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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[2-[[5-(benzylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethyl]acetamide —— C13H16N4OS2
    N-[2-[[5-(benzylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethyl]acetamide
    —— 2-[2-(3-chlorophenyl)-6-propylpyrimidin-4-yl]sulfanylacetic acid —— C15H15ClN2O2S
    2-[2-(3-chlorophenyl)-6-propylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(4-chlorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C15H15ClN2O2S
    2-[2-(4-chlorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[5-ethyl-6-methyl-2-(4-methylphenyl)pyrimidin-4-yl]sulfanylacetic acid —— C16H18N2O2S
    2-[5-ethyl-6-methyl-2-(4-methylphenyl)pyrimidin-4-yl]sulfanylacetic acid
    —— N-benzyl-5-[[(1R)-2,2-dichlorocyclopropyl]methylsulfanyl]-1,3,4-thiadiazol-2-amine —— C13H13Cl2N3S2
    N-benzyl-5-[[(1R)-2,2-dichlorocyclopropyl]methylsulfanyl]-1,3,4-thiadiazol-2-amine
    —— 2-[2-(2-fluorophenyl)-6-pyridin-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C17H12FN3O2S
    2-[2-(2-fluorophenyl)-6-pyridin-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(2-fluorophenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid —— C17H12FN3O2S
    2-[2-(2-fluorophenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3,5-dimethylpyrazol-1-yl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid —— C16H15N5O2S
    2-[2-(3,5-dimethylpyrazol-1-yl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(4-methylphenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C16H18N2O2S
    2-[2-(4-methylphenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-Fluorophenyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid —— C13H11FN2O2S
    2-[2-(3-Fluorophenyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-fluorophenyl)-6-pyridin-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C17H12FN3O2S
    2-[2-(3-fluorophenyl)-6-pyridin-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— N-benzyl-5-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,3,4-thiadiazol-2-amine —— C16H13N5OS3
    N-benzyl-5-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,3,4-thiadiazol-2-amine
    —— 2-[2-(2-fluorophenyl)-6-(methoxymethyl)pyrimidin-4-yl]sulfanylacetic acid —— C14H13FN2O3S
    2-[2-(2-fluorophenyl)-6-(methoxymethyl)pyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-chlorophenyl)-6-ethylpyrimidin-4-yl]sulfanylacetic acid —— C14H13ClN2O2S
    2-[2-(3-chlorophenyl)-6-ethylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-(2-phenyl-6-propan-2-ylpyrimidin-4-yl)sulfanylacetic acid —— C15H16N2O2S
    2-(2-phenyl-6-propan-2-ylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-[2-(3-fluorophenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid —— C17H12FN3O2S
    2-[2-(3-fluorophenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(4-methylphenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid —— C18H15N3O2S
    2-[2-(4-methylphenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3,5-dimethylpyrazol-1-yl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C14H18N4O2S
    2-[2-(3,5-dimethylpyrazol-1-yl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-chlorophenyl)-6-ethyl-5-methylpyrimidin-4-yl]sulfanylacetic acid —— C15H15ClN2O2S
    2-[2-(3-chlorophenyl)-6-ethyl-5-methylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-Phenyl-5-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,3,4-oxadiazole —— C15H10N4O2S2
    2-Phenyl-5-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,3,4-oxadiazole
    —— 2-(5-ethyl-6-methyl-2-phenylpyrimidin-4-yl)sulfanylacetic acid —— C15H16N2O2S
    2-(5-ethyl-6-methyl-2-phenylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-[2-(2-fluorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C15H15FN2O2S
    2-[2-(2-fluorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[5-ethyl-2-(2-fluorophenyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid —— C15H15FN2O2S
    2-[5-ethyl-2-(2-fluorophenyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[6-ethyl-2-(2-fluorophenyl)pyrimidin-4-yl]sulfanylacetic acid —— C14H13FN2O2S
    2-[6-ethyl-2-(2-fluorophenyl)pyrimidin-4-yl]sulfanylacetic acid
    —— 2-(2-phenyl-6-pyridin-4-ylpyrimidin-4-yl)sulfanylacetic acid —— C17H13N3O2S
