摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[(R)-(1-methylimidazol-2-yl)-phenylmethyl]acetamide —— C25H29N7O2S
    2-[[4-(furan-2-ylmethyl)-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[(R)-(1-methylimidazol-2-yl)-phenylmethyl]acetamide
    —— (2R)-N-[(5-sulfamoylthiophen-2-yl)methyl]-2,3-dihydro-1-benzothiophene-2-carboxamide —— C14H14N2O3S3
    (2R)-N-[(5-sulfamoylthiophen-2-yl)methyl]-2,3-dihydro-1-benzothiophene-2-carboxamide
    —— (2R)-N-(cyclohexylmethyl)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C19H31N5O2S
    (2R)-N-(cyclohexylmethyl)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— 2-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-(4-ethylphenyl)ethyl]acetamide —— C20H28N4OS
    2-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-(4-ethylphenyl)ethyl]acetamide
    —— 2-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-phenylbutyl]acetamide —— C20H28N4OS
    2-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-1-phenylbutyl]acetamide
    —— (2S)-6-methyl-N-[2-(N-methylanilino)ethyl]-2,3-dihydro-1-benzothiophene-2-carboxamide —— C19H22N2OS
    (2S)-6-methyl-N-[2-(N-methylanilino)ethyl]-2,3-dihydro-1-benzothiophene-2-carboxamide
    —— (2R)-N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-N-pentyl-2,3-dihydro-1-benzothiophene-2-carboxamide —— C22H30N4O3S
    (2R)-N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-N-pentyl-2,3-dihydro-1-benzothiophene-2-carboxamide
    —— (2S)-2-phenylsulfanyl-1-[4-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazin-1-yl]propan-1-one —— C20H22N4O2S2
    (2S)-2-phenylsulfanyl-1-[4-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazin-1-yl]propan-1-one
    —— 2-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-(4-ethylphenyl)ethyl]acetamide —— C20H28N4OS
    2-[[5-(cyclopentylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-(4-ethylphenyl)ethyl]acetamide
    —— 1,3-dimethyl-6-[[4-[[(2R)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanylmethyl]pyrimidine-2,4-dione —— C19H28N6O3S
    1,3-dimethyl-6-[[4-[[(2R)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanylmethyl]pyrimidine-2,4-dione
    —— (2S)-N-(cyclohexylmethyl)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C19H31N5O2S
    (2S)-N-(cyclohexylmethyl)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2R)-N-[(S)-cyclopropyl-(4-methylphenyl)methyl]-2-phenylsulfanylpropanamide —— C20H23NOS
    (2R)-N-[(S)-cyclopropyl-(4-methylphenyl)methyl]-2-phenylsulfanylpropanamide
    —— 4-(4-methylphenyl)-2-[(E)-2-[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]ethenyl]-1,3-thiazole —— C25H20N2O2S2
    4-(4-methylphenyl)-2-[(E)-2-[4-(4-methylphenyl)sulfanyl-3-nitrophenyl]ethenyl]-1,3-thiazole
    —— 1-[2,5-dimethyl-1-[[(2R)-oxolan-2-yl]methyl]pyrrol-3-yl]-2-[[4-[[(2R)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone —— C25H37N5O3S
    1-[2,5-dimethyl-1-[[(2R)-oxolan-2-yl]methyl]pyrrol-3-yl]-2-[[4-[[(2R)-oxolan-2-yl]methyl]-5-piperidin-1-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone
    —— (2S)-N-[(S)-cyclopropyl-(4-methylphenyl)methyl]-2-phenylsulfanylpropanamide —— C20H23NOS
    (2S)-N-[(S)-cyclopropyl-(4-methylphenyl)methyl]-2-phenylsulfanylpropanamide
    —— (2S)-2-[(5-anilino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(2,2,2-trifluoroethyl)propanamide —— C13H13F3N4OS2
    (2S)-2-[(5-anilino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(2,2,2-trifluoroethyl)propanamide
    —— 2-[2-[4-[(3S)-1,1-dioxothiolan-3-yl]piperazin-1-yl]-2-oxoethyl]sulfanyl-4,5,6-trimethylpyridine-3-carbonitrile —— C19H26N4O3S2
    2-[2-[4-[(3S)-1,1-dioxothiolan-3-yl]piperazin-1-yl]-2-oxoethyl]sulfanyl-4,5,6-trimethylpyridine-3-carbonitrile
    —— (2R)-2-[(5-anilino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(2,2,2-trifluoroethyl)propanamide —— C13H13F3N4OS2
    (2R)-2-[(5-anilino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-(2,2,2-trifluoroethyl)propanamide
    —— 2-chloro-5-[(2Z)-2-[[4-(4-chlorophenyl)sulfanyl-3-nitrophenyl]methylidene]hydrazinyl]benzoic acid —— C20H13Cl2N3O4S
    2-chloro-5-[(2Z)-2-[[4-(4-chlorophenyl)sulfanyl-3-nitrophenyl]methylidene]hydrazinyl]benzoic acid
    —— N-[(1R)-1-(3-chlorophenyl)ethyl]-2-[[5-(methylsulfanylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C14H16ClN3O2S2
    N-[(1R)-1-(3-chlorophenyl)ethyl]-2-[[5-(methylsulfanylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-cyclopropyl-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[4-[[(2S)-oxolan-2-yl]methyl]-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C20H26N4O4S3
    N-cyclopropyl-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[4-[[(2S)-oxolan-2-yl]methyl]-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 2-[(5-cyclopropyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylpropyl]acetamide —— C23H30N4O3S
    2-[(5-cyclopropyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylpropyl]acetamide
    —— 2-[[5-[(5S)-5-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-4-methyl-1,2,4-triazol-3-yl]sulfanylmethyl]-5-ethyl-1,3,4-oxadiazole —— C20H27N5OS2
    2-[[5-[(5S)-5-tert-butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-4-methyl-1,2,4-triazol-3-yl]sulfanylmethyl]-5-ethyl-1,3,4-oxadiazole
    —— 2-(5-acetyl-3-cyano-6-methylpyridin-2-yl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C19H21N3O2S2
    2-(5-acetyl-3-cyano-6-methylpyridin-2-yl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— N-[(2,4-dimethylphenyl)methyl]-2-[[5-[(3S)-1,1-dioxothiolan-3-yl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-N-methylacetamide —— C21H28N4O3S2
    N-[(2,4-dimethylphenyl)methyl]-2-[[5-[(3S)-1,1-dioxothiolan-3-yl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-N-methylacetamide
    —— (2S)-2-[[4-(furan-2-ylmethyl)-5-propan-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N,N-dimethylpropanamide —— C15H22N4O2S
    (2S)-2-[[4-(furan-2-ylmethyl)-5-propan-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N,N-dimethylpropanamide
    —— 2-[[4-cyclohexyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C22H28N4O2S2
    2-[[4-cyclohexyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— 4-butyl-3-[(2R)-3-(furan-2-ylmethoxy)-2-hydroxypropyl]sulfanyl-1H-1,2,4-triazol-5-one —— C14H21N3O4S
    4-butyl-3-[(2R)-3-(furan-2-ylmethoxy)-2-hydroxypropyl]sulfanyl-1H-1,2,4-triazol-5-one
    —— 2-[(5-cyclopropyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylpropyl]acetamide —— C23H30N4O3S
    2-[(5-cyclopropyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-methylpropyl]acetamide
    —— 2-[[5-(butylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-1-[4-[(1S)-1-phenylethyl]piperazin-1-yl]ethanone —— C20H29N5OS2
    2-[[5-(butylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-1-[4-[(1S)-1-phenylethyl]piperazin-1-yl]ethanone
    —— (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C13H20N4O3S2
    (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— 2-[[4-cyclohexyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C22H28N4O2S2
    2-[[4-cyclohexyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— N-methyl-5-[4-[(3R)-3-methylpiperidin-1-yl]sulfonyl-2-nitrophenyl]sulfanyl-1,3,4-thiadiazol-2-amine —— C15H19N5O4S3
    N-methyl-5-[4-[(3R)-3-methylpiperidin-1-yl]sulfonyl-2-nitrophenyl]sulfanyl-1,3,4-thiadiazol-2-amine
