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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-(4-methylphenyl)-4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-1,3-thiazol-2-amine —— C14H15N5S2
    N-(4-methylphenyl)-4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-1,3-thiazol-2-amine
    —— [2-Oxo-2-(2-phenylsulfanylanilino)ethyl] 4-aminobenzoate —— C21H18N2O3S
    [2-Oxo-2-(2-phenylsulfanylanilino)ethyl] 4-aminobenzoate
    —— 2-(2-Fluorophenyl)sulfanylethyl 3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate —— C19H15ClFNO3S
    2-(2-Fluorophenyl)sulfanylethyl 3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate
    —— 2-(4-bromophenyl)sulfanyl-N-[(2S)-2-(furan-2-yl)-2-pyrrolidin-1-ylethyl]acetamide —— C18H21BrN2O2S
    2-(4-bromophenyl)sulfanyl-N-[(2S)-2-(furan-2-yl)-2-pyrrolidin-1-ylethyl]acetamide
    —— N-[(2R)-2-(furan-2-yl)-2-pyrrolidin-1-ium-1-ylethyl]-2-phenylsulfanylacetamide —— C18H23N2O2S+
    N-[(2R)-2-(furan-2-yl)-2-pyrrolidin-1-ium-1-ylethyl]-2-phenylsulfanylacetamide
    —— N-[(2R)-2-(furan-2-yl)-2-pyrrolidin-1-ylethyl]-2-phenylsulfanylacetamide —— C18H22N2O2S
    N-[(2R)-2-(furan-2-yl)-2-pyrrolidin-1-ylethyl]-2-phenylsulfanylacetamide
    —— N-[(2S)-2-(furan-2-yl)-2-pyrrolidin-1-ylethyl]-2-phenylsulfanylacetamide —— C18H22N2O2S
    N-[(2S)-2-(furan-2-yl)-2-pyrrolidin-1-ylethyl]-2-phenylsulfanylacetamide
    —— 1,2-Dimethyl-4-(4-methylsulfonyl-2-nitrophenyl)sulfanylbenzene —— C15H15NO4S2
    1,2-Dimethyl-4-(4-methylsulfonyl-2-nitrophenyl)sulfanylbenzene
    —— Tcmdc-142496 —— C15H16N4OS2
    Tcmdc-142496
    —— 4-Methylsulfonyl-2-nitro-1-[3-(trifluoromethyl)phenyl]sulfanylbenzene —— C14H10F3NO4S2
    4-Methylsulfonyl-2-nitro-1-[3-(trifluoromethyl)phenyl]sulfanylbenzene
    —— 5-[(5-methyl-1,2-oxazol-3-yl)methylsulfanyl]-N-(3-methylphenyl)-1,3,4-thiadiazol-2-amine —— C14H14N4OS2
    5-[(5-methyl-1,2-oxazol-3-yl)methylsulfanyl]-N-(3-methylphenyl)-1,3,4-thiadiazol-2-amine
    —— 2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-phenylsulfanylethyl)acetamide —— C19H20N4OS3
    2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-phenylsulfanylethyl)acetamide
    —— 1-(2-Chlorophenyl)sulfanyl-4-methylsulfonyl-2-nitrobenzene —— C13H10ClNO4S2
    1-(2-Chlorophenyl)sulfanyl-4-methylsulfonyl-2-nitrobenzene
    —— 5-[(5-methyl-1,2-oxazol-3-yl)methylsulfanyl]-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine —— C14H14N4OS2
    5-[(5-methyl-1,2-oxazol-3-yl)methylsulfanyl]-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine
    —— [2-oxo-2-(2-phenylsulfanylanilino)ethyl] (1R,2R)-2-methylcyclopropane-1-carboxylate —— C19H19NO3S
    [2-oxo-2-(2-phenylsulfanylanilino)ethyl] (1R,2R)-2-methylcyclopropane-1-carboxylate
    —— [2-[4-(2,5-dimethylphenyl)sulfanylanilino]-2-oxoethyl] (1S,2S)-2-methylcyclopropane-1-carboxylate —— C21H23NO3S
    [2-[4-(2,5-dimethylphenyl)sulfanylanilino]-2-oxoethyl] (1S,2S)-2-methylcyclopropane-1-carboxylate
    —— [2-oxo-2-(2-phenylsulfanylanilino)ethyl] (1S,2S)-2-methylcyclopropane-1-carboxylate —— C19H19NO3S
    [2-oxo-2-(2-phenylsulfanylanilino)ethyl] (1S,2S)-2-methylcyclopropane-1-carboxylate
    —— [2-[4-(2,5-dimethylphenyl)sulfanylanilino]-2-oxoethyl] (1R,2R)-2-methylcyclopropane-1-carboxylate —— C21H23NO3S
    [2-[4-(2,5-dimethylphenyl)sulfanylanilino]-2-oxoethyl] (1R,2R)-2-methylcyclopropane-1-carboxylate
    —— [2-[4-(2,5-dimethylphenyl)sulfanylanilino]-2-oxoethyl] (1R,2S)-2-methylcyclopropane-1-carboxylate —— C21H23NO3S
    [2-[4-(2,5-dimethylphenyl)sulfanylanilino]-2-oxoethyl] (1R,2S)-2-methylcyclopropane-1-carboxylate
    —— [2-[4-(2,5-Dimethylphenyl)sulfanylanilino]-2-oxoethyl] pyridine-2-carboxylate —— C22H20N2O3S
    [2-[4-(2,5-Dimethylphenyl)sulfanylanilino]-2-oxoethyl] pyridine-2-carboxylate
    —— 1-[4-(difluoromethylsulfanyl)phenyl]-3-[(Z)-[(5R)-3,3,5-trimethylcyclohexylidene]amino]thiourea —— C17H23F2N3S2
    1-[4-(difluoromethylsulfanyl)phenyl]-3-[(Z)-[(5R)-3,3,5-trimethylcyclohexylidene]amino]thiourea
    —— N-(3-nitro-5-phenylsulfanylphenyl)acetamide —— C14H12N2O3S
    N-(3-nitro-5-phenylsulfanylphenyl)acetamide
    —— 1-[2-(4-Chlorophenyl)sulfanylphenyl]-3-(3-morpholin-4-ium-4-ylpropyl)thiourea —— C20H25ClN3OS2+
    1-[2-(4-Chlorophenyl)sulfanylphenyl]-3-(3-morpholin-4-ium-4-ylpropyl)thiourea
    —— [2-[2-(4-Chlorophenyl)sulfanylanilino]-2-oxoethyl] 1-oxidopyridin-1-ium-2-carboxylate —— C20H15ClN2O4S
    [2-[2-(4-Chlorophenyl)sulfanylanilino]-2-oxoethyl] 1-oxidopyridin-1-ium-2-carboxylate
