摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 4-chloro-7-methoxy-10<i>H</i>-pyrido[2,3-<i>b</i>]pyrimido[4,5-<i>e</i>][1,4]thiazin-2-ylamine 63931-20-4 C10H8ClN5OS
    4-chloro-7-methoxy-10<i>H</i>-pyrido[2,3-<i>b</i>]pyrimido[4,5-<i>e</i>][1,4]thiazin-2-ylamine
    —— 3-(methylthio)-5-(pyridin-4-yl)isoxazole 120803-22-7 C9H8N2OS
    3-(methylthio)-5-(pyridin-4-yl)isoxazole
    —— 4-[(4-chlorophenyl)thio]-N-hydroxybutanamide 59513-54-1 C10H12ClNO2S
    4-[(4-chlorophenyl)thio]-N-hydroxybutanamide
    —— 2-[2-fluoro-4-(methylthio)phenyl]-5-[(1-{1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}ethyl)oxy]pyrazine 1032825-61-8 C23H28FN5O2S
    2-[2-fluoro-4-(methylthio)phenyl]-5-[(1-{1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}ethyl)oxy]pyrazine
    —— α-Methylsulfonylmethyl-acrylsaeure 36525-60-7 C5H8O4S
    α-Methylsulfonylmethyl-acrylsaeure
    —— isobutyl chloromethyl sulfoxide 77407-41-1 C5H11ClOS
    isobutyl chloromethyl sulfoxide
    —— N-[2-[(2,4-difluorophenyl)thio]-4-oxoquinazolin-3(4H)-yl]methanesulfonamide 1018471-52-7 C15H11F2N3O3S2
    N-[2-[(2,4-difluorophenyl)thio]-4-oxoquinazolin-3(4H)-yl]methanesulfonamide
    —— (2E)-Methyl 3-<Dimethyl(phenyl)silyl>-2-<(E)-1'-<2''-(1,3-dioxan-2-ylmethyl)-1'',3''-dithian-2''-yl>-3'-methyl-4'-oxopent-2'-enyloxymethyl>propenoate 145746-28-7 C28H40O6S2Si
    (2E)-Methyl 3-<Dimethyl(phenyl)silyl>-2-<(E)-1'-<2''-(1,3-dioxan-2-ylmethyl)-1'',3''-dithian-2''-yl>-3'-methyl-4'-oxopent-2'-enyloxymethyl>propenoate
    —— 1-Methyl-4-thia-3,9,10a-triaza-benzo[f]azulen-10-ol 81382-63-0 C11H9N3OS
    1-Methyl-4-thia-3,9,10a-triaza-benzo[f]azulen-10-ol
    —— 2-methyl-5-(4-methyl-1-piperazinyl)imidazo<2,1-b><1,3,5>benzothiadiazepine 81382-79-8 C16H19N5S
    2-methyl-5-(4-methyl-1-piperazinyl)imidazo<2,1-b><1,3,5>benzothiadiazepine
    —— triethylammonium (4-chlorophenylthio)difluoromethanesulfonate 744221-74-7 C6H15N*C7H5ClF2O3S2
    triethylammonium (4-chlorophenylthio)difluoromethanesulfonate
    —— 2-methylimidazo<2,1-b><1,3,5>benzothiadiazepine-5(6H)-one 87011-02-7 C11H9N3OS
    2-methylimidazo<2,1-b><1,3,5>benzothiadiazepine-5(6H)-one
    —— 1-<2-(4-methyl-2-imidazolyl)thiophenyliminocarbonyl>-4-methylpiperazine 81382-64-1 C16H21N5OS
    1-<2-(4-methyl-2-imidazolyl)thiophenyliminocarbonyl>-4-methylpiperazine
    —— 3-(3-Isoxazolyl)-2-thiophenesulfonylisocyanate 103092-74-6 C8H4N2O4S2
    3-(3-Isoxazolyl)-2-thiophenesulfonylisocyanate
    —— 4-methyl-2-(2-aminophenylthio)imidazole 88251-73-4 C10H11N3S
