摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2R)-2-[(4,5-dimethyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]propanoate —— C9H11N2O3S-
    (2R)-2-[(4,5-dimethyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]propanoate
    —— methyl (3R)-3-(4-methylsulfanylphenyl)-3-(pyridin-2-ylcarbamoylamino)propanoate —— C17H19N3O3S
    methyl (3R)-3-(4-methylsulfanylphenyl)-3-(pyridin-2-ylcarbamoylamino)propanoate
    —— 2-(4-methyl-6-oxo-2-propan-2-ylsulfanyl-1H-pyrimidin-5-yl)acetate —— C10H13N2O3S-
    2-(4-methyl-6-oxo-2-propan-2-ylsulfanyl-1H-pyrimidin-5-yl)acetate
    —— methyl (3S)-3-(4-methylsulfanylphenyl)-3-(pyridin-2-ylcarbamoylamino)propanoate —— C17H19N3O3S
    methyl (3S)-3-(4-methylsulfanylphenyl)-3-(pyridin-2-ylcarbamoylamino)propanoate
    —— N-[(2S)-2-(dimethylamino)-2-phenylethyl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide —— C18H20F3N3OS
    N-[(2S)-2-(dimethylamino)-2-phenylethyl]-2-[5-(trifluoromethyl)pyridin-2-yl]sulfanylacetamide
    —— N-[(1S)-1-[4-(2-methoxyethylsulfanyl)phenyl]ethyl]tetrazolo[1,5-b]pyridazin-6-amine —— C15H18N6OS
    N-[(1S)-1-[4-(2-methoxyethylsulfanyl)phenyl]ethyl]tetrazolo[1,5-b]pyridazin-6-amine
    —— 5-[[(2S)-oxan-2-yl]methylsulfanyl]-1-(2,2,2-trifluoroethyl)tetrazole —— C9H13F3N4OS
    5-[[(2S)-oxan-2-yl]methylsulfanyl]-1-(2,2,2-trifluoroethyl)tetrazole
    —— 1-cyclopropyl-2-[[(2S)-oxan-2-yl]methylsulfanyl]pyrimidin-4-one —— C13H18N2O2S
    1-cyclopropyl-2-[[(2S)-oxan-2-yl]methylsulfanyl]pyrimidin-4-one
    —— (2R)-N-cyclohexyl-2-(4-oxo-1-propan-2-ylpyrimidin-2-yl)sulfanylpropanamide —— C16H25N3O2S
    (2R)-N-cyclohexyl-2-(4-oxo-1-propan-2-ylpyrimidin-2-yl)sulfanylpropanamide
    —— 5-[[(2R)-oxan-2-yl]methylsulfanyl]-1-(2,2,2-trifluoroethyl)tetrazole —— C9H13F3N4OS
    5-[[(2R)-oxan-2-yl]methylsulfanyl]-1-(2,2,2-trifluoroethyl)tetrazole
    —— (2S)-N-cyclohexyl-2-(4-oxo-1-propan-2-ylpyrimidin-2-yl)sulfanylpropanamide —— C16H25N3O2S
    (2S)-N-cyclohexyl-2-(4-oxo-1-propan-2-ylpyrimidin-2-yl)sulfanylpropanamide
    —— N-[(1R)-1-[4-(2-methoxyethylsulfanyl)phenyl]ethyl]tetrazolo[1,5-b]pyridazin-6-amine —— C15H18N6OS
    N-[(1R)-1-[4-(2-methoxyethylsulfanyl)phenyl]ethyl]tetrazolo[1,5-b]pyridazin-6-amine
    —— 1-cyclopropyl-2-[[(2R)-oxan-2-yl]methylsulfanyl]pyrimidin-4-one —— C13H18N2O2S
    1-cyclopropyl-2-[[(2R)-oxan-2-yl]methylsulfanyl]pyrimidin-4-one
    —— N-[(4-fluorophenyl)methyl]-2-[[5-oxo-4-(2-phenylethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C19H19FN4O2S
    N-[(4-fluorophenyl)methyl]-2-[[5-oxo-4-(2-phenylethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(2S)-1-methoxypropan-2-yl]acetamide —— C8H14N4O2S2
    2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(2S)-1-methoxypropan-2-yl]acetamide
    —— 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(2R)-1-methoxypropan-2-yl]acetamide —— C8H14N4O2S2
    2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(2R)-1-methoxypropan-2-yl]acetamide
    —— 2-[[5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(5-phenyl-3,4-dihydropyrazol-2-yl)ethanone —— C19H15FN4O2S
    2-[[5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-(5-phenyl-3,4-dihydropyrazol-2-yl)ethanone
    —— (2R)-N-[(2-ethyl-1,3-thiazol-4-yl)methyl]-N-methyl-2,3-dihydro-1,4-benzoxathiine-2-carboxamide —— C16H18N2O2S2
    (2R)-N-[(2-ethyl-1,3-thiazol-4-yl)methyl]-N-methyl-2,3-dihydro-1,4-benzoxathiine-2-carboxamide
    —— 4-[4-[[(2R)-oxolan-2-yl]methyl]-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl]morpholine —— C14H22N4O2S
    4-[4-[[(2R)-oxolan-2-yl]methyl]-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl]morpholine
    —— (2S)-N-[(2-ethyl-1,3-thiazol-4-yl)methyl]-N-methyl-2,3-dihydro-1,4-benzoxathiine-2-carboxamide —— C16H18N2O2S2
    (2S)-N-[(2-ethyl-1,3-thiazol-4-yl)methyl]-N-methyl-2,3-dihydro-1,4-benzoxathiine-2-carboxamide
    —— N-[(1R)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15ClFN3O2S
    N-[(1R)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone —— C16H18FN3O3S
    1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone
    —— 7-({[5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-YL]sulfanyl}methyl)-3-methyl-5H-[1,3]thiazolo[3,2-A]pyrimidin-5-one —— C16H11FN4O2S2
    7-({[5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-YL]sulfanyl}methyl)-3-methyl-5H-[1,3]thiazolo[3,2-A]pyrimidin-5-one
