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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-2-(6-aminopyridin-3-yl)sulfanylbutanamide —— C9H13N3OS
    (2S)-2-(6-aminopyridin-3-yl)sulfanylbutanamide
    —— (2S)-2-[(6-amino-4-oxo-1H-pyrimidin-2-yl)sulfanyl]butanamide —— C8H12N4O2S
    (2S)-2-[(6-amino-4-oxo-1H-pyrimidin-2-yl)sulfanyl]butanamide
    —— (2S)-2-(4-amino-2-fluorophenyl)sulfanylbutanamide —— C10H13FN2OS
    (2S)-2-(4-amino-2-fluorophenyl)sulfanylbutanamide
    —— (2R)-2-(3-aminopyridin-4-yl)sulfanylbutanamide —— C9H13N3OS
    (2R)-2-(3-aminopyridin-4-yl)sulfanylbutanamide
    —— (2S)-2-(4-amino-2-chlorophenyl)sulfanylbutanamide —— C10H13ClN2OS
    (2S)-2-(4-amino-2-chlorophenyl)sulfanylbutanamide
    —— (2S)-2-(4-amino-2-methylphenyl)sulfanylbutanamide —— C11H16N2OS
    (2S)-2-(4-amino-2-methylphenyl)sulfanylbutanamide
    —— (2S)-2-(2-amino-6-chlorophenyl)sulfanylbutanamide —— C10H13ClN2OS
    (2S)-2-(2-amino-6-chlorophenyl)sulfanylbutanamide
    —— (2R)-2-(2-amino-4-chlorophenyl)sulfanylbutanamide —— C10H13ClN2OS
    (2R)-2-(2-amino-4-chlorophenyl)sulfanylbutanamide
    —— (2S)-2-(3-aminopyridin-4-yl)sulfanylbutanamide —— C9H13N3OS
    (2S)-2-(3-aminopyridin-4-yl)sulfanylbutanamide
    —— (2R)-2-(6-aminopyridin-3-yl)sulfanylbutanamide —— C9H13N3OS
    (2R)-2-(6-aminopyridin-3-yl)sulfanylbutanamide
    —— (2S)-2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]butanamide —— C6H11N5OS
    (2S)-2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]butanamide
    —— (2R)-2-(4-amino-2-chlorophenyl)sulfanylbutanamide —— C10H13ClN2OS
    (2R)-2-(4-amino-2-chlorophenyl)sulfanylbutanamide
    —— (2R)-2-(2-amino-4-methylphenyl)sulfanylbutanamide —— C11H16N2OS
    (2R)-2-(2-amino-4-methylphenyl)sulfanylbutanamide
    —— (2S)-2-(5-aminopyridin-2-yl)sulfanylbutanamide —— C9H13N3OS
    (2S)-2-(5-aminopyridin-2-yl)sulfanylbutanamide
    —— (2R)-2-(2-aminophenyl)sulfanylbutanamide —— C10H14N2OS
    (2R)-2-(2-aminophenyl)sulfanylbutanamide
    —— (2R)-2-(2-amino-4-fluorophenyl)sulfanylbutanamide —— C10H13FN2OS
    (2R)-2-(2-amino-4-fluorophenyl)sulfanylbutanamide
    —— (2R)-2-(3-aminopyridin-2-yl)sulfanylbutanamide —— C9H13N3OS
    (2R)-2-(3-aminopyridin-2-yl)sulfanylbutanamide
    —— (2S)-2-(2-amino-4-chlorophenyl)sulfanylbutanamide —— C10H13ClN2OS
    (2S)-2-(2-amino-4-chlorophenyl)sulfanylbutanamide
    —— (2S)-2-(2-amino-4-methylphenyl)sulfanylbutanamide —— C11H16N2OS
    (2S)-2-(2-amino-4-methylphenyl)sulfanylbutanamide
    —— [(Z)-[2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-phenylethylidene]amino]thiourea —— C15H17N5S2
    [(Z)-[2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-1-phenylethylidene]amino]thiourea
    —— methyl N-[(Z)-(4-methylsulfanylphenyl)methylideneamino]carbamate —— C10H12N2O2S
    methyl N-[(Z)-(4-methylsulfanylphenyl)methylideneamino]carbamate
    —— [3-[(3-bromophenyl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine —— C13H12BrN3OS
    [3-[(3-bromophenyl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine
    —— [3-[(5-methylpyrimidin-2-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine —— C12H13N5OS
    [3-[(5-methylpyrimidin-2-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine
    —— [3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine —— C9H11N7OS
    [3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine
    —— [3-[(4-methyl-1,3-thiazol-2-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine —— C11H12N4OS2
    [3-[(4-methyl-1,3-thiazol-2-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine
    —— [3-[(4-methylphenyl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine —— C14H15N3OS
    [3-[(4-methylphenyl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine
    —— [3-[(1-methylimidazol-2-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine —— C11H13N5OS
    [3-[(1-methylimidazol-2-yl)sulfanylmethyl]-1H-pyridin-2-ylidene]-nitrosomethanamine
    —— N-[[(3R,8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-yl]methyl]-2-phenylsulfanylacetamide —— C16H22N2O2S
    N-[[(3R,8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-yl]methyl]-2-phenylsulfanylacetamide
    —— N-[[(3R,8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-yl]methyl]-2-(2-chlorophenyl)sulfanylacetamide —— C16H21ClN2O2S