    —— 4-[4-methyl-5-[4-[(3R)-3-methylpiperidin-1-yl]sulfonyl-2-nitrophenyl]sulfanyl-1,2,4-triazol-3-yl]pyridine —— C20H22N6O4S2
    4-[4-methyl-5-[4-[(3R)-3-methylpiperidin-1-yl]sulfonyl-2-nitrophenyl]sulfanyl-1,2,4-triazol-3-yl]pyridine
    —— (3R)-3-methyl-1-[4-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonylpiperidine —— C20H23N5O4S3
    (3R)-3-methyl-1-[4-[[4-methyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonylpiperidine
    —— (7R)-4-[[4-ethyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine —— C20H21N5OS2
    (7R)-4-[[4-ethyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
    —— (7S)-4-[[4-(2-methoxyethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine —— C21H22N6OS2
    (7S)-4-[[4-(2-methoxyethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
    —— 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-thiophen-2-ylethyl]acetamide —— C16H22N4OS3
    2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(1S)-1-thiophen-2-ylethyl]acetamide
    —— (7R)-7-methyl-4-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine —— C19H18N6S2
    (7R)-7-methyl-4-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
    —— (3R)-1-[4-[[4-ethyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonyl-3-methylpiperidine —— C21H25N5O5S2
    (3R)-1-[4-[[4-ethyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonyl-3-methylpiperidine
    —— 4-[[4-(4-fluorophenyl)-5-[(1S)-1-piperidin-1-ylethyl]-1,2,4-triazol-3-yl]sulfanyl]-5,6-dimethylthieno[2,3-d]pyrimidine —— C23H25FN6S2
    4-[[4-(4-fluorophenyl)-5-[(1S)-1-piperidin-1-ylethyl]-1,2,4-triazol-3-yl]sulfanyl]-5,6-dimethylthieno[2,3-d]pyrimidine
    —— 4-[[4-(4-fluorophenyl)-5-[(1S)-1-piperidin-1-ylethyl]-1,2,4-triazol-3-yl]sulfanyl]thieno[2,3-d]pyrimidine —— C21H21FN6S2
    4-[[4-(4-fluorophenyl)-5-[(1S)-1-piperidin-1-ylethyl]-1,2,4-triazol-3-yl]sulfanyl]thieno[2,3-d]pyrimidine
    —— (3R)-3-methyl-1-[4-[[5-methyl-4-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonylpiperidine —— C22H25N5O4S2
    (3R)-3-methyl-1-[4-[[5-methyl-4-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonylpiperidine
    —— (3R)-1-[4-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-3-nitrophenyl]sulfonyl-3-methylpiperidine —— C22H25N5O4S2
    (3R)-1-[4-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-3-nitrophenyl]sulfonyl-3-methylpiperidine
    —— (3S)-3-methyl-1-[4-[[5-methyl-4-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonylpiperidine —— C22H25N5O4S2
    (3S)-3-methyl-1-[4-[[5-methyl-4-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonylpiperidine
    —— (3S)-1-[4-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonyl-3-methylpiperidine —— C20H23N5O5S2
    (3S)-1-[4-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-3-nitrophenyl]sulfonyl-3-methylpiperidine
    —— 2-(4-bromophenyl)sulfanyl-N-[[3-[(2-methylimidazol-1-yl)methyl]phenyl]methyl]acetamide —— C20H20BrN3OS
    2-(4-bromophenyl)sulfanyl-N-[[3-[(2-methylimidazol-1-yl)methyl]phenyl]methyl]acetamide
    —— (2R)-N-[(4-chlorophenyl)methyl]-2-[[5-(2-thiophen-2-ylethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C18H19ClN4OS3
    (2R)-N-[(4-chlorophenyl)methyl]-2-[[5-(2-thiophen-2-ylethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— (2S)-N-ethyl-2-[[5-(2-thiophen-2-ylethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide —— C13H18N4OS3
    (2S)-N-ethyl-2-[[5-(2-thiophen-2-ylethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanamide
    —— 5-[[1-(difluoromethyl)imidazol-2-yl]methylsulfanyl]-N-[[(2S)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine —— C12H15F2N5OS2
    5-[[1-(difluoromethyl)imidazol-2-yl]methylsulfanyl]-N-[[(2S)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine