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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-Amino-6-(pyridin-2-ylmethylsulfanyl)-4-thiophen-2-ylpyridin-1-ium-3,5-dicarbonitrile —— C17H12N5S2+
    2-Amino-6-(pyridin-2-ylmethylsulfanyl)-4-thiophen-2-ylpyridin-1-ium-3,5-dicarbonitrile
    —— (2S)-N-[(1S)-1-(4-methylsulfanylphenyl)ethyl]-2-propan-2-ylsulfonylpropanamide —— C15H23NO3S2
    (2S)-N-[(1S)-1-(4-methylsulfanylphenyl)ethyl]-2-propan-2-ylsulfonylpropanamide
    —— (2R)-1-(4-acetylpiperazin-1-yl)-2-(4-hydroxyphenyl)sulfanylpropan-1-one —— C15H20N2O3S
    (2R)-1-(4-acetylpiperazin-1-yl)-2-(4-hydroxyphenyl)sulfanylpropan-1-one
    —— 2-methyl-N-[(1S)-1-(4-methylsulfanylphenyl)ethyl]propanamide —— C13H19NOS
    2-methyl-N-[(1S)-1-(4-methylsulfanylphenyl)ethyl]propanamide
    —— 2-(2-chlorophenyl)sulfanyl-N-[(2S)-1-methoxypropan-2-yl]acetamide —— C12H16ClNO2S
    2-(2-chlorophenyl)sulfanyl-N-[(2S)-1-methoxypropan-2-yl]acetamide
    —— Diaminomethylidene-(2-phenylsulfanylethenylamino)azanium —— C9H13N4S+
    Diaminomethylidene-(2-phenylsulfanylethenylamino)azanium
    —— 2-(2-Phenylsulfanylethenylamino)guanidine —— C9H12N4S
    2-(2-Phenylsulfanylethenylamino)guanidine
    —— 4-methyl-3-[2-[(1S,2R)-2-methylcyclohexyl]oxyethylsulfanyl]-5-(trifluoromethyl)-1,2,4-triazole —— C13H20F3N3OS
    4-methyl-3-[2-[(1S,2R)-2-methylcyclohexyl]oxyethylsulfanyl]-5-(trifluoromethyl)-1,2,4-triazole
    —— 4-methyl-3-[2-[(1R,2R)-2-methylcyclohexyl]oxyethylsulfanyl]-5-(trifluoromethyl)-1,2,4-triazole —— C13H20F3N3OS
    4-methyl-3-[2-[(1R,2R)-2-methylcyclohexyl]oxyethylsulfanyl]-5-(trifluoromethyl)-1,2,4-triazole
    —— 2-(2,4-difluorophenyl)sulfanyl-N-[(2R)-1-methoxypropan-2-yl]acetamide —— C12H15F2NO2S
    2-(2,4-difluorophenyl)sulfanyl-N-[(2R)-1-methoxypropan-2-yl]acetamide
    —— 2-(2-chlorophenyl)sulfanyl-N-[(2R)-1-methoxypropan-2-yl]acetamide —— C12H16ClNO2S
    2-(2-chlorophenyl)sulfanyl-N-[(2R)-1-methoxypropan-2-yl]acetamide
    —— 3-(2-fluorophenyl)sulfanyl-N-[(1R)-1-(3-methyl-1,2,4-oxadiazol-5-yl)ethyl]propanamide —— C14H16FN3O2S
    3-(2-fluorophenyl)sulfanyl-N-[(1R)-1-(3-methyl-1,2,4-oxadiazol-5-yl)ethyl]propanamide
    —— (2R)-N-methyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C14H20N2OS
    (2R)-N-methyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2S)-2-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C17H26N2OS
    (2S)-2-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— 3-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    3-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-ethyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide —— C14H20N2OS
    N-ethyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide
    —— 3-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C17H26N2OS
    3-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-ethyl-3-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    N-ethyl-3-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2R)-2-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    (2R)-2-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— (2S)-N-ethyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    (2S)-N-ethyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2S)-2-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    (2S)-2-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— 2-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]acetamide —— C15H22N2OS
    2-phenylsulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]acetamide
    —— 2-phenylsulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]acetamide —— C15H22N2OS
    2-phenylsulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]acetamide
    —— (2R)-2-phenylsulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    (2R)-2-phenylsulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2S)-N-ethyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    (2S)-N-ethyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— N-ethyl-3-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    N-ethyl-3-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— (2S)-2-phenylsulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    (2S)-2-phenylsulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— 2-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]acetamide —— C16H24N2OS
    2-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3R)-pyrrolidin-3-yl]acetamide
    —— 3-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C17H26N2OS
    3-(4-methylphenyl)sulfanyl-N-propan-2-yl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2R)-N-ethyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    (2R)-N-ethyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— (2R)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    (2R)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— N-methyl-3-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C14H20N2OS
    N-methyl-3-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— N-methyl-3-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C14H20N2OS
    N-methyl-3-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-methyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]acetamide —— C13H18N2OS
    N-methyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]acetamide
    —— (2S)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    (2S)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2S)-2-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C14H20N2OS
    (2S)-2-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-ethyl-3-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    N-ethyl-3-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-ethyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide —— C15H22N2OS
    N-ethyl-2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide
    —— 3-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C13H18N2OS
    3-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— (2S)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    (2S)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-methyl-3-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    N-methyl-3-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-ethyl-3-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C16H24N2OS
    N-ethyl-3-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2S)-N-methyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C14H20N2OS
    (2S)-N-methyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— 3-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C13H18N2OS
    3-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2S)-N-methyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C14H20N2OS
    (2S)-N-methyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide
    —— (2R)-N-methyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C14H20N2OS
    (2R)-N-methyl-2-phenylsulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— (2R)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide —— C15H22N2OS
    (2R)-N-methyl-2-(4-methylphenyl)sulfanyl-N-[(3R)-pyrrolidin-3-yl]propanamide
    —— N-methyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide —— C13H18N2OS
    N-methyl-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide
    —— 2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide —— C13H18N2OS
    2-(4-methylphenyl)sulfanyl-N-[(3S)-pyrrolidin-3-yl]acetamide
    —— (2S)-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide —— C13H18N2OS
    (2S)-2-phenylsulfanyl-N-[(3S)-pyrrolidin-3-yl]propanamide