摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (3S)-3-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]thiolane-3-carboxylic acid —— C8H11N3O2S2
    (3S)-3-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]thiolane-3-carboxylic acid
    —— (2R)-2-(3-aminopyridin-2-yl)sulfanyl-2-cyclopropylpropanoic acid —— C11H14N2O2S
    (2R)-2-(3-aminopyridin-2-yl)sulfanyl-2-cyclopropylpropanoic acid
    —— (2S)-2-methyl-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]butanoic acid —— C8H13N3O2S
    (2S)-2-methyl-2-[(5-methyl-1H-1,2,4-triazol-3-yl)sulfanyl]butanoic acid
    —— N-(dicyclopropylmethyl)-4-phenylsulfanylbutanamide —— C17H23NOS
    N-(dicyclopropylmethyl)-4-phenylsulfanylbutanamide
    —— (2R)-2-(2-aminophenyl)sulfanyl-2-methylbutanoic acid —— C11H15NO2S
    (2R)-2-(2-aminophenyl)sulfanyl-2-methylbutanoic acid
    —— (3R)-3-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]thiolane-3-carboxylic acid —— C7H10N4O2S2
    (3R)-3-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]thiolane-3-carboxylic acid
    —— (3S)-3-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]thiolane-3-carboxylic acid —— C7H10N4O2S2
    (3S)-3-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]thiolane-3-carboxylic acid
    —— (3R)-3-(1,3,4-thiadiazol-2-ylsulfanyl)thiolane-3-carboxylic acid —— C7H8N2O2S3
    (3R)-3-(1,3,4-thiadiazol-2-ylsulfanyl)thiolane-3-carboxylic acid
    —— (2R)-2-cyclopropyl-2-(1,3-thiazol-2-ylsulfanyl)propanoic acid —— C9H11NO2S2
    (2R)-2-cyclopropyl-2-(1,3-thiazol-2-ylsulfanyl)propanoic acid
    —— (2R)-2-cyclopropyl-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]propanoic acid —— C9H12N2O2S2
    (2R)-2-cyclopropyl-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]propanoic acid
    —— (2R)-2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]-2-cyclopropylpropanoic acid —— C8H12N4O2S
    (2R)-2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]-2-cyclopropylpropanoic acid
    —— (2R)-2-cyclopropyl-2-pyridin-2-ylsulfanylpropanoic acid —— C11H13NO2S
    (2R)-2-cyclopropyl-2-pyridin-2-ylsulfanylpropanoic acid
    —— (3R)-3-pyrimidin-2-ylsulfanylthiolane-3-carboxylic acid —— C9H10N2O2S2
    (3R)-3-pyrimidin-2-ylsulfanylthiolane-3-carboxylic acid
    —— (3S)-3-(1-methyltetrazol-5-yl)sulfanylthiolane-3-carboxylic acid —— C7H10N4O2S2
    (3S)-3-(1-methyltetrazol-5-yl)sulfanylthiolane-3-carboxylic acid
    —— (2S)-2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-2-cyclopropylpropanoic acid —— C8H12N4O2S
    (2S)-2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-2-cyclopropylpropanoic acid
    —— (3R)-3-(1,3-thiazol-2-ylsulfanyl)thiolane-3-carboxylic acid —— C8H9NO2S3
    (3R)-3-(1,3-thiazol-2-ylsulfanyl)thiolane-3-carboxylic acid
    —— (2R)-2-(4,6-diaminopyrimidin-2-yl)sulfanyl-2-methylbutanoic acid —— C9H14N4O2S
    (2R)-2-(4,6-diaminopyrimidin-2-yl)sulfanyl-2-methylbutanoic acid
    —— (2S)-2-cyclopropyl-2-(4-hydroxyphenyl)sulfanylpropanoic acid —— C12H14O3S
    (2S)-2-cyclopropyl-2-(4-hydroxyphenyl)sulfanylpropanoic acid
    —— (2R)-2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-2-cyclopropylpropanoic acid —— C8H12N4O2S
