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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— [5-(3,5-Dichlorophenylthio)-1-dodecyl-4-isopropyl-1H-imidazol-2-yl]methanol 178979-07-2 C25H38Cl2N2OS
    [5-(3,5-Dichlorophenylthio)-1-dodecyl-4-isopropyl-1H-imidazol-2-yl]methanol
    —— 1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-((2-methyl-3-pyridinyl)methyl)- 178980-51-3 C20H21Cl2N3OS
    1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-((2-methyl-3-pyridinyl)methyl)-
    —— [5-(3,5-Dichlorophenylthio)-1-(4-aminobenzyl)-4-isopropyl-1H-imidazol-2-yl]methanol 178980-71-7 C20H21Cl2N3OS
    [5-(3,5-Dichlorophenylthio)-1-(4-aminobenzyl)-4-isopropyl-1H-imidazol-2-yl]methanol
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole 178979-88-9 C19H20Cl2N4S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole 178979-84-5 C20H20Cl2N4O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole
    —— 1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, carbamate (ester) 178980-45-5 C22H24Cl2N4O2S
    1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, carbamate (ester)
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole 178979-87-8 C19H20Cl2N4S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-2-methylamidinomethyl-1H-imidazole 178979-75-4 C16H20Cl2N4S
    5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-2-methylamidinomethyl-1H-imidazole
    —— 1-Benzyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-ylmethanol 178979-05-0 C20H20Cl2N2OS
    1-Benzyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-ylmethanol
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazole 178980-21-7 C24H22Cl2N4O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazole
    —— [2-(2-amino-6-chloropyrimidin-4-ylsulfanyl)ethyl]carbamic acid tert-butyl ester 1052648-77-7 C11H17ClN4O2S
    [2-(2-amino-6-chloropyrimidin-4-ylsulfanyl)ethyl]carbamic acid tert-butyl ester
    —— 6-sec-Butoxy-2-(3-chloro-phenylsulfanyl)-3H-pyrimidin-4-one 284681-69-2 C14H15ClN2O2S
    6-sec-Butoxy-2-(3-chloro-phenylsulfanyl)-3H-pyrimidin-4-one
    —— 2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(3-(2-pyridyl)propyl)-1H-imidazole 178980-23-9 C22H24Cl2N4O2S
    2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(3-(2-pyridyl)propyl)-1H-imidazole
    —— 2-Aminomethyl-5-(3-chlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole 178979-64-1 C15H20ClN3S
    2-Aminomethyl-5-(3-chlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole
    —— 1-Chlor-4,4-dimethyl-3-phenylthio-2-pentanon 53258-87-0 C13H17ClOS
    1-Chlor-4,4-dimethyl-3-phenylthio-2-pentanon
    —— 1-(p-N-acetylaminobenzyl)-5-(3,5-dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-1H-imidazole 178980-10-4 C22H23Cl2N3O2S
    1-(p-N-acetylaminobenzyl)-5-(3,5-dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-1H-imidazole
    —— {5-[(3,5-Dichlorophenyl)sulfanyl]-4-(1-methylethyl)-1-(thiophen-2-ylmethyl)-1h-imidazol-2-yl}methanol 178980-19-3 C18H18Cl2N2OS2
    {5-[(3,5-Dichlorophenyl)sulfanyl]-4-(1-methylethyl)-1-(thiophen-2-ylmethyl)-1h-imidazol-2-yl}methanol
    —— 3-Acetoxy-4,4-dimethyl-1-phenylthio-2-pentanon 65302-93-4 C15H20O3S
    3-Acetoxy-4,4-dimethyl-1-phenylthio-2-pentanon
    —— 1H-Imidazole-2-ethanol, 1-((4-aminophenyl)methyl)-5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)- 178980-33-1 C21H23Cl2N3OS
    1H-Imidazole-2-ethanol, 1-((4-aminophenyl)methyl)-5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-3-ylmethyl)-1H-imidazole 178979-86-7 C19H20Cl2N4S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-3-ylmethyl)-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazol-2-ylmethanol 178980-74-0 C23H21Cl2N3OS
    5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazol-2-ylmethanol
    —— 5-(3,5-Dichlorophenylthio)-2-(-2-carbamoyloxyethyl)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole 178980-32-0 C21H22Cl2N4O2S
    5-(3,5-Dichlorophenylthio)-2-(-2-carbamoyloxyethyl)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole
    —— 6-(sec-butoxy)-2-((4-chlorophenyl)thio)pyrimidin-4-amine 284681-50-1 C14H16ClN3OS
    6-(sec-butoxy)-2-((4-chlorophenyl)thio)pyrimidin-4-amine
