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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 3-[(3-bromophenyl)methylsulfanyl]-N-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazol-5-amine —— C14H12BrN5OS
    3-[(3-bromophenyl)methylsulfanyl]-N-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazol-5-amine
    —— 2-[[5-[(2E)-2-benzylidenehydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C11H12N6OS
    2-[[5-[(2E)-2-benzylidenehydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 1-(2,6-dimethylphenyl)-3-[(E)-(4-methylsulfanylphenyl)methylideneamino]thiourea —— C17H19N3S2
    1-(2,6-dimethylphenyl)-3-[(E)-(4-methylsulfanylphenyl)methylideneamino]thiourea
    —— N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-prop-2-enylsulfanyl-1H-1,2,4-triazol-5-amine —— C16H22N6S
    N-[(E)-[4-(diethylamino)phenyl]methylideneamino]-3-prop-2-enylsulfanyl-1H-1,2,4-triazol-5-amine
    —— N-[(E)-benzylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine —— C13H17N5S
    N-[(E)-benzylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine
    —— 2-[[5-[(2E)-2-[[4-(diethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetonitrile —— C15H19N7S
    2-[[5-[(2E)-2-[[4-(diethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetonitrile
    —— 2-[[5-[(2E)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]-N-tert-butylacetamide —— C15H19BrN6OS
    2-[[5-[(2E)-2-[(3-bromophenyl)methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]-N-tert-butylacetamide
    —— N-[(E)-furan-2-ylmethylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine —— C11H15N5OS
    N-[(E)-furan-2-ylmethylideneamino]-3-(2-methylpropylsulfanyl)-1H-1,2,4-triazol-5-amine
    —— N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-propan-2-ylsulfanyl-1H-1,2,4-triazol-5-amine —— C14H20N6S
    N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-propan-2-ylsulfanyl-1H-1,2,4-triazol-5-amine
    —— N-tert-butyl-2-[[5-[(2E)-2-[[4-(dimethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C17H25N7OS
    N-tert-butyl-2-[[5-[(2E)-2-[[4-(dimethylamino)phenyl]methylidene]hydrazinyl]-1H-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— 4-methyl-2-[(2E)-2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]-1H-pyrimidin-6-one —— C13H14N4OS
    4-methyl-2-[(2E)-2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]-1H-pyrimidin-6-one
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-methylphenyl)methanimine —— C17H16N4S
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-methylphenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-2-ylmethanimine —— C16H15N5S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-2-ylmethanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-3-ylmethanimine —— C16H15N5S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-pyridin-3-ylmethanimine
    —— 3-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]phenol —— C17H16N4OS
    3-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]phenol
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2,3,6-trichlorophenyl)methanimine —— C16H11Cl3N4S
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2,3,6-trichlorophenyl)methanimine
    —— 4-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]-N,N-dimethylaniline —— C19H21N5S
    4-[(E)-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)iminomethyl]-N,N-dimethylaniline
    —— 3-[(E)-(3-benzylsulfanyl-1,2,4-triazol-4-yl)iminomethyl]phenol —— C16H14N4OS
    3-[(E)-(3-benzylsulfanyl-1,2,4-triazol-4-yl)iminomethyl]phenol
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-bromophenyl)methanimine —— C17H15BrN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-bromophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-chlorophenyl)methanimine —— C17H15ClN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-chlorophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-thiophen-2-ylmethanimine —— C14H12N4S2
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-thiophen-2-ylmethanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-fluorophenyl)methanimine —— C17H15FN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(4-fluorophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-fluorophenyl)methanimine —— C17H15FN4S
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(2-fluorophenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(3-methylthiophen-2-yl)methanimine —— C16H16N4S2
    (E)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-1-(3-methylthiophen-2-yl)methanimine
    —— (E,Z)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-2-methyl-3-phenylprop-2-en-1-imine —— C20H20N4S
