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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(2-Chlorophenyl)-3-[(2-chlorophenyl)methoxy]-5,7-dimethylchromen-4-one —— C24H18Cl2O3
    2-(2-Chlorophenyl)-3-[(2-chlorophenyl)methoxy]-5,7-dimethylchromen-4-one
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] benzenesulfonate —— C23H17ClO5S
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] benzenesulfonate
    —— 3-[(2-Chloro-6-fluorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one —— C25H20ClFO3
    3-[(2-Chloro-6-fluorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one
    —— 2-[2-(4-methoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-(4-phenoxyphenyl)acetamide —— C32H27NO6
    2-[2-(4-methoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-(4-phenoxyphenyl)acetamide
    —— 2-(2-Chlorophenyl)-5,7-dimethyl-3-[3-(4-methylphenoxy)propoxy]chromen-4-one —— C27H25ClO4
    2-(2-Chlorophenyl)-5,7-dimethyl-3-[3-(4-methylphenoxy)propoxy]chromen-4-one
    —— 2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-(4-ethylphenyl)acetamide —— C27H24ClNO4
    2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-(4-ethylphenyl)acetamide
    —— N-(3-chloro-4-methylphenyl)-2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetamide —— C26H21Cl2NO4
    N-(3-chloro-4-methylphenyl)-2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetamide
    —— [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 3-phenylpropanoate —— C27H24O4
    [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 3-phenylpropanoate
    —— 3-[(4-Fluorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one —— C25H21FO3
    3-[(4-Fluorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one
    —— 2-(2-Chlorophenyl)-5,7-dimethyl-3-[2-(4-nitrophenyl)-2-oxoethoxy]chromen-4-one —— C25H18ClNO6
    2-(2-Chlorophenyl)-5,7-dimethyl-3-[2-(4-nitrophenyl)-2-oxoethoxy]chromen-4-one
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 4-methoxybenzoate —— C25H19ClO5
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 4-methoxybenzoate
    —— 2-(2-Chlorophenyl)-3-[(2-fluorophenyl)methoxy]-5,7-dimethylchromen-4-one —— C24H18ClFO3
    2-(2-Chlorophenyl)-3-[(2-fluorophenyl)methoxy]-5,7-dimethylchromen-4-one
    —— [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 4-fluorobenzoate —— C25H19FO4
    [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 4-fluorobenzoate
    —— [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 4-tert-butylbenzoate —— C30H30O6
    [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 4-tert-butylbenzoate
    —— 2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-[(2-methylphenyl)methoxy]chromen-4-one —— C27H26O5
    2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-[(2-methylphenyl)methoxy]chromen-4-one
    —— 2-[2-(3,4-dimethoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-(4-phenoxyphenyl)acetamide —— C33H29NO7
    2-[2-(3,4-dimethoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-(4-phenoxyphenyl)acetamide
    —— 5,7-Dimethyl-3-[2-(4-methylphenoxy)ethoxy]-2-(4-methylphenyl)chromen-4-one —— C27H26O4
    5,7-Dimethyl-3-[2-(4-methylphenoxy)ethoxy]-2-(4-methylphenyl)chromen-4-one
    —— 3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(2-chlorophenyl)-5,7-dimethylchromen-4-one —— C24H17Cl2FO3
    3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(2-chlorophenyl)-5,7-dimethylchromen-4-one
    —— 2-[5,7-dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(2-propan-2-ylphenyl)acetamide —— C29H29NO4
    2-[5,7-dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(2-propan-2-ylphenyl)acetamide
    —— [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 4-(dimethylamino)benzoate —— C27H25NO4
    [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 4-(dimethylamino)benzoate
    —— [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate —— C28H20O6
    [5,7-Dimethyl-2-(4-methylphenyl)-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate
    —— 5,7-Dimethyl-2-(4-methylphenyl)-3-phenylmethoxychromen-4-one —— C25H22O3
    5,7-Dimethyl-2-(4-methylphenyl)-3-phenylmethoxychromen-4-one
    —— [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 4-chloro-3-nitrobenzoate —— C26H20ClNO8
    [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 4-chloro-3-nitrobenzoate
    —— 2-(2-Chlorophenyl)-5,7-dimethyl-3-(2-phenoxyethoxy)chromen-4-one —— C25H21ClO4
    2-(2-Chlorophenyl)-5,7-dimethyl-3-(2-phenoxyethoxy)chromen-4-one
    —— 2-(3,4-Dimethoxyphenyl)-3-[(2-fluorophenyl)methoxy]-5,7-dimethylchromen-4-one —— C26H23FO5
    2-(3,4-Dimethoxyphenyl)-3-[(2-fluorophenyl)methoxy]-5,7-dimethylchromen-4-one