    —— 2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1-n-propyl-1H-imidazole 178979-44-7 C17H22ClN3O2S
    2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1-n-propyl-1H-imidazole
    —— 6-sec-Butoxy-2-m-tolylsulfanyl-pyrimidin-4-ylamine 284681-46-5 C15H19N3OS
    6-sec-Butoxy-2-m-tolylsulfanyl-pyrimidin-4-ylamine
    —— 2-Aminomethyl-1-ethyl-4-isopropyl-5-phenylthio-1H-imidazole 178979-66-3 C15H21N3S
    2-Aminomethyl-1-ethyl-4-isopropyl-5-phenylthio-1H-imidazole
    —— 1-benzyl-4-benzylsulfanyl-2,6-dimethyl-pyridinium; iodide 6322-87-8 C21H22NS*I
    1-benzyl-4-benzylsulfanyl-2,6-dimethyl-pyridinium; iodide
    —— 4-(5-Bromo-6-chloro-pyridine-3-sulfonyl)-5-methylsulfanyl-thiophene-2-carboxamidine 631904-38-6 C11H9BrClN3O2S3
    4-(5-Bromo-6-chloro-pyridine-3-sulfonyl)-5-methylsulfanyl-thiophene-2-carboxamidine
    —— 3-acetoxy-1-phenyl-1-phenylthio-2-propanone 53258-90-5 C17H16O3S
    3-acetoxy-1-phenyl-1-phenylthio-2-propanone
    —— 4(1H)-Pyrimidinone, 2-((3,5-dimethylphenyl)thio)-6-(1-methylpropoxy)- 284681-66-9 C16H20N2O2S
    4(1H)-Pyrimidinone, 2-((3,5-dimethylphenyl)thio)-6-(1-methylpropoxy)-
    —— 6-sec-Butoxy-2-chloro-4-aminopyrimidine 284681-72-7 C15H18N2O2S
    6-sec-Butoxy-2-chloro-4-aminopyrimidine
    —— 1-({[2,3-bis(phenylsulfanyl)prop-2-enyl]oxy}methyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil 1187743-18-5 C31H32N2O3S2
    1-({[2,3-bis(phenylsulfanyl)prop-2-enyl]oxy}methyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil
    —— 6-(3,5-dimethylbenzyl)-5-ethyl-1-[({3-[(2-methylsulfanyl)phenyl]prop-2-ynyl}oxy)methyl]uracil 1187742-95-5 C26H28N2O3S
    6-(3,5-dimethylbenzyl)-5-ethyl-1-[({3-[(2-methylsulfanyl)phenyl]prop-2-ynyl}oxy)methyl]uracil
    —— 6-sec-Butoxy-2-o-tolylsulfanyl-pyrimidin-4-ylamine 284681-45-4 C15H19N3OS
    6-sec-Butoxy-2-o-tolylsulfanyl-pyrimidin-4-ylamine
    —— 6-sec-Butoxy-2-p-tolylsulfanyl-3H-pyrimidin-4-one 284681-73-8 C15H18N2O2S
    6-sec-Butoxy-2-p-tolylsulfanyl-3H-pyrimidin-4-one
    —— 6-sec-Butoxy-2-(2-chloro-phenylsulfanyl)-3H-pyrimidin-4-one 284681-68-1 C14H15ClN2O2S
    6-sec-Butoxy-2-(2-chloro-phenylsulfanyl)-3H-pyrimidin-4-one
    —— 2-sec-Butoxy-6-m-tolylsulfanyl-pyrimidin-4-ylamine 284681-85-2 C15H19N3OS
    2-sec-Butoxy-6-m-tolylsulfanyl-pyrimidin-4-ylamine
    —— 4(1H)-Pyrimidinone, 2-((4-methoxyphenyl)thio)-6-(1-methylpropoxy)- 284681-76-1 C15H18N2O3S
    4(1H)-Pyrimidinone, 2-((4-methoxyphenyl)thio)-6-(1-methylpropoxy)-
    —— 4-[(3,4-Difluorophenyl)methylthio]pyridine-2-carbonitrile 225112-75-4 C13H8F2N2S
    4-[(3,4-Difluorophenyl)methylthio]pyridine-2-carbonitrile
    —— 4(3H)-Pyrimidinone, 3-methyl-6-(1-methylpropoxy)-2-(phenylthio)- 284681-82-9 C15H18N2O2S
    4(3H)-Pyrimidinone, 3-methyl-6-(1-methylpropoxy)-2-(phenylthio)-
    —— 2-Cyanomethylsulfanyl-isonicotinonitrile 256657-48-4 C8H5N3S
    2-Cyanomethylsulfanyl-isonicotinonitrile
    —— 4-Cyanomethylsulfanyl-pyridine-2-carbonitrile 256657-56-4 C8H5N3S
    4-Cyanomethylsulfanyl-pyridine-2-carbonitrile
    —— 2-[(2,5-dimethoxyphenyl)thio]pyrimidine 646511-19-5 C12H12N2O2S
    2-[(2,5-dimethoxyphenyl)thio]pyrimidine
    —— 4(1H)-Pyrimidinone, 2-((4-fluorophenyl)thio)-6-(1-methylpropoxy)- 284681-67-0 C14H15FN2O2S
    4(1H)-Pyrimidinone, 2-((4-fluorophenyl)thio)-6-(1-methylpropoxy)-
    —— 4-Pyrimidinamine, 6-(butylthio)-2-chloro- 284681-94-3 C8H12ClN3S
    4-Pyrimidinamine, 6-(butylthio)-2-chloro-
    —— 3-methylsulfanyl-1-[1-(3-methylsulfanyl-1,2,4-triazol-1-yl)cyclohexyl]-1,2,4-triazole 118730-24-8 C12H18N6S2
    3-methylsulfanyl-1-[1-(3-methylsulfanyl-1,2,4-triazol-1-yl)cyclohexyl]-1,2,4-triazole
    —— 2-Butylmercapto-4-amino-6-chlor-pyrimidin 90153-59-6 C8H12ClN3S
    2-Butylmercapto-4-amino-6-chlor-pyrimidin
    —— 2-sec-Butoxy-6-phenylsulfanyl-3H-pyrimidin-4-one 284681-89-6 C14H16N2O2S
    2-sec-Butoxy-6-phenylsulfanyl-3H-pyrimidin-4-one
    —— 4(1H)-Pyrimidinone, 2-((3-methoxyphenyl)thio)-6-(1-methylpropoxy)- 284681-75-0 C15H18N2O3S
    4(1H)-Pyrimidinone, 2-((3-methoxyphenyl)thio)-6-(1-methylpropoxy)-
    —— 4(1H)-Pyrimidinone, 2-(butylthio)-6-(phenylthio)- 284682-03-7 C14H16N2OS2
    4(1H)-Pyrimidinone, 2-(butylthio)-6-(phenylthio)-