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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-1-amino-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol —— C9H16N4OS
    (2S)-1-amino-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol
    —— (2R)-1-amino-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol —— C12H16N4OS
    (2R)-1-amino-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol
    —— (2R)-1-amino-3-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol —— C13H18N4OS
    (2R)-1-amino-3-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol
    —— (2R)-1-amino-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol —— C7H14N4OS
    (2R)-1-amino-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propan-2-ol
    —— N-(cyclohexen-1-yl)-N-ethyl-2-[[4-(2-methylphenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide —— C19H23N3OS3
    N-(cyclohexen-1-yl)-N-ethyl-2-[[4-(2-methylphenyl)-5-sulfanylidene-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
    —— ethyl (2R)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoate —— C11H17N3O3S
    ethyl (2R)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoate
    —— ethyl (2S)-2-hydroxy-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propanoate —— C9H15N3O3S
    ethyl (2S)-2-hydroxy-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propanoate
    —— N-(cyclohexen-1-yl)-N-cyclopropyl-2-[[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C19H20FN3O2S
    N-(cyclohexen-1-yl)-N-cyclopropyl-2-[[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— ethyl (2S)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoate —— C11H17N3O3S
    ethyl (2S)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoate
    —— ethyl (2R)-2-hydroxy-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propanoate —— C9H15N3O3S
    ethyl (2R)-2-hydroxy-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propanoate
    —— [2-Oxo-2-(2-phenylethylamino)ethyl] 2-(4-bromophenyl)sulfanylacetate —— C18H18BrNO3S
    [2-Oxo-2-(2-phenylethylamino)ethyl] 2-(4-bromophenyl)sulfanylacetate
    —— [2-[[(2R)-butan-2-yl]amino]-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate —— C14H18BrNO3S
    [2-[[(2R)-butan-2-yl]amino]-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2S)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C16H20BrNO3S
    [(2S)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2R)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C16H20BrNO3S
    [(2R)-1-(cyclopentylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [2-(2-Cyanoethylamino)-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate —— C13H13BrN2O3S
    [2-(2-Cyanoethylamino)-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2R)-1-(furan-2-ylmethylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C16H16BrNO4S
    [(2R)-1-(furan-2-ylmethylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [2-oxo-2-[[(2S)-oxolan-2-yl]methylamino]ethyl] 2-(4-bromophenyl)sulfanylacetate —— C15H18BrNO4S
    [2-oxo-2-[[(2S)-oxolan-2-yl]methylamino]ethyl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2S)-1-(cyclopropylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C14H16BrNO3S
    [(2S)-1-(cyclopropylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [2-oxo-2-[[(2R)-oxolan-2-yl]methylamino]ethyl] 2-(4-bromophenyl)sulfanylacetate —— C15H18BrNO4S
    [2-oxo-2-[[(2R)-oxolan-2-yl]methylamino]ethyl] 2-(4-bromophenyl)sulfanylacetate
    —— [5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl]methyl 2-(4-bromophenyl)sulfanylacetate —— C15H11BrN2O4S
    [5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl]methyl 2-(4-bromophenyl)sulfanylacetate
    —— [(2R)-1-(cyclopropylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C14H16BrNO3S
    [(2R)-1-(cyclopropylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [2-[(4-Methylcyclohexyl)amino]-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate —— C17H22BrNO3S
    [2-[(4-Methylcyclohexyl)amino]-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate
    —— (2R)-3-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid —— C13H15N3O3S
    (2R)-3-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid
    —— (5-Phenyl-1,3,4-oxadiazol-2-yl)methyl 2-(4-bromophenyl)sulfanylacetate —— C17H13BrN2O3S
    (5-Phenyl-1,3,4-oxadiazol-2-yl)methyl 2-(4-bromophenyl)sulfanylacetate
    —— [(2S)-1-(furan-2-ylmethylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C16H16BrNO4S
    [(2S)-1-(furan-2-ylmethylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— (2S)-2-hydroxy-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid —— C12H13N3O3S
    (2S)-2-hydroxy-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid
    —— [2-[(4-Fluorophenyl)methylamino]-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate —— C17H15BrFNO3S
    [2-[(4-Fluorophenyl)methylamino]-2-oxoethyl] 2-(4-bromophenyl)sulfanylacetate
    —— (2S)-3-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid —— C13H15N3O3S
    (2S)-3-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid
    —— (2R)-2-hydroxy-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid —— C12H13N3O3S
    (2R)-2-hydroxy-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid
    —— (2S)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid —— C9H13N3O3S
    (2S)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid
    —— (2R)-2-hydroxy-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propanoic acid —— C7H11N3O3S
    (2R)-2-hydroxy-3-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)propanoic acid
    —— (2R)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid —— C9H13N3O3S
    (2R)-3-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxypropanoic acid
    —— (2R)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetic acid —— C11H11N3O3S
    (2R)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetic acid
    —— (2R)-2-hydroxy-2-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)acetic acid —— C6H9N3O3S
    (2R)-2-hydroxy-2-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)acetic acid
    —— (2R)-2-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetic acid —— C12H13N3O3S
    (2R)-2-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetic acid
    —— (2S)-2-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetic acid —— C12H13N3O3S
    (2S)-2-(4-benzyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetic acid
    —— (2S)-2-hydroxy-2-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)acetic acid —— C6H9N3O3S
    (2S)-2-hydroxy-2-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)acetic acid
    —— (2S)-2-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetic acid —— C8H11N3O3S
    (2S)-2-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetic acid
    —— [2-Oxo-2-(2-phenylsulfanylanilino)ethyl] 4-(hydroxymethyl)benzoate —— C22H19NO4S
    [2-Oxo-2-(2-phenylsulfanylanilino)ethyl] 4-(hydroxymethyl)benzoate
    —— (2S)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetic acid —— C11H11N3O3S
    (2S)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetic acid
    —— ethyl (2S)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetate —— C13H15N3O3S
    ethyl (2S)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetate
    —— ethyl (2S)-2-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetate —— C10H15N3O3S
    ethyl (2S)-2-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetate
    —— ethyl (2R)-2-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetate —— C10H15N3O3S
    ethyl (2R)-2-(4-cyclopropyl-5-methylsulfanyl-1,2,4-triazol-3-yl)-2-hydroxyacetate
    —— ethyl (2S)-2-hydroxy-2-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)acetate —— C8H13N3O3S
    ethyl (2S)-2-hydroxy-2-(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)acetate
    —— ethyl (2R)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetate —— C13H15N3O3S
    ethyl (2R)-2-hydroxy-2-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)acetate
    —— 2-[[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(1R)-3-methyl-1-phenylbutyl]acetamide —— C21H22FN3O2S
    2-[[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-[(1R)-3-methyl-1-phenylbutyl]acetamide
    —— (2R)-2-amino-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid —— C12H14N4O2S
    (2R)-2-amino-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid
    —— (2S)-2-amino-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid —— C12H14N4O2S
    (2S)-2-amino-3-(4-methyl-5-phenylsulfanyl-1,2,4-triazol-3-yl)propanoic acid
    —— N-[(1R)-3-methyl-1-phenylbutyl]-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide —— C20H22N4O2S
    N-[(1R)-3-methyl-1-phenylbutyl]-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide
    —— N-methyl-N-(4-methylcyclohexyl)-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C15H26N4O2S
    N-methyl-N-(4-methylcyclohexyl)-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide