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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[2-(3-chlorophenyl)ethyl]-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C15H19ClN4O2S
    N-[2-(3-chlorophenyl)ethyl]-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— N-(1-adamantyl)-N-(2-cyanoethyl)-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C20H29N5O2S
    N-(1-adamantyl)-N-(2-cyanoethyl)-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— N-[(3-chlorophenyl)methyl]-N-methyl-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C15H19ClN4O2S
    N-[(3-chlorophenyl)methyl]-N-methyl-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— N-[(4-ethylphenyl)methyl]-N-methyl-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C17H24N4O2S
    N-[(4-ethylphenyl)methyl]-N-methyl-2-[(5-oxo-4-propyl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— (1R)-N-[(1R,3S)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide —— C14H23NO3S
    (1R)-N-[(1R,3S)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide
    —— (1R)-N-[(1S,3R)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide —— C14H23NO3S
    (1R)-N-[(1S,3R)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide
    —— (1R)-N-[(1R,3R)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide —— C14H23NO3S
    (1R)-N-[(1R,3R)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide
    —— (1R)-N-[(1S,3S)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide —— C14H23NO3S
    (1R)-N-[(1S,3S)-3-methylsulfonylcyclohexyl]cyclohex-3-ene-1-carboxamide
    —— 2-(cyclohexen-1-yl)-N-[(1R,3S)-3-methylsulfonylcyclohexyl]acetamide —— C15H25NO3S
    2-(cyclohexen-1-yl)-N-[(1R,3S)-3-methylsulfonylcyclohexyl]acetamide
    —— 2-(cyclohexen-1-yl)-N-[(1S,3S)-3-methylsulfonylcyclohexyl]acetamide —— C15H25NO3S
    2-(cyclohexen-1-yl)-N-[(1S,3S)-3-methylsulfonylcyclohexyl]acetamide
    —— 2-(cyclohexen-1-yl)-N-[(1S,3R)-3-methylsulfonylcyclohexyl]acetamide —— C15H25NO3S
    2-(cyclohexen-1-yl)-N-[(1S,3R)-3-methylsulfonylcyclohexyl]acetamide
    —— 2-(cyclohexen-1-yl)-N-[(1R,3R)-3-methylsulfonylcyclohexyl]acetamide —— C15H25NO3S
    2-(cyclohexen-1-yl)-N-[(1R,3R)-3-methylsulfonylcyclohexyl]acetamide
    —— 2-[[5,6-bis(4-methylphenyl)-1,2,4-triazin-3-yl]sulfanyl]-N-[(1R)-1-cyclopropylethyl]acetamide —— C24H26N4OS
    2-[[5,6-bis(4-methylphenyl)-1,2,4-triazin-3-yl]sulfanyl]-N-[(1R)-1-cyclopropylethyl]acetamide
    —— 5,6-Bis(4-methylphenyl)-3-[(1-propyltetrazol-5-yl)methylsulfanyl]-1,2,4-triazine —— C22H23N7S
    5,6-Bis(4-methylphenyl)-3-[(1-propyltetrazol-5-yl)methylsulfanyl]-1,2,4-triazine
    —— [(2S)-1-oxo-1-(2-phenylsulfanylanilino)propan-2-yl] 2,4-dimethyl-1,3-thiazole-5-carboxylate —— C21H20N2O3S2
    [(2S)-1-oxo-1-(2-phenylsulfanylanilino)propan-2-yl] 2,4-dimethyl-1,3-thiazole-5-carboxylate
    —— [(2R)-1-oxo-1-(2-phenylsulfanylanilino)propan-2-yl] 2,4-dimethyl-1,3-thiazole-5-carboxylate —— C21H20N2O3S2
    [(2R)-1-oxo-1-(2-phenylsulfanylanilino)propan-2-yl] 2,4-dimethyl-1,3-thiazole-5-carboxylate
    —— [2-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-oxoethyl] 3-(4-chlorophenyl)sulfanylpropanoate —— C20H19ClO5S
    [2-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-2-oxoethyl] 3-(4-chlorophenyl)sulfanylpropanoate
    —— methyl (2S)-2-(4-cyclopentylsulfanylphenyl)-2-hydroxyacetate —— C14H18O3S
    methyl (2S)-2-(4-cyclopentylsulfanylphenyl)-2-hydroxyacetate
    —— [2-[(2-Methylphenyl)methylamino]-2-oxoethyl] 3-(4-chlorophenyl)sulfanylpropanoate —— C19H20ClNO3S
    [2-[(2-Methylphenyl)methylamino]-2-oxoethyl] 3-(4-chlorophenyl)sulfanylpropanoate
    —— methyl (2R)-2-(4-cyclopentylsulfanylphenyl)-2-hydroxyacetate —— C14H18O3S
    methyl (2R)-2-(4-cyclopentylsulfanylphenyl)-2-hydroxyacetate
    —— [2-[[(1S)-1-(furan-2-yl)ethyl]amino]-2-oxoethyl] 3-(4-chlorophenyl)sulfanylpropanoate —— C17H18ClNO4S
    [2-[[(1S)-1-(furan-2-yl)ethyl]amino]-2-oxoethyl] 3-(4-chlorophenyl)sulfanylpropanoate
    —— (2R)-2-(4-cyclopentylsulfanylphenyl)-1-methoxypropan-2-amine —— C15H23NOS
    (2R)-2-(4-cyclopentylsulfanylphenyl)-1-methoxypropan-2-amine
    —— (2S)-2-(4-cyclopentylsulfanylphenyl)-1-methoxypropan-2-amine —— C15H23NOS
    (2S)-2-(4-cyclopentylsulfanylphenyl)-1-methoxypropan-2-amine
    —— 4-[2-(4-ethylsulfanylphenyl)ethyl]-1H-1,2,4-triazole-5-thione —— C12H15N3S2
    4-[2-(4-ethylsulfanylphenyl)ethyl]-1H-1,2,4-triazole-5-thione
    —— (R)-(4-ethylsulfanylphenyl)-(1-methylpiperidin-4-yl)methanamine —— C15H24N2S
    (R)-(4-ethylsulfanylphenyl)-(1-methylpiperidin-4-yl)methanamine
    —— (4S)-4-(aminomethyl)-1-[2-(4-methylsulfanylphenyl)ethyl]pyrrolidin-2-one —— C14H20N2OS
