摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (5E)-3-ethyl-5-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one —— C19H16N2O3S3
    (5E)-3-ethyl-5-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
    —— 3-bromo-N-[(Z)-[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylideneamino]benzamide —— C21H16BrN3O3S
    3-bromo-N-[(Z)-[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylideneamino]benzamide
    —— 2-[[5-[(2-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(Z)-1-thiophen-2-ylethylideneamino]acetamide —— C17H15ClN4OS4
    2-[[5-[(2-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(Z)-1-thiophen-2-ylethylideneamino]acetamide
    —— 4-[4-cyclopropyl-5-[(1R)-1-(5-phenyl-1,3,4-oxadiazol-2-yl)ethyl]sulfanyl-1,2,4-triazol-3-yl]morpholine —— C19H22N6O2S
    4-[4-cyclopropyl-5-[(1R)-1-(5-phenyl-1,3,4-oxadiazol-2-yl)ethyl]sulfanyl-1,2,4-triazol-3-yl]morpholine
    —— 1-[4-[(3R)-3-methylpiperidin-1-yl]sulfonyl-2-nitrophenyl]sulfanyl-3H-[1,2,4]triazolo[4,3-a]benzimidazole —— C20H20N6O4S2
    1-[4-[(3R)-3-methylpiperidin-1-yl]sulfonyl-2-nitrophenyl]sulfanyl-3H-[1,2,4]triazolo[4,3-a]benzimidazole
    —— 2-[(1R)-1-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]ethyl]-5-phenyl-1,3,4-oxadiazole —— C18H21N5OS
    2-[(1R)-1-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]ethyl]-5-phenyl-1,3,4-oxadiazole
    —— 4-[2-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-2-oxoethyl]sulfanyl-2,6-dimethylpyrimidine-5-carbonitrile —— C15H20N4O2S
    4-[2-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-2-oxoethyl]sulfanyl-2,6-dimethylpyrimidine-5-carbonitrile
    —— 4-[2-[(3R)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-2,6-dimethylpyrimidine-5-carbonitrile —— C22H18ClN5O2S
    4-[2-[(3R)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-2,6-dimethylpyrimidine-5-carbonitrile
    —— 4-[2-[(3S)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-2,6-dimethylpyrimidine-5-carbonitrile —— C22H18ClN5O2S
    4-[2-[(3S)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-2,6-dimethylpyrimidine-5-carbonitrile
    —— 2-(5-cyano-2,6-dimethylpyrimidin-4-yl)sulfanyl-N-[(1R)-3-methyl-1-phenylbutyl]acetamide —— C20H24N4OS
    2-(5-cyano-2,6-dimethylpyrimidin-4-yl)sulfanyl-N-[(1R)-3-methyl-1-phenylbutyl]acetamide
    —— (2R)-2-[[5-[acetyl(cyclopropyl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylpropanamide —— C15H22N4O4S3
    (2R)-2-[[5-[acetyl(cyclopropyl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylpropanamide
    —— N-[(6R)-6-methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-2-phenylsulfanylpyridine-3-carboxamide —— C20H19N3OS2
    N-[(6R)-6-methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]-2-phenylsulfanylpyridine-3-carboxamide
    —— N-cyclopropyl-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[(5-ethyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H20N4O3S2
    N-cyclopropyl-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[(5-ethyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— (5E)-5-[[5-(4-chlorophenyl)sulfanylfuran-2-yl]methylidene]-3-propyl-2-sulfanylidene-1,3-thiazolidin-4-one —— C17H14ClNO2S3
    (5E)-5-[[5-(4-chlorophenyl)sulfanylfuran-2-yl]methylidene]-3-propyl-2-sulfanylidene-1,3-thiazolidin-4-one
    —— (2S)-2-[[5-[acetyl(cyclopropyl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(3R)-1,1-dioxothiolan-3-yl]-N-methylpropanamide —— C15H22N4O4S3
    (2S)-2-[[5-[acetyl(cyclopropyl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(3R)-1,1-dioxothiolan-3-yl]-N-methylpropanamide
    —— 2-naphthalen-1-yl-N-[(Z)-[5-(4-oxo-3-phenylquinazolin-2-yl)sulfanylfuran-2-yl]methylideneamino]acetamide —— C31H22N4O3S
    2-naphthalen-1-yl-N-[(Z)-[5-(4-oxo-3-phenylquinazolin-2-yl)sulfanylfuran-2-yl]methylideneamino]acetamide