    (2R)-2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-2-cyclopropylpropanoic acid
    —— (3R)-3-(1H-1,2,4-triazol-5-ylsulfanyl)thiolane-3-carboxylic acid —— C7H9N3O2S2
    (3R)-3-(1H-1,2,4-triazol-5-ylsulfanyl)thiolane-3-carboxylic acid
    —— 2-(2-cyanophenyl)sulfanyl-N-[3-[methyl(methylsulfonyl)amino]propyl]benzamide —— C19H21N3O3S2
    2-(2-cyanophenyl)sulfanyl-N-[3-[methyl(methylsulfonyl)amino]propyl]benzamide
    —— (2R)-2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-2-cyclopropylpropanoic acid —— C8H11N3O2S2
    (2R)-2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-2-cyclopropylpropanoic acid
    —— (2S)-2-cyclopropyl-2-pyrimidin-2-ylsulfanylpropanoic acid —— C10H12N2O2S
    (2S)-2-cyclopropyl-2-pyrimidin-2-ylsulfanylpropanoic acid
    —— (2R)-2-cyclopropyl-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoic acid —— C9H13N3O2S
    (2R)-2-cyclopropyl-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoic acid
    —— 3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]ethyl]propanamide —— C18H30N4O2S
    3-(4,6-dimethyl-2-methylsulfanylpyrimidin-5-yl)-N-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]ethyl]propanamide
    —— (2S)-2-methylsulfanyl-2-(4-methylsulfanylphenyl)propanoic acid —— C11H14O2S2
    (2S)-2-methylsulfanyl-2-(4-methylsulfanylphenyl)propanoic acid
    —— (2S)-2-methyl-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]butanoic acid —— C8H12N2O2S2
    (2S)-2-methyl-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]butanoic acid
    —— (2R)-2-cyclopropyl-2-(1-methyltetrazol-5-yl)sulfanylpropanoic acid —— C8H12N4O2S
    (2R)-2-cyclopropyl-2-(1-methyltetrazol-5-yl)sulfanylpropanoic acid
    —— (1S,2S)-2-methyl-1-(1H-1,2,4-triazol-5-ylsulfanyl)cyclohexane-1-carboxylic acid —— C10H15N3O2S
    (1S,2S)-2-methyl-1-(1H-1,2,4-triazol-5-ylsulfanyl)cyclohexane-1-carboxylic acid
    —— N-[(2R)-3-methyl-2-morpholin-4-ylbutyl]-2-(2-methylphenyl)sulfanylacetamide —— C18H28N2O2S
    N-[(2R)-3-methyl-2-morpholin-4-ylbutyl]-2-(2-methylphenyl)sulfanylacetamide
    —— (1R,2R)-2-methyl-1-(1H-1,2,4-triazol-5-ylsulfanyl)cyclohexane-1-carboxylic acid —— C10H15N3O2S
    (1R,2R)-2-methyl-1-(1H-1,2,4-triazol-5-ylsulfanyl)cyclohexane-1-carboxylic acid
    —— (3S)-3-thiophen-2-ylsulfanylthiolane-3-carboxylic acid —— C9H10O2S3
    (3S)-3-thiophen-2-ylsulfanylthiolane-3-carboxylic acid
    —— (3R)-3-thiophen-2-ylsulfanylthiolane-3-carboxylic acid —— C9H10O2S3
    (3R)-3-thiophen-2-ylsulfanylthiolane-3-carboxylic acid
    —— dimethyl (1'R,3'R,5'R,7'S)-6'-oxospiro[1,3-dithiolane-2,2'-bicyclo[3.3.1]nonane]-3',7'-dicarboxylate —— C15H20O5S2
    dimethyl (1'R,3'R,5'R,7'S)-6'-oxospiro[1,3-dithiolane-2,2'-bicyclo[3.3.1]nonane]-3',7'-dicarboxylate
    —— N-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-methylpropyl]-2-(4-methylphenyl)sulfanylacetamide —— C19H30N2O2S
    N-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-methylpropyl]-2-(4-methylphenyl)sulfanylacetamide
    —— N-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-methylpropyl]-3-(2-fluorophenyl)sulfanylpropanamide —— C19H29FN2O2S