    4-methyl-2-(2-aminophenylthio)imidazole
    —— 3-(4-chlorobenzyl)-2-methylthio-5-(morpholino)pyrimidine-4(3H)-one 1359818-39-5 C16H18ClN3O2S
    3-(4-chlorobenzyl)-2-methylthio-5-(morpholino)pyrimidine-4(3H)-one
    —— 5-(t-butoxycarbonyl)amino-3-(4-chlorobenzyl)-2-(methylthio)pyrimidine-4(3H)-one 1359818-40-8 C17H20ClN3O3S
    5-(t-butoxycarbonyl)amino-3-(4-chlorobenzyl)-2-(methylthio)pyrimidine-4(3H)-one
    —— 5-amino-3-(4-chlorobenzyl)-2-(methylthio)pyrimidine-4(3H)-one 1359818-41-9 C12H12ClN3OS
    5-amino-3-(4-chlorobenzyl)-2-(methylthio)pyrimidine-4(3H)-one
    —— Oct-6-yne-1-thiol 77213-95-7 C8H14S
    Oct-6-yne-1-thiol
    —— 6-(4-chloro-phenylsulfanyl)-hexylamine 149599-92-8 C12H18ClNS
    6-(4-chloro-phenylsulfanyl)-hexylamine
    —— 1,1,2-trifluoro-2-(p-chlorophenylthio)propane 817562-59-7 C9H8ClF3S
    1,1,2-trifluoro-2-(p-chlorophenylthio)propane
    —— 1.6-Bis-(2.6-dichlor-benzylmercapto)-dipyridazo<4,5-b;4,5-e>-1.4-dithiin 13616-23-4 C22H12Cl4N4S4
    1.6-Bis-(2.6-dichlor-benzylmercapto)-dipyridazo<4,5-b;4,5-e>-1.4-dithiin
    —— 3-chloro-2-(2,4-dichlorophenylthio)-N-methyl-sulphonyl-aniline 210823-47-5 C13H10Cl3NO2S2
    3-chloro-2-(2,4-dichlorophenylthio)-N-methyl-sulphonyl-aniline
    —— 1,4-Bis<(2-chloroethyl)thio>-2,3,5,6-tetrafluorobenzene 16956-51-7 C10H8Cl2F4S2
    1,4-Bis<(2-chloroethyl)thio>-2,3,5,6-tetrafluorobenzene
    —— 3-oxo-4-propyl-3,4-dihydropyrazin-2-yl imidothiocarbamate hydrobromide 1187017-28-2 BrH*C8H12N4OS
    3-oxo-4-propyl-3,4-dihydropyrazin-2-yl imidothiocarbamate hydrobromide
    —— 5-Bromo-4-chlor-6-(2-methylpyrrolidin-1-yl)-2-methylthiopyrimidine 946531-37-9 C10H13BrClN3S
    5-Bromo-4-chlor-6-(2-methylpyrrolidin-1-yl)-2-methylthiopyrimidine
    —— 2-(2'-methylthiothiazol-4'-yl)pyrazine 91516-41-5 C8H7N3S2
    2-(2'-methylthiothiazol-4'-yl)pyrazine
    —— Allyl-p-dimethylaminophenyl-sulfid 62291-61-6 C11H15NS
    Allyl-p-dimethylaminophenyl-sulfid
    —— 3-chloro-2-(2,4-dichlorophenylthio)-aniline 210823-45-3 C12H8Cl3NS
    3-chloro-2-(2,4-dichlorophenylthio)-aniline
    —— 5-Chlor-2-(4-methoxyphenylthio)-phenylessigsaeure 63186-41-4 C15H13ClO3S
    5-Chlor-2-(4-methoxyphenylthio)-phenylessigsaeure
    —— 4-(ethylthio)-N,N-dimethylaniline 62291-59-2 C10H15NS
    4-(ethylthio)-N,N-dimethylaniline
    —— p-Dimethylaminophenyl-isopropyl-sulfid 62291-60-5 C11H17NS
    p-Dimethylaminophenyl-isopropyl-sulfid
    —— 5-Chlor-2-(4-methoxyphenylthio)-phenylacetonitril 63186-39-0 C15H12ClNOS
    5-Chlor-2-(4-methoxyphenylthio)-phenylacetonitril