    (E,Z)-N-(3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-yl)-2-methyl-3-phenylprop-2-en-1-imine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine —— C17H16N4S2
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(4-methylsulfanylphenyl)methanimine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-methylthiophen-2-yl)methanimine —— C15H14N4S2
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(3-methylthiophen-2-yl)methanimine
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(5-methylfuran-2-yl)methanimine —— C15H14N4OS
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(5-methylfuran-2-yl)methanimine
    —— 4-[(E)-(4-methylsulfanylphenyl)methylideneamino]-3-propan-2-yl-1H-1,2,4-triazole-5-thione —— C13H16N4S2
    4-[(E)-(4-methylsulfanylphenyl)methylideneamino]-3-propan-2-yl-1H-1,2,4-triazole-5-thione
    —— (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2-methylphenyl)methanimine —— C17H16N4S
    (E)-N-(3-benzylsulfanyl-1,2,4-triazol-4-yl)-1-(2-methylphenyl)methanimine
    —— 3-Methyl-4-{(E)-[4-(methylsulfanyl)benzylidene]amino}-1H-1,2,4-triazole-5(4H)-thione —— C11H12N4S2
    3-Methyl-4-{(E)-[4-(methylsulfanyl)benzylidene]amino}-1H-1,2,4-triazole-5(4H)-thione
    —— (E)-N-(3-benzylsulfanyl-5-propyl-1,2,4-triazol-4-yl)-1-(2-methylphenyl)methanimine —— C20H22N4S
    (E)-N-(3-benzylsulfanyl-5-propyl-1,2,4-triazol-4-yl)-1-(2-methylphenyl)methanimine
    —— (E)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-ethyl-1,2,4-triazol-4-yl]-1-phenylmethanimine —— C18H17BrN4S
    (E)-N-[3-[(4-bromophenyl)methylsulfanyl]-5-ethyl-1,2,4-triazol-4-yl]-1-phenylmethanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-methylphenyl)methanimine —— C17H15ClN4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-methylphenyl)methanimine
    —— (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine —— C18H17ClN4S
    (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(4-ethylphenyl)methanimine
    —— (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine —— C15H13ClN4S2
    (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(3-methylthiophen-2-yl)methanimine
    —— 4-[(E)-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]iminomethyl]-N,N-dimethylaniline —— C18H18ClN5S
    4-[(E)-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]iminomethyl]-N,N-dimethylaniline
    —— (E)-1-(2-chlorophenyl)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]methanimine —— C16H12Cl2N4S
    (E)-1-(2-chlorophenyl)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]methanimine
    —— (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine —— C16H12ClFN4S
    (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine
    —— (E)-1-(4-chlorophenyl)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]methanimine —— C16H12Cl2N4S
    (E)-1-(4-chlorophenyl)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]methanimine
    —— (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine —— C16H12ClFN4S
    (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(4-fluorophenyl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-pyridin-3-ylmethanimine —— C15H12ClN5S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-pyridin-3-ylmethanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine —— C16H12ClFN4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(2-fluorophenyl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine —— C17H15ClN4S2
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(4-methylsulfanylphenyl)methanimine
    —— 3-[(E)-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]iminomethyl]phenol —— C16H13ClN4OS
    3-[(E)-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]iminomethyl]phenol
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(5-methylfuran-2-yl)methanimine —— C15H13ClN4OS
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-(5-methylfuran-2-yl)methanimine
    —— (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-phenylmethanimine —— C16H13ClN4S
    (E)-N-[3-[(4-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-phenylmethanimine
    —— (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-phenylmethanimine —— C16H13ClN4S
    (E)-N-[3-[(2-chlorophenyl)methylsulfanyl]-1,2,4-triazol-4-yl]-1-phenylmethanimine
    —— 2-(4-bromo-2,5-dimethylphenyl)sulfanyl-N-[(E)-[(2S)-2-methylcyclohexylidene]amino]acetamide —— C17H23BrN2OS
    2-(4-bromo-2,5-dimethylphenyl)sulfanyl-N-[(E)-[(2S)-2-methylcyclohexylidene]amino]acetamide
    —— 2-(4-methoxyphenoxy)-N'-{(E)-[5-(phenylsulfanyl)furan-2-yl]methylidene}acetohydrazide —— C20H18N2O4S
    2-(4-methoxyphenoxy)-N'-{(E)-[5-(phenylsulfanyl)furan-2-yl]methylidene}acetohydrazide