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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C16H23NO3S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-(1-adamantylmethyl)-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C23H33NOS
    N-(1-adamantylmethyl)-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C16H23NO3S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— 1-[2,5-dimethyl-1-[[(2S)-oxolan-2-yl]methyl]pyrrol-3-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylethanone —— C23H31NO2S
    1-[2,5-dimethyl-1-[[(2S)-oxolan-2-yl]methyl]pyrrol-3-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylethanone
    —— Methyl 3-[2,5-dimethyl-3-[2-(2,3,5,6-tetramethylphenyl)sulfanylacetyl]pyrrol-1-yl]propanoate —— C22H29NO3S
    Methyl 3-[2,5-dimethyl-3-[2-(2,3,5,6-tetramethylphenyl)sulfanylacetyl]pyrrol-1-yl]propanoate
    —— N-[(2R)-3-methylbutan-2-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C17H27NOS
    N-[(2R)-3-methylbutan-2-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-[(3-chlorophenyl)methyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C19H22ClNOS
    N-[(3-chlorophenyl)methyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-1-phenylsulfanylcyclopentane-1-carboxamide —— C16H21NO3S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-1-phenylsulfanylcyclopentane-1-carboxamide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-1-phenylsulfanylcyclopentane-1-carboxamide —— C16H21NO3S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-1-phenylsulfanylcyclopentane-1-carboxamide
    —— N-[(2R)-2-phenylpropyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C21H27NOS
    N-[(2R)-2-phenylpropyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-[(2S)-3-methylbutan-2-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C17H27NOS
    N-[(2S)-3-methylbutan-2-yl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— (2R)-N-benzyl-2-(2,3,5,6-tetramethylphenyl)sulfanylpropanamide —— C20H25NOS
    (2R)-N-benzyl-2-(2,3,5,6-tetramethylphenyl)sulfanylpropanamide
    —— N-[(1R)-1-(1-adamantyl)ethyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C24H35NOS
    N-[(1R)-1-(1-adamantyl)ethyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-(1-cyanocyclohexyl)-N-methyl-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C20H28N2OS
    N-(1-cyanocyclohexyl)-N-methyl-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-[2-(4-chlorophenyl)ethyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C20H24ClNOS
    N-[2-(4-chlorophenyl)ethyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-(2-phenylsulfanylphenyl)-2-(2,3,5,6-tetrafluorophenoxy)acetamide —— C20H13F4NO2S
    N-(2-phenylsulfanylphenyl)-2-(2,3,5,6-tetrafluorophenoxy)acetamide
    —— ethyl N-[5-[(2S)-1-oxo-1-(2-propanoylhydrazinyl)propan-2-yl]sulfanyl-1,3,4-thiadiazol-2-yl]carbamate —— C11H17N5O4S2
    ethyl N-[5-[(2S)-1-oxo-1-(2-propanoylhydrazinyl)propan-2-yl]sulfanyl-1,3,4-thiadiazol-2-yl]carbamate
    —— ethyl N-[5-[(2R)-1-oxo-1-(2-propanoylhydrazinyl)propan-2-yl]sulfanyl-1,3,4-thiadiazol-2-yl]carbamate —— C11H17N5O4S2
    ethyl N-[5-[(2R)-1-oxo-1-(2-propanoylhydrazinyl)propan-2-yl]sulfanyl-1,3,4-thiadiazol-2-yl]carbamate
    —— (1R)-1-(2-fluorophenyl)-2-[(4-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethanol —— C13H16FN3OS
    (1R)-1-(2-fluorophenyl)-2-[(4-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethanol
    —— (1S)-1-(2-fluorophenyl)-2-[(4-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethanol —— C13H16FN3OS
    (1S)-1-(2-fluorophenyl)-2-[(4-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethanol
    —— N-(1-cyanocyclopentyl)-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide —— C14H11F5N2OS
    N-(1-cyanocyclopentyl)-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide
    —— N-[(1R)-1-(1-adamantyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide —— C20H22F5NOS
    N-[(1R)-1-(1-adamantyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide
    —— N-[(1S)-1-(3-chlorophenyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide —— C16H11ClF5NOS
    N-[(1S)-1-(3-chlorophenyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide
    —— 6-Amino-5-[2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetyl]-1-propylpyrimidine-2,4-dione —— C15H12F5N3O3S
    6-Amino-5-[2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetyl]-1-propylpyrimidine-2,4-dione
    —— 2-(2,3,4,5,6-pentafluorophenyl)sulfanyl-1-(1H-pyrrol-2-yl)ethanone —— C12H6F5NOS
    2-(2,3,4,5,6-pentafluorophenyl)sulfanyl-1-(1H-pyrrol-2-yl)ethanone
    —— 7-[(2,3,4,5,6-Pentafluorophenyl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one —— C13H5F5N2OS2