    —— [2-(2-Methoxyethylamino)-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C18H20N2O4S
    [2-(2-Methoxyethylamino)-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [(2S)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C20H22N2O3S
    [(2S)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [2-[(2S)-2-methylpiperidin-1-yl]-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C21H24N2O3S
    [2-[(2S)-2-methylpiperidin-1-yl]-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— (2-Oxo-2-piperidin-1-ylethyl) 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C19H19ClN2O3S
    (2-Oxo-2-piperidin-1-ylethyl) 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-Oxo-2-(2-oxopyrrolidin-1-yl)ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C19H18N2O4S
    [2-Oxo-2-(2-oxopyrrolidin-1-yl)ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [2-oxo-2-[[(1R)-1-thiophen-2-ylethyl]amino]ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C21H20N2O3S2
    [2-oxo-2-[[(1R)-1-thiophen-2-ylethyl]amino]ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [(3R)-2-oxooxolan-3-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C16H12ClNO4S
    [(3R)-2-oxooxolan-3-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [(2S)-1-(2-fluoroanilino)-1-oxopropan-2-yl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C22H19FN2O3S
    [(2S)-1-(2-fluoroanilino)-1-oxopropan-2-yl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [2-(Methylamino)-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C16H16N2O3S
    [2-(Methylamino)-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— (2-Amino-2-oxoethyl) 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C14H11ClN2O3S
    (2-Amino-2-oxoethyl) 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-(Cyclopentylamino)-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C19H19ClN2O3S
    [2-(Cyclopentylamino)-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-Oxo-2-(propylamino)ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C18H20N2O3S
    [2-Oxo-2-(propylamino)ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [2-(Butylamino)-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C18H19ClN2O3S
    [2-(Butylamino)-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-[(1-Cyanocyclopentyl)amino]-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C20H18ClN3O3S
    [2-[(1-Cyanocyclopentyl)amino]-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-[[(2S)-2-cyano-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C21H23N3O3S
    [2-[[(2S)-2-cyano-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [(2S)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C20H21ClN2O3S
    [(2S)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— Cyanomethyl 2-(4-chlorophenyl)sulfanylpyridine-3-carboxylate —— C14H9ClN2O2S
    Cyanomethyl 2-(4-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [(2R)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C19H19ClN2O3S
    [(2R)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— (5-Oxo-[1,3]thiazolo[3,2-a]pyrimidin-7-yl)methyl 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C20H15N3O3S2
    (5-Oxo-[1,3]thiazolo[3,2-a]pyrimidin-7-yl)methyl 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [(1S)-1-cyanoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C15H11ClN2O2S
    [(1S)-1-cyanoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [(2R)-1-(2-fluoroanilino)-1-oxopropan-2-yl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C22H19FN2O3S
    [(2R)-1-(2-fluoroanilino)-1-oxopropan-2-yl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [2-[[(2S)-butan-2-yl]amino]-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C18H19ClN2O3S
    [2-[[(2S)-butan-2-yl]amino]-2-oxoethyl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-Oxo-2-(2,2,2-trifluoroethylamino)ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C17H15F3N2O3S
    [2-Oxo-2-(2,2,2-trifluoroethylamino)ethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate
    —— [(2S)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate —— C19H19ClN2O3S
    [(2S)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl] 2-(2-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-(Methylamino)-2-oxoethyl] 2-(4-chlorophenyl)sulfanylpyridine-3-carboxylate —— C15H13ClN2O3S
    [2-(Methylamino)-2-oxoethyl] 2-(4-chlorophenyl)sulfanylpyridine-3-carboxylate
    —— [2-[[(2S)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate —— C20H24N2O3S
    [2-[[(2S)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(4-methylphenyl)sulfanylpyridine-3-carboxylate