摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[(6-oxo-4-propyl-1H-pyrimidin-2-yl)sulfanyl]-N-[(1R)-1-phenylbutyl]acetamide —— C19H25N3O2S
    2-[(6-oxo-4-propyl-1H-pyrimidin-2-yl)sulfanyl]-N-[(1R)-1-phenylbutyl]acetamide
    —— 2-(1-oxidopyridin-1-ium-2-yl)sulfanyl-N-[(1R)-1-phenylbutyl]acetamide —— C17H20N2O2S
    2-(1-oxidopyridin-1-ium-2-yl)sulfanyl-N-[(1R)-1-phenylbutyl]acetamide
    —— 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(1S)-1-phenylbutyl]acetamide —— C14H18N4OS2
    2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(1S)-1-phenylbutyl]acetamide
    —— (3R)-3-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-methylpyrrolidin-2-one —— C13H12ClN3O2S
    (3R)-3-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-methylpyrrolidin-2-one
    —— (3S)-3-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-methylpyrrolidin-2-one —— C13H12ClN3O2S
    (3S)-3-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-methylpyrrolidin-2-one
    —— N-[(3S)-1-[2-(2-fluorophenyl)sulfanylethyl]piperidin-3-yl]acetamide —— C15H21FN2OS
    N-[(3S)-1-[2-(2-fluorophenyl)sulfanylethyl]piperidin-3-yl]acetamide
    —— N-[(3R)-1-[2-(2-fluorophenyl)sulfanylethyl]piperidin-3-yl]acetamide —— C15H21FN2OS
    N-[(3R)-1-[2-(2-fluorophenyl)sulfanylethyl]piperidin-3-yl]acetamide
    —— 2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-phenylbutyl]acetamide —— C14H19N5OS
    2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1S)-1-phenylbutyl]acetamide
    —— 2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-phenylbutyl]acetamide —— C14H19N5OS
    2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[(1R)-1-phenylbutyl]acetamide
    —— N-[4-(2,4-dimethylphenyl)sulfanylphenyl]-4-ethylbenzenesulfonamide —— C22H23NO2S2
    N-[4-(2,4-dimethylphenyl)sulfanylphenyl]-4-ethylbenzenesulfonamide
    —— (2R)-2-[[5-(3-bromoanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-thiophen-2-ylethyl)propanamide —— C17H17BrN4OS3
    (2R)-2-[[5-(3-bromoanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-thiophen-2-ylethyl)propanamide
    —— (2S)-2-[[5-(3-bromoanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-thiophen-2-ylethyl)propanamide —— C17H17BrN4OS3
    (2S)-2-[[5-(3-bromoanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(2-thiophen-2-ylethyl)propanamide
    —— 2-(3,4-difluorophenyl)sulfanyl-N-[(2S)-2-[(3R)-3-methylmorpholin-4-yl]propyl]acetamide —— C16H22F2N2O2S
    2-(3,4-difluorophenyl)sulfanyl-N-[(2S)-2-[(3R)-3-methylmorpholin-4-yl]propyl]acetamide
    —— (2Z,5Z)-2-[2-(furan-2-yl)-2-oxoethylidene]-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one —— C17H13NO3S2
    (2Z,5Z)-2-[2-(furan-2-yl)-2-oxoethylidene]-5-[(4-methylsulfanylphenyl)methylidene]-1,3-thiazolidin-4-one
    —— 2-(3,4-difluorophenyl)sulfanyl-N-[(2S)-2-[(3S)-3-methylmorpholin-4-yl]propyl]acetamide —— C16H22F2N2O2S
    2-(3,4-difluorophenyl)sulfanyl-N-[(2S)-2-[(3S)-3-methylmorpholin-4-yl]propyl]acetamide
    —— [(2R)-2,3-dihydro-1-benzothiophen-2-yl]-(4-pyridazin-3-yl-1,4-diazepan-1-yl)methanone —— C18H20N4OS
    [(2R)-2,3-dihydro-1-benzothiophen-2-yl]-(4-pyridazin-3-yl-1,4-diazepan-1-yl)methanone
    —— [(2S)-2,3-dihydro-1-benzothiophen-2-yl]-(4-pyridazin-3-yl-1,4-diazepan-1-yl)methanone —— C18H20N4OS
    [(2S)-2,3-dihydro-1-benzothiophen-2-yl]-(4-pyridazin-3-yl-1,4-diazepan-1-yl)methanone
    —— N-(1-cyanocyclohexyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C12H17N5OS
    N-(1-cyanocyclohexyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— N-[(2S)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H22N4O3S2
    N-[(2S)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 1-[(3S)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone —— C18H16ClN5O2S
    1-[(3S)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone
    —— (2S)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C14H17FN4OS
    (2S)-N-[(1S)-1-(4-fluorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— N-[(1R)-1-(2-chlorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H15ClN4OS
    N-[(1R)-1-(2-chlorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— N-[(2S)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H22N4O3S2
    N-[(2S)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— ethyl 2,4-dimethyl-5-[(2S)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]-1H-pyrrole-3-carboxylate —— C15H20N4O3S
    ethyl 2,4-dimethyl-5-[(2S)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]-1H-pyrrole-3-carboxylate
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-N-(2-methylpropyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H22N4O3S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-N-(2-methylpropyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— (2S)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C14H17FN4OS