    2-(2-phenyl-6-pyridin-4-ylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-[2-(3-fluorophenyl)-6-propylpyrimidin-4-yl]sulfanylacetic acid —— C15H15FN2O2S
    2-[2-(3-fluorophenyl)-6-propylpyrimidin-4-yl]sulfanylacetic acid
    —— 3-Methyl-5-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,2,4-triazol-4-amine —— C10H10N6OS2
    3-Methyl-5-[(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)methylsulfanyl]-1,2,4-triazol-4-amine
    —— 2-[2-(3-fluorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C15H15FN2O2S
    2-[2-(3-fluorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-chlorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C15H15ClN2O2S
    2-[2-(3-chlorophenyl)-6-propan-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-(2-phenyl-6-pyridin-2-ylpyrimidin-4-yl)sulfanylacetic acid —— C17H13N3O2S
    2-(2-phenyl-6-pyridin-2-ylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-[2-(4-methylphenyl)-6-pyridin-2-ylpyrimidin-4-yl]sulfanylacetic acid —— C18H15N3O2S
    2-[2-(4-methylphenyl)-6-pyridin-2-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-fluorophenyl)-5,6-dimethylpyrimidin-4-yl]sulfanylacetic acid —— C14H13FN2O2S
    2-[2-(3-fluorophenyl)-5,6-dimethylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[6-ethyl-2-(4-methylphenyl)pyrimidin-4-yl]sulfanylacetic acid —— C15H16N2O2S
    2-[6-ethyl-2-(4-methylphenyl)pyrimidin-4-yl]sulfanylacetic acid
    —— 2-[6-ethyl-2-(3-fluorophenyl)pyrimidin-4-yl]sulfanylacetic acid —— C14H13FN2O2S
    2-[6-ethyl-2-(3-fluorophenyl)pyrimidin-4-yl]sulfanylacetic acid
    —— 2-(6-ethyl-5-methyl-2-phenylpyrimidin-4-yl)sulfanylacetic acid —— C15H16N2O2S
    2-(6-ethyl-5-methyl-2-phenylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-[2-(2-fluorophenyl)-5,6-dimethylpyrimidin-4-yl]sulfanylacetic acid —— C14H13FN2O2S
    2-[2-(2-fluorophenyl)-5,6-dimethylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(2-fluorophenyl)-6-propylpyrimidin-4-yl]sulfanylacetic acid —— C15H15FN2O2S
    2-[2-(2-fluorophenyl)-6-propylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-chlorophenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid —— C17H12ClN3O2S
    2-[2-(3-chlorophenyl)-6-pyridin-4-ylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[5-ethyl-2-(3-fluorophenyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid —— C15H15FN2O2S
    2-[5-ethyl-2-(3-fluorophenyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(3-chlorophenyl)-5,6-dimethylpyrimidin-4-yl]sulfanylacetic acid —— C14H13ClN2O2S
    2-[2-(3-chlorophenyl)-5,6-dimethylpyrimidin-4-yl]sulfanylacetic acid
    —— 2-[2-(4-chlorophenyl)-6-(methoxymethyl)pyrimidin-4-yl]sulfanylacetic acid —— C14H13ClN2O3S
    2-[2-(4-chlorophenyl)-6-(methoxymethyl)pyrimidin-4-yl]sulfanylacetic acid
    —— 2-(6-propyl-2-pyrazin-2-ylpyrimidin-4-yl)sulfanylacetic acid —— C13H14N4O2S
    2-(6-propyl-2-pyrazin-2-ylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-(6-ethyl-2-phenylpyrimidin-4-yl)sulfanylacetic acid —— C14H14N2O2S
    2-(6-ethyl-2-phenylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-(2-pyrazin-2-yl-6-pyridin-4-ylpyrimidin-4-yl)sulfanylacetic acid —— C15H11N5O2S
    2-(2-pyrazin-2-yl-6-pyridin-4-ylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-(2-pyrazin-2-yl-6-pyridin-2-ylpyrimidin-4-yl)sulfanylacetic acid —— C15H11N5O2S
    2-(2-pyrazin-2-yl-6-pyridin-2-ylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-[2-(3-fluorophenyl)-6-(methoxymethyl)pyrimidin-4-yl]sulfanylacetic acid —— C14H13FN2O3S
    2-[2-(3-fluorophenyl)-6-(methoxymethyl)pyrimidin-4-yl]sulfanylacetic acid
    —— 2-[6-ethyl-5-methyl-2-(4-methylphenyl)pyrimidin-4-yl]sulfanylacetic acid —— C16H18N2O2S
    2-[6-ethyl-5-methyl-2-(4-methylphenyl)pyrimidin-4-yl]sulfanylacetic acid
    —— 2-(2-phenyl-6-propylpyrimidin-4-yl)sulfanylacetic acid —— C15H16N2O2S
    2-(2-phenyl-6-propylpyrimidin-4-yl)sulfanylacetic acid
    —— 2-[(4-Amino-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-6,7,8,9-tetrahydropyrimido[2,1-b][1,3]benzothiazol-4-one —— C14H16N6OS2
    2-[(4-Amino-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-6,7,8,9-tetrahydropyrimido[2,1-b][1,3]benzothiazol-4-one
    —— 3-[[5-(2,5-Dimethylfuran-3-yl)-1,3,4-oxadiazol-2-yl]methylsulfanyl]-5-methyl-1,2,4-triazol-4-amine —— C12H14N6O2S
    3-[[5-(2,5-Dimethylfuran-3-yl)-1,3,4-oxadiazol-2-yl]methylsulfanyl]-5-methyl-1,2,4-triazol-4-amine