    7-[(2,3,4,5,6-Pentafluorophenyl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
    —— N-[(1R)-1-(3-chlorophenyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide —— C16H11ClF5NOS
    N-[(1R)-1-(3-chlorophenyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide
    —— (2R)-2-(2,3,4,5,6-pentafluorophenyl)sulfanylpropanamide —— C9H6F5NOS
    (2R)-2-(2,3,4,5,6-pentafluorophenyl)sulfanylpropanamide
    —— 2-(2,3,4,5,6-pentafluorophenyl)sulfanyl-N-(2-phenylethyl)acetamide —— C16H12F5NOS
    2-(2,3,4,5,6-pentafluorophenyl)sulfanyl-N-(2-phenylethyl)acetamide
    —— N-[(1S)-1-(1-adamantyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide —— C20H22F5NOS
    N-[(1S)-1-(1-adamantyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide
    —— N-[(4-fluorophenyl)methyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide —— C15H9F6NOS
    N-[(4-fluorophenyl)methyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide
    —— N'-[(2R)-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-3-methylbutanehydrazide —— C13H21N5O2S2
    N'-[(2R)-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-3-methylbutanehydrazide
    —— N-[2-(4-chlorophenyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide —— C16H11ClF5NOS
    N-[2-(4-chlorophenyl)ethyl]-2-(2,3,4,5,6-pentafluorophenyl)sulfanylacetamide
    —— N'-[(2S)-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-3-methylbutanehydrazide —— C13H21N5O2S2
    N'-[(2S)-2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]propanoyl]-3-methylbutanehydrazide
    —— 5-[2-(2-chlorophenyl)ethylsulfanyl]-1-[[(2R)-oxolan-2-yl]methyl]tetrazole —— C14H17ClN4OS
    5-[2-(2-chlorophenyl)ethylsulfanyl]-1-[[(2R)-oxolan-2-yl]methyl]tetrazole
    —— 2-(cyclohexylmethylsulfonyl)-N-[(1R,2R,3S)-2,3-dimethylcyclohexyl]acetamide —— C17H31NO3S
    2-(cyclohexylmethylsulfonyl)-N-[(1R,2R,3S)-2,3-dimethylcyclohexyl]acetamide
    —— 2-(cyclohexylmethylsulfonyl)-N-[(1S,2R,3R)-2,3-dimethylcyclohexyl]acetamide —— C17H31NO3S
    2-(cyclohexylmethylsulfonyl)-N-[(1S,2R,3R)-2,3-dimethylcyclohexyl]acetamide
    —— 4-methyl-2-[(1R)-1-pyridin-4-ylethyl]sulfanyl-1,3-thiazole —— C11H12N2S2
    4-methyl-2-[(1R)-1-pyridin-4-ylethyl]sulfanyl-1,3-thiazole
    —— N-[(1S,2R)-2-benzylcyclohexyl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)acetamide —— C17H22N4OS
    N-[(1S,2R)-2-benzylcyclohexyl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)acetamide
    —— N-[(1S,2S)-2-benzylcyclohexyl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)acetamide —— C17H22N4OS
    N-[(1S,2S)-2-benzylcyclohexyl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)acetamide
    —— N-[(1R,2R)-2-benzylcyclohexyl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)acetamide —— C17H22N4OS
    N-[(1R,2R)-2-benzylcyclohexyl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)acetamide
    —— N'-[(2S)-2-[(5-tert-butyl-1,3,4-oxadiazol-2-yl)sulfanyl]propanoyl]-3-methylbutanehydrazide —— C14H24N4O3S
    N'-[(2S)-2-[(5-tert-butyl-1,3,4-oxadiazol-2-yl)sulfanyl]propanoyl]-3-methylbutanehydrazide
    —— N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[[6-oxo-4-(trifluoromethyl)-1H-pyrimidin-2-yl]sulfanyl]acetamide —— C13H15F3N4O2S
    N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[[6-oxo-4-(trifluoromethyl)-1H-pyrimidin-2-yl]sulfanyl]acetamide
    —— N-[(2R)-2-cyano-3-methylbutan-2-yl]-2-[[6-oxo-4-(trifluoromethyl)-1H-pyrimidin-2-yl]sulfanyl]acetamide —— C13H15F3N4O2S
    N-[(2R)-2-cyano-3-methylbutan-2-yl]-2-[[6-oxo-4-(trifluoromethyl)-1H-pyrimidin-2-yl]sulfanyl]acetamide
    —— 3-(2,5-dioxopyrrolidin-1-yl)-N-[(1S)-1-(4-propan-2-ylsulfanylphenyl)ethyl]propanamide —— C18H24N2O3S
    3-(2,5-dioxopyrrolidin-1-yl)-N-[(1S)-1-(4-propan-2-ylsulfanylphenyl)ethyl]propanamide
    —— 3-(2,5-dioxopyrrolidin-1-yl)-N-[(1R)-1-(4-propan-2-ylsulfanylphenyl)ethyl]propanamide —— C18H24N2O3S
    3-(2,5-dioxopyrrolidin-1-yl)-N-[(1R)-1-(4-propan-2-ylsulfanylphenyl)ethyl]propanamide
    —— N-[(1S)-1-cyano-3-methylbutyl]-3-cyclopentylsulfonylpropanamide —— C14H24N2O3S
    N-[(1S)-1-cyano-3-methylbutyl]-3-cyclopentylsulfonylpropanamide
    —— N-[(1R)-1-cyano-3-methylbutyl]-3-cyclopentylsulfonylpropanamide —— C14H24N2O3S
    N-[(1R)-1-cyano-3-methylbutyl]-3-cyclopentylsulfonylpropanamide
    —— (2S)-N-(2-cyanoethyl)-N-(2-morpholin-4-ylethyl)-2,3-dihydro-1-benzothiophene-2-carboxamide —— C18H23N3O2S
    (2S)-N-(2-cyanoethyl)-N-(2-morpholin-4-ylethyl)-2,3-dihydro-1-benzothiophene-2-carboxamide
    —— (2R)-N-(2-cyanoethyl)-N-(2-morpholin-4-ylethyl)-2,3-dihydro-1-benzothiophene-2-carboxamide —— C18H23N3O2S
    (2R)-N-(2-cyanoethyl)-N-(2-morpholin-4-ylethyl)-2,3-dihydro-1-benzothiophene-2-carboxamide