有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在,在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特,在药物设计、合成化学以及材料制备方面扮演着重要角色。
1. 结构与分类有机硫化合物可以按硫的连接方式分为饱和和不饱和类,如二硫化物、噻吩衍生物、砜等。常见的结构类型有:
许多有机硫化合物在生物学上有重要功能或应用潜力。例如:
有机硫化合物可通过多种途径合成:
有机硫化合物的应用广泛:
尽管有机硫化合物具有许多潜在益处,但其生产和使用也可能对环境造成影响。因此,在设计和合成这些化合物时需要考虑可持续性和环保性因素。
以上是对有机硫化合物的简单介绍,包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。
中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
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—— | N-[4-[(1R)-1-[(4-chloro-2-phenylsulfanyl-1,3-thiazol-5-yl)methylamino]ethyl]phenyl]cyclopropanecarboxamide | —— | C22H22ClN3OS2 |
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—— | N-[4-[(1S)-1-[(4-chloro-2-phenylsulfanyl-1,3-thiazol-5-yl)methylamino]ethyl]phenyl]cyclopropanecarboxamide | —— | C22H22ClN3OS2 |
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—— | (1R)-1-[5-[(3-bromo-4-fluorophenyl)methylsulfanyl]-4-butyl-1,2,4-triazol-3-yl]-N,N-dimethylpropan-1-amine | —— | C18H26BrFN4S |
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—— | (1S)-1-[5-[(3-bromo-4-fluorophenyl)methylsulfanyl]-4-butyl-1,2,4-triazol-3-yl]-N,N-dimethylpropan-1-amine | —— | C18H26BrFN4S |
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—— | 2-[(3-bromo-4-fluorophenyl)methylsulfanyl]-5-[(2S)-2-phenylpropyl]-1,3,4-oxadiazole | —— | C18H16BrFN2OS |
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—— | 1-(2-methylphenyl)-3-[(Z)-(4-methylsulfanylphenyl)methylideneamino]thiourea | —— | C16H17N3S2 |
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—— | 2-[(5-tert-butyl-1,3,4-oxadiazol-2-yl)sulfanyl]-1-[(2S,6R)-2,6-dimethylmorpholin-4-yl]ethanone | —— | C14H23N3O3S |
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—— | N-[(R)-cyclopentyl-(4-fluorophenyl)methyl]-2-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C21H23FN4OS2 |
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—— | 2-[(5-tert-butyl-1,3,4-oxadiazol-2-yl)sulfanyl]-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]ethanone | —— | C14H23N3O3S |
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—— | 2-[(5-tert-butyl-1,3,4-oxadiazol-2-yl)sulfanyl]-1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]ethanone | —— | C14H23N3O3S |
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—— | N-[(S)-cyclopentyl-(4-fluorophenyl)methyl]-2-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide | —— | C21H23FN4OS2 |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-4-amine | —— | C15H14F2N4OS |
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—— | 3-cyclopropyl-5-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-(furan-2-ylmethyl)-1,2,4-triazole | —— | C18H17F2N3OS |
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—— | 3-cyclopropyl-5-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-(furan-2-ylmethyl)-1,2,4-triazole | —— | C18H17F2N3OS |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-methyl-4-prop-2-enyl-1,2,4-triazole | —— | C14H15F2N3S |
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—— | 4-benzyl-3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(2-methylfuran-3-yl)-1,2,4-triazole | —— | C22H19F2N3OS |
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—— | 3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazole | —— | C16H15F2N3OS |
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—— | 5-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-3-phenyl-1,3,4-thiadiazole-2-thione | —— | C16H12F2N2S3 |
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—— | 5-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-3-phenyl-1,3,4-thiadiazole-2-thione | —— | C16H12F2N2S3 |
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—— | 3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(2-methylfuran-3-yl)-4-prop-2-enyl-1,2,4-triazole | —— | C18H17F2N3OS |
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—— | 3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(2-methylfuran-3-yl)-1,2,4-triazol-4-amine | —— | C15H14F2N4OS |
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—— | 4-[2-[4-(2,5-Dimethylphenyl)sulfanylanilino]-2-oxoethoxy]benzamide | —— | C23H22N2O3S |
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—— | 3-tert-butyl-5-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1,2,4-triazol-4-amine | —— | C14H18F2N4S |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-[[(2R)-oxolan-2-yl]methyl]-5-thiophen-2-yl-1,2,4-triazole | —— | C19H19F2N3OS2 |
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—— | 4-benzyl-3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(2-methylfuran-3-yl)-1,2,4-triazole | —— | C22H19F2N3OS |
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—— | 2-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-phenyl-1,3,4-oxadiazole | —— | C16H12F2N2OS |
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—— | 4-[2-Oxo-2-(2-phenylsulfanylanilino)ethoxy]benzamide | —— | C21H18N2O3S |
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—— | 2-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(2-methylfuran-3-yl)-1,3,4-oxadiazole | —— | C15H12F2N2O2S |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-[[(2S)-oxolan-2-yl]methyl]-5-thiophen-2-yl-1,2,4-triazole | —— | C19H19F2N3OS2 |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-methyl-1,2,4-triazole | —— | C11H11F2N3S |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(2-methylfuran-3-yl)-4-prop-2-enyl-1,2,4-triazole | —— | C18H17F2N3OS |
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—— | 3-tert-butyl-5-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1,2,4-triazol-4-amine | —— | C14H18F2N4S |
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—— | 3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-methyl-1,2,4-triazole | —— | C11H11F2N3S |
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—— | 1-[[5-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1,3,4-oxadiazol-2-yl]methyl]pyrrolidin-2-one | —— | C15H15F2N3O2S |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-methyl-5-(2-methylfuran-3-yl)-1,2,4-triazole | —— | C16H15F2N3OS |
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—— | 5-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1-methyltetrazole | —— | C10H10F2N4S |
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—— | 3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-[[(2R)-oxolan-2-yl]methyl]-5-thiophen-2-yl-1,2,4-triazole | —— | C19H19F2N3OS2 |
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—— | 7-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-3,4-dihydro-2H-1,5-benzodioxepine | —— | C17H16F2O2S |
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—— | 3-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(trifluoromethyl)-1,2,4-triazol-4-amine | —— | C11H9F5N4S |
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—— | 3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-4-[[(2S)-oxolan-2-yl]methyl]-5-thiophen-2-yl-1,2,4-triazole | —— | C19H19F2N3OS2 |
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—— | 2-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1-methylimidazole | —— | C12H12F2N2S |
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—— | 5-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1-methyltetrazole | —— | C10H10F2N4S |
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—— | 7-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-3,4-dihydro-2H-1,5-benzodioxepine | —— | C17H16F2O2S |
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—— | 5-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1,3,4-thiadiazol-2-amine | —— | C10H9F2N3S2 |
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—— | 3-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-5-(trifluoromethyl)-1,2,4-triazol-4-amine | —— | C11H9F5N4S |
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—— | 2-(4-chlorophenyl)-5-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1,3,4-oxadiazole | —— | C16H11ClF2N2OS |
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—— | 5-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1,3,4-thiadiazol-2-amine | —— | C10H9F2N3S2 |
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—— | 1-[[5-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1,3,4-oxadiazol-2-yl]methyl]pyrrolidin-2-one | —— | C15H15F2N3O2S |
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—— | 2-[(1S)-1-(2,6-difluorophenyl)ethyl]sulfanylpyridine | —— | C13H11F2NS |
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—— | 2-[(1R)-1-(2,6-difluorophenyl)ethyl]sulfanyl-1-methylimidazole | —— | C12H12F2N2S |
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