    (2S)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— 2-[(4-Methyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-phenyl-3,4-dihydropyrazol-2-yl)ethanone —— C14H15N5OS
    2-[(4-Methyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5-phenyl-3,4-dihydropyrazol-2-yl)ethanone
    —— 2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2S)-4-phenylbutan-2-yl]acetamide —— C15H20N4OS
    2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2S)-4-phenylbutan-2-yl]acetamide
    —— N-(1-cyanocyclopentyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C11H15N5OS
    N-(1-cyanocyclopentyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— [(1S)-3-methyl-1-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)butyl]azanium —— C8H16N3OS+
    [(1S)-3-methyl-1-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)butyl]azanium
    —— (2R)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C14H17FN4OS
    (2R)-N-[(1R)-1-(4-fluorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— 4-Methyl-3-[[3-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]methylsulfanyl]-1,2,4-triazole —— C14H16N6S2
    4-Methyl-3-[[3-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]methylsulfanyl]-1,2,4-triazole
    —— 4-Methyl-3-[[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]methylsulfanyl]-1,2,4-triazole —— C14H16N6S2
    4-Methyl-3-[[4-[(4-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]methylsulfanyl]-1,2,4-triazole
    —— ethyl 2,4-dimethyl-5-[(2R)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]-1H-pyrrole-3-carboxylate —— C15H20N4O3S
    ethyl 2,4-dimethyl-5-[(2R)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]propanoyl]-1H-pyrrole-3-carboxylate
    —— [(1S)-3-methyl-1-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]butyl]azanium —— C15H22N3OS+
    [(1S)-3-methyl-1-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]butyl]azanium
    —— 1-[(3R)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone —— C18H16ClN5O2S
    1-[(3R)-5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone
    —— N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H15ClN4OS
    N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 3-butyl-5-[(1S)-1-[[4-(2-thiophen-2-ylethyl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4-oxadiazole —— C16H21N5OS2
    3-butyl-5-[(1S)-1-[[4-(2-thiophen-2-ylethyl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4-oxadiazole
    —— 1-[(3R)-3-(furan-2-yl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone —— C19H19N5O2S
    1-[(3R)-3-(furan-2-yl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone
    —— N-(1-cyanocyclohexyl)-N-methyl-2-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H19N5OS
    N-(1-cyanocyclohexyl)-N-methyl-2-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— N-[(2R)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C13H22N4O3S2
    N-[(2R)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— (3S)-N-[4-(4,6-dimethylpyrimidin-2-yl)sulfanylphenyl]-1-(furan-2-ylmethyl)-5-oxopyrrolidine-3-carboxamide —— C22H22N4O3S
    (3S)-N-[4-(4,6-dimethylpyrimidin-2-yl)sulfanylphenyl]-1-(furan-2-ylmethyl)-5-oxopyrrolidine-3-carboxamide
    —— 3-butyl-5-[(1R)-1-[[4-(2-thiophen-2-ylethyl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4-oxadiazole —— C16H21N5OS2
    3-butyl-5-[(1R)-1-[[4-(2-thiophen-2-ylethyl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4-oxadiazole
    —— [(2R)-1-[di(propan-2-yl)amino]-1-oxopropan-2-yl] 2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetate —— C17H27N3O3S
    [(2R)-1-[di(propan-2-yl)amino]-1-oxopropan-2-yl] 2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetate
    —— 1-methyl-3-[2-[(1S,2R)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea —— C15H30N2O4S
    1-methyl-3-[2-[(1S,2R)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea
    —— [(2S)-1-[di(propan-2-yl)amino]-1-oxopropan-2-yl] 2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetate —— C17H27N3O3S
    [(2S)-1-[di(propan-2-yl)amino]-1-oxopropan-2-yl] 2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetate
    —— 1-methyl-3-[2-[(1R,2R)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea —— C15H30N2O4S
    1-methyl-3-[2-[(1R,2R)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea
    —— 1-methyl-3-[2-[(1S,2S)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea —— C15H30N2O4S
    1-methyl-3-[2-[(1S,2S)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea
    —— 1-methyl-3-[2-[(1R,2S)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea —— C15H30N2O4S
    1-methyl-3-[2-[(1R,2S)-2-methylcyclohexyl]oxyethyl]-1-[(2S)-1-methylsulfonylpropan-2-yl]urea
    —— (2S)-2-[[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]sulfanylmethyl]-4-propan-2-ylmorpholine —— C14H25N5O2S
    (2S)-2-[[1-[[(2S)-oxolan-2-yl]methyl]tetrazol-5-yl]sulfanylmethyl]-4-propan-2-ylmorpholine