    —— 2-(2-Chlorophenyl)-3-[2-(4-fluorophenyl)-2-oxoethoxy]-5,7-dimethylchromen-4-one —— C25H18ClFO4
    2-(2-Chlorophenyl)-3-[2-(4-fluorophenyl)-2-oxoethoxy]-5,7-dimethylchromen-4-one
    —— Ethyl 4-[[2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetyl]amino]benzoate —— C28H24ClNO6
    Ethyl 4-[[2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetyl]amino]benzoate
    —— 2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide —— C25H19ClFNO4
    2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide
    —— 5,7-Dimethyl-2-(4-methylphenyl)-3-(2-naphthalen-1-yl-2-oxoethoxy)chromen-4-one —— C30H24O4
    5,7-Dimethyl-2-(4-methylphenyl)-3-(2-naphthalen-1-yl-2-oxoethoxy)chromen-4-one
    —— 2-(2-Chlorophenyl)-3-[2-(4-methoxyphenoxy)ethoxy]-6,8-dimethylchromen-4-one —— C26H23ClO5
    2-(2-Chlorophenyl)-3-[2-(4-methoxyphenoxy)ethoxy]-6,8-dimethylchromen-4-one
    —— 2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-(3,4-dichlorophenyl)acetamide —— C25H18Cl3NO4
    2-[2-(2-chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-(3,4-dichlorophenyl)acetamide
    —— 3-[(4-Bromophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one —— C25H21BrO3
    3-[(4-Bromophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one
    —— 2-(4-Methoxyphenyl)-6,8-dimethyl-3-(2-naphthalen-1-yl-2-oxoethoxy)chromen-4-one —— C30H24O5
    2-(4-Methoxyphenyl)-6,8-dimethyl-3-(2-naphthalen-1-yl-2-oxoethoxy)chromen-4-one
    —— 5,7-Dimethyl-2-(4-methylphenyl)-3-[(4-nitrophenyl)methoxy]chromen-4-one —— C25H21NO5
    5,7-Dimethyl-2-(4-methylphenyl)-3-[(4-nitrophenyl)methoxy]chromen-4-one
    —— 2-(2-Chlorophenyl)-3-[(3,4-dichlorophenyl)methoxy]-5,7-dimethylchromen-4-one —— C24H17Cl3O3
    2-(2-Chlorophenyl)-3-[(3,4-dichlorophenyl)methoxy]-5,7-dimethylchromen-4-one
    —— 2-(3,4-Dimethoxyphenyl)-3-[(2-fluorophenyl)methoxy]-6,8-dimethylchromen-4-one —— C26H23FO5
    2-(3,4-Dimethoxyphenyl)-3-[(2-fluorophenyl)methoxy]-6,8-dimethylchromen-4-one
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 3,4-dimethoxybenzoate —— C26H21ClO6
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 3,4-dimethoxybenzoate
    —— 2-(2-Chlorophenyl)-5,7-dimethyl-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one —— C26H23ClO4
    2-(2-Chlorophenyl)-5,7-dimethyl-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one
    —— 2-(3,4-Dimethoxyphenyl)-6,8-dimethyl-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one —— C28H28O6
    2-(3,4-Dimethoxyphenyl)-6,8-dimethyl-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one
    —— [2-(2-Chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl] 1-benzofuran-2-carboxylate —— C26H17ClO5
    [2-(2-Chlorophenyl)-6,8-dimethyl-4-oxochromen-3-yl] 1-benzofuran-2-carboxylate
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 1-benzofuran-2-carboxylate —— C26H17ClO5
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 1-benzofuran-2-carboxylate
    —— 2-(2-Chlorophenyl)-3-[(3-chlorophenyl)methoxy]-5,7-dimethylchromen-4-one —— C24H18Cl2O3
    2-(2-Chlorophenyl)-3-[(3-chlorophenyl)methoxy]-5,7-dimethylchromen-4-one
    —— [2-(3,4-Dimethoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl] 2-bromobenzoate —— C26H21BrO6
    [2-(3,4-Dimethoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl] 2-bromobenzoate
    —— 2-(2-Chlorophenyl)-3-[(2,4-dichlorophenyl)methoxy]-5,7-dimethylchromen-4-one —— C24H17Cl3O3
    2-(2-Chlorophenyl)-3-[(2,4-dichlorophenyl)methoxy]-5,7-dimethylchromen-4-one
    —— 2-[2-(4-methoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-[3-(trifluoromethyl)phenyl]acetamide —— C27H22F3NO5
    2-[2-(4-methoxyphenyl)-6,8-dimethyl-4-oxochromen-3-yl]oxy-N-[3-(trifluoromethyl)phenyl]acetamide
    —— 2-(3,4-dimethoxyphenyl)-6,8-dimethyl-3-[(2R)-1-oxo-1-phenylpropan-2-yl]oxychromen-4-one —— C28H26O6
    2-(3,4-dimethoxyphenyl)-6,8-dimethyl-3-[(2R)-1-oxo-1-phenylpropan-2-yl]oxychromen-4-one
    —— 2-(2-Chlorophenyl)-3-[(4-chlorophenyl)methoxy]-5,7-dimethylchromen-4-one —— C24H18Cl2O3
    2-(2-Chlorophenyl)-3-[(4-chlorophenyl)methoxy]-5,7-dimethylchromen-4-one
    —— 3-[(4-Bromophenyl)methoxy]-2-(2-chlorophenyl)-5,7-dimethylchromen-4-one —— C24H18BrClO3
    3-[(4-Bromophenyl)methoxy]-2-(2-chlorophenyl)-5,7-dimethylchromen-4-one
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 2-phenoxyacetate —— C25H19ClO5
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] 2-phenoxyacetate
    —— [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] ethyl carbonate —— C20H17ClO5
    [2-(2-Chlorophenyl)-5,7-dimethyl-4-oxochromen-3-yl] ethyl carbonate