摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(4-bromo-2,5-dimethylphenyl)sulfanyl-N-[(Z)-[4-(dimethylamino)phenyl]methylideneamino]acetamide —— C19H22BrN3OS
    2-(4-bromo-2,5-dimethylphenyl)sulfanyl-N-[(Z)-[4-(dimethylamino)phenyl]methylideneamino]acetamide
    —— N-methyl-N-[(Z)-[5-(2-nitrophenyl)sulfanylfuran-2-yl]methylideneamino]methanamine —— C13H13N3O3S
    N-methyl-N-[(Z)-[5-(2-nitrophenyl)sulfanylfuran-2-yl]methylideneamino]methanamine
    —— N-((1-cyclopentyl-5-(pyridin-2-yl)-1H-pyrazol-3-yl)methyl)-3-(phenylthio)propanamide —— C23H26N4OS
    N-((1-cyclopentyl-5-(pyridin-2-yl)-1H-pyrazol-3-yl)methyl)-3-(phenylthio)propanamide
    —— N-((1-cyclopentyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)methyl)-3-(phenylthio)propanamide —— C23H26N4OS
    N-((1-cyclopentyl-5-(pyridin-4-yl)-1H-pyrazol-3-yl)methyl)-3-(phenylthio)propanamide
    —— N-((1-methyl-5-(pyridin-2-yl)-1H-pyrazol-3-yl)methyl)-3-(phenylthio)propanamide —— C19H20N4OS
    N-((1-methyl-5-(pyridin-2-yl)-1H-pyrazol-3-yl)methyl)-3-(phenylthio)propanamide
    —— 3-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)-N-[(Z)-(4-methylsulfanylphenyl)methylideneamino]propanamide —— C15H18N4O2S
    3-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)-N-[(Z)-(4-methylsulfanylphenyl)methylideneamino]propanamide
    —— (NZ)-4-fluoro-N-[[2-methyl-1-(2-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide —— C28H20FN3O4S2
    (NZ)-4-fluoro-N-[[2-methyl-1-(2-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide
    —— (NZ)-4-fluoro-N-[[2-methyl-1-(4-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide —— C28H20FN3O4S2
    (NZ)-4-fluoro-N-[[2-methyl-1-(4-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide
    —— (NZ)-N-[[1-(4-chlorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide —— C26H19ClN2O2S3
    (NZ)-N-[[1-(4-chlorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide
    —— (NZ)-N-[[2-methyl-1-(4-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide —— C26H19N3O4S3
    (NZ)-N-[[2-methyl-1-(4-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide
    —— (NZ)-N-[[2-methyl-1-(2-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide —— C26H19N3O4S3
    (NZ)-N-[[2-methyl-1-(2-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide
    —— N-(oxan-4-yl)-3-phenylsulfanyl-N-(2,2,2-trifluoroethyl)propanamide —— C16H20F3NO2S
    N-(oxan-4-yl)-3-phenylsulfanyl-N-(2,2,2-trifluoroethyl)propanamide
    —— (NZ)-N-[[1-(4-fluorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide —— C26H19FN2O2S3
    (NZ)-N-[[1-(4-fluorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]thiophene-2-sulfonamide
    —— 2-(1-methyltetrazol-5-yl)sulfanyl-N-(oxan-4-yl)-N-(2,2,2-trifluoroethyl)acetamide —— C11H16F3N5O2S
    2-(1-methyltetrazol-5-yl)sulfanyl-N-(oxan-4-yl)-N-(2,2,2-trifluoroethyl)acetamide
    —— 3-[(Z)-(2,5-dimethoxyphenyl)methylideneamino]-6-(2-nitrophenyl)sulfanylthieno[2,3-d]pyrimidin-4-one —— C21H16N4O5S2
    3-[(Z)-(2,5-dimethoxyphenyl)methylideneamino]-6-(2-nitrophenyl)sulfanylthieno[2,3-d]pyrimidin-4-one
    —— 2-(4-fluorophenyl)sulfanyl-N-(oxan-4-yl)-N-(2,2,2-trifluoroethyl)acetamide —— C15H17F4NO2S
    2-(4-fluorophenyl)sulfanyl-N-(oxan-4-yl)-N-(2,2,2-trifluoroethyl)acetamide
    —— N-(3-(2-(dimethylamino)phenyl)prop-2-yn-1-yl)-2-((4-fluorophenyl)thio)acetamide —— C19H19FN2OS
    N-(3-(2-(dimethylamino)phenyl)prop-2-yn-1-yl)-2-((4-fluorophenyl)thio)acetamide
    —— (NZ)-N-[[1-(4-fluorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide —— C28H21FN2O2S2
