摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-N-cyclopentyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C16H18FN3O2S
    (2S)-N-cyclopentyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C14H14FN3O4S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— (2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-pyrrolidin-1-ylpropan-1-one —— C15H16FN3O2S
    (2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-pyrrolidin-1-ylpropan-1-one
    —— 1-[2,5-dimethyl-1-[[(2R)-oxolan-2-yl]methyl]pyrrol-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone —— C21H22FN3O3S
    1-[2,5-dimethyl-1-[[(2R)-oxolan-2-yl]methyl]pyrrol-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone
    —— 2-[[5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(1,2,5-trimethylpyrrol-3-yl)ethanone —— C17H16FN3O2S
    2-[[5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(1,2,5-trimethylpyrrol-3-yl)ethanone
    —— 2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methoxyethyl)acetamide —— C13H14FN3O3S
    2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methoxyethyl)acetamide
    —— N-[(1R)-1-(4-propan-2-ylsulfanylphenyl)ethyl]-3-(1,2,4-triazol-1-yl)propanamide —— C16H22N4OS
    N-[(1R)-1-(4-propan-2-ylsulfanylphenyl)ethyl]-3-(1,2,4-triazol-1-yl)propanamide
    —— 2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2S)-3-methylbutan-2-yl]acetamide —— C15H18FN3O2S
    2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2S)-3-methylbutan-2-yl]acetamide
    —— N-(2-cyanoethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-methylacetamide —— C14H13FN4O2S
    N-(2-cyanoethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-methylacetamide
    —— 2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)acetamide —— C14H16FN3O2S
    2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)acetamide
    —— 1-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone —— C18H16FN3O3S
    1-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone
    —— N-(1-adamantylmethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C21H24FN3O2S
    N-(1-adamantylmethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-[(3-chlorophenyl)methyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C17H13ClFN3O2S
    N-[(3-chlorophenyl)methyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— (2R)-1-morpholin-4-yl-2-[[5-(thiophen-2-ylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]propan-1-one —— C14H18N4O2S2
    (2R)-1-morpholin-4-yl-2-[[5-(thiophen-2-ylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]propan-1-one
    —— 1-[5-methylsulfanyl-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]piperidine —— C13H22N4OS
    1-[5-methylsulfanyl-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]piperidine
    —— N-[2-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15F2N3O2S
    N-[2-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-(2-cyanoethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C13H11FN4O2S
    N-(2-cyanoethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 1-[5-methylsulfanyl-4-[[(2R)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]piperidine —— C13H22N4OS
    1-[5-methylsulfanyl-4-[[(2R)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]piperidine
    —— 1-(1-Adamantyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone —— C20H21FN2O2S
    1-(1-Adamantyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone
    —— (2S)-1-morpholin-4-yl-2-[[5-(thiophen-2-ylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]propan-1-one —— C14H18N4O2S2
    (2S)-1-morpholin-4-yl-2-[[5-(thiophen-2-ylmethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]propan-1-one
    —— N-[(1S)-1-(4-propan-2-ylsulfanylphenyl)ethyl]-3-(1,2,4-triazol-1-yl)propanamide —— C16H22N4OS
    N-[(1S)-1-(4-propan-2-ylsulfanylphenyl)ethyl]-3-(1,2,4-triazol-1-yl)propanamide
    —— 2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-cycloheptylacetamide —— C21H28N4OS
    2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-cycloheptylacetamide
    —— N-[(1S)-1-(4-chlorophenyl)ethyl]-2-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylsulfanyl)acetamide —— C19H20ClNO3S
    N-[(1S)-1-(4-chlorophenyl)ethyl]-2-(3,4-dihydro-2H-1,5-benzodioxepin-7-ylsulfanyl)acetamide
    —— 2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-(cyclohexylmethyl)acetamide —— C21H28N4OS
    2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-(cyclohexylmethyl)acetamide
    —— N-[(1S)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C15H19ClN4O2S2
