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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-[(2S)-2-phenylsulfanylpropyl]-3-[(1R)-1-pyridin-4-ylethyl]urea —— C17H21N3OS
    1-[(2S)-2-phenylsulfanylpropyl]-3-[(1R)-1-pyridin-4-ylethyl]urea
    —— 1-[(2R)-2-phenylsulfanylpropyl]-3-[(1R)-1-pyridin-4-ylethyl]urea —— C17H21N3OS
    1-[(2R)-2-phenylsulfanylpropyl]-3-[(1R)-1-pyridin-4-ylethyl]urea
    —— 1-[(1-methylpyrazol-4-yl)methyl]-3-[(2S)-2-phenylsulfanylpropyl]urea —— C15H20N4OS
    1-[(1-methylpyrazol-4-yl)methyl]-3-[(2S)-2-phenylsulfanylpropyl]urea
    —— 1-[(1-methylpyrazol-4-yl)methyl]-3-[(2R)-2-phenylsulfanylpropyl]urea —— C15H20N4OS
    1-[(1-methylpyrazol-4-yl)methyl]-3-[(2R)-2-phenylsulfanylpropyl]urea
    —— 1-[(2S)-2-phenylsulfanylpropyl]-3-[(1S)-1-pyridin-4-ylethyl]urea —— C17H21N3OS
    1-[(2S)-2-phenylsulfanylpropyl]-3-[(1S)-1-pyridin-4-ylethyl]urea
    —— 1-[(5-methyl-1,2-oxazol-3-yl)methyl]-3-[(2R)-2-phenylsulfanylpropyl]urea —— C15H19N3O2S
    1-[(5-methyl-1,2-oxazol-3-yl)methyl]-3-[(2R)-2-phenylsulfanylpropyl]urea
    —— 3-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]-5-[(2S)-oxan-2-yl]-1,2,4-triazol-4-amine —— C13H19N5O2S
    3-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]-5-[(2S)-oxan-2-yl]-1,2,4-triazol-4-amine
    —— 3-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]-5-[(2R)-oxan-2-yl]-1,2,4-triazol-4-amine —— C13H19N5O2S
    3-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]-5-[(2R)-oxan-2-yl]-1,2,4-triazol-4-amine
    —— (2R)-1-(3-methylphenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol —— C13H15N3O3S
    (2R)-1-(3-methylphenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol
    —— (2S)-1-(3-methylphenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol —— C13H15N3O3S
    (2S)-1-(3-methylphenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol
    —— (2S)-1-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]-3-(4-nitropyrazol-1-yl)propan-2-ol —— C10H12N4O3S2
    (2S)-1-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]-3-(4-nitropyrazol-1-yl)propan-2-ol
    —— (2R)-1-(4-chlorophenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol —— C12H12ClN3O3S
    (2R)-1-(4-chlorophenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol
    —— (1S)-2-(1-methylimidazol-2-yl)sulfanyl-1-(2-methylphenyl)ethanol —— C13H16N2OS
    (1S)-2-(1-methylimidazol-2-yl)sulfanyl-1-(2-methylphenyl)ethanol
    —— (1R)-2-(1-methylimidazol-2-yl)sulfanyl-1-(2-methylphenyl)ethanol —— C13H16N2OS
    (1R)-2-(1-methylimidazol-2-yl)sulfanyl-1-(2-methylphenyl)ethanol
    —— (2S)-1-(4-chlorophenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol —— C12H12ClN3O3S
    (2S)-1-(4-chlorophenyl)sulfanyl-3-(4-nitropyrazol-1-yl)propan-2-ol
    —— (1R,3R)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine —— C11H23NO2S2
    (1R,3R)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine
    —— (1R,3S)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine —— C11H23NO2S2
    (1R,3S)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine
    —— (1S,3R)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine —— C11H23NO2S2
    (1S,3R)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine
    —— (1S,3S)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine —— C11H23NO2S2
    (1S,3S)-3-ethylsulfanyl-N-methyl-N-(2-methylsulfonylethyl)cyclopentan-1-amine
    —— 1-(1-methylpyrazol-3-yl)-3-[(2R)-2-phenylsulfanylpropyl]urea —— C14H18N4OS
    1-(1-methylpyrazol-3-yl)-3-[(2R)-2-phenylsulfanylpropyl]urea
    —— 1-(1-methylpyrazol-4-yl)-3-[(2R)-2-phenylsulfanylpropyl]urea —— C14H18N4OS
    1-(1-methylpyrazol-4-yl)-3-[(2R)-2-phenylsulfanylpropyl]urea
    —— 1-(1-methylpyrazol-4-yl)-3-[(2S)-2-phenylsulfanylpropyl]urea —— C14H18N4OS
    1-(1-methylpyrazol-4-yl)-3-[(2S)-2-phenylsulfanylpropyl]urea
    —— 2-(4-fluorophenyl)sulfanyl-1-[(3R)-3-(5-methylfuran-2-yl)thiomorpholin-4-yl]ethanone —— C17H18FNO2S2
    2-(4-fluorophenyl)sulfanyl-1-[(3R)-3-(5-methylfuran-2-yl)thiomorpholin-4-yl]ethanone
    —— (1,3-dimethylpyrazol-4-yl)-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]methanone —— C17H21N3OS
    (1,3-dimethylpyrazol-4-yl)-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]methanone
    —— 2-ethoxy-1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]ethanone —— C15H21NO2S
    2-ethoxy-1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]ethanone
    —— 1-[(3R)-3-(5-methylfuran-2-yl)thiomorpholin-4-yl]-2-pyridin-4-ylsulfanylethanone —— C16H18N2O2S2
    1-[(3R)-3-(5-methylfuran-2-yl)thiomorpholin-4-yl]-2-pyridin-4-ylsulfanylethanone
    —— 2-(4-fluorophenyl)sulfanyl-1-[(3S)-3-(5-methylfuran-2-yl)thiomorpholin-4-yl]ethanone —— C17H18FNO2S2