    —— 4-[4-[[(2S)-oxolan-2-yl]methyl]-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl]morpholine —— C14H22N4O2S
    4-[4-[[(2S)-oxolan-2-yl]methyl]-5-prop-2-enylsulfanyl-1,2,4-triazol-3-yl]morpholine
    —— 2-[(1S)-1-(2-chlorophenyl)ethyl]sulfanyl-5-(2-fluorophenyl)-1,3,4-oxadiazole —— C16H12ClFN2OS
    2-[(1S)-1-(2-chlorophenyl)ethyl]sulfanyl-5-(2-fluorophenyl)-1,3,4-oxadiazole
    —— 1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone —— C16H18FN3O3S
    1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4-methylphenyl)sulfanyl-N-propylacetamide —— C16H23NO3S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4-methylphenyl)sulfanyl-N-propylacetamide
    —— (2S)-N-cyclopropyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C14H14FN3O2S
    (2S)-N-cyclopropyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— N-[(1S)-1-(3-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15ClFN3O2S
    N-[(1S)-1-(3-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15ClFN3O2S
    N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— methyl 5-[(2S)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C19H18FN3O4S
    methyl 5-[(2S)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— (2R)-N-cyclohexyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C17H20FN3O2S
    (2R)-N-cyclohexyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— methyl 5-[(2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C19H18FN3O4S
    methyl 5-[(2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— (2S)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C11H10FN3O2S
    (2S)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— N-[(1S)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15ClFN3O2S
    N-[(1S)-1-(4-chlorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— (2R)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C19H17F2N3O2S
    (2R)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— (2S)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C19H17F2N3O2S
    (2S)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— 2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-methyl-N-[(2-methylphenyl)methyl]acetamide —— C19H18FN3O2S
    2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-methyl-N-[(2-methylphenyl)methyl]acetamide
    —— N-(cyclohexylmethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C17H20FN3O2S
    N-(cyclohexylmethyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-cyclopropyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C13H12FN3O2S
    N-cyclopropyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-(1-cyanocyclopentyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C16H15FN4O2S
    N-(1-cyanocyclopentyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— (2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C11H10FN3O2S
    (2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— (2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanenitrile —— C11H8FN3OS
    (2R)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanenitrile
    —— (2S)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C19H17F2N3O2S
    (2S)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— ethyl (2S)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-2-phenylacetate —— C18H15FN2O3S
    ethyl (2S)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-2-phenylacetate
    —— (2S)-N-cyclohexyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide —— C17H20FN3O2S
    (2S)-N-cyclohexyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]propanamide
    —— N-benzyl-N-ethyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C19H18FN3O2S
    N-benzyl-N-ethyl-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C14H14FN3O4S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 2-[(3,5-Dimethyl-1,2-oxazol-4-yl)methylsulfanyl]-5-(2-fluorophenyl)-1,3,4-oxadiazole —— C14H12FN3O2S
    2-[(3,5-Dimethyl-1,2-oxazol-4-yl)methylsulfanyl]-5-(2-fluorophenyl)-1,3,4-oxadiazole
    —— 2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[1-[(2S)-1-methoxypropan-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone —— C20H22FN3O3S
    2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[1-[(2S)-1-methoxypropan-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone