摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[(2S)-1-[(3S)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-1-oxopropan-2-yl]sulfanylpyridine-4-carbonitrile —— C22H17ClN4O2S
    2-[(2S)-1-[(3S)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-1-oxopropan-2-yl]sulfanylpyridine-4-carbonitrile
    —— 2-[2-[(3R)-3,5-dithiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanylpyridine-4-carbonitrile —— C19H14N4OS3
    2-[2-[(3R)-3,5-dithiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanylpyridine-4-carbonitrile
    —— 3-(3-methoxypropylsulfanyl)-4-[[(2R)-oxolan-2-yl]methyl]-1H-1,2,4-triazol-5-one —— C11H19N3O3S
    3-(3-methoxypropylsulfanyl)-4-[[(2R)-oxolan-2-yl]methyl]-1H-1,2,4-triazol-5-one
    —— N-[(1R)-1-cyano-1-cyclopropylethyl]-2-(4-cyanopyridin-2-yl)sulfanylacetamide —— C14H14N4OS
    N-[(1R)-1-cyano-1-cyclopropylethyl]-2-(4-cyanopyridin-2-yl)sulfanylacetamide
    —— 1-[2-(4-chlorophenyl)sulfanylethyl]-3-[(3R)-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butyl]urea —— C17H20ClF3N4O2S
    1-[2-(4-chlorophenyl)sulfanylethyl]-3-[(3R)-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butyl]urea
    —— 1-[2-(4-chlorophenyl)sulfanylethyl]-3-[(3S)-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butyl]urea —— C17H20ClF3N4O2S
    1-[2-(4-chlorophenyl)sulfanylethyl]-3-[(3S)-4,4,4-trifluoro-3-hydroxy-3-(1-methylimidazol-2-yl)butyl]urea
    —— N-[(1R)-2-methyl-1-(5-methyl-1H-1,2,4-triazol-3-yl)propyl]-2-(2-methylphenyl)sulfanylacetamide —— C16H22N4OS
    N-[(1R)-2-methyl-1-(5-methyl-1H-1,2,4-triazol-3-yl)propyl]-2-(2-methylphenyl)sulfanylacetamide
    —— N-[(1S)-2-methyl-1-(5-methyl-1H-1,2,4-triazol-3-yl)propyl]-2-(2-methylphenyl)sulfanylacetamide —— C16H22N4OS
    N-[(1S)-2-methyl-1-(5-methyl-1H-1,2,4-triazol-3-yl)propyl]-2-(2-methylphenyl)sulfanylacetamide
    —— (5R)-3-(2,6-difluorophenyl)-5-[(5-ethyl-1H-1,2,4-triazol-3-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole —— C14H14F2N4OS
    (5R)-3-(2,6-difluorophenyl)-5-[(5-ethyl-1H-1,2,4-triazol-3-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole
    —— (5R)-3-(2,6-difluorophenyl)-5-[(1-methyltetrazol-5-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole —— C12H11F2N5OS
    (5R)-3-(2,6-difluorophenyl)-5-[(1-methyltetrazol-5-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole
    —— (5S)-3-(2,6-difluorophenyl)-5-[(5-ethyl-1H-1,2,4-triazol-3-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole —— C14H14F2N4OS
    (5S)-3-(2,6-difluorophenyl)-5-[(5-ethyl-1H-1,2,4-triazol-3-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole
    —— 2-[[5-(4-methoxyanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-phenylsulfanylphenyl)acetamide —— C23H20N4O2S3
    2-[[5-(4-methoxyanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-phenylsulfanylphenyl)acetamide
    —— (5S)-3-(2,6-difluorophenyl)-5-[(1-methyltetrazol-5-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole —— C12H11F2N5OS
    (5S)-3-(2,6-difluorophenyl)-5-[(1-methyltetrazol-5-yl)sulfanylmethyl]-4,5-dihydro-1,2-oxazole
    —— 1-[(2R)-2-[4-(2-methylpropyl)-1,2,4-triazol-3-yl]pyrrolidin-1-yl]-2-phenylsulfanylethanone —— C18H24N4OS
    1-[(2R)-2-[4-(2-methylpropyl)-1,2,4-triazol-3-yl]pyrrolidin-1-yl]-2-phenylsulfanylethanone