    —— N'-[(E)-1-(4-aminophenyl)ethylidene]-2-[(4,6-dimethyl-2-pyrimidinyl)thio]acetohydrazide —— C16H19N5OS
    N'-[(E)-1-(4-aminophenyl)ethylidene]-2-[(4,6-dimethyl-2-pyrimidinyl)thio]acetohydrazide
    —— 1,7-dicyclopropyl-5-[[(2S)-oxolan-2-yl]methylsulfanyl]pyrimido[4,5-d]pyrimidine-2,4-dione —— C17H20N4O3S
    1,7-dicyclopropyl-5-[[(2S)-oxolan-2-yl]methylsulfanyl]pyrimido[4,5-d]pyrimidine-2,4-dione
    —— N-[(Z)-(4-bromophenyl)methylideneamino]-2-(2-ethylsulfanyl-6-methylpyrimidin-4-yl)oxyacetamide —— C16H17BrN4O2S
    N-[(Z)-(4-bromophenyl)methylideneamino]-2-(2-ethylsulfanyl-6-methylpyrimidin-4-yl)oxyacetamide
    —— (Z)-N-(3-methylsulfanyl-[1,2,4]triazolo[4,3-b][1,2,4]triazol-7-yl)-1-pyridin-3-ylmethanimine —— C10H9N7S
    (Z)-N-(3-methylsulfanyl-[1,2,4]triazolo[4,3-b][1,2,4]triazol-7-yl)-1-pyridin-3-ylmethanimine
    —— (2S)-2-(1,7-dicyclopropyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanyl-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylpropanamide —— C20H25N5O5S2
    (2S)-2-(1,7-dicyclopropyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanyl-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylpropanamide
    —— 5-[(1R)-1-(2-chlorophenyl)ethyl]sulfanyl-1,7-dicyclopropylpyrimido[4,5-d]pyrimidine-2,4-dione —— C20H19ClN4O2S
    5-[(1R)-1-(2-chlorophenyl)ethyl]sulfanyl-1,7-dicyclopropylpyrimido[4,5-d]pyrimidine-2,4-dione
    —— (2S)-2-(1,7-dicyclopropyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanyl-N-[(4-fluorophenyl)methyl]propanamide —— C22H22FN5O3S
    (2S)-2-(1,7-dicyclopropyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanyl-N-[(4-fluorophenyl)methyl]propanamide
    —— (2R)-2-(1,7-dicyclopropyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanyl-N-[(4-fluorophenyl)methyl]propanamide —— C22H22FN5O3S
    (2R)-2-(1,7-dicyclopropyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanyl-N-[(4-fluorophenyl)methyl]propanamide
    —— (2S)-2-[[4-(2-amino-2-oxoethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-cyclopropylpropanamide —— C14H17N5O2S2
    (2S)-2-[[4-(2-amino-2-oxoethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-cyclopropylpropanamide
    —— 5-cyclopentyl-3-[[(1R)-2,2-dichlorocyclopropyl]methylsulfanyl]-1H-1,2,4-triazole —— C11H15Cl2N3S
    5-cyclopentyl-3-[[(1R)-2,2-dichlorocyclopropyl]methylsulfanyl]-1H-1,2,4-triazole
    —— [(2R)-2,3-dihydro-1-benzothiophen-2-yl]-(2-propan-2-yliminopyridin-1-yl)methanone —— C17H18N2OS
    [(2R)-2,3-dihydro-1-benzothiophen-2-yl]-(2-propan-2-yliminopyridin-1-yl)methanone
    —— 5-acetyl-6-methyl-2-[[(2R)-oxolan-2-yl]methylsulfanyl]pyridine-3-carbonitrile —— C14H16N2O2S
    5-acetyl-6-methyl-2-[[(2R)-oxolan-2-yl]methylsulfanyl]pyridine-3-carbonitrile
    —— 5-[(E)-2-(5-methylfuran-2-yl)ethenyl]-3-[(1R)-1-phenylethyl]sulfanyl-1H-1,2,4-triazole —— C17H17N3OS
    5-[(E)-2-(5-methylfuran-2-yl)ethenyl]-3-[(1R)-1-phenylethyl]sulfanyl-1H-1,2,4-triazole
    —— 3-[(1R)-1-(2-chlorophenyl)ethyl]sulfanyl-5-[(E)-2-(5-methylfuran-2-yl)ethenyl]-1H-1,2,4-triazole —— C17H16ClN3OS
    3-[(1R)-1-(2-chlorophenyl)ethyl]sulfanyl-5-[(E)-2-(5-methylfuran-2-yl)ethenyl]-1H-1,2,4-triazole
    —— (2R)-2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(3-fluorophenyl)methyl]-N-methylpropanamide —— C21H28FN5OS
    (2R)-2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(3-fluorophenyl)methyl]-N-methylpropanamide
    —— 2-[(1S)-1-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-5-(3-methylphenyl)-1,3,4-oxadiazole —— C21H26N6OS
    2-[(1S)-1-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-5-(3-methylphenyl)-1,3,4-oxadiazole
    —— 2-(4-fluorophenyl)-4-[[4-[[(2S)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-thiazole —— C22H26FN5OS2
    2-(4-fluorophenyl)-4-[[4-[[(2S)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-thiazole