    2-(4-fluorophenyl)sulfanyl-1-[(3S)-3-(5-methylfuran-2-yl)thiomorpholin-4-yl]ethanone
    —— (E)-1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-3-ylprop-2-en-1-one —— C19H20N2OS
    (E)-1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-3-ylprop-2-en-1-one
    —— (E)-1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-3-ylprop-2-en-1-one —— C19H20N2OS
    (E)-1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-3-ylprop-2-en-1-one
    —— 1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-2-ylpropan-1-one —— C19H22N2OS
    1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-2-ylpropan-1-one
    —— 1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-2-pyridin-4-ylsulfanylethanone —— C18H20N2OS2
    1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-2-pyridin-4-ylsulfanylethanone
    —— 1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-2-ylpropan-1-one —— C19H22N2OS
    1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-3-pyridin-2-ylpropan-1-one
    —— 2-ethoxy-1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]ethanone —— C15H21NO2S
    2-ethoxy-1-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]ethanone
    —— (1,3-dimethylpyrazol-4-yl)-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]methanone —— C17H21N3OS
    (1,3-dimethylpyrazol-4-yl)-[(3R)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]methanone
    —— N-[(1S)-2-ethyl-1-phenylbutyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide —— C18H25N3OS
    N-[(1S)-2-ethyl-1-phenylbutyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide
    —— 1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-2-pyridin-4-ylsulfanylethanone —— C18H20N2OS2
    1-[(3S)-3-(phenylsulfanylmethyl)pyrrolidin-1-yl]-2-pyridin-4-ylsulfanylethanone
    —— 1-[(2S)-2-phenylsulfanylpropyl]-3-(pyridin-3-ylmethyl)urea —— C16H19N3OS
    1-[(2S)-2-phenylsulfanylpropyl]-3-(pyridin-3-ylmethyl)urea
    —— 1-[(2R)-2-phenylsulfanylpropyl]-3-(pyridin-3-ylmethyl)urea —— C16H19N3OS
    1-[(2R)-2-phenylsulfanylpropyl]-3-(pyridin-3-ylmethyl)urea
    —— N-[(1R)-2-ethyl-1-phenylbutyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide —— C18H25N3OS
    N-[(1R)-2-ethyl-1-phenylbutyl]-2-(1-methylimidazol-2-yl)sulfanylacetamide
    —— N-cyclopentyl-2-[(2R,3S)-3-hydroxybutan-2-yl]sulfonylacetamide —— C11H21NO4S
    N-cyclopentyl-2-[(2R,3S)-3-hydroxybutan-2-yl]sulfonylacetamide
    —— N-cyclopentyl-2-[(2S,3S)-3-hydroxybutan-2-yl]sulfonylacetamide —— C11H21NO4S
    N-cyclopentyl-2-[(2S,3S)-3-hydroxybutan-2-yl]sulfonylacetamide
    —— (3S)-3-[(4-amino-5-butyl-1,2,4-triazol-3-yl)sulfanyl]-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one —— C12H18F3N5OS
    (3S)-3-[(4-amino-5-butyl-1,2,4-triazol-3-yl)sulfanyl]-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one
    —— N-cyclopentyl-2-[(2S,3R)-3-hydroxybutan-2-yl]sulfonylacetamide —— C11H21NO4S
    N-cyclopentyl-2-[(2S,3R)-3-hydroxybutan-2-yl]sulfonylacetamide
    —— N-cyclopentyl-2-[(2R,3R)-3-hydroxybutan-2-yl]sulfonylacetamide —— C11H21NO4S
    N-cyclopentyl-2-[(2R,3R)-3-hydroxybutan-2-yl]sulfonylacetamide
    —— [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3R,4S)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone —— C18H24N2O3S
    [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3R,4S)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone
    —— [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3S,4R)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone —— C18H24N2O3S
    [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3S,4R)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone
    —— [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3R,4R)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone —— C18H24N2O3S
    [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3R,4R)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone
    —— [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3S,4S)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone —— C18H24N2O3S
    [(2R)-2,3-dihydro-1,4-benzoxathiin-2-yl]-[(3S,4S)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone
    —— [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3S,4S)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone —— C18H24N2O2S
    [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3S,4S)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone
    —— [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3R,4R)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone —— C18H24N2O2S
    [(3R)-2,3-dihydro-1-benzothiophen-3-yl]-[(3R,4R)-3-methyl-4-morpholin-4-ylpyrrolidin-1-yl]methanone