摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(2,4-difluorophenyl)sulfanyl-N-[[4-(dimethylamino)phenyl]methyl]acetamide —— C17H18F2N2OS
    2-(2,4-difluorophenyl)sulfanyl-N-[[4-(dimethylamino)phenyl]methyl]acetamide
    —— 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]ethanone —— C19H26N4O2S
    2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]ethanone
    —— N-[[4-(dimethylamino)phenyl]methyl]-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C19H20FN5OS2
    N-[[4-(dimethylamino)phenyl]methyl]-2-[[5-(3-fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— 2-(2,5-difluorophenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C16H17F2NOS2
    2-(2,5-difluorophenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— 2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[[4-(dimethylamino)phenyl]methyl]-N-methylacetamide —— C17H23N5OS2
    2-[[5-(cyclopropylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[[4-(dimethylamino)phenyl]methyl]-N-methylacetamide
    —— 2-Ethanimidoyl-4-[[5-(furan-2-ylmethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-3-oxobutanenitrile —— C13H13N5O2S2
    2-Ethanimidoyl-4-[[5-(furan-2-ylmethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-3-oxobutanenitrile
    —— 5-({[3-(2-thienyl)-1,2,4-oxadiazol-5-yl]methyl}thio)-1H-1,2,4-triazol-3-amine —— C9H8N6OS2
    5-({[3-(2-thienyl)-1,2,4-oxadiazol-5-yl]methyl}thio)-1H-1,2,4-triazol-3-amine
    —— N-(2-benzylsulfanylethyl)-2-[(6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetamide —— C15H17N3O2S2
    N-(2-benzylsulfanylethyl)-2-[(6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetamide
    —— 3-(4-fluorophenyl)sulfanyl-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]propanamide —— C17H20FNOS2
    3-(4-fluorophenyl)sulfanyl-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]propanamide
    —— N-[[4-(dimethylamino)phenyl]methyl]-2-[(4-pentyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C18H27N5OS
    N-[[4-(dimethylamino)phenyl]methyl]-2-[(4-pentyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C18H22N4O2S2
    2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C18H22N4O2S2
    2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— 2-{[(5-Amino-4H-1,2,4-triazol-3-YL)sulfanyl]methyl}-6,7,8,9-tetrahydro-4H-pyrimido[2,1-B][1,3]benzothiazol-4-one —— C13H14N6OS2
    2-{[(5-Amino-4H-1,2,4-triazol-3-YL)sulfanyl]methyl}-6,7,8,9-tetrahydro-4H-pyrimido[2,1-B][1,3]benzothiazol-4-one
    —— (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-propylpropanamide —— C19H22N4OS2
    (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-propylpropanamide
    —— 2-(3,4-dimethylphenyl)sulfanyl-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C18H23NOS2
    2-(3,4-dimethylphenyl)sulfanyl-N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— 2-(3,4-dimethylphenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C18H23NOS2
    2-(3,4-dimethylphenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— N,N-dimethyl-1-[4-methyl-5-[(3S)-1-[(2-propylsulfanylpyrimidin-5-yl)methyl]piperidin-3-yl]-1,2,4-triazol-3-yl]methanamine —— C19H31N7S
    N,N-dimethyl-1-[4-methyl-5-[(3S)-1-[(2-propylsulfanylpyrimidin-5-yl)methyl]piperidin-3-yl]-1,2,4-triazol-3-yl]methanamine
    —— N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]-2-phenylsulfanylacetamide —— C16H19NOS2
    N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]-2-phenylsulfanylacetamide
    —— N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]-2-phenylsulfanylacetamide —— C16H19NOS2
    N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]-2-phenylsulfanylacetamide
    —— (2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-propylpropanamide —— C19H22N4O2S
    (2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-propylpropanamide
    —— N,N-dimethyl-1-[4-methyl-5-[(3R)-1-[(2-propylsulfanylpyrimidin-5-yl)methyl]piperidin-3-yl]-1,2,4-triazol-3-yl]methanamine —— C19H31N7S
    N,N-dimethyl-1-[4-methyl-5-[(3R)-1-[(2-propylsulfanylpyrimidin-5-yl)methyl]piperidin-3-yl]-1,2,4-triazol-3-yl]methanamine
    —— (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N,N-di(propan-2-yl)propanamide —— C22H28N4O2S
    (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N,N-di(propan-2-yl)propanamide
    —— 2-(2-methylphenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C17H21NOS2
    2-(2-methylphenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-cycloheptylpropanamide —— C23H28N4O2S
    (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-cycloheptylpropanamide
    —— (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-tert-butylpropanamide —— C20H24N4OS2
    (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-tert-butylpropanamide
    —— (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxyethyl)propanamide —— C19H22N4O3S
    (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxyethyl)propanamide
    —— (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide —— C16H22N4O3S3
    (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide
    —— 2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]-N-[[4-(dimethylamino)phenyl]methyl]-N-methylacetamide —— C14H20N6OS
    2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]-N-[[4-(dimethylamino)phenyl]methyl]-N-methylacetamide
    —— (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C15H20N4O3S3
    (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-N-(2-cyanoethyl)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide —— C15H19N5OS2
    (2S)-N-(2-cyanoethyl)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide
    —— (2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxyethyl)propanamide —— C19H22N4O3S
    (2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxyethyl)propanamide
    —— (2S)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-cyanoethyl)-N-methylpropanamide —— C20H21N5OS2
    (2S)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-cyanoethyl)-N-methylpropanamide
    —— (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)propanamide —— C19H22N4O2S2
    (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)propanamide
    —— (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(thiophen-2-ylmethyl)propanamide —— C16H18N4OS3
    (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(thiophen-2-ylmethyl)propanamide
    —— (2R)-N-tert-butyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C15H22N4OS2
    (2R)-N-tert-butyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-propylpropanamide —— C19H22N4OS2
    (2S)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-propylpropanamide
    —— (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-prop-2-enylpropanamide —— C19H20N4OS2
    (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-prop-2-enylpropanamide
    —— methyl N-[(2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]carbamate —— C13H16N4O3S2
    methyl N-[(2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]carbamate
    —— (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(4-methylphenyl)methyl]propanamide —— C19H22N4OS2
    (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(4-methylphenyl)methyl]propanamide
    —— 2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]-N-[3-(N-methylanilino)propyl]acetamide —— C14H20N6OS
    2-[(4-amino-1,2,4-triazol-3-yl)sulfanyl]-N-[3-(N-methylanilino)propyl]acetamide
    —— 2-(4-fluorophenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide —— C16H18FNOS2
    2-(4-fluorophenyl)sulfanyl-N-[(1R)-2-methyl-1-thiophen-2-ylpropyl]acetamide
    —— (2S)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-tert-butylpropanamide —— C20H24N4OS2
    (2S)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-tert-butylpropanamide
    —— methyl N-[(2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propanoyl]carbamate —— C18H18N4O4S
    methyl N-[(2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propanoyl]carbamate
    —— (2S)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(4-methylphenyl)methyl]propanamide —— C19H22N4OS2
    (2S)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(4-methylphenyl)methyl]propanamide
    —— (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)propanamide —— C14H20N4O2S2
    (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)propanamide
    —— (2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-prop-2-enylpropanamide —— C19H20N4O2S
    (2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-prop-2-enylpropanamide
    —— (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide —— C16H22N4O3S3
    (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide
    —— methyl N-[(2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propanoyl]carbamate —— C18H18N4O4S
    methyl N-[(2S)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propanoyl]carbamate
    —— (2S)-N-cycloheptyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C18H26N4OS2
    (2S)-N-cycloheptyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)propanamide —— C14H20N4O2S2
    (2S)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)propanamide