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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— [(1S,2R,4R)-4-ethyl-2-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]cyclohexyl]methanamine —— C13H22N2S2
    [(1S,2R,4R)-4-ethyl-2-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]cyclohexyl]methanamine
    —— [(1S,2S)-2-(3,4-dimethylphenyl)sulfanylcycloheptyl]methanamine —— C16H25NS
    [(1S,2S)-2-(3,4-dimethylphenyl)sulfanylcycloheptyl]methanamine
    —— [(1R,2R)-2-(3,4-dimethylphenyl)sulfanylcycloheptyl]methanamine —— C16H25NS
    [(1R,2R)-2-(3,4-dimethylphenyl)sulfanylcycloheptyl]methanamine
    —— [(1R,2R,4S)-4-propyl-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclohexyl]methanamine —— C12H21N3S2
    [(1R,2R,4S)-4-propyl-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclohexyl]methanamine
    —— [(1S,2R,4S)-4-ethyl-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]cyclohexyl]methanamine —— C12H22N4S
    [(1S,2R,4S)-4-ethyl-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]cyclohexyl]methanamine
    —— [(1R,2R,4R)-4-propyl-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclohexyl]methanamine —— C12H21N3S2
    [(1R,2R,4R)-4-propyl-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclohexyl]methanamine
    —— [(1R,2R,4S)-4-propyl-2-pyridin-2-ylsulfanylcyclohexyl]methanamine —— C15H24N2S
    [(1R,2R,4S)-4-propyl-2-pyridin-2-ylsulfanylcyclohexyl]methanamine
    —— [(1R,2R,4R)-2-(3,4-dimethylphenyl)sulfanyl-4-ethylcyclohexyl]methanamine —— C17H27NS
    [(1R,2R,4R)-2-(3,4-dimethylphenyl)sulfanyl-4-ethylcyclohexyl]methanamine
    —— [(1R,2R)-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclohexyl]methanamine —— C9H15N3S2
    [(1R,2R)-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclohexyl]methanamine
    —— [(1S,2R)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]cyclopentyl]methanamine —— C9H16N4S
    [(1S,2R)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]cyclopentyl]methanamine
    —— (2R)-2-methyl-3-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylsulfanyl)propan-1-amine —— C11H20N4S
    (2R)-2-methyl-3-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-ylsulfanyl)propan-1-amine
    —— [(1S,2S)-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclopentyl]methanamine —— C8H13N3S2
    [(1S,2S)-2-(1,3,4-thiadiazol-2-ylsulfanyl)cyclopentyl]methanamine
    —— [(1S,2S)-2-(3,4-dimethylphenyl)sulfanylcyclohexyl]methanamine —— C15H23NS
    [(1S,2S)-2-(3,4-dimethylphenyl)sulfanylcyclohexyl]methanamine
    —— [(1S,2S)-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylcyclopentyl]methanamine —— C12H15F3N2S
    [(1S,2S)-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylcyclopentyl]methanamine
    —— (2S)-2-methyl-3-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-amine —— C7H14N4S
    (2S)-2-methyl-3-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propan-1-amine
    —— [(1R,2R,4R)-2-(2-chlorophenyl)sulfanyl-4-methylcyclohexyl]methanamine —— C14H20ClNS
    [(1R,2R,4R)-2-(2-chlorophenyl)sulfanyl-4-methylcyclohexyl]methanamine
    —— [(1S,2R)-2-(2,4-dimethylphenyl)sulfanylcyclohexyl]methanamine —— C15H23NS
    [(1S,2R)-2-(2,4-dimethylphenyl)sulfanylcyclohexyl]methanamine
    —— [(1R,2R)-2-(1,3,4-thiadiazol-2-ylsulfanyl)cycloheptyl]methanamine —— C10H17N3S2
    [(1R,2R)-2-(1,3,4-thiadiazol-2-ylsulfanyl)cycloheptyl]methanamine
    —— [(1R,2R,4R)-4-ethyl-2-(4-fluorophenyl)sulfanylcyclohexyl]methanamine —— C15H22FNS
    [(1R,2R,4R)-4-ethyl-2-(4-fluorophenyl)sulfanylcyclohexyl]methanamine
    —— [(1R,2S)-2-(1-methyltetrazol-5-yl)sulfanylcycloheptyl]methanamine —— C10H19N5S
    [(1R,2S)-2-(1-methyltetrazol-5-yl)sulfanylcycloheptyl]methanamine
    —— [(1S,2S)-2-(2,4-dimethylphenyl)sulfanylcycloheptyl]methanamine —— C16H25NS
    [(1S,2S)-2-(2,4-dimethylphenyl)sulfanylcycloheptyl]methanamine
    —— [(1S,2R,4S)-2-(2-bromophenyl)sulfanyl-4-ethylcyclohexyl]methanamine —— C15H22BrNS
    [(1S,2R,4S)-2-(2-bromophenyl)sulfanyl-4-ethylcyclohexyl]methanamine
    —— [(1R,2S)-2-pyridin-2-ylsulfanylcyclohexyl]methanamine —— C12H18N2S
    [(1R,2S)-2-pyridin-2-ylsulfanylcyclohexyl]methanamine
    —— [(1R,2S)-2-ethylsulfanylcycloheptyl]methanamine —— C10H21NS
    [(1R,2S)-2-ethylsulfanylcycloheptyl]methanamine
    —— [(1R,2S)-2-(2,4-dimethylphenyl)sulfanylcyclohexyl]methanamine —— C15H23NS
    [(1R,2S)-2-(2,4-dimethylphenyl)sulfanylcyclohexyl]methanamine
    —— [(1S,2S)-2-(4-fluorophenyl)sulfanylcyclopentyl]methanamine —— C12H16FNS
    [(1S,2S)-2-(4-fluorophenyl)sulfanylcyclopentyl]methanamine
    —— [(1S,2S)-2-(2,4-dimethylphenyl)sulfanylcyclohexyl]methanamine —— C15H23NS
    [(1S,2S)-2-(2,4-dimethylphenyl)sulfanylcyclohexyl]methanamine
    —— (2S)-3-ethylsulfanyl-2-methylpropan-1-amine —— C6H15NS
    (2S)-3-ethylsulfanyl-2-methylpropan-1-amine
    —— [(1R,2R,4S)-2-(3,4-difluorophenyl)sulfanyl-4-methylcyclohexyl]methanamine —— C14H19F2NS
    [(1R,2R,4S)-2-(3,4-difluorophenyl)sulfanyl-4-methylcyclohexyl]methanamine
    —— [(1R,2R,4R)-2-(2-chlorophenyl)sulfanyl-4-ethylcyclohexyl]methanamine —— C15H22ClNS
    [(1R,2R,4R)-2-(2-chlorophenyl)sulfanyl-4-ethylcyclohexyl]methanamine
    —— [(1R,2S)-2-(2,4-difluorophenyl)sulfanylcyclohexyl]methanamine —— C13H17F2NS
    [(1R,2S)-2-(2,4-difluorophenyl)sulfanylcyclohexyl]methanamine
    —— [(1S,2R)-2-(2-methylpropylsulfanyl)cyclopentyl]methanamine —— C10H21NS
    [(1S,2R)-2-(2-methylpropylsulfanyl)cyclopentyl]methanamine
    —— [(1R,2R,4R)-4-ethyl-2-phenylsulfanylcyclohexyl]methanamine —— C15H23NS
