黄酮类化合物是一大类天然存在的有机化合物,属于酚类衍生物。它们的分子结构通常包含两个苯环(A和B环)和一个三碳环(C环),形成一个基本骨架。该骨架由多个亚结构组成,包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中,常见于许多蔬菜、水果及中药中。例如,在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基,因此具有一定的亲水性和良好的溶解性,这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定,在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感,容易被氧化,导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注,主要包括:
作为一种天然色素和抗氧化剂,被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性,在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性,已成为新药研发的重要候选目标之一。
中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
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—— | 2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(4-methoxyphenyl)acetamide | —— | C29H29NO5 |
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—— | ethyl (2S)-2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate | —— | C25H28O5 |
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—— | 2-(2-Chlorophenyl)-7-methyl-3-[(4-methylphenyl)methoxy]chromen-4-one | —— | C24H19ClO3 |
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—— | 2-[2-(4-Tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetic acid | —— | C22H22O5 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 4-bromobenzoate | —— | C23H14BrClO4 |
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—— | (2R)-2-[2-(4-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxybutanoate | —— | C20H16ClO5- |
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—— | Methyl 4-[[2-(4-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxymethyl]benzoate | —— | C25H19ClO5 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 3,4,5-trimethoxybenzoate | —— | C26H21ClO7 |
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—— | 2-[2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(1,3-thiazol-2-yl)acetamide | —— | C21H15ClN2O4S |
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—— | (2R)-2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid | —— | C23H24O5 |
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—— | 2-(4-Tert-butylphenyl)-7-methyl-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one | —— | C29H30O4 |
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—— | 2-(4-Tert-butylphenyl)-3-[2-(2,4-dichlorophenyl)-2-oxoethoxy]-7-methylchromen-4-one | —— | C28H24Cl2O4 |
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—— | [2-(4-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 2-phenylacetate | —— | C24H17ClO4 |
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—— | 2-[2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(3,4-dimethoxyphenyl)acetamide | —— | C26H22ClNO6 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 4-fluorobenzoate | —— | C23H14ClFO4 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] furan-2-carboxylate | —— | C21H13ClO5 |
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—— | 2-[7-methyl-2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(4-phenoxyphenyl)acetamide | —— | C31H25NO5 |
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—— | 2-[2-(4-Tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetonitrile | —— | C22H21NO3 |
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—— | N-(3-chloro-4-methoxyphenyl)-2-[2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide | —— | C25H19Cl2NO5 |
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—— | 2-(4-Tert-butylphenyl)-7-methyl-3-[(4-nitrophenyl)methoxy]chromen-4-one | —— | C27H25NO5 |
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—— | 2-(4-Tert-butylphenyl)-3-[(3,4-dichlorophenyl)methoxy]-7-methylchromen-4-one | —— | C27H24Cl2O3 |
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—— | Ethyl 4-[[2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetyl]amino]benzoate | —— | C31H31NO6 |
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—— | 2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(3,4-dimethoxyphenyl)acetamide | —— | C30H31NO6 |
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—— | Methyl 4-[[2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxymethyl]benzoate | —— | C25H19ClO5 |
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—— | Benzyl 2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate | —— | C29H28O5 |
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—— | [2-(4-Tert-butylphenyl)-7-methyl-4-oxochromen-3-yl] pyridine-3-carboxylate | —— | C26H23NO4 |
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—— | [2-(4-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] pentanoate | —— | C21H19ClO4 |
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—— | 2-(4-Tert-butylphenyl)-3-[(4-fluorophenyl)methoxy]-7-methylchromen-4-one | —— | C27H25FO3 |
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—— | 2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide | —— | C28H33NO4 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 4-(dimethylamino)benzoate | —— | C25H20ClNO4 |
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—— | [2-(4-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 3,5-dimethoxybenzoate | —— | C25H19ClO6 |
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—— | methyl (2R)-2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate | —— | C24H26O5 |
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—— | (2S)-2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate | —— | C23H23O5- |
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—— | 2-(4-Chlorophenyl)-7-methyl-3-[(2-methylphenyl)methoxy]chromen-4-one | —— | C24H19ClO3 |
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—— | 2-[2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(furan-2-ylmethyl)acetamide | —— | C23H18ClNO5 |
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—— | [2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl] (E)-3-(4-chlorophenyl)prop-2-enoate | —— | C29H25ClO4 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] thiophene-2-carboxylate | —— | C21H13ClO4S |
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—— | 2-(4-Tert-butylphenyl)-3-[(2,4-dichlorophenyl)methoxy]-7-methylchromen-4-one | —— | C27H24Cl2O3 |
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—— | 2-(2-Chlorophenyl)-3-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethoxy]-7-methylchromen-4-one | —— | C26H19ClO6 |
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—— | 2-[2-(2-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide | —— | C28H26ClNO6 |
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—— | 2-[2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide | —— | C18H14ClNO4 |
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—— | (2S)-2-[2-(4-tert-butylphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid | —— | C23H24O5 |
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—— | [2-(4-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] methyl carbonate | —— | C18H13ClO5 |
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—— | [2-(4-Tert-butylphenyl)-7-methyl-4-oxochromen-3-yl] 4-(dimethylamino)benzoate | —— | C29H29NO4 |
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—— | methyl (2S)-2-[2-(4-chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxy-3-oxobutanoate | —— | C21H17ClO6 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 4-methoxybenzoate | —— | C24H17ClO5 |
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—— | 2-(2-Chlorophenyl)-7-methyl-3-[(4-nitrophenyl)methoxy]chromen-4-one | —— | C23H16ClNO5 |
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—— | 2-[2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl]oxyacetic acid | —— | C18H13ClO5 |
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—— | [2-(2-Chlorophenyl)-7-methyl-4-oxochromen-3-yl] 2,4-dichlorobenzoate | —— | C23H13Cl3O4 |
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—— | 2-(2-Chlorophenyl)-7-methyl-3-(2-morpholin-4-yl-2-oxoethoxy)chromen-4-one | —— | C22H20ClNO5 |
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