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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 4-[(4-Cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-(4-methylphenyl)-1,3-thiazole —— C17H18N4S2
    4-[(4-Cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-(4-methylphenyl)-1,3-thiazole
    —— 4-[(4-Cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-thiophen-2-yl-1,3-oxazole —— C14H14N4OS2
    4-[(4-Cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-thiophen-2-yl-1,3-oxazole
    —— (2R)-N-benzyl-2-[(4-cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C16H20N4OS
    (2R)-N-benzyl-2-[(4-cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— 4-[(4-Cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-(4-fluorophenyl)-1,3-thiazole —— C16H15FN4S2
    4-[(4-Cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanylmethyl]-2-(4-fluorophenyl)-1,3-thiazole
    —— 2-[(4-cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(4-fluorophenyl)methyl]acetamide —— C15H17FN4OS
    2-[(4-cyclopropyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-[(4-fluorophenyl)methyl]acetamide
    —— [(2S)-1-(ethylamino)-1-oxopropan-2-yl] (1'S,5'R)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate —— C17H27NO3S2
    [(2S)-1-(ethylamino)-1-oxopropan-2-yl] (1'S,5'R)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate
    —— [(2R)-1-(ethylamino)-1-oxopropan-2-yl] (1'S,5'R)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate —— C17H27NO3S2
    [(2R)-1-(ethylamino)-1-oxopropan-2-yl] (1'S,5'R)-spiro[1,3-dithiolane-2,9'-bicyclo[3.3.1]nonane]-3'-carboxylate
    —— 2-[4-(4-fluorophenyl)-3-oxopyrazin-2-yl]sulfanyl-N-[(4-methylphenyl)methyl]acetamide —— C20H18FN3O2S
    2-[4-(4-fluorophenyl)-3-oxopyrazin-2-yl]sulfanyl-N-[(4-methylphenyl)methyl]acetamide
    —— (3S)-3-(4-methylsulfanylphenyl)-4-morpholin-4-ylbutan-1-amine —— C15H24N2OS
    (3S)-3-(4-methylsulfanylphenyl)-4-morpholin-4-ylbutan-1-amine
    —— (3R)-3-(4-methylsulfanylphenyl)-4-morpholin-4-ylbutan-1-amine —— C15H24N2OS
    (3R)-3-(4-methylsulfanylphenyl)-4-morpholin-4-ylbutan-1-amine
    —— (3S)-3-(4-ethylsulfanylphenyl)-3-(oxan-4-yl)propan-1-amine —— C16H25NOS
    (3S)-3-(4-ethylsulfanylphenyl)-3-(oxan-4-yl)propan-1-amine
    —— (3R)-3-(4-ethylsulfanylphenyl)-3-(oxan-4-yl)propan-1-amine —— C16H25NOS
    (3R)-3-(4-ethylsulfanylphenyl)-3-(oxan-4-yl)propan-1-amine
    —— (2S)-2-(oxan-4-yl)-2-(4-propan-2-ylsulfanylphenyl)ethanamine —— C16H25NOS
    (2S)-2-(oxan-4-yl)-2-(4-propan-2-ylsulfanylphenyl)ethanamine
    —— N-[2-(4-chlorophenyl)sulfanylphenyl]-2-(2-methylpyridin-1-ium-1-yl)acetamide —— C20H18ClN2OS+
