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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (2S)-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide —— C14H18FNO3S2
    (2S)-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide
    —— (2S)-N-[(2-chlorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide —— C16H15ClFNOS
    (2S)-N-[(2-chlorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide
    —— (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanylpropanamide —— C13H16FNO3S2
    (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanylpropanamide
    —— (2R)-N-[(2-chlorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide —— C16H15ClFNOS
    (2R)-N-[(2-chlorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide
    —— (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanylpropanamide —— C13H16FNO3S2
    (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanylpropanamide
    —— (2S)-N-(1-cyanocyclohexyl)-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide —— C17H21FN2OS
    (2S)-N-(1-cyanocyclohexyl)-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide
    —— (2R)-N-(1-cyanocyclohexyl)-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide —— C17H21FN2OS
    (2R)-N-(1-cyanocyclohexyl)-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide
    —— (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide —— C14H18FNO3S2
    (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide
    —— (2S)-N-[(4-fluorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide —— C16H15F2NOS
    (2S)-N-[(4-fluorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide
    —— (2R)-N-[(4-fluorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide —— C16H15F2NOS
    (2R)-N-[(4-fluorophenyl)methyl]-2-(4-fluorophenyl)sulfanylpropanamide
    —— (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide —— C14H18FNO3S2
    (2S)-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanyl-N-methylpropanamide
    —— (2R)-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanylpropanamide —— C13H16FNO3S2
    (2R)-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4-fluorophenyl)sulfanylpropanamide
    —— (2S)-N-[(4-methylphenyl)methyl]-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C16H20N4OS
    (2S)-N-[(4-methylphenyl)methyl]-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2S)-N-[(4-fluorophenyl)methyl]-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C15H17FN4OS
    (2S)-N-[(4-fluorophenyl)methyl]-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2R)-N-(2-phenylsulfanylphenyl)-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide —— C20H20N4OS2
    (2R)-N-(2-phenylsulfanylphenyl)-2-[(4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]propanamide
    —— (2R)-N-(1-cyanocyclohexyl)-2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide —— C22H33N5OS
    (2R)-N-(1-cyanocyclohexyl)-2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide
    —— (2R)-2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-phenylethyl)propanamide —— C22H30N4OS
    (2R)-2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-phenylethyl)propanamide
    —— (2S)-N-(1-cyanocyclohexyl)-2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide —— C22H33N5OS
    (2S)-N-(1-cyanocyclohexyl)-2-[(5-cyclohexyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]-N-methylpropanamide
    —— [(2R)-1-oxo-1-(2-phenylsulfanylanilino)propan-2-yl] 4-(hydroxymethyl)benzoate —— C23H21NO4S
    [(2R)-1-oxo-1-(2-phenylsulfanylanilino)propan-2-yl] 4-(hydroxymethyl)benzoate
    —— (2R)-2-(4-cyclopentylsulfanylphenyl)-2-(furan-2-yl)ethanamine —— C17H21NOS
    (2R)-2-(4-cyclopentylsulfanylphenyl)-2-(furan-2-yl)ethanamine
    —— (2R)-2-(3,4-dimethylphenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethylpropanamide —— C17H25NO3S2
    (2R)-2-(3,4-dimethylphenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethylpropanamide
    —— (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)propanamide —— C15H18BrN3O2S
    (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)propanamide
    —— (2S)-2-(4-cyclopentylsulfanylphenyl)-2-(furan-2-yl)ethanamine —— C17H21NOS
    (2S)-2-(4-cyclopentylsulfanylphenyl)-2-(furan-2-yl)ethanamine
    —— (2S)-2-(3,4-dimethylphenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]propanamide —— C15H21NO3S2
    (2S)-2-(3,4-dimethylphenyl)sulfanyl-N-[(3R)-1,1-dioxothiolan-3-yl]propanamide
    —— (2S)-2-(3,4-dimethylphenyl)sulfanyl-N-(2-phenylethyl)propanamide —— C19H23NOS
    (2S)-2-(3,4-dimethylphenyl)sulfanyl-N-(2-phenylethyl)propanamide
    —— (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-tert-butylpropanamide —— C15H18BrN3O2S
    (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-tert-butylpropanamide
    —— (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-cyanoethyl)-N-methylpropanamide —— C15H15BrN4O2S
    (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-cyanoethyl)-N-methylpropanamide
    —— (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N,N-di(propan-2-yl)propanamide —— C17H22BrN3O2S
    (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N,N-di(propan-2-yl)propanamide
    —— (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-propylpropanamide —— C14H16BrN3O2S
    (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-propylpropanamide
    —— (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-propylpropanamide —— C14H16BrN3O2S
    (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-propylpropanamide
    —— (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)propanamide —— C15H18BrN3O2S
    (2R)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-(2-methylpropyl)propanamide
    —— (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-tert-butylpropanamide —— C15H18BrN3O2S
    (2S)-2-[[5-(2-bromophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-N-tert-butylpropanamide
    —— [(2R)-1-oxo-1-(prop-2-enylamino)propan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C14H16BrNO3S
    [(2R)-1-oxo-1-(prop-2-enylamino)propan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2R)-1-(2-methoxyethylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C14H18BrNO4S
    [(2R)-1-(2-methoxyethylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2S)-1-(2-methylpropylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C15H20BrNO3S
    [(2S)-1-(2-methylpropylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2S)-1-(methoxycarbonylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C13H14BrNO5S
    [(2S)-1-(methoxycarbonylamino)-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [(2R)-1-[2-cyanoethyl(methyl)amino]-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate —— C15H17BrN2O3S
    [(2R)-1-[2-cyanoethyl(methyl)amino]-1-oxopropan-2-yl] 2-(4-bromophenyl)sulfanylacetate
    —— [2-oxo-2-(2-phenylsulfanylanilino)ethyl] 2-[(3S)-1,1-dioxothiolan-3-yl]acetate —— C20H21NO5S2
    [2-oxo-2-(2-phenylsulfanylanilino)ethyl] 2-[(3S)-1,1-dioxothiolan-3-yl]acetate
    —— [2-oxo-2-(2-phenylsulfanylanilino)ethyl] 2-[(3R)-1,1-dioxothiolan-3-yl]acetate —— C20H21NO5S2
    [2-oxo-2-(2-phenylsulfanylanilino)ethyl] 2-[(3R)-1,1-dioxothiolan-3-yl]acetate
    —— (3S)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-3-ylpropan-1-amine —— C17H22N2S
    (3S)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-3-ylpropan-1-amine
    —— (2R)-N-(2-methylpropyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C14H23N3OS
    (2R)-N-(2-methylpropyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide
    —— (2S)-N-[(2-chlorophenyl)methyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C17H20ClN3OS
    (2S)-N-[(2-chlorophenyl)methyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide
    —— (3S)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-2-ylpropan-1-amine —— C17H22N2S
    (3S)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-2-ylpropan-1-amine
    —— (2S)-N-[(4-methylphenyl)methyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C18H23N3OS
    (2S)-N-[(4-methylphenyl)methyl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide
    —— (2R)-N-(propan-2-ylcarbamoyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C14H22N4O2S
    (2R)-N-(propan-2-ylcarbamoyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide
    —— (3R)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-2-ylpropan-1-amine —— C17H22N2S
    (3R)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-2-ylpropan-1-amine
    —— (2R)-N-(thiophen-2-ylmethyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C15H19N3OS2
    (2R)-N-(thiophen-2-ylmethyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide
    —— (2S)-N-(2-methylpropyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C14H23N3OS
    (2S)-N-(2-methylpropyl)-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide
    —— (3S)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-4-ylpropan-1-amine —— C17H22N2S
    (3S)-3-(4-propan-2-ylsulfanylphenyl)-3-pyridin-4-ylpropan-1-amine
    —— (2R)-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide —— C14H21N3O3S2
    (2R)-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(4,5,6-trimethylpyrimidin-2-yl)sulfanylpropanamide