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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2R)-N-ethyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C13H18N4OS2
    (2R)-N-ethyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— [2-oxo-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C21H19F2NO3S
    [2-oxo-2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[(1-Cyanocyclohexyl)-methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H20F2N2O3S
    [2-[(1-Cyanocyclohexyl)-methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— (2S)-N-ethyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C13H18N4OS2
    (2S)-N-ethyl-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— [2-[[(1R)-1-(2,4-difluorophenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H15F4NO3S
    [2-[[(1R)-1-(2,4-difluorophenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(1R)-1-cyano-1-cyclopropylethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C16H16F2N2O3S
    [2-[[(1R)-1-cyano-1-cyclopropylethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(1R)-1-cyclopropylethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C15H17F2NO3S
    [2-[[(1R)-1-cyclopropylethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-ethylpropanamide —— C18H20N4O2S
    (2R)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-ethylpropanamide
    —— [2-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C19H16F2O5S
    [2-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(1S)-1-(4-ethylphenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C20H21F2NO3S
    [2-[[(1S)-1-(4-ethylphenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-(2-Methylbutan-2-ylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C15H19F2NO3S
    [2-(2-Methylbutan-2-ylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(1S)-1-(3-chlorophenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H16ClF2NO3S
    [2-[[(1S)-1-(3-chlorophenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(1S,2S)-2-methylcyclohexyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C17H21F2NO3S
    [2-[[(1S,2S)-2-methylcyclohexyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2R)-1-oxo-1-(propan-2-ylamino)propan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C14H17F2NO3S
    [(2R)-1-oxo-1-(propan-2-ylamino)propan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-oxo-2-[[(1S)-1-phenylbutyl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C20H21F2NO3S
    [2-oxo-2-[[(1S)-1-phenylbutyl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-ethylpropanamide —— C18H20N4OS2
    (2R)-2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-ethylpropanamide
    —— [2-(1-Adamantylmethylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C21H25F2NO3S
    [2-(1-Adamantylmethylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[(2-Fluorophenyl)methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C17H14F3NO3S
    [2-[(2-Fluorophenyl)methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2S)-1-[(1-cyanocyclohexyl)amino]-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H20F2N2O3S
    [(2S)-1-[(1-cyanocyclohexyl)amino]-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-oxo-2-[[(1R)-1-phenylbutyl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C20H21F2NO3S
    [2-oxo-2-[[(1R)-1-phenylbutyl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— 2-[(1S)-1-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-5-(4-fluorophenyl)-1,3,4-oxadiazole —— C18H16FN5OS2
    2-[(1S)-1-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-5-(4-fluorophenyl)-1,3,4-oxadiazole
    —— [2-[[4-(Dimethylamino)phenyl]methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C19H20F2N2O3S
    [2-[[4-(Dimethylamino)phenyl]methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(1R)-1-(furan-2-yl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C16H15F2NO4S
    [2-[[(1R)-1-(furan-2-yl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— methyl 5-[(2S)-2-[2-(2,5-difluorophenyl)sulfanylacetyl]oxypropanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C19H19F2NO5S
    methyl 5-[(2S)-2-[2-(2,5-difluorophenyl)sulfanylacetyl]oxypropanoyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— [2-[[4-(Dimethylamino)phenyl]methyl-methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C20H22F2N2O3S
    [2-[[4-(Dimethylamino)phenyl]methyl-methylamino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2R)-1-(ethylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C13H15F2NO3S
    [(2R)-1-(ethylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2S)-1-(ethylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C13H15F2NO3S
    [(2S)-1-(ethylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(3S)-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C14H15F2NO5S2
    [2-[[(3S)-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2S)-1-oxo-1-(propan-2-ylamino)propan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C14H17F2NO3S
    [(2S)-1-oxo-1-(propan-2-ylamino)propan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [5-(2,5-Dimethylfuran-3-yl)-1,3,4-oxadiazol-2-yl]methyl 2-(2,5-difluorophenyl)sulfanylacetate —— C17H14F2N2O4S
    [5-(2,5-Dimethylfuran-3-yl)-1,3,4-oxadiazol-2-yl]methyl 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-oxo-2-[[(1R)-1-phenylethyl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H17F2NO3S
    [2-oxo-2-[[(1R)-1-phenylethyl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-Oxo-2-(2-thiophen-2-ylethylamino)ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C16H15F2NO3S2
    [2-Oxo-2-(2-thiophen-2-ylethylamino)ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N,N-dimethylpropanamide —— C13H18N4OS2
    (2R)-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N,N-dimethylpropanamide
    —— [2-Oxo-2-(2,4,4-trimethylpentan-2-ylamino)ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H25F2NO3S
    [2-Oxo-2-(2,4,4-trimethylpentan-2-ylamino)ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2R)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C16H19F2NO3S
    [(2R)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— ethyl 5-[2-[2-(2,5-difluorophenyl)sulfanylacetyl]oxyacetyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate —— C19H19F2NO5S
    ethyl 5-[2-[2-(2,5-difluorophenyl)sulfanylacetyl]oxyacetyl]-2,4-dimethyl-1H-pyrrole-3-carboxylate
    —— [2-(Furan-2-ylmethylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C15H13F2NO4S
    [2-(Furan-2-ylmethylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-(Methylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C11H11F2NO3S
    [2-(Methylamino)-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(1R)-1-(3-chlorophenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H16ClF2NO3S
    [2-[[(1R)-1-(3-chlorophenyl)ethyl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-oxo-2-[[(2S)-oxolan-2-yl]methylamino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C15H17F2NO4S
    [2-oxo-2-[[(2S)-oxolan-2-yl]methylamino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [5-(3-Methylphenyl)-1,3,4-oxadiazol-2-yl]methyl 2-(2,5-difluorophenyl)sulfanylacetate —— C18H14F2N2O3S
    [5-(3-Methylphenyl)-1,3,4-oxadiazol-2-yl]methyl 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(2R)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C15H19F2NO3S
    [2-[[(2R)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-oxo-2-[[(2S)-4-phenylbutan-2-yl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C20H21F2NO3S
    [2-oxo-2-[[(2S)-4-phenylbutan-2-yl]amino]ethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(2S)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C15H19F2NO3S
    [2-[[(2S)-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(3S)-3-methyl-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C15H17F2NO5S2
    [2-[[(3S)-3-methyl-1,1-dioxothiolan-3-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [2-[[(2S)-2-cyano-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate —— C16H18F2N2O3S
    [2-[[(2S)-2-cyano-3-methylbutan-2-yl]amino]-2-oxoethyl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— (5-Oxo-[1,3]thiazolo[3,2-a]pyrimidin-7-yl)methyl 2-(2,5-difluorophenyl)sulfanylacetate —— C15H10F2N2O3S2
    (5-Oxo-[1,3]thiazolo[3,2-a]pyrimidin-7-yl)methyl 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2S)-1-(1-adamantylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C21H25F2NO3S
    [(2S)-1-(1-adamantylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2R)-1-[2-(cyclohexen-1-yl)ethylamino]-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C19H23F2NO3S
    [(2R)-1-[2-(cyclohexen-1-yl)ethylamino]-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate
    —— [(2S)-1-(benzylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate —— C18H17F2NO3S
    [(2S)-1-(benzylamino)-1-oxopropan-2-yl] 2-(2,5-difluorophenyl)sulfanylacetate