    —— 1-[(2S)-2-[4-(2-methylpropyl)-1,2,4-triazol-3-yl]pyrrolidin-1-yl]-2-phenylsulfanylethanone —— C18H24N4OS
    1-[(2S)-2-[4-(2-methylpropyl)-1,2,4-triazol-3-yl]pyrrolidin-1-yl]-2-phenylsulfanylethanone
    —— 6-[(1R)-1-thiophen-2-ylethyl]sulfanyltetrazolo[1,5-b]pyridazine —— C10H9N5S2
    6-[(1R)-1-thiophen-2-ylethyl]sulfanyltetrazolo[1,5-b]pyridazine
    —— 2-[2-[3-[(2S)-butan-2-yl]sulfanyl-1,2,4-triazol-4-yl]ethyl]pyridine —— C13H18N4S
    2-[2-[3-[(2S)-butan-2-yl]sulfanyl-1,2,4-triazol-4-yl]ethyl]pyridine
    —— 6-[(1S)-1-thiophen-2-ylethyl]sulfanyltetrazolo[1,5-b]pyridazine —— C10H9N5S2
    6-[(1S)-1-thiophen-2-ylethyl]sulfanyltetrazolo[1,5-b]pyridazine
    —— 2-[2-[3-[(2R)-butan-2-yl]sulfanyl-1,2,4-triazol-4-yl]ethyl]pyridine —— C13H18N4S
    2-[2-[3-[(2R)-butan-2-yl]sulfanyl-1,2,4-triazol-4-yl]ethyl]pyridine
    —— 2-[5-[(2S)-butan-2-yl]sulfanyltetrazol-1-yl]-N,N-dimethylethanamine —— C9H19N5S
    2-[5-[(2S)-butan-2-yl]sulfanyltetrazol-1-yl]-N,N-dimethylethanamine
    —— 4-[(1-cyclopentyltetrazol-5-yl)sulfanylmethyl]-2-[(1S)-1-ethoxyethyl]-1,3-thiazole —— C14H21N5OS2
    4-[(1-cyclopentyltetrazol-5-yl)sulfanylmethyl]-2-[(1S)-1-ethoxyethyl]-1,3-thiazole
    —— 2-[5-[(2R)-butan-2-yl]sulfanyltetrazol-1-yl]-N,N-dimethylethanamine —— C9H19N5S
    2-[5-[(2R)-butan-2-yl]sulfanyltetrazol-1-yl]-N,N-dimethylethanamine
    —— 3-[(1R)-1-ethoxyethyl]-5-[(5-pyrrolidin-1-yl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-1,2,4-oxadiazole —— C13H19N5O2S2
    3-[(1R)-1-ethoxyethyl]-5-[(5-pyrrolidin-1-yl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-1,2,4-oxadiazole
    —— (2R)-2-(3-bromopyridin-2-yl)sulfanyl-N-(2,2,2-trifluoroethyl)propanamide —— C10H10BrF3N2OS
    (2R)-2-(3-bromopyridin-2-yl)sulfanyl-N-(2,2,2-trifluoroethyl)propanamide
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide —— C14H16N4O4S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide
    —— N-(1-adamantylmethyl)-2-[[5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C24H31N3O2S
    N-(1-adamantylmethyl)-2-[[5-[(2R)-2-phenylpropyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-[(1S,2R)-2-methylcyclohexyl]-2-(1-oxidopyridin-1-ium-2-yl)sulfanylacetamide —— C14H20N2O2S
    N-[(1S,2R)-2-methylcyclohexyl]-2-(1-oxidopyridin-1-ium-2-yl)sulfanylacetamide
    —— (2S)-2-(3-bromopyridin-2-yl)sulfanyl-N-(2,2,2-trifluoroethyl)propanamide —— C10H10BrF3N2OS
    (2S)-2-(3-bromopyridin-2-yl)sulfanyl-N-(2,2,2-trifluoroethyl)propanamide
    —— 2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]-1-[(1R,5S)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone —— C19H24N4O2S
    2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]-1-[(1R,5S)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone
    —— 2-[(3-Bromophenyl)methylsulfanyl]-5-(4-chlorophenyl)-1,3,4-oxadiazole —— C15H10BrClN2OS
    2-[(3-Bromophenyl)methylsulfanyl]-5-(4-chlorophenyl)-1,3,4-oxadiazole
    —— 3-Methyl-7-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one —— C15H11N5O2S2
    3-Methyl-7-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
    —— N-[(1S)-1-(1-adamantyl)ethyl]-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide —— C21H26N4O2S
    N-[(1S)-1-(1-adamantyl)ethyl]-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide
    —— 2-(4-Chlorophenyl)-5-[(4-methylsulfanylphenyl)methylsulfanyl]-1,3,4-oxadiazole —— C16H13ClN2OS2
    2-(4-Chlorophenyl)-5-[(4-methylsulfanylphenyl)methylsulfanyl]-1,3,4-oxadiazole
    —— N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15Cl2N3O2S
    N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[(1R,5S)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone —— C20H24ClN3O2S
    2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[(1R,5S)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide —— C14H16N4O4S2
    N-[(3R)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide
    —— (2R)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]cyclohexan-1-one —— C14H13ClN2O2S
    (2R)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]cyclohexan-1-one
    —— 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[(1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone —— C20H24ClN3O2S
    2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[(1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone
    —— N-[(1S)-1-(4-chlorophenyl)ethyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15Cl2N3O2S
    N-[(1S)-1-(4-chlorophenyl)ethyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2S)-2-phenylpropyl]acetamide —— C19H18ClN3O2S
    2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2S)-2-phenylpropyl]acetamide
    —— 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[1-[(2S)-1-methoxypropan-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone —— C20H22ClN3O3S
    2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[1-[(2S)-1-methoxypropan-2-yl]-2,5-dimethylpyrrol-3-yl]ethanone
    —— N-[(4-chlorophenyl)methyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C17H13Cl2N3O2S
    N-[(4-chlorophenyl)methyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— (2S)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]cyclohexan-1-one —— C14H13ClN2O2S
    (2S)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]cyclohexan-1-one
    —— 2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-5-(4-chlorophenyl)-1,3,4-oxadiazole —— C15H9Cl2FN2OS
    2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-5-(4-chlorophenyl)-1,3,4-oxadiazole
    —— N-[(1R)-1-(4-chlorophenyl)ethyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C18H15Cl2N3O2S
    N-[(1R)-1-(4-chlorophenyl)ethyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— (2S)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-cyclohexyl-N-methylpropanamide —— C18H22ClN3O2S
    (2S)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-cyclohexyl-N-methylpropanamide
    —— N-[(2-chlorophenyl)methyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C17H13Cl2N3O2S
    N-[(2-chlorophenyl)methyl]-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2R)-2-phenylpropyl]acetamide —— C19H18ClN3O2S
    2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(2R)-2-phenylpropyl]acetamide
    —— 2-(4-Chlorophenyl)-5-[(3-methylphenyl)methylsulfanyl]-1,3,4-oxadiazole —— C16H13ClN2OS
    2-(4-Chlorophenyl)-5-[(3-methylphenyl)methylsulfanyl]-1,3,4-oxadiazole
    —— (2R)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-cyclohexyl-N-methylpropanamide —— C18H22ClN3O2S
    (2R)-2-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-cyclohexyl-N-methylpropanamide