    [(1R,2R,4R)-4-ethyl-2-phenylsulfanylcyclohexyl]methanamine
    —— (2R)-3-(4-fluorophenyl)sulfanyl-2-methylpropan-1-amine —— C10H14FNS
    (2R)-3-(4-fluorophenyl)sulfanyl-2-methylpropan-1-amine
    —— [(1S,2S)-2-(1-methylimidazol-2-yl)sulfanylcyclohexyl]methanamine —— C11H19N3S
    [(1S,2S)-2-(1-methylimidazol-2-yl)sulfanylcyclohexyl]methanamine
    —— [(1S,2R,4S)-2-(2-bromophenyl)sulfanyl-4-methylcyclohexyl]methanamine —— C14H20BrNS
    [(1S,2R,4S)-2-(2-bromophenyl)sulfanyl-4-methylcyclohexyl]methanamine
    —— [(1S,2S)-2-thiophen-2-ylsulfanylcyclopentyl]methanamine —— C10H15NS2
    [(1S,2S)-2-thiophen-2-ylsulfanylcyclopentyl]methanamine
    —— [(1S,2R)-2-(4-fluorophenyl)sulfanylcyclopentyl]methanamine —— C12H16FNS
    [(1S,2R)-2-(4-fluorophenyl)sulfanylcyclopentyl]methanamine
    —— [(1S,2R,4S)-2-(2-chlorophenyl)sulfanyl-4-ethylcyclohexyl]methanamine —— C15H22ClNS
    [(1S,2R,4S)-2-(2-chlorophenyl)sulfanyl-4-ethylcyclohexyl]methanamine
    —— [(1S,2R,4R)-2-(2,4-difluorophenyl)sulfanyl-4-methylcyclohexyl]methanamine —— C14H19F2NS
    [(1S,2R,4R)-2-(2,4-difluorophenyl)sulfanyl-4-methylcyclohexyl]methanamine
    —— [(1S,2R)-2-(4-bromophenyl)sulfanylcycloheptyl]methanamine —— C14H20BrNS
    [(1S,2R)-2-(4-bromophenyl)sulfanylcycloheptyl]methanamine
    —— [(1S,2R,4R)-4-propyl-2-pyrimidin-2-ylsulfanylcyclohexyl]methanamine —— C14H23N3S
    [(1S,2R,4R)-4-propyl-2-pyrimidin-2-ylsulfanylcyclohexyl]methanamine
    —— (2R)-3-(2,4-difluorophenyl)sulfanyl-2-methylpropan-1-amine —— C10H13F2NS
    (2R)-3-(2,4-difluorophenyl)sulfanyl-2-methylpropan-1-amine
    —— [(1S,2R,4R)-2-(2-fluorophenyl)sulfanyl-4-methylcyclohexyl]methanamine —— C14H20FNS
    [(1S,2R,4R)-2-(2-fluorophenyl)sulfanyl-4-methylcyclohexyl]methanamine
    —— [(1R,2R,4S)-4-propyl-2-thiophen-2-ylsulfanylcyclohexyl]methanamine —— C14H23NS2
    [(1R,2R,4S)-4-propyl-2-thiophen-2-ylsulfanylcyclohexyl]methanamine
    —— [(1R,2S)-2-(1H-1,2,4-triazol-5-ylsulfanyl)cycloheptyl]methanamine —— C10H18N4S
    [(1R,2S)-2-(1H-1,2,4-triazol-5-ylsulfanyl)cycloheptyl]methanamine
    —— [(1R,2R,4S)-2-(2-chlorophenyl)sulfanyl-4-methylcyclohexyl]methanamine —— C14H20ClNS
    [(1R,2R,4S)-2-(2-chlorophenyl)sulfanyl-4-methylcyclohexyl]methanamine
    —— [(1S,2R,4S)-4-ethyl-2-(1-methylimidazol-2-yl)sulfanylcyclohexyl]methanamine —— C13H23N3S
    [(1S,2R,4S)-4-ethyl-2-(1-methylimidazol-2-yl)sulfanylcyclohexyl]methanamine
    —— [(1R,2R,4S)-2-(2-chlorophenyl)sulfanyl-4-ethylcyclohexyl]methanamine —— C15H22ClNS
    [(1R,2R,4S)-2-(2-chlorophenyl)sulfanyl-4-ethylcyclohexyl]methanamine
    —— [(1R,2R,4S)-4-methyl-2-(4-methylphenyl)sulfanylcyclohexyl]methanamine —— C15H23NS
    [(1R,2R,4S)-4-methyl-2-(4-methylphenyl)sulfanylcyclohexyl]methanamine