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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[2-(4-fluoro-2-methylphenyl)ethyl]-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)sulfanyl]acetamide —— C13H14FN3OS3
    N-[2-(4-fluoro-2-methylphenyl)ethyl]-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)sulfanyl]acetamide
    —— (2R,3S)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pentan-2-amine —— C9H18N4S
    (2R,3S)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pentan-2-amine
    —— (2R)-3-methyl-1-pyridin-2-ylsulfanylbutan-2-amine —— C10H16N2S
    (2R)-3-methyl-1-pyridin-2-ylsulfanylbutan-2-amine
    —— (2S,3R)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylpentan-2-amine —— C10H19N3S
    (2S,3R)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylpentan-2-amine
    —— (2R)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine —— C8H16N4S
    (2R)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine
    —— (2S)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine —— C8H16N4S
    (2S)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]butan-2-amine
    —— (2R,3R)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylpentan-2-amine —— C10H19N3S
    (2R,3R)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylpentan-2-amine
    —— (2R,3R)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pentan-2-amine —— C9H18N4S
    (2R,3R)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pentan-2-amine
    —— (2R,3R)-3-methyl-1-pyridin-2-ylsulfanylpentan-2-amine —— C11H18N2S
    (2R,3R)-3-methyl-1-pyridin-2-ylsulfanylpentan-2-amine
    —— (2R)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine —— C9H17N3S
    (2R)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine
    —— (2S,3S)-3-methyl-1-pyridin-2-ylsulfanylpentan-2-amine —— C11H18N2S
    (2S,3S)-3-methyl-1-pyridin-2-ylsulfanylpentan-2-amine
    —— (2S,3S)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylpentan-2-amine —— C10H19N3S
    (2S,3S)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylpentan-2-amine
    —— (2S)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine —— C9H17N3S
    (2S)-3-methyl-1-(1-methylimidazol-2-yl)sulfanylbutan-2-amine
    —— (2S,3R)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pentan-2-amine —— C9H18N4S
    (2S,3R)-3-methyl-1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]pentan-2-amine
    —— (2S)-3-methyl-1-pyrimidin-2-ylsulfanylbutan-2-amine —— C9H15N3S
    (2S)-3-methyl-1-pyrimidin-2-ylsulfanylbutan-2-amine
    —— (2R)-3-methyl-1-pyrimidin-2-ylsulfanylbutan-2-amine —— C9H15N3S
    (2R)-3-methyl-1-pyrimidin-2-ylsulfanylbutan-2-amine
    —— (2S)-3-methyl-1-pyridin-2-ylsulfanylbutan-2-amine —— C10H16N2S
    (2S)-3-methyl-1-pyridin-2-ylsulfanylbutan-2-amine
    —— [(2S)-1-(6-chloro-2-methylsulfanylpyrimidin-4-yl)pyrrolidin-2-yl]methanol —— C10H14ClN3OS
    [(2S)-1-(6-chloro-2-methylsulfanylpyrimidin-4-yl)pyrrolidin-2-yl]methanol
    —— [(2S,3S)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate —— C7H11NO3S
    [(2S,3S)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate
    —— (3R)-3-methylhexanethial —— C7H14S
    (3R)-3-methylhexanethial
    —— [(2R,3S)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate —— C7H11NO3S
    [(2R,3S)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate
    —— (3S)-3-methylhexanethial —— C7H14S
    (3S)-3-methylhexanethial
    —— [(2R,3R)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate —— C7H11NO3S
    [(2R,3R)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate
    —— (2S)-2-(4-methylphenyl)sulfanyl-N-[2-(2-methyl-1,2,4-triazol-3-yl)ethyl]propanamide —— C15H20N4OS
    (2S)-2-(4-methylphenyl)sulfanyl-N-[2-(2-methyl-1,2,4-triazol-3-yl)ethyl]propanamide
    —— (2R)-2-(4-methylphenyl)sulfanyl-N-[2-(2-methyl-1,2,4-triazol-3-yl)ethyl]propanamide —— C15H20N4OS
    (2R)-2-(4-methylphenyl)sulfanyl-N-[2-(2-methyl-1,2,4-triazol-3-yl)ethyl]propanamide
    —— [(2S,3R)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate —— C7H11NO3S
    [(2S,3R)-3-amino-2,4-dimethyl-3H-thiophen-2-yl] hydrogen carbonate
    —— N-[(2S)-2-hydroxy-2,3-dimethylbutyl]-3-pyridin-2-ylsulfanylpropanamide —— C14H22N2O2S
    N-[(2S)-2-hydroxy-2,3-dimethylbutyl]-3-pyridin-2-ylsulfanylpropanamide
    —— N-[(2R)-2-hydroxy-2,3-dimethylbutyl]-3-pyridin-2-ylsulfanylpropanamide —— C14H22N2O2S
    N-[(2R)-2-hydroxy-2,3-dimethylbutyl]-3-pyridin-2-ylsulfanylpropanamide
    —— N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-(1-methyltetrazol-5-yl)sulfanylacetamide —— C10H16N6OS
    N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-(1-methyltetrazol-5-yl)sulfanylacetamide
    —— 2-[(5-anilino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(1S,2R,3S)-2,3-dimethylcyclohexyl]acetamide —— C18H24N4OS2
    2-[(5-anilino-1,3,4-thiadiazol-2-yl)sulfanyl]-N-[(1S,2R,3S)-2,3-dimethylcyclohexyl]acetamide
    —— (2R)-3-methyl-2-[4-(3-pyridin-2-ylsulfanylpropanoyl)piperazin-1-yl]butanenitrile —— C17H24N4OS
    (2R)-3-methyl-2-[4-(3-pyridin-2-ylsulfanylpropanoyl)piperazin-1-yl]butanenitrile
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-N-(2-methylpropyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide —— C12H21N5O3S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-N-(2-methylpropyl)-2-(1-methyltetrazol-5-yl)sulfanylacetamide
    —— 2-(4-bromophenyl)sulfanyl-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylacetamide —— C13H16BrNO3S2
    2-(4-bromophenyl)sulfanyl-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methylacetamide
    —— N-[(R)-(3-chlorophenyl)-cyanomethyl]-3-pyridin-2-ylsulfanylpropanamide —— C16H14ClN3OS
    N-[(R)-(3-chlorophenyl)-cyanomethyl]-3-pyridin-2-ylsulfanylpropanamide
    —— 2-[[4-amino-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-propylacetamide —— C16H23N5O4S2
    2-[[4-amino-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-propylacetamide
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[5-[(5S)-5-ethyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide —— C21H28N4O3S3
    N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[5-[(5S)-5-ethyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
    —— N-[(S)-(3-chlorophenyl)-cyanomethyl]-3-pyridin-2-ylsulfanylpropanamide —— C16H14ClN3OS
    N-[(S)-(3-chlorophenyl)-cyanomethyl]-3-pyridin-2-ylsulfanylpropanamide
    —— (2S)-3-methyl-2-[4-(3-pyridin-2-ylsulfanylpropanoyl)piperazin-1-yl]butanenitrile —— C17H24N4OS
    (2S)-3-methyl-2-[4-(3-pyridin-2-ylsulfanylpropanoyl)piperazin-1-yl]butanenitrile
    —— N-cyclohexyl-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide —— C20H24FN3O4S2
    N-cyclohexyl-N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]acetamide
    —— 2-[[4-amino-5-[(2-fluorophenyl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-ethylacetamide —— C17H22FN5O3S2
    2-[[4-amino-5-[(2-fluorophenyl)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-ethylacetamide
    —— N-cyclohexyl-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyltetrazol-5-yl)sulfanylacetamide —— C14H23N5O3S2
    N-cyclohexyl-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyltetrazol-5-yl)sulfanylacetamide
    —— 4-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridine —— C11H16N2S
    4-[[(2R)-piperidin-2-yl]methylsulfanyl]pyridine
    —— 2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-ethylacetamide —— C16H26N4O3S3
    2-[[5-(cyclohexylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(3S)-1,1-dioxothiolan-3-yl]-N-ethylacetamide
    —— (2S)-3-(3-fluorophenyl)sulfanyl-2-hydroxy-2-methylpropanoic acid —— C10H11FO3S
    (2S)-3-(3-fluorophenyl)sulfanyl-2-hydroxy-2-methylpropanoic acid
    —— (2R)-3-(3-fluorophenyl)sulfanyl-2-hydroxy-2-methylpropanoic acid —— C10H11FO3S
    (2R)-3-(3-fluorophenyl)sulfanyl-2-hydroxy-2-methylpropanoic acid
    —— 4-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridine —— C11H16N2S
    4-[[(3R)-piperidin-3-yl]methylsulfanyl]pyridine
    —— 2-[[(2R)-oxan-2-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one —— C13H20N2O2S
    2-[[(2R)-oxan-2-yl]methylsulfanyl]-4-propyl-1H-pyrimidin-6-one
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(5,6-diphenyl-1,2,4-triazin-3-yl)sulfanyl]-N-methylacetamide —— C22H22N4O3S2
    N-[(3S)-1,1-dioxothiolan-3-yl]-2-[(5,6-diphenyl-1,2,4-triazin-3-yl)sulfanyl]-N-methylacetamide
    —— 4-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridine —— C11H16N2S
    4-[[(3S)-piperidin-3-yl]methylsulfanyl]pyridine
    —— 4-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridine —— C11H16N2S
    4-[[(2S)-piperidin-2-yl]methylsulfanyl]pyridine