    N-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-methylpropyl]-3-(2-fluorophenyl)sulfanylpropanamide
    —— (2R)-N,N-dimethyl-2-[4-(trifluoromethyl)pyrimidin-2-yl]sulfanylpropanamide —— C10H12F3N3OS
    (2R)-N,N-dimethyl-2-[4-(trifluoromethyl)pyrimidin-2-yl]sulfanylpropanamide
    —— 3-(4-fluorophenyl)sulfanyl-N-[(3R)-3-methyl-1,1-dioxothiolan-3-yl]propanamide —— C14H18FNO3S2
    3-(4-fluorophenyl)sulfanyl-N-[(3R)-3-methyl-1,1-dioxothiolan-3-yl]propanamide
    —— N-[(2S)-3-methyl-2-morpholin-4-ylbutyl]-2-phenylsulfanylpyridine-3-carboxamide —— C21H27N3O2S
    N-[(2S)-3-methyl-2-morpholin-4-ylbutyl]-2-phenylsulfanylpyridine-3-carboxamide
    —— 2-[(4-methoxyphenyl)methyl]-5-quinoxalin-2-ylsulfanyl-1,3,4-oxadiazole —— C18H14N4O2S
    2-[(4-methoxyphenyl)methyl]-5-quinoxalin-2-ylsulfanyl-1,3,4-oxadiazole
    —— (2Z,5S)-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-2-[(Z)-[4-(dimethylamino)phenyl]methylidenehydrazinylidene]-1,3-thiazolidin-4-one —— C20H20F2N4OS2
    (2Z,5S)-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-2-[(Z)-[4-(dimethylamino)phenyl]methylidenehydrazinylidene]-1,3-thiazolidin-4-one
    —— (2E,5S)-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-2-[(Z)-pyridin-2-ylmethylidenehydrazinylidene]-1,3-thiazolidin-4-one —— C17H14F2N4OS2
    (2E,5S)-5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-2-[(Z)-pyridin-2-ylmethylidenehydrazinylidene]-1,3-thiazolidin-4-one
    —— tert-butyl N-[(1R)-1-[5-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]-3-methylsulfanylpropyl]carbamate —— C17H25N5O5S2
    tert-butyl N-[(1R)-1-[5-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]-3-methylsulfanylpropyl]carbamate
    —— (2S)-N-(2-imidazol-1-ylethyl)-6-methyl-2,3-dihydro-1-benzothiophene-2-carboxamide —— C15H17N3OS
    (2S)-N-(2-imidazol-1-ylethyl)-6-methyl-2,3-dihydro-1-benzothiophene-2-carboxamide
    —— 3-(2-benzylsulfanyl-6-methyl-4-oxo-1H-pyrimidin-5-yl)-N-(2,2,2-trifluoroethyl)propanamide —— C17H18F3N3O2S
    3-(2-benzylsulfanyl-6-methyl-4-oxo-1H-pyrimidin-5-yl)-N-(2,2,2-trifluoroethyl)propanamide
    —— 3-(2-methylpropyl)-5-[[1-(2-thiophen-2-ylethyl)tetrazol-5-yl]sulfanylmethyl]-1,2,4-oxadiazole —— C14H18N6OS2
    3-(2-methylpropyl)-5-[[1-(2-thiophen-2-ylethyl)tetrazol-5-yl]sulfanylmethyl]-1,2,4-oxadiazole
    —— 4-(4-chlorophenyl)sulfanyl-N-[[(2S)-oxolan-2-yl]methyl]butanamide —— C15H20ClNO2S
    4-(4-chlorophenyl)sulfanyl-N-[[(2S)-oxolan-2-yl]methyl]butanamide
    —— [(2R)-1-(furan-2-ylmethylamino)-1-oxopropan-2-yl] 2-(2-chlorophenyl)sulfanylacetate —— C16H16ClNO4S
    [(2R)-1-(furan-2-ylmethylamino)-1-oxopropan-2-yl] 2-(2-chlorophenyl)sulfanylacetate
    —— (2R)-1-(4-ethylpiperazin-1-yl)-2-[(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]propan-1-one —— C13H22N4OS3
    (2R)-1-(4-ethylpiperazin-1-yl)-2-[(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]propan-1-one
    —— N-[(1R)-1-(2,4-difluorophenyl)ethyl]-2-[(4-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C15H18F2N4OS
    N-[(1R)-1-(2,4-difluorophenyl)ethyl]-2-[(4-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide