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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R,2R)-2-methylcyclohexyl]acetamide —— C18H24N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R,2R)-2-methylcyclohexyl]acetamide
    —— 7-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one —— C16H13N5OS3
    7-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S,2S)-2-methylcyclohexyl]acetamide —— C18H24N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S,2S)-2-methylcyclohexyl]acetamide
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2S)-4-phenylbutan-2-yl]acetamide —— C21H24N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2S)-4-phenylbutan-2-yl]acetamide
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-methylbutyl)acetamide —— C16H22N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-methylbutyl)acetamide
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methylpropyl)acetamide —— C15H20N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methylpropyl)acetamide
    —— N,N-bis(2-cyanoethyl)-2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C17H18N6OS2
    N,N-bis(2-cyanoethyl)-2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[1-(2-methoxyethyl)-2,5-dimethylpyrrol-3-yl]ethanone —— C20H24N4O2S2
    2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[1-(2-methoxyethyl)-2,5-dimethylpyrrol-3-yl]ethanone
    —— N-benzyl-2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-ethylacetamide —— C20H22N4OS2
    N-benzyl-2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-ethylacetamide
    —— 2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-pyrrolidin-1-ylethanone —— C15H18N4OS2
    2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-pyrrolidin-1-ylethanone
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)acetamide —— C14H18N4O2S2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyethyl)acetamide
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-propan-2-ylacetamide —— C14H18N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-propan-2-ylacetamide
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone —— C21H28N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone
    —— 4-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-3,5-dimethyl-1,2-oxazole —— C15H16N4OS2
    4-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-3,5-dimethyl-1,2-oxazole
    —— (3R)-3-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]oxolan-2-one —— C13H13N3O2S2
    (3R)-3-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]oxolan-2-one
    —— 2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetonitrile —— C11H10N4S2
    2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetonitrile
    —— (2S)-2-[[5,6-bis(4-methylphenyl)-1,2,4-triazin-3-yl]sulfanyl]-1-pyrrolidin-1-ylpropan-1-one —— C24H26N4OS
    (2S)-2-[[5,6-bis(4-methylphenyl)-1,2,4-triazin-3-yl]sulfanyl]-1-pyrrolidin-1-ylpropan-1-one
    —— 2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-thiophen-2-ylethanone —— C15H13N3OS3
    2-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-thiophen-2-ylethanone
    —— N-cycloheptyl-2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C18H24N4OS2
    N-cycloheptyl-2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 3-[(3-Chlorophenyl)methylsulfanyl]-4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazole —— C16H14ClN3S2
    3-[(3-Chlorophenyl)methylsulfanyl]-4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazole
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(1R,5S)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone —— C21H28N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(1R,5S)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl]ethanone
    —— 3-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanenitrile —— C12H12N4S2
    3-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propanenitrile
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2R,6S)-2,6-dimethylmorpholin-4-yl]ethanone —— C17H22N4O2S2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2R,6S)-2,6-dimethylmorpholin-4-yl]ethanone
    —— 4-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-phenyl-1,3-thiazole —— C19H16N4S3
    4-[(4-Cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-phenyl-1,3-thiazole
    —— 4-Cyclopropyl-3-[(4-fluorophenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole —— C16H14FN3S2
    4-Cyclopropyl-3-[(4-fluorophenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole
    —— 3-[(4-Chlorophenyl)methylsulfanyl]-4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazole —— C16H14ClN3S2
    3-[(4-Chlorophenyl)methylsulfanyl]-4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazole
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]ethanone —— C17H22N4O2S2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2R,6R)-2,6-dimethylmorpholin-4-yl]ethanone
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-4-phenylbutan-2-yl]acetamide —— C21H24N4OS2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-4-phenylbutan-2-yl]acetamide
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(furan-2-ylmethyl)acetamide —— C16H16N4O2S2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(furan-2-ylmethyl)acetamide
    —— 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]ethanone —— C17H22N4O2S2
    2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-1-[(2S,6S)-2,6-dimethylmorpholin-4-yl]ethanone
    —— 2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-phenylsulfanylethyl)acetamide —— C18H16ClN3O2S2
    2-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-phenylsulfanylethyl)acetamide
    —— [2-Oxo-2-(2-phenylsulfanylanilino)ethyl] 2,5-dimethylthiophene-3-carboxylate —— C21H19NO3S2
    [2-Oxo-2-(2-phenylsulfanylanilino)ethyl] 2,5-dimethylthiophene-3-carboxylate
    —— (3-Cyano-4-imino-2-oxopentyl) 3-(4-fluorophenyl)sulfanylpropanoate —— C15H15FN2O3S
    (3-Cyano-4-imino-2-oxopentyl) 3-(4-fluorophenyl)sulfanylpropanoate
    —— N-[(2,4-dimethylphenyl)methyl]-2-[[5-(3,5-dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-methylacetamide —— C22H25N3O2S
    N-[(2,4-dimethylphenyl)methyl]-2-[[5-(3,5-dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-methylacetamide
    —— (2R)-1-(3-chlorophenyl)sulfanylpropan-2-amine —— C9H12ClNS
    (2R)-1-(3-chlorophenyl)sulfanylpropan-2-amine
    —— (2S)-1-(3-chlorophenyl)sulfanylpropan-2-amine —— C9H12ClNS
    (2S)-1-(3-chlorophenyl)sulfanylpropan-2-amine
    —— (2R)-1-(4-fluoro-2-methylphenyl)sulfanylpropan-2-amine —— C10H14FNS
    (2R)-1-(4-fluoro-2-methylphenyl)sulfanylpropan-2-amine
    —— (2R)-1-(4-fluoro-3-methylphenyl)sulfanylpropan-2-amine —— C10H14FNS
    (2R)-1-(4-fluoro-3-methylphenyl)sulfanylpropan-2-amine
    —— (2S)-1-(4-fluoro-3-methylphenyl)sulfanylpropan-2-amine —— C10H14FNS
    (2S)-1-(4-fluoro-3-methylphenyl)sulfanylpropan-2-amine
    —— (2S)-1-(4-fluoro-2-methylphenyl)sulfanylpropan-2-amine —— C10H14FNS
    (2S)-1-(4-fluoro-2-methylphenyl)sulfanylpropan-2-amine
    —— (2R)-1-(3,4-dimethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2R)-1-(3,4-dimethylphenyl)sulfanylpropan-2-amine
    —— (2R)-1-(2,5-dimethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2R)-1-(2,5-dimethylphenyl)sulfanylpropan-2-amine
    —— (2S)-1-(2,5-dimethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2S)-1-(2,5-dimethylphenyl)sulfanylpropan-2-amine
    —— (2S)-1-(4-ethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2S)-1-(4-ethylphenyl)sulfanylpropan-2-amine
    —— (2S)-1-(2,4-dimethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2S)-1-(2,4-dimethylphenyl)sulfanylpropan-2-amine
    —— (2R)-1-(2,4-dimethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2R)-1-(2,4-dimethylphenyl)sulfanylpropan-2-amine
    —— (2S)-1-(3,4-dimethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2S)-1-(3,4-dimethylphenyl)sulfanylpropan-2-amine
    —— (2R)-1-(4-ethylphenyl)sulfanylpropan-2-amine —— C11H17NS
    (2R)-1-(4-ethylphenyl)sulfanylpropan-2-amine
    —— N-[2-(4-chlorophenyl)sulfanylethyl]-2-[2-oxo-5-(trifluoromethyl)pyridin-1-yl]acetamide —— C16H14ClF3N2O2S
    N-[2-(4-chlorophenyl)sulfanylethyl]-2-[2-oxo-5-(trifluoromethyl)pyridin-1-yl]acetamide
    —— N-[2-(4-methylphenyl)sulfanylethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C14H18N4OS2
    N-[2-(4-methylphenyl)sulfanylethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide