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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-Ethylsulfanyl-3-(4-fluorophenyl)sulfanyl-5,7-dimethylpyrazolo[1,5-a]pyrimidine —— C16H16FN3S2
    2-Ethylsulfanyl-3-(4-fluorophenyl)sulfanyl-5,7-dimethylpyrazolo[1,5-a]pyrimidine
    —— N-ethyl-5-methoxy-1,2-dihydro-[1,3]thiazolo[5,4-b]pyridin-2-amine —— C9H13N3OS
    N-ethyl-5-methoxy-1,2-dihydro-[1,3]thiazolo[5,4-b]pyridin-2-amine
    —— 4-methylidene-3,7-dihydro-2H-1,3-thiazepine-2,7-diamine —— C6H11N3S
    4-methylidene-3,7-dihydro-2H-1,3-thiazepine-2,7-diamine
    —— 3-[Methyl(oxo)silyl]propane-1-thiol —— C4H10OSSi
    3-[Methyl(oxo)silyl]propane-1-thiol
    —— [2-Methylsulfanyl-4-(prop-2-enylamino)pyrimidin-5-yl]methanol —— C9H13N3OS
    [2-Methylsulfanyl-4-(prop-2-enylamino)pyrimidin-5-yl]methanol
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine —— C16H15BrN4S2
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine
    —— (Z)-1-(3-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]methanimine —— C17H14Br2N4S
    (Z)-1-(3-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine —— C18H17BrN4S2
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine —— C20H21BrN4S2
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine —— C17H14BrFN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-thiophen-2-ylmethanimine —— C17H17BrN4S2
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-thiophen-2-ylmethanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(3-chlorophenyl)methanimine —— C19H18BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(3-chlorophenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(2-chlorophenyl)methanimine —— C17H14BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(2-chlorophenyl)methanimine
    —— (Z)-1-(5-bromofuran-2-yl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]methanimine —— C17H16Br2N4OS
    (Z)-1-(5-bromofuran-2-yl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-methylphenyl)methanimine —— C20H21BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-methylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(2-chlorophenyl)methanimine —— C19H18BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(2-chlorophenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(3-methylphenyl)methanimine —— C18H17BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(3-methylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine —— C19H18BrFN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(2-methylphenyl)methanimine —— C18H17BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(2-methylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine —— C18H19BrN4S2
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine
    —— 4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]iminomethyl]-N,N-dimethylaniline —— C19H20BrN5S
    4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]iminomethyl]-N,N-dimethylaniline
    —— (Z,E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-2-methyl-3-phenylprop-2-en-1-imine —— C22H23ClN4S
    (Z,E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-2-methyl-3-phenylprop-2-en-1-imine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-chlorophenyl)methanimine —— C19H18BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-chlorophenyl)methanimine
    —— (Z)-1-(2-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]methanimine —— C17H14Br2N4S
    (Z)-1-(2-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]methanimine
    —— 4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]iminomethyl]-N,N-diethylaniline —— C21H24BrN5S
    4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]iminomethyl]-N,N-diethylaniline
    —— (Z)-N-[3-[(4-chlorophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine —— C21H23ClN4S
    (Z)-N-[3-[(4-chlorophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(3-methylphenyl)methanimine —— C20H21BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(3-methylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine —— C19H18BrFN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine
    —— (Z)-1-(3-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]methanimine —— C19H18Br2N4S
    (Z)-1-(3-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine —— C20H21BrN4S2
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine —— C19H19BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine —— C21H23BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine
    —— (Z)-N-[3-[(4-chlorophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine —— C18H19ClN4S2
    (Z)-N-[3-[(4-chlorophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(3-chlorophenyl)methanimine —— C17H14BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-methyl-1,2,4-triazol-4-yl]-1-(3-chlorophenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine —— C18H19BrN4S2
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(2-methylphenyl)methanimine —— C20H21BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]-1-(2-methylphenyl)methanimine
    —— (Z)-1-(2-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]methanimine —— C19H18Br2N4S
    (Z)-1-(2-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]methanimine
    —— 4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]iminomethyl]-N,N-diethylaniline —— C23H28BrN5S
    4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]iminomethyl]-N,N-diethylaniline
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-chlorophenyl)methanimine —— C19H18BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-chlorophenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine —— C21H23BrN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine
    —— (Z)-1-(3-chlorophenyl)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]methanimine —— C16H12Cl2N4S
    (Z)-1-(3-chlorophenyl)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]methanimine
    —— (Z)-1-(5-bromofuran-2-yl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]methanimine —— C17H16Br2N4OS
    (Z)-1-(5-bromofuran-2-yl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propan-2-yl-1,2,4-triazol-4-yl]methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-chlorophenyl)methanimine —— C19H18BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(3-chlorophenyl)methanimine
    —— 4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]iminomethyl]-N,N-dimethylaniline —— C21H24BrN5S
    4-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]iminomethyl]-N,N-dimethylaniline
    —— (Z)-1-(2-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]methanimine —— C19H18Br2N4S
    (Z)-1-(2-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine —— C19H18BrFN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine
    —— (Z)-1-(3-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]methanimine —— C19H18Br2N4S
    (Z)-1-(3-bromophenyl)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(2-chlorophenyl)methanimine —— C19H18BrClN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(2-chlorophenyl)methanimine
    —— (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine —— C19H18BrFN4S
    (Z)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine
    —— 3-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]iminomethyl]phenol —— C19H19BrN4OS
    3-[(Z)-[3-[(4-bromophenyl)methylsulfanyl]-5-propyl-1,2,4-triazol-4-yl]iminomethyl]phenol