    (NZ)-N-[[1-(4-fluorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide
    —— (NZ)-N-[[2-methyl-1-(2-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide —— C28H21N3O4S2
    (NZ)-N-[[2-methyl-1-(2-nitrophenyl)sulfanylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide
    —— N-(3-(4-(dimethylamino)phenyl)prop-2-yn-1-yl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide —— C15H18N6OS
    N-(3-(4-(dimethylamino)phenyl)prop-2-yn-1-yl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide
    —— 6-(2-nitrophenyl)sulfanyl-3-[(Z)-pyridin-2-ylmethylideneamino]thieno[2,3-d]pyrimidin-4-one —— C18H11N5O3S2
    6-(2-nitrophenyl)sulfanyl-3-[(Z)-pyridin-2-ylmethylideneamino]thieno[2,3-d]pyrimidin-4-one
    —— N-(3-(2-(dimethylamino)phenyl)prop-2-yn-1-yl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide —— C15H18N6OS
    N-(3-(2-(dimethylamino)phenyl)prop-2-yn-1-yl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide
    —— (NZ)-N-[[1-(4-chlorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide —— C28H21ClN2O2S2
    (NZ)-N-[[1-(4-chlorophenyl)sulfanyl-2-methylindolizin-3-yl]-phenylmethylidene]benzenesulfonamide
    —— N-[(E)-2-nitroso-1,2-bis(phenylsulfanyl)ethenyl]hydroxylamine —— C14H12N2O2S2
    N-[(E)-2-nitroso-1,2-bis(phenylsulfanyl)ethenyl]hydroxylamine
    —— N-(3-(3-chlorophenyl)prop-2-yn-1-yl)-2-(5-oxo-2,3,5,6,7,8-hexahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-3-yl)acetamide —— C20H18ClN3O2S
    N-(3-(3-chlorophenyl)prop-2-yn-1-yl)-2-(5-oxo-2,3,5,6,7,8-hexahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-3-yl)acetamide
    —— N-(3-(3-chlorophenyl)prop-2-yn-1-yl)-3-(phenylthio)propanamide —— C18H16ClNOS
    N-(3-(3-chlorophenyl)prop-2-yn-1-yl)-3-(phenylthio)propanamide
    —— N-(3-(2-chlorophenyl)prop-2-yn-1-yl)-2-(5-oxo-2,3,5,6,7,8-hexahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-3-yl)acetamide —— C20H18ClN3O2S
    N-(3-(2-chlorophenyl)prop-2-yn-1-yl)-2-(5-oxo-2,3,5,6,7,8-hexahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-3-yl)acetamide
    —— N-(3-(2-fluorophenyl)prop-2-yn-1-yl)-3-(phenylthio)propanamide —— C18H16FNOS
    N-(3-(2-fluorophenyl)prop-2-yn-1-yl)-3-(phenylthio)propanamide
    —— N-(3-(2-fluorophenyl)prop-2-yn-1-yl)-2-(5-oxo-2,3,5,6,7,8-hexahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-3-yl)acetamide —— C20H18FN3O2S
    N-(3-(2-fluorophenyl)prop-2-yn-1-yl)-2-(5-oxo-2,3,5,6,7,8-hexahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-3-yl)acetamide
    —— N-(3-(2-fluorophenyl)prop-2-yn-1-yl)-2-((4-fluorophenyl)thio)acetamide —— C17H13F2NOS
    N-(3-(2-fluorophenyl)prop-2-yn-1-yl)-2-((4-fluorophenyl)thio)acetamide
    —— N-(3-(4-fluorophenyl)prop-2-yn-1-yl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide —— C13H12FN5OS
    N-(3-(4-fluorophenyl)prop-2-yn-1-yl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide
    —— N-[(Z)-[2-methyl-5-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pyrazolo[1,5-a]quinazolin-3-yl]methylideneamino]-3-pyrrolidin-1-ylsulfonylbenzamide —— C26H25N9O3S2
    N-[(Z)-[2-methyl-5-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pyrazolo[1,5-a]quinazolin-3-yl]methylideneamino]-3-pyrrolidin-1-ylsulfonylbenzamide
    —— 2-(1,3-benzothiazol-2-ylsulfanyl)-3-[(Z)-hydroxyiminomethyl]-9-methylpyrido[1,2-a]pyrimidin-4-one —— C17H12N4O2S2
    2-(1,3-benzothiazol-2-ylsulfanyl)-3-[(Z)-hydroxyiminomethyl]-9-methylpyrido[1,2-a]pyrimidin-4-one
