有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在,在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特,在药物设计、合成化学以及材料制备方面扮演着重要角色。
1. 结构与分类有机硫化合物可以按硫的连接方式分为饱和和不饱和类,如二硫化物、噻吩衍生物、砜等。常见的结构类型有:
许多有机硫化合物在生物学上有重要功能或应用潜力。例如:
有机硫化合物可通过多种途径合成:
有机硫化合物的应用广泛:
尽管有机硫化合物具有许多潜在益处,但其生产和使用也可能对环境造成影响。因此,在设计和合成这些化合物时需要考虑可持续性和环保性因素。
以上是对有机硫化合物的简单介绍,包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。
中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
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—— | (4S)-3-acetyl-2-methyl-6-(phenylsulfanylmethylsulfanyl)-4-thiophen-2-yl-3,4-dihydropyridine-5-carbonitrile | —— | C20H18N2OS3 |
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—— | (4R)-3-acetyl-2-methyl-6-(phenylsulfanylmethylsulfanyl)-4-pyridin-3-yl-3,4-dihydropyridine-5-carbonitrile | —— | C21H19N3OS2 |
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—— | 2-(2,4-dimethylphenyl)sulfanyl-N-[2-(4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)ethyl]acetamide | —— | C15H18N2O2S3 |
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—— | 2-(2,4-dimethylphenyl)sulfanyl-N-(furan-2-ylmethyl)acetamide | —— | C15H17NO2S |
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—— | (4S)-5-acetyl-4-(4-ethylphenyl)-6-methyl-2-(phenylsulfanylmethylsulfanyl)-3,4-dihydropyridine-3-carbonitrile | —— | C24H24N2OS2 |
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—— | 2-(2,4-dimethylphenyl)sulfanyl-N-[(1S)-1-(4-fluorophenyl)ethyl]acetamide | —— | C18H20FNOS |
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—— | N-[[(3S,8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-yl]methyl]-2-(4-chlorophenyl)sulfanylacetamide | —— | C16H21ClN2O2S |
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—— | 2-(2,4-dimethylphenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]-N-methylacetamide | —— | C15H21NO3S2 |
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—— | 2-(2,4-dimethylphenyl)sulfanyl-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylacetamide | —— | C15H21NO3S2 |
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—— | 2-(2,4-dimethylphenyl)sulfanyl-N-(thiophen-2-ylmethyl)acetamide | —— | C15H17NOS2 |
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—— | N-cyclohexyl-2-(2,5-dimethylphenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]acetamide | —— | C20H29NO3S2 |
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—— | N-(1-cyanocyclohexyl)-2-(2,5-dimethylphenyl)sulfanyl-N-methylacetamide | —— | C18H24N2OS |
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—— | 6-Amino-5-[2-(2,5-dimethylphenyl)sulfanylacetyl]-1-propylpyrimidine-2,4-dione | —— | C17H21N3O3S |
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—— | N-(1-cyanocyclohexyl)-2-(2,5-dimethylphenyl)sulfanylacetamide | —— | C17H22N2OS |
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—— | N-(1-cyanocyclopentyl)-2-(2,5-dimethylphenyl)sulfanylacetamide | —— | C16H20N2OS |
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—— | 2-(2,5-dimethylphenyl)sulfanyl-N-(4-methylcyclohexyl)acetamide | —— | C17H25NOS |
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—— | 2-(2,5-dimethylphenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]-N-methylacetamide | —— | C15H21NO3S2 |
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—— | 2-(2,5-dimethylphenyl)sulfanyl-N-[(1S)-1-thiophen-2-ylethyl]acetamide | —— | C16H19NOS2 |
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—— | (2S)-2-(2,5-dimethylphenyl)sulfanyl-N-(furan-2-ylmethyl)propanamide | —— | C16H19NO2S |
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—— | N-[(3-chlorophenyl)methyl]-2-(2,5-dimethylphenyl)sulfanylacetamide | —— | C17H18ClNOS |
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—— | 1-(5-phenyl-3,4-dihydropyrazol-2-yl)-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]ethanone | —— | C17H15N5OS2 |
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—— | N-methyl-N-[(4-methylphenyl)methyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C17H18N4OS2 |
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—— | N-[(1R)-1-phenylethyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C16H16N4OS2 |
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—— | N-(2-phenylethyl)-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C16H16N4OS2 |
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—— | 3-[(2-bromophenyl)methylsulfanyl]-5-thiophen-2-yl-1H-1,2,4-triazole | —— | C13H10BrN3S2 |
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—— | 1-[(2R)-butan-2-yl]-3-(6-ethylsulfanylpyridin-3-yl)urea | —— | C12H19N3OS |
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—— | N-[(1S)-1-phenylethyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C16H16N4OS2 |
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—— | (2S)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | —— | C17H17FN4OS2 |
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—— | (3S)-3-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]oxolan-2-one | —— | C10H9N3O2S2 |
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—— | (2S)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | —— | C17H17FN4OS2 |
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—— | (2R)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | —— | C17H17FN4OS2 |
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—— | N-[(2S)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C16H22N4O3S3 |
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—— | 3-methyl-7-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one | —— | C14H11N5OS3 |
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—— | 3-benzylsulfanyl-5-thiophen-2-yl-1H-1,2,4-triazole | —— | C13H11N3S2 |
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—— | N-(4-methylcyclohexyl)-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C15H20N4OS2 |
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—— | 3-(2-methylsulfanylethylsulfanyl)-5-thiophen-2-yl-1H-1,2,4-triazole | —— | C9H11N3S3 |
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—— | 1-(6-ethylsulfanylpyridin-3-yl)-3-[(1R)-1-(5-methylfuran-2-yl)ethyl]urea | —— | C15H19N3O2S |
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—— | N-[(2S)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C16H22N4O3S3 |
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—— | 1-[(2S)-2-(dimethylamino)-2-thiophen-2-ylethyl]-3-(6-ethylsulfanylpyridin-3-yl)urea | —— | C16H22N4OS2 |
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—— | (2S)-N-[2-(cyclohexen-1-yl)ethyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | —— | C17H22N4OS2 |
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—— | (2S)-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | —— | C9H10N4OS2 |
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—— | N-[(2R)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C16H22N4O3S3 |
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—— | (2R)-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | —— | C9H10N4OS2 |
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—— | N-[(3R)-1-methyl-5-oxopyrrolidin-3-yl]-2-phenylsulfanylpyridine-3-carboxamide | —— | C17H17N3O2S |
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—— | (2R)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propanamide | —— | C17H17FN4OS2 |
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—— | N-[(3S)-1-methyl-5-oxopyrrolidin-3-yl]-2-phenylsulfanylpyridine-3-carboxamide | —— | C17H17N3O2S |
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—— | 1-[2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetyl]pyrrolidin-2-one | —— | C12H12N4O2S2 |
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—— | N-(2-cyanoethyl)-N-methyl-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C12H13N5OS2 |
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—— | 1-(6-ethylsulfanylpyridin-3-yl)-3-[(1S)-1-(5-methylfuran-2-yl)ethyl]urea | —— | C15H19N3O2S |
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—— | (2S)-1-pyrrolidin-1-yl-2-[(5-thiophen-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]propan-1-one | —— | C13H16N4OS2 |
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