    N-[[(3R,8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-yl]methyl]-2-(2-chlorophenyl)sulfanylacetamide
    —— N-[(Z)-[5-(4-methylphenyl)sulfanylfuran-2-yl]methylideneamino]acetamide —— C14H14N2O2S
    N-[(Z)-[5-(4-methylphenyl)sulfanylfuran-2-yl]methylideneamino]acetamide
    —— N-[[(3R,8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-yl]methyl]-2-(4-chlorophenyl)sulfanylacetamide —— C16H21ClN2O2S
    N-[[(3R,8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-yl]methyl]-2-(4-chlorophenyl)sulfanylacetamide
    —— 4,6-dimethyl-1-[(Z)-(4-methylsulfanylphenyl)methylideneamino]pyridin-2-one —— C15H16N2OS
    4,6-dimethyl-1-[(Z)-(4-methylsulfanylphenyl)methylideneamino]pyridin-2-one
    —— N-[(Z)-furan-2-ylmethylideneamino]-2-(4-methylphenyl)sulfanylacetamide —— C14H14N2O2S
    N-[(Z)-furan-2-ylmethylideneamino]-2-(4-methylphenyl)sulfanylacetamide
    —— 3-[(Z)-hydroxyiminomethyl]-7-methyl-2-(4-methylphenyl)sulfanylpyrido[1,2-a]pyrimidin-4-one —— C17H15N3O2S
    3-[(Z)-hydroxyiminomethyl]-7-methyl-2-(4-methylphenyl)sulfanylpyrido[1,2-a]pyrimidin-4-one
    —— 6-tert-butyl-4-[(Z)-(4-methylphenyl)methylideneamino]-3-methylsulfanyl-1,2,4-triazin-5-one —— C16H20N4OS
    6-tert-butyl-4-[(Z)-(4-methylphenyl)methylideneamino]-3-methylsulfanyl-1,2,4-triazin-5-one
    —— 2-methoxy-N-[(Z)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]acetamide 5926-86-3 C13H13N3O3S
    2-methoxy-N-[(Z)-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]acetamide
    —— (2R)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-thiophen-2-ylmethylideneamino]propanamide —— C14H16N4OS2
    (2R)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-thiophen-2-ylmethylideneamino]propanamide
    —— (2R)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-(3-hydroxyphenyl)methylideneamino]propanamide —— C16H18N4O2S
    (2R)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-(3-hydroxyphenyl)methylideneamino]propanamide
    —— 6-tert-butyl-4-[(Z)-(4-fluorophenyl)methylideneamino]-3-methylsulfanyl-1,2,4-triazin-5-one —— C15H17FN4OS
    6-tert-butyl-4-[(Z)-(4-fluorophenyl)methylideneamino]-3-methylsulfanyl-1,2,4-triazin-5-one
    —— (2S)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylpropanamide —— C16H17ClN4OS
    (2S)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylpropanamide
    —— (Z)-1-[5-(4-chlorophenyl)sulfanylfuran-2-yl]-N-(1,2,4-triazol-4-yl)methanimine —— C13H9ClN4OS
    (Z)-1-[5-(4-chlorophenyl)sulfanylfuran-2-yl]-N-(1,2,4-triazol-4-yl)methanimine
    —— 2-[2-[(1R)-1-cyclopropylethyl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid —— C11H14F2N2O2S
    2-[2-[(1R)-1-cyclopropylethyl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid
    —— 2-[2-[(2R)-butan-2-yl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid —— C10H14F2N2O2S
    2-[2-[(2R)-butan-2-yl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid
    —— 2-[2-[(2S)-butan-2-yl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid —— C10H14F2N2O2S
    2-[2-[(2S)-butan-2-yl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid
    —— (2R)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylpropanamide —— C16H17ClN4OS
    (2R)-N-[(Z)-(2-chlorophenyl)methylideneamino]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylpropanamide
    —— 2-[2-[(1S)-1-cyclopropylethyl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid —— C11H14F2N2O2S
    2-[2-[(1S)-1-cyclopropylethyl]-5-(difluoromethyl)pyrazol-3-yl]sulfanylacetic acid
    —— N-[(Z)-1-(4-chlorophenyl)ethylideneamino]-2-pyrimidin-2-ylsulfanylacetamide —— C14H13ClN4OS
    N-[(Z)-1-(4-chlorophenyl)ethylideneamino]-2-pyrimidin-2-ylsulfanylacetamide
    —— (2S)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-thiophen-2-ylmethylideneamino]propanamide —— C14H16N4OS2
    (2S)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-thiophen-2-ylmethylideneamino]propanamide
    —— (2S)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-(3-hydroxyphenyl)methylideneamino]propanamide —— C16H18N4O2S
    (2S)-2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[(Z)-(3-hydroxyphenyl)methylideneamino]propanamide
    —— N-[(Z)-(4-methylsulfanylphenyl)methylideneamino]cyclopropanecarboxamide —— C12H14N2OS
    N-[(Z)-(4-methylsulfanylphenyl)methylideneamino]cyclopropanecarboxamide