    N-[(1S)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— N-[(1R)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C15H19ClN4O2S2
    N-[(1R)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-methoxyethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— (2S)-2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile —— C16H22N6S
    (2S)-2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile
    —— (2R)-2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile —— C16H22N6S
    (2R)-2-[(4-cyclopropyl-5-piperidin-1-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile
    —— 1-[4-(4-Chlorophenyl)sulfanylbutyl]piperazine-1,4-diium —— C14H23ClN2S+2
    1-[4-(4-Chlorophenyl)sulfanylbutyl]piperazine-1,4-diium
    —— methyl 5-[(2S)-2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C21H24N4O3S
    methyl 5-[(2S)-2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— 2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-cyano-1-cyclopropylethyl]acetamide —— C20H23N5OS
    2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-cyano-1-cyclopropylethyl]acetamide
    —— 2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2-chlorophenyl)methyl]acetamide —— C21H21ClN4OS
    2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2-chlorophenyl)methyl]acetamide
    —— 1-(6-ethylsulfanylpyridin-3-yl)-3-[(1R)-1-(1,3,5-trimethylpyrazol-4-yl)ethyl]urea —— C16H23N5OS
    1-(6-ethylsulfanylpyridin-3-yl)-3-[(1R)-1-(1,3,5-trimethylpyrazol-4-yl)ethyl]urea
    —— 1-[2-[(4-Benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]imidazolidin-2-one —— C17H19N5O2S
    1-[2-[(4-Benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]imidazolidin-2-one
    —— 2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamide —— C20H21ClN4OS
    2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamide
    —— (2S)-N-[5-chloro-2-(1-methyltetrazol-5-yl)sulfanylphenyl]-2-ethoxypropanamide —— C13H16ClN5O2S
    (2S)-N-[5-chloro-2-(1-methyltetrazol-5-yl)sulfanylphenyl]-2-ethoxypropanamide
    —— 7-[(4-Benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-3-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one —— C18H17N5OS2
    7-[(4-Benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-3-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one
    —— 3-Pyrimidin-2-ylsulfanylpropyl(thiophen-2-ylmethyl)azanium —— C12H16N3S2+
    3-Pyrimidin-2-ylsulfanylpropyl(thiophen-2-ylmethyl)azanium
    —— 2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(3-chlorophenyl)ethyl]acetamide —— C20H21ClN4OS
    2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-(3-chlorophenyl)ethyl]acetamide
    —— 2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(4-fluorophenyl)ethyl]acetamide —— C20H21FN4OS
    2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-(4-fluorophenyl)ethyl]acetamide
    —— 2-(2,3,4-Trichlorophenyl)sulfanylacetate —— C8H4Cl3O2S-
    2-(2,3,4-Trichlorophenyl)sulfanylacetate
    —— 2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1-cyanocyclopentyl)acetamide —— C18H21N5OS
    2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1-cyanocyclopentyl)acetamide
    —— N-[(1R)-1-(1-adamantyl)ethyl]-2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C24H32N4OS
    N-[(1R)-1-(1-adamantyl)ethyl]-2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— [5-(4-Fluorophenyl)furan-2-yl]methyl-(3-pyrimidin-2-ylsulfanylpropyl)azanium —— C18H19FN3OS+
    [5-(4-Fluorophenyl)furan-2-yl]methyl-(3-pyrimidin-2-ylsulfanylpropyl)azanium
    —— 1-[4-(4-Methylphenyl)sulfanylbutyl]piperazine-1,4-diium —— C15H26N2S+2
    1-[4-(4-Methylphenyl)sulfanylbutyl]piperazine-1,4-diium
    —— (2R)-N-[5-chloro-2-(1-methyltetrazol-5-yl)sulfanylphenyl]-2-ethoxypropanamide —— C13H16ClN5O2S
    (2R)-N-[5-chloro-2-(1-methyltetrazol-5-yl)sulfanylphenyl]-2-ethoxypropanamide
    —— 2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-cyano-1-cyclopropylethyl]acetamide —— C20H23N5OS
    2-[(4-benzyl-5-cyclopropyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-cyano-1-cyclopropylethyl]acetamide
    —— (2R)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile —— C15H20N6OS
    (2R)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile
    —— (2S)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile —— C15H20N6OS
    (2S)-2-[(4-cyclopropyl-5-morpholin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pentanedinitrile
    —— (2S)-3-methyl-2-phenylsulfanyl-N-(2-sulfamoylethyl)butanamide —— C13H20N2O3S2
    (2S)-3-methyl-2-phenylsulfanyl-N-(2-sulfamoylethyl)butanamide