    N-[2-(4-chlorophenyl)sulfanylphenyl]-2-(2-methylpyridin-1-ium-1-yl)acetamide
    —— 2-(2-methylpyridin-1-ium-1-yl)-N-(2-phenylsulfanylphenyl)acetamide —— C20H19N2OS+
    2-(2-methylpyridin-1-ium-1-yl)-N-(2-phenylsulfanylphenyl)acetamide
    —— (2R)-2-(oxan-4-yl)-2-(4-propan-2-ylsulfanylphenyl)ethanamine —— C16H25NOS
    (2R)-2-(oxan-4-yl)-2-(4-propan-2-ylsulfanylphenyl)ethanamine
    —— (3S)-3-(4-methylsulfanylphenyl)-4-piperidin-1-ylbutan-1-amine —— C16H26N2S
    (3S)-3-(4-methylsulfanylphenyl)-4-piperidin-1-ylbutan-1-amine
    —— 1-[(1S)-3-methyl-1-(4-methylsulfanylphenyl)butyl]piperazine —— C16H26N2S
    1-[(1S)-3-methyl-1-(4-methylsulfanylphenyl)butyl]piperazine
    —— (3R)-3-(4-methylsulfanylphenyl)-4-piperidin-1-ylbutan-1-amine —— C16H26N2S
    (3R)-3-(4-methylsulfanylphenyl)-4-piperidin-1-ylbutan-1-amine
    —— 1-[(1R)-3-methyl-1-(4-methylsulfanylphenyl)butyl]piperazine —— C16H26N2S
    1-[(1R)-3-methyl-1-(4-methylsulfanylphenyl)butyl]piperazine
    —— (2R)-2-(4-propan-2-ylsulfanylphenyl)-2-thiophen-2-ylethanamine —— C15H19NS2
    (2R)-2-(4-propan-2-ylsulfanylphenyl)-2-thiophen-2-ylethanamine
    —— (3R)-3-(4-ethylsulfanylphenyl)-3-thiophen-2-ylpropan-1-amine —— C15H19NS2
    (3R)-3-(4-ethylsulfanylphenyl)-3-thiophen-2-ylpropan-1-amine
    —— (3S)-3-(4-ethylsulfanylphenyl)-3-thiophen-2-ylpropan-1-amine —— C15H19NS2
    (3S)-3-(4-ethylsulfanylphenyl)-3-thiophen-2-ylpropan-1-amine
    —— (3S)-3-cyclohexyl-3-(4-ethylsulfanylphenyl)propan-1-amine —— C17H27NS
    (3S)-3-cyclohexyl-3-(4-ethylsulfanylphenyl)propan-1-amine
    —— (3R)-3-cyclopentyl-3-(4-propan-2-ylsulfanylphenyl)propan-1-amine —— C17H27NS
    (3R)-3-cyclopentyl-3-(4-propan-2-ylsulfanylphenyl)propan-1-amine
    —— (3S)-3-cyclopentyl-3-(4-propan-2-ylsulfanylphenyl)propan-1-amine —— C17H27NS
    (3S)-3-cyclopentyl-3-(4-propan-2-ylsulfanylphenyl)propan-1-amine
    —— (2R)-2-(4-cyclopentylsulfanylphenyl)-4-methylpentan-1-amine —— C17H27NS
    (2R)-2-(4-cyclopentylsulfanylphenyl)-4-methylpentan-1-amine
    —— (2S)-2-(4-cyclopentylsulfanylphenyl)-4-methylpentan-1-amine —— C17H27NS
    (2S)-2-(4-cyclopentylsulfanylphenyl)-4-methylpentan-1-amine
    —— (2S)-2-(4-propan-2-ylsulfanylphenyl)-2-thiophen-2-ylethanamine —— C15H19NS2
    (2S)-2-(4-propan-2-ylsulfanylphenyl)-2-thiophen-2-ylethanamine
    —— 1-[(R)-cyclobutyl-(4-methylsulfanylphenyl)methyl]piperazine —— C16H24N2S
    1-[(R)-cyclobutyl-(4-methylsulfanylphenyl)methyl]piperazine
    —— 1-[(S)-cyclopropyl-(4-ethylsulfanylphenyl)methyl]piperazine —— C16H24N2S
    1-[(S)-cyclopropyl-(4-ethylsulfanylphenyl)methyl]piperazine
    —— 1-[(S)-cyclopropyl-(4-methylsulfanylphenyl)methyl]-1,4-diazepane —— C16H24N2S
