylphenyl)methyl]-3-methylbutanoate
    —— methyl (2S)-2-[(S)-hydroxy-(4-methylsulfanylphenyl)methyl]-3-methylbutanoate —— C14H20O3S
    methyl (2S)-2-[(S)-hydroxy-(4-methylsulfanylphenyl)methyl]-3-methylbutanoate
    —— ethyl (3S)-3-hydroxy-3-(4-methylsulfanylphenyl)butanoate —— C13H18O3S
    ethyl (3S)-3-hydroxy-3-(4-methylsulfanylphenyl)butanoate
    —— N-[2-[(2R)-1-methylpiperidin-2-yl]ethyl]-4-methylsulfanylaniline —— C15H24N2S
    N-[2-[(2R)-1-methylpiperidin-2-yl]ethyl]-4-methylsulfanylaniline
    —— N-[2-[(2S)-1-methylpiperidin-2-yl]ethyl]-4-methylsulfanylaniline —— C15H24N2S
    N-[2-[(2S)-1-methylpiperidin-2-yl]ethyl]-4-methylsulfanylaniline
    —— (1R)-1-(4-methylsulfanylphenyl)-N-(oxan-4-ylmethyl)ethanamine —— C15H23NOS
    (1R)-1-(4-methylsulfanylphenyl)-N-(oxan-4-ylmethyl)ethanamine
    —— 2-[(2R)-but-3-en-2-yl]sulfanylethanamine —— C6H13NS
    2-[(2R)-but-3-en-2-yl]sulfanylethanamine
    —— 2-[(2S)-but-3-en-2-yl]sulfanylethanamine —— C6H13NS
    2-[(2S)-but-3-en-2-yl]sulfanylethanamine
    —— 6-[(2R)-but-3-en-2-yl]sulfanylpyridin-3-amine —— C9H12N2S
    6-[(2R)-but-3-en-2-yl]sulfanylpyridin-3-amine
    —— 5-[(2R)-but-3-en-2-yl]sulfanyl-4-methyl-1,2,4-triazol-3-amine —— C7H12N4S
    5-[(2R)-but-3-en-2-yl]sulfanyl-4-methyl-1,2,4-triazol-3-amine
    —— 2-[(2R)-but-3-en-2-yl]sulfanylaniline —— C10H13NS
    2-[(2R)-but-3-en-2-yl]sulfanylaniline
    —— 5-[(2R)-but-3-en-2-yl]sulfanylpyridin-2-amine —— C9H12N2S
    5-[(2R)-but-3-en-2-yl]sulfanylpyridin-2-amine
    —— 4-[(2S)-but-3-en-2-yl]sulfanyl-3-fluoroaniline —— C10H12FNS
    4-[(2S)-but-3-en-2-yl]sulfanyl-3-fluoroaniline
    —— 2-[(2R)-but-3-en-2-yl]sulfanyl-5-fluoroaniline —— C10H12FNS
    2-[(2R)-but-3-en-2-yl]sulfanyl-5-fluoroaniline
    —— 5-[(2S)-but-3-en-2-yl]sulfanylpyridin-2-amine —— C9H12N2S
    5-[(2S)-but-3-en-2-yl]sulfanylpyridin-2-amine
    —— (1R,2R)-2-methyl-2-(4-methylsulfanylphenyl)cyclopropane-1-carboxylic acid —— C12H14O2S
    (1R,2R)-2-methyl-2-(4-methylsulfanylphenyl)cyclopropane-1-carboxylic acid
    —— (1S,2S)-2-methyl-2-(4-methylsulfanylphenyl)cyclopropane-1-carboxylic acid —— C12H14O2S
    (1S,2S)-2-methyl-2-(4-methylsulfanylphenyl)cyclopropane-1-carboxylic acid
    —— (1R,2R)-2-methyl-2-(4-methylsulfanylphenyl)cyclopropan-1-amine —— C11H15NS
    (1R,2R)-2-methyl-2-(4-methylsulfanylphenyl)cyclopropan-1-amine
    —— (2R)-1-(2,5-dimethylphenyl)sulfanyl-2-phenylpropan-2-ol —— C17H20OS
    (2R)-1-(2,5-dimethylphenyl)sulfanyl-2-phenylpropan-2-ol
    —— (2R)-1-(2-amino-4-fluorophenyl)sulfanyl-2-phenylpropan-2-ol —— C15H16FNOS
    (2R)-1-(2-amino-4-fluorophenyl)sulfanyl-2-phenylpropan-2-ol
    —— (2R)-1-(2-bromophenyl)sulfanyl-2-phenylpropan-2-ol —— C15H15BrOS
    (2R)-1-(2-bromophenyl)sulfanyl-2-phenylpropan-2-ol
    —— 6-amino-2-[(2R)-2-hydroxy-2-phenylpropyl]sulfanyl-1H-pyrimidin-4-one —— C13H15N3O2S
    6-amino-2-[(2R)-2-hydroxy-2-phenylpropyl]sulfanyl-1H-pyrimidin-4-one
    —— (2S)-1-[(5-amino-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-2-phenylpropan-2-ol —— C12H16N4OS
    (2S)-1-[(5-amino-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-2-phenylpropan-2-ol
    —— (2S)-1-(2,5-dimethylphenyl)sulfanyl-2-phenylpropan-2-ol —— C17H20OS
    (2S)-1-(2,5-dimethylphenyl)sulfanyl-2-phenylpropan-2-ol
    —— 2,4-dibromo-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one —— C18H15Br2N3OS
    2,4-dibromo-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one
    —— 4-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]-5-methyl-2-phenylpyrazol-3-one —— C22H21N5OS
    4-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]-5-methyl-2-phenylpyrazol-3-one
    —— 2-bromo-4-chloro-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one —— C18H15BrClN3OS
    2-bromo-4-chloro-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one
    —— 1-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]naphthalen-2-one —— C22H19N3OS
    1-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]naphthalen-2-one
    —— 6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]-2-nitrocyclohexa-2,4-dien-1-one —— C18H16N4O3S
    6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]-2-nitrocyclohexa-2,4-dien-1-one
    —— 4-bromo-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one —— C18H16BrN3OS
    4-bromo-6-[[2-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one
    —— (2S)-1-(4-ethylpiperazin-1-yl)-2-[[4-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-1-one —— C13H20F3N5OS
    (2S)-1-(4-ethylpiperazin-1-yl)-2-[[4-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]sulfanyl]propan-1-one
    —— N-[(1S)-3-methyl-1-phenylbutyl]-2-[[4-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C17H21F3N4OS
    N-[(1S)-3-methyl-1-phenylbutyl]-2-[[4-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 4-methyl-5-[2-[(3S)-piperidin-3-yl]ethylsulfanyl]-1,2,4-triazol-3-amine —— C10H19N5S
    4-methyl-5-[2-[(3S)-piperidin-3-yl]ethylsulfanyl]-1,2,4-triazol-3-amine
    —— (3R)-3-[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]piperidine —— C10H18N4S
    (3R)-3-[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]piperidine
    —— (3S)-3-[2-(2,4-dimethylphenyl)sulfanylethyl]piperidine —— C15H23NS
    (3S)-3-[2-(2,4-dimethylphenyl)sulfanylethyl]piperidine