    —— (Z)-1-[6-(4-chlorophenyl)sulfanylpyridin-3-yl]-N-[(3-fluorophenyl)methoxy]methanimine —— C19H14ClFN2OS
    (Z)-1-[6-(4-chlorophenyl)sulfanylpyridin-3-yl]-N-[(3-fluorophenyl)methoxy]methanimine
    —— 2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[4-[(1R)-1-phenylethyl]piperazin-1-yl]ethanone —— C24H34N6OS
    2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[4-[(1R)-1-phenylethyl]piperazin-1-yl]ethanone
    —— 2-(4-fluorophenyl)-4-[[4-[[(2R)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-thiazole —— C22H26FN5OS2
    2-(4-fluorophenyl)-4-[[4-[[(2R)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,3-thiazole
    —— (2Z)-2-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one —— C23H15N3O3S2
    (2Z)-2-[[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one
    —— [(2R)-2,3-dihydro-1-benzothiophen-2-yl]-[4-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazin-1-yl]methanone —— C20H20N4O2S2
    [(2R)-2,3-dihydro-1-benzothiophen-2-yl]-[4-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazin-1-yl]methanone
    —— N-benzyl-N-[(1R)-1-cyclopropylethyl]-2-[[5-[(E)-2-thiophen-2-ylethenyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C22H24N4OS2
    N-benzyl-N-[(1R)-1-cyclopropylethyl]-2-[[5-[(E)-2-thiophen-2-ylethenyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— N-[[(2S)-oxolan-2-yl]methyl]-5-quinazolin-4-ylsulfanyl-1,3,4-thiadiazol-2-amine —— C15H15N5OS2
    N-[[(2S)-oxolan-2-yl]methyl]-5-quinazolin-4-ylsulfanyl-1,3,4-thiadiazol-2-amine
    —— 2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[(S)-(1-methylimidazol-2-yl)-phenylmethyl]acetamide —— C25H29N7O2S
    2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[(S)-(1-methylimidazol-2-yl)-phenylmethyl]acetamide
    —— (2R)-N-cyclopropyl-2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]propanamide —— C18H25N5O2S
    (2R)-N-cyclopropyl-2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]propanamide
    —— N-[(S)-(1-methylimidazol-2-yl)-phenylmethyl]-2-[[5-(2-thiophen-2-ylethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C21H22N6OS3
    N-[(S)-(1-methylimidazol-2-yl)-phenylmethyl]-2-[[5-(2-thiophen-2-ylethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— 2-[(5-butylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(R)-(1-methylimidazol-2-yl)-phenylmethyl]acetamide —— C19H23N5OS3
    2-[(5-butylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(R)-(1-methylimidazol-2-yl)-phenylmethyl]acetamide
    —— (2R)-6-methyl-N-[(1-phenylcyclobutyl)methyl]-2,3-dihydro-1-benzothiophene-2-carboxamide —— C21H23NOS
    (2R)-6-methyl-N-[(1-phenylcyclobutyl)methyl]-2,3-dihydro-1-benzothiophene-2-carboxamide
    —— 2-[[5-morpholin-4-yl-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2,2,2-trifluoroethyl)acetamide —— C15H22F3N5O3S
    2-[[5-morpholin-4-yl-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2,2,2-trifluoroethyl)acetamide
    —— N-[(Z)-[4-(1,3-benzothiazol-2-ylsulfanyl)-3-nitrophenyl]methylideneamino]-2-(2-methylphenoxy)acetamide —— C23H18N4O4S2
    N-[(Z)-[4-(1,3-benzothiazol-2-ylsulfanyl)-3-nitrophenyl]methylideneamino]-2-(2-methylphenoxy)acetamide
    —— 6-amino-1-(2-methylpropyl)-5-[2-[[5-morpholin-4-yl-4-[[(2R)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]acetyl]pyrimidine-2,4-dione —— C21H31N7O5S
    6-amino-1-(2-methylpropyl)-5-[2-[[5-morpholin-4-yl-4-[[(2R)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]acetyl]pyrimidine-2,4-dione
    —— (2S)-N-cyclopropyl-2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]propanamide —— C18H25N5O2S
    (2S)-N-cyclopropyl-2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]propanamide
    —— (2S)-6-methyl-N-[(1-phenylcyclobutyl)methyl]-2,3-dihydro-1-benzothiophene-2-carboxamide —— C21H23NOS
    (2S)-6-methyl-N-[(1-phenylcyclobutyl)methyl]-2,3-dihydro-1-benzothiophene-2-carboxamide