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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2R)-2-ethylsulfonyl-N-prop-2-enylpropanamide —— C8H15NO3S
    (2R)-2-ethylsulfonyl-N-prop-2-enylpropanamide
    —— (2S)-2-ethylsulfonyl-N-prop-2-enylpropanamide —— C8H15NO3S
    (2S)-2-ethylsulfonyl-N-prop-2-enylpropanamide
    —— (2R)-N-cyclohexyl-2-ethylsulfonyl-N-methylpropanamide —— C12H23NO3S
    (2R)-N-cyclohexyl-2-ethylsulfonyl-N-methylpropanamide
    —— (2R)-N-tert-butyl-2-methylsulfonylpropanamide —— C8H17NO3S
    (2R)-N-tert-butyl-2-methylsulfonylpropanamide
    —— (2R)-N-tert-butyl-2-ethylsulfonylpropanamide —— C9H19NO3S
    (2R)-N-tert-butyl-2-ethylsulfonylpropanamide
    —— (2S)-2-ethylsulfonyl-N-[(1S,2S)-2-methylcyclohexyl]propanamide —— C12H23NO3S
    (2S)-2-ethylsulfonyl-N-[(1S,2S)-2-methylcyclohexyl]propanamide
    —— 5-{[(2,4-Dimethylphenyl)methyl]sulfanyl}-3-(2-methylphenyl)-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-D]pyrimidin-7-one —— C27H23N3OS3
    5-{[(2,4-Dimethylphenyl)methyl]sulfanyl}-3-(2-methylphenyl)-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-D]pyrimidin-7-one
    —— 3-[2-(4-methyl-1,3-thiazol-5-yl)ethylsulfanyl]-4-[[(2S)-oxolan-2-yl]methyl]-1H-1,2,4-triazol-5-one —— C13H18N4O2S2
    3-[2-(4-methyl-1,3-thiazol-5-yl)ethylsulfanyl]-4-[[(2S)-oxolan-2-yl]methyl]-1H-1,2,4-triazol-5-one
    —— 5-[2-(4-methyl-1,3-thiazol-5-yl)ethylsulfanyl]-N-[[(2S)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine —— C13H18N4OS3
    5-[2-(4-methyl-1,3-thiazol-5-yl)ethylsulfanyl]-N-[[(2S)-oxolan-2-yl]methyl]-1,3,4-thiadiazol-2-amine
    —— (2S,3R)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine —— C9H18BrNO2S
    (2S,3R)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine
    —— (2R,3S)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine —— C9H18BrNO2S
    (2R,3S)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine
    —— (2R,3R)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine —— C9H18BrNO2S
    (2R,3R)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine
    —— (2S,3R)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine —— C9H17NO2S
    (2S,3R)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine
    —— (2S,3S)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine —— C9H18BrNO2S
    (2S,3S)-N-(2-bromoprop-2-enyl)-N-methyl-3-methylsulfonylbutan-2-amine
    —— (2R,3R)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine —— C9H17NO2S
    (2R,3R)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine
    —— (2R,3S)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine —— C9H17NO2S
    (2R,3S)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine
    —— (2S,3S)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine —— C9H17NO2S
    (2S,3S)-N-methyl-3-methylsulfonyl-N-prop-2-ynylbutan-2-amine
    —— 2-cyclopentylsulfonyl-N-[(1S,2R,4S)-2,4-dimethylcyclohexyl]acetamide —— C15H27NO3S
    2-cyclopentylsulfonyl-N-[(1S,2R,4S)-2,4-dimethylcyclohexyl]acetamide
    —— 2-cyclopentylsulfonyl-N-[(1R,2R,4R)-2,4-dimethylcyclohexyl]acetamide —— C15H27NO3S
    2-cyclopentylsulfonyl-N-[(1R,2R,4R)-2,4-dimethylcyclohexyl]acetamide
    —— 2-cyclopentylsulfonyl-N-[(1R,2R,4S)-2,4-dimethylcyclohexyl]acetamide —— C15H27NO3S
    2-cyclopentylsulfonyl-N-[(1R,2R,4S)-2,4-dimethylcyclohexyl]acetamide
    —— N-[(2S)-1-ethylsulfonylpropan-2-yl]-N-methyl-2-phenylsulfanylacetamide —— C14H21NO3S2
    N-[(2S)-1-ethylsulfonylpropan-2-yl]-N-methyl-2-phenylsulfanylacetamide
    —— N-[(2R)-1-ethylsulfonylpropan-2-yl]-N-methyl-2-phenylsulfanylacetamide —— C14H21NO3S2
    N-[(2R)-1-ethylsulfonylpropan-2-yl]-N-methyl-2-phenylsulfanylacetamide
    —— (2R)-N-(2-methylpentan-2-yl)-2-propylsulfonylpropanamide —— C12H25NO3S
    (2R)-N-(2-methylpentan-2-yl)-2-propylsulfonylpropanamide
    —— (2S)-N-(2-methylpentan-2-yl)-2-propylsulfonylpropanamide —— C12H25NO3S
    (2S)-N-(2-methylpentan-2-yl)-2-propylsulfonylpropanamide
    —— N-[2-(4-chlorophenyl)ethyl]-2-[(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide —— C13H14ClN3OS3
    N-[2-(4-chlorophenyl)ethyl]-2-[(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide
    —— 2-(2-fluorophenyl)sulfanylethyl (E)-2-cyano-3-(2,5-dimethyl-1-propylpyrrol-3-yl)prop-2-enoate —— C21H23FN2O2S
    2-(2-fluorophenyl)sulfanylethyl (E)-2-cyano-3-(2,5-dimethyl-1-propylpyrrol-3-yl)prop-2-enoate
    —— 2-[(1S)-1-(4-fluorophenyl)ethyl]sulfanyl-5-(4-methylphenyl)-1,3,4-oxadiazole —— C17H15FN2OS
    2-[(1S)-1-(4-fluorophenyl)ethyl]sulfanyl-5-(4-methylphenyl)-1,3,4-oxadiazole
    —— (2R)-N-cyclopentyl-2-methylsulfonyl-N-prop-2-enylpropanamide —— C12H21NO3S
    (2R)-N-cyclopentyl-2-methylsulfonyl-N-prop-2-enylpropanamide
    —— N-[(2R)-1-methoxypropan-2-yl]-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C15H19N3O3S
    N-[(2R)-1-methoxypropan-2-yl]-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— N-[(2S)-1-methoxypropan-2-yl]-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C15H19N3O3S
    N-[(2S)-1-methoxypropan-2-yl]-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— (2S)-N-cyclopentyl-2-methylsulfonyl-N-prop-2-enylpropanamide —— C12H21NO3S
    (2S)-N-cyclopentyl-2-methylsulfonyl-N-prop-2-enylpropanamide
    —— 1-[2-[(5-Methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetyl]pyrrolidin-2-one —— C9H11N3O2S3
    1-[2-[(5-Methylsulfanyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetyl]pyrrolidin-2-one
    —— 3-propan-2-yl-5-[(1R)-1-[1-(pyridin-2-ylmethyl)imidazol-2-yl]sulfanylethyl]-1,2,4-oxadiazole —— C16H19N5OS
    3-propan-2-yl-5-[(1R)-1-[1-(pyridin-2-ylmethyl)imidazol-2-yl]sulfanylethyl]-1,2,4-oxadiazole
    —— 3-propan-2-yl-5-[(1S)-1-[1-(pyridin-2-ylmethyl)imidazol-2-yl]sulfanylethyl]-1,2,4-oxadiazole —— C16H19N5OS
    3-propan-2-yl-5-[(1S)-1-[1-(pyridin-2-ylmethyl)imidazol-2-yl]sulfanylethyl]-1,2,4-oxadiazole
    —— 2-[[4-cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methoxypropyl)acetamide —— C19H28N4O2S2
    2-[[4-cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methoxypropyl)acetamide
    —— N-[2-[(R)-tert-butylsulfinyl]ethyl]-2-cyclopentylsulfonylacetamide —— C13H25NO4S2
    N-[2-[(R)-tert-butylsulfinyl]ethyl]-2-cyclopentylsulfonylacetamide
    —— N-[2-[(S)-tert-butylsulfinyl]ethyl]-2-cyclopentylsulfonylacetamide —— C13H25NO4S2
    N-[2-[(S)-tert-butylsulfinyl]ethyl]-2-cyclopentylsulfonylacetamide
    —— 2-[[4-Cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-thiophen-2-ylethanone —— C19H21N3OS3
    2-[[4-Cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-thiophen-2-ylethanone
    —— N'-acetyl-2-[[4-cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]acetohydrazide —— C17H23N5O2S2
    N'-acetyl-2-[[4-cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]acetohydrazide
    —— 2-[[4-Cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]-5-methyl-1,3,4-oxadiazole —— C17H21N5OS2
    2-[[4-Cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]-5-methyl-1,3,4-oxadiazole
    —— N-[2-[(R)-tert-butylsulfinyl]ethyl]-2-phenylsulfanylacetamide —— C14H21NO2S2
    N-[2-[(R)-tert-butylsulfinyl]ethyl]-2-phenylsulfanylacetamide
    —— N-[2-[(S)-tert-butylsulfinyl]ethyl]-2-phenylsulfanylacetamide —— C14H21NO2S2
    N-[2-[(S)-tert-butylsulfinyl]ethyl]-2-phenylsulfanylacetamide
    —— N-[2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C17H22N2O3S2
    N-[2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethyl]-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-methyl-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C13H19NOS
    N-methyl-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— N-(2-cyanoethyl)-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide —— C15H20N2OS
    N-(2-cyanoethyl)-2-(2,3,5,6-tetramethylphenyl)sulfanylacetamide
    —— (2S)-N-ethyl-N-[[(3S)-oxolan-3-yl]methyl]-2-phenylsulfanylbutanamide —— C17H25NO2S
    (2S)-N-ethyl-N-[[(3S)-oxolan-3-yl]methyl]-2-phenylsulfanylbutanamide
    —— (2S)-N-ethyl-N-[[(3R)-oxolan-3-yl]methyl]-2-phenylsulfanylbutanamide —— C17H25NO2S
    (2S)-N-ethyl-N-[[(3R)-oxolan-3-yl]methyl]-2-phenylsulfanylbutanamide
    —— (2S)-N-[1-(2,2-difluoroethyl)piperidin-4-yl]-2-phenylsulfanylbutanamide —— C17H24F2N2OS
    (2S)-N-[1-(2,2-difluoroethyl)piperidin-4-yl]-2-phenylsulfanylbutanamide
    —— (2R)-N-[1-(2,2-difluoroethyl)piperidin-4-yl]-2-phenylsulfanylbutanamide —— C17H24F2N2OS
    (2R)-N-[1-(2,2-difluoroethyl)piperidin-4-yl]-2-phenylsulfanylbutanamide
    —— (2R)-N-ethyl-N-[[(3S)-oxolan-3-yl]methyl]-2-phenylsulfanylbutanamide —— C17H25NO2S
    (2R)-N-ethyl-N-[[(3S)-oxolan-3-yl]methyl]-2-phenylsulfanylbutanamide