    1-[(S)-cyclopropyl-(4-methylsulfanylphenyl)methyl]-1,4-diazepane
    —— 1-[(R)-cyclopropyl-(4-ethylsulfanylphenyl)methyl]piperazine —— C16H24N2S
    1-[(R)-cyclopropyl-(4-ethylsulfanylphenyl)methyl]piperazine
    —— 1-[(S)-cyclobutyl-(4-methylsulfanylphenyl)methyl]piperazine —— C16H24N2S
    1-[(S)-cyclobutyl-(4-methylsulfanylphenyl)methyl]piperazine
    —— 1-[(R)-cyclopropyl-(4-methylsulfanylphenyl)methyl]-1,4-diazepane —— C16H24N2S
    1-[(R)-cyclopropyl-(4-methylsulfanylphenyl)methyl]-1,4-diazepane
    —— N-cyclohexyl-2-(4-methylphenyl)sulfanylpyridine-3-carboxamide —— C19H22N2OS
    N-cyclohexyl-2-(4-methylphenyl)sulfanylpyridine-3-carboxamide
    —— (2R)-N-[(4-chlorophenyl)methyl]-2-phenylsulfanylpropanamide —— C16H16ClNOS
    (2R)-N-[(4-chlorophenyl)methyl]-2-phenylsulfanylpropanamide
    —— N-[(4-chlorophenyl)methyl]-2-(2-methylphenyl)sulfanylacetamide —— C16H16ClNOS
    N-[(4-chlorophenyl)methyl]-2-(2-methylphenyl)sulfanylacetamide
    —— 1-Benzylsulfonyl-4-[2-(4-fluorophenyl)sulfanylethyl]piperazine —— C19H23FN2O2S2
    1-Benzylsulfonyl-4-[2-(4-fluorophenyl)sulfanylethyl]piperazine
    —— 1-Benzylsulfonyl-4-[2-(2-fluorophenyl)sulfanylethyl]piperazine —— C19H23FN2O2S2
    1-Benzylsulfonyl-4-[2-(2-fluorophenyl)sulfanylethyl]piperazine
    —— 1-Benzylsulfonyl-4-[2-(2-fluorophenyl)sulfanylethyl]piperazin-4-ium —— C19H24FN2O2S2+
    1-Benzylsulfonyl-4-[2-(2-fluorophenyl)sulfanylethyl]piperazin-4-ium
    —— 1-Benzylsulfonyl-4-[2-(4-fluorophenyl)sulfanylethyl]piperazin-4-ium —— C19H24FN2O2S2+
    1-Benzylsulfonyl-4-[2-(4-fluorophenyl)sulfanylethyl]piperazin-4-ium
    —— 2-Ethylsulfanyl-5-methyl-1,3,4-oxadiazole —— C5H8N2OS
    2-Ethylsulfanyl-5-methyl-1,3,4-oxadiazole
    —— 2-(2,4-Dinitrophenyl)sulfanyl-5-ethyl-1,3,4-oxadiazole —— C10H8N4O5S
    2-(2,4-Dinitrophenyl)sulfanyl-5-ethyl-1,3,4-oxadiazole
    —— 2-(2,4-Dinitrophenyl)sulfanyl-5-propyl-1,3,4-oxadiazole —— C11H10N4O5S
    2-(2,4-Dinitrophenyl)sulfanyl-5-propyl-1,3,4-oxadiazole
    —— 2-[(4-Chlorophenyl)methylsulfanyl]-5-propyl-1,3,4-oxadiazole —— C12H13ClN2OS
    2-[(4-Chlorophenyl)methylsulfanyl]-5-propyl-1,3,4-oxadiazole
    —— 2-[(4-Fluorophenyl)methylsulfanyl]-5-propyl-1,3,4-oxadiazole —— C12H13FN2OS
    2-[(4-Fluorophenyl)methylsulfanyl]-5-propyl-1,3,4-oxadiazole
    —— 2-(2,4-Dinitrophenyl)sulfanyl-5-methyl-1,3,4-oxadiazole —— C9H6N4O5S
    2-(2,4-Dinitrophenyl)sulfanyl-5-methyl-1,3,4-oxadiazole
    —— 4-Ethyl-3-ethylsulfanyl-5-propyl-1,2,4-triazole —— C9H17N3S
    4-Ethyl-3-ethylsulfanyl-5-propyl-1,2,4-triazole
    —— 2-[(4-Chlorobenzyl)sulfanyl]-5-ethyl-1,3,4-oxadiazole —— C11H11ClN2OS
    2-[(4-Chlorobenzyl)sulfanyl]-5-ethyl-1,3,4-oxadiazole