    —— 5-Chlor-2-(4-methoxyphenylthio)-benzylchlorid 63186-37-8 C14H12Cl2OS
    5-Chlor-2-(4-methoxyphenylthio)-benzylchlorid
    —— 7-methylsulfanyl-heptan-1-ol 101397-91-5 C8H18OS
    7-methylsulfanyl-heptan-1-ol
    —— 5-(4'-N,N-dimethylaminophenylthio)tetrazole 92658-05-4 C9H11N5S
    5-(4'-N,N-dimethylaminophenylthio)tetrazole
    —— methyl 3-(p-tolylthio)pyrrolo[2, 1-a]isoquinoline-1-carboxylate 1331782-13-8 C21H17NO2S
    methyl 3-(p-tolylthio)pyrrolo[2, 1-a]isoquinoline-1-carboxylate
    —— 2-Ethoxymethylenamino-3,4-dicyan-5-ethylmercapto-pyrrol 1500-89-6 C11H12N4OS
    2-Ethoxymethylenamino-3,4-dicyan-5-ethylmercapto-pyrrol
    —— 2-(4-Chloro-phenylsulfanyl)-N-thiazol-2-yl-nicotinamide 97936-25-9 C15H10ClN3OS2
    2-(4-Chloro-phenylsulfanyl)-N-thiazol-2-yl-nicotinamide
    —— (4-(4,4-difluoro-1-piperidinyl)-6-{[(5-methyl-1H-1,2,4-triazol-3-yl)thio]methyl}-2-pyridinyl)(2,2,2-trifluoroethyl)carbamic acid tert-butyl ester 1186689-82-6 C21H27F5N6O2S
    (4-(4,4-difluoro-1-piperidinyl)-6-{[(5-methyl-1H-1,2,4-triazol-3-yl)thio]methyl}-2-pyridinyl)(2,2,2-trifluoroethyl)carbamic acid tert-butyl ester
    —— tert-Butyl-dimethyl-[2-(2-pentyl-[1,3]dithian-2-yl)-ethoxy]-silane 769936-14-3 C17H36OS2Si
    tert-Butyl-dimethyl-[2-(2-pentyl-[1,3]dithian-2-yl)-ethoxy]-silane
    —— benzyl 2-(2-(4-methoxyphenylthio)phenyl)acetate 1191112-15-8 C22H20O3S
    benzyl 2-(2-(4-methoxyphenylthio)phenyl)acetate
    —— 2,3-Dihydro-2-methylthiazolo<3,2-a>pyrimidon-(5) 41200-23-1 C7H8N2OS
    2,3-Dihydro-2-methylthiazolo<3,2-a>pyrimidon-(5)
    —— N-[5-(p-tolylsulfanyl)-1,3,4-thiadiazol-2-yl]benzamide 1095155-00-2 C16H13N3OS2
    N-[5-(p-tolylsulfanyl)-1,3,4-thiadiazol-2-yl]benzamide
    —— 2-(1H-indol-3-ylsulfanyl)-N,N-dimethyl benzamide 857499-89-9 C17H16N2OS
    2-(1H-indol-3-ylsulfanyl)-N,N-dimethyl benzamide
    —— [2-(1H-indol-3-ylsulfanyl)-benzyl]dimethylamine 857498-26-1 C17H18N2S
    [2-(1H-indol-3-ylsulfanyl)-benzyl]dimethylamine
    —— 6-(Phenylsulfanyl)-9-thiabicyclo[3.3.1]non-2-ene 23871-56-9 C14H16S2
    6-(Phenylsulfanyl)-9-thiabicyclo[3.3.1]non-2-ene
    —— 2-(4-Fluoro-3-methyl-phenylsulfanyl)-hexanoic acid hydroxyamide 1043450-32-3 C13H18FNO2S
    2-(4-Fluoro-3-methyl-phenylsulfanyl)-hexanoic acid hydroxyamide
    —— 4-bromo-5-phenylthiofuran-2(5H)-one 171568-18-6 C10H7BrO2S
    4-bromo-5-phenylthiofuran-2(5H)-one
    —— 2-(4-fluoro-3-methyl-phenylsulfanyl)-hexanoic acid methyl ester 1043450-31-2 C14H19FO2S
    2-(4-fluoro-3-methyl-phenylsulfanyl)-hexanoic acid methyl ester