    —— 3-[(2Z)-2-[[5-[4-(difluoromethylsulfanyl)phenyl]furan-2-yl]methylidene]hydrazinyl]propanenitrile —— C15H13F2N3OS
    3-[(2Z)-2-[[5-[4-(difluoromethylsulfanyl)phenyl]furan-2-yl]methylidene]hydrazinyl]propanenitrile
    —— (2E,5S)-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-2-[(Z)-pyridin-3-ylmethylidenehydrazinylidene]-1,3-thiazolidin-4-one —— C17H14F2N4OS2
    (2E,5S)-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-2-[(Z)-pyridin-3-ylmethylidenehydrazinylidene]-1,3-thiazolidin-4-one
    —— N-[(Z)-[5-[4-(difluoromethylsulfanyl)phenyl]furan-2-yl]methylideneamino]-2-methylpropan-2-amine —— C16H18F2N2OS
    N-[(Z)-[5-[4-(difluoromethylsulfanyl)phenyl]furan-2-yl]methylideneamino]-2-methylpropan-2-amine
    —— 2-(1,3-benzothiazol-2-ylsulfanyl)-3-[(Z)-(tert-butylhydrazinylidene)methyl]-9-methylpyrido[1,2-a]pyrimidin-4-one —— C21H21N5OS2
    2-(1,3-benzothiazol-2-ylsulfanyl)-3-[(Z)-(tert-butylhydrazinylidene)methyl]-9-methylpyrido[1,2-a]pyrimidin-4-one
    —— [[3-Ethoxycarbonyl-5-(2-nitrophenyl)sulfanyl-4-phenylthiophen-2-yl]amino]methylidene-dimethylazanium —— C22H22N3O4S2+
    [[3-Ethoxycarbonyl-5-(2-nitrophenyl)sulfanyl-4-phenylthiophen-2-yl]amino]methylidene-dimethylazanium
    —— (2E,5S)-2-[(Z)-[5-(2-chlorophenyl)furan-2-yl]methylidenehydrazinylidene]-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazolidin-4-one —— C22H16ClF2N3O2S2
    (2E,5S)-2-[(Z)-[5-(2-chlorophenyl)furan-2-yl]methylidenehydrazinylidene]-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazolidin-4-one
    —— (E)-3-nitro-4-(p-tolylthio)benzaldehyde oxime —— C14H12N2O3S
    (E)-3-nitro-4-(p-tolylthio)benzaldehyde oxime
    —— 3-Nitro-4-(phenylsulfanyl)benzenecarbaldehydeo-(3,4-dichlorobenzyl)oxime —— C20H14Cl2N2O3S
    3-Nitro-4-(phenylsulfanyl)benzenecarbaldehydeo-(3,4-dichlorobenzyl)oxime
    —— 3-Nitro-4-(phenylsulfanyl)benzenecarbaldehydeo-(2,6-dichlorobenzyl)oxime —— C20H14Cl2N2O3S
    3-Nitro-4-(phenylsulfanyl)benzenecarbaldehydeo-(2,6-dichlorobenzyl)oxime
    —— 3-Nitro-4-(phenylsulfanyl)benzenecarbaldehydeo-(2,4-dichlorobenzyl)oxime —— C20H14Cl2N2O3S
    3-Nitro-4-(phenylsulfanyl)benzenecarbaldehydeo-(2,4-dichlorobenzyl)oxime
    —— 2-((4-fluorophenyl)thio)-N-(2-(6-oxo-3-(1H-pyrazol-1-yl)pyridazin-1(6H)-yl)ethyl)acetamide —— C17H16FN5O2S
    2-((4-fluorophenyl)thio)-N-(2-(6-oxo-3-(1H-pyrazol-1-yl)pyridazin-1(6H)-yl)ethyl)acetamide
    —— 3-(2-(7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)-2-oxoethyl)-2,3,7,8-tetrahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-5(6H)-one —— C19H25N3O4S
    3-(2-(7,7-dimethyl-6,8-dioxa-2-azaspiro[3.5]nonan-2-yl)-2-oxoethyl)-2,3,7,8-tetrahydrocyclopenta[d]thiazolo[3,2-a]pyrimidin-5(6H)-one
    —— N-(but-3-yn-1-yl)-2-((4-fluorophenyl)thio)acetamide —— C12H12FNOS
    N-(but-3-yn-1-yl)-2-((4-fluorophenyl)thio)acetamide
    —— N-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-carboxamide —— C11H13N5O2S2
    N-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-carboxamide
    —— N-(2-cyclopropyl-2-hydroxy-2-phenylethyl)-3-(phenylthio)propanamide —— C20H23NO2S
    N-(2-cyclopropyl-2-hydroxy-2-phenylethyl)-3-(phenylthio)propanamide
    —— 2-((4-fluorophenyl)thio)-N-(2-hydroxy-3-phenylpropyl)acetamide —— C17H18FNO2S
    2-((4-fluorophenyl)thio)-N-(2-hydroxy-3-phenylpropyl)acetamide
    —— 1-[4-(2-Imidazol-1-ylethyl)piperazin-1-yl]-2-(1-methyltetrazol-5-yl)sulfanylethanone —— C13H20N8OS
    1-[4-(2-Imidazol-1-ylethyl)piperazin-1-yl]-2-(1-methyltetrazol-5-yl)sulfanylethanone