    (4S)-4-(aminomethyl)-1-[2-(4-methylsulfanylphenyl)ethyl]pyrrolidin-2-one
    —— (2S)-2-(1-methylpiperidin-4-yl)-2-(4-methylsulfanylphenyl)ethanamine —— C15H24N2S
    (2S)-2-(1-methylpiperidin-4-yl)-2-(4-methylsulfanylphenyl)ethanamine
    —— 2-O-ethyl 4-O-[2-[methyl-[(4-methylsulfanylphenyl)methyl]amino]-2-oxoethyl] 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate —— C21H26N2O5S
    2-O-ethyl 4-O-[2-[methyl-[(4-methylsulfanylphenyl)methyl]amino]-2-oxoethyl] 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate
    —— (S)-(4-ethylsulfanylphenyl)-(1-methylpiperidin-4-yl)methanamine —— C15H24N2S
    (S)-(4-ethylsulfanylphenyl)-(1-methylpiperidin-4-yl)methanamine
    —— (2R)-2-(1-methylpiperidin-4-yl)-2-(4-methylsulfanylphenyl)ethanamine —— C15H24N2S
    (2R)-2-(1-methylpiperidin-4-yl)-2-(4-methylsulfanylphenyl)ethanamine
    —— (4S)-4-(aminomethyl)-1-[(4-ethylsulfanylphenyl)methyl]pyrrolidin-2-one —— C14H20N2OS
    (4S)-4-(aminomethyl)-1-[(4-ethylsulfanylphenyl)methyl]pyrrolidin-2-one
    —— (4R)-4-(aminomethyl)-1-[2-(4-methylsulfanylphenyl)ethyl]pyrrolidin-2-one —— C14H20N2OS
    (4R)-4-(aminomethyl)-1-[2-(4-methylsulfanylphenyl)ethyl]pyrrolidin-2-one
    —— (4R)-4-(aminomethyl)-1-[(4-ethylsulfanylphenyl)methyl]pyrrolidin-2-one —— C14H20N2OS
    (4R)-4-(aminomethyl)-1-[(4-ethylsulfanylphenyl)methyl]pyrrolidin-2-one
    —— 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-propan-2-yloxypropyl)acetamide —— C16H24N4O2S2
    2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-propan-2-yloxypropyl)acetamide
    —— 2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-cyanopropan-2-yl)-N-methylacetamide —— C20H21N5OS2
    2-[(4-benzyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-cyanopropan-2-yl)-N-methylacetamide
    —— 2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(2R)-heptan-2-yl]acetamide —— C22H28N4O2S
    2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(2R)-heptan-2-yl]acetamide
    —— 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2S)-5-methylhexan-2-yl]acetamide —— C17H26N4OS2
    2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2S)-5-methylhexan-2-yl]acetamide
    —— 2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(3-propan-2-yloxypropyl)acetamide —— C21H26N4O3S
    2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(3-propan-2-yloxypropyl)acetamide
    —— 2-[5-(4-propan-2-ylsulfanylphenyl)-1,3,4-oxadiazol-2-yl]ethanol —— C13H16N2O2S
    2-[5-(4-propan-2-ylsulfanylphenyl)-1,3,4-oxadiazol-2-yl]ethanol
    —— 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methylbutan-2-yl)acetamide —— C15H22N4OS2
    2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methylbutan-2-yl)acetamide
    —— N-[(1R)-1-cyclopropylethyl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C15H20N4OS2
    N-[(1R)-1-cyclopropylethyl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-hexylacetamide —— C16H24N4OS2
    2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-hexylacetamide
    —— N-[2-(3-chlorophenyl)ethyl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide —— C18H19ClN4OS2
    N-[2-(3-chlorophenyl)ethyl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
    —— 2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-cyclopropylethyl]acetamide —— C20H22N4O2S
    2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(1S)-1-cyclopropylethyl]acetamide
    —— 3-[[4-Benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]-5-phenyl-1,2-oxazole —— C23H18N4O2S
    3-[[4-Benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]-5-phenyl-1,2-oxazole
    —— N-[(3-chlorophenyl)methyl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylacetamide —— C18H19ClN4OS2
    N-[(3-chlorophenyl)methyl]-2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-methylacetamide
    —— 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-6-methylheptan-2-yl]acetamide —— C18H28N4OS2
    2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(2R)-6-methylheptan-2-yl]acetamide
    —— 2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[2-(2-fluorophenyl)ethyl]acetamide —— C18H19FN4OS2
    2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[2-(2-fluorophenyl)ethyl]acetamide
    —— 1-(Azocan-1-yl)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]ethanone —— C22H26N4O2S
    1-(Azocan-1-yl)-2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]ethanone
    —— 2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-hexylacetamide —— C21H26N4O2S
    2-[[4-benzyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-hexylacetamide