黄酮类化合物是一大类天然存在的有机化合物,属于酚类衍生物。它们的分子结构通常包含两个苯环(A和B环)和一个三碳环(C环),形成一个基本骨架。该骨架由多个亚结构组成,包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中,常见于许多蔬菜、水果及中药中。例如,在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基,因此具有一定的亲水性和良好的溶解性,这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定,在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感,容易被氧化,导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注,主要包括:
作为一种天然色素和抗氧化剂,被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性,在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性,已成为新药研发的重要候选目标之一。
中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
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—— | [2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl] (E)-3-(3-nitrophenyl)prop-2-enoate | —— | C26H19NO7 |
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—— | Ethyl 2-[[2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxyacetyl]amino]-4,5-dimethylthiophene-3-carboxylate | —— | C27H24ClNO6S |
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—— | [2-(4-Methoxyphenyl)-6-methyl-4-oxochromen-3-yl] 3-chlorobenzoate | —— | C24H17ClO5 |
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—— | 2-Phenylethyl 2-[2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl]oxyacetate | —— | C27H24O6 |
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—— | Ethyl 4-[[2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxyacetyl]amino]benzoate | —— | C27H22ClNO6 |
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—— | [2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl] (E)-3-(4-tert-butylphenyl)prop-2-enoate | —— | C30H28O5 |
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—— | 2-(4-Methoxyphenyl)-6-methyl-3-[(2-methylphenyl)methoxy]chromen-4-one | —— | C25H22O4 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide | —— | C25H17ClF3NO4 |
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—— | N-(3-chloro-4-methylphenyl)-2-[2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl]oxyacetamide | —— | C26H22ClNO5 |
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—— | [2-(4-Methoxyphenyl)-6-methyl-4-oxochromen-3-yl] 2-phenoxyacetate | —— | C25H20O6 |
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—— | ethyl (2R)-2-[2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl]oxypropanoate | —— | C22H22O6 |
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—— | [2-(4-Methoxyphenyl)-6-methyl-4-oxochromen-3-yl] 2,2-dimethylpropanoate | —— | C22H22O5 |
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—— | N-(2-chlorophenyl)-2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxyacetamide | —— | C24H17Cl2NO4 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(3,4-dimethylphenyl)acetamide | —— | C26H22ClNO4 |
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—— | [2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl] (2S)-2-(2,4-dichlorophenoxy)propanoate | —— | C26H20Cl2O6 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(4-ethoxyphenyl)acetamide | —— | C26H22ClNO5 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(2,5-dimethylphenyl)acetamide | —— | C26H22ClNO4 |
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—— | Methyl 2-[[2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxyacetyl]amino]benzoate | —— | C26H20ClNO6 |
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—— | 2-[2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide | —— | C26H20F3NO5 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide | —— | C24H17ClFNO4 |
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—— | [2-(4-Methoxyphenyl)-6-methyl-4-oxochromen-3-yl] benzenesulfonate | —— | C23H18O6S |
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—— | [2-(4-Methoxyphenyl)-6-methyl-4-oxochromen-3-yl] 4-nitrobenzoate | —— | C24H17NO7 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(4-methoxyphenyl)acetamide | —— | C25H20ClNO5 |
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—— | [2-(4-methoxyphenyl)-6-methyl-4-oxochromen-3-yl] (2S)-2-(1,3-dioxoisoindol-2-yl)propanoate | —— | C28H21NO7 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(4-methylphenyl)acetamide | —— | C25H20ClNO4 |
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—— | 3-[(4-Chlorophenyl)methoxy]-2-(4-methoxyphenyl)-6-methylchromen-4-one | —— | C24H19ClO4 |
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—— | [4-[[2-(4-methoxyphenyl)-6-methylchromen-4-ylidene]amino]phenyl] (E)-3-(3-nitrophenyl)prop-2-enoate | —— | C32H24N2O6 |
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—— | N-[6-Bromo-2-(4-methoxyphenyl)-4H-chromen-4-ylidene]-3,4-dimethoxyaniline | —— | C24H20BrNO4 |
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—— | 6-bromo-N-(4-chlorophenyl)-2-(4-methoxyphenyl)chromen-4-imine | —— | C22H15BrClNO2 |
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—— | [4-[[2-(4-methoxyphenyl)-6-methylchromen-4-ylidene]amino]phenyl] (E)-3-phenylprop-2-enoate | —— | C32H25NO4 |
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—— | [4-[[2-(4-Methoxyphenyl)-6-methylchromen-4-ylidene]amino]phenyl] 3-(1,3-dioxoisoindol-2-yl)propanoate | —— | C34H26N2O6 |
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—— | 4-[[6-Ethyl-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoic acid | —— | C25H21NO4 |
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—— | N-(3-chlorophenyl)-6-ethyl-2-(4-methoxyphenyl)chromen-4-imine | —— | C24H20ClNO2 |
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—— | N-(3,4-dichlorophenyl)-6-ethyl-2-(4-methoxyphenyl)chromen-4-imine | —— | C24H19Cl2NO2 |
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—— | 4-[[6-Ethyl-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoate | —— | C25H20NO4- |
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—— | [4-[[2-(4-Methoxyphenyl)-6-methylchromen-4-ylidene]amino]phenyl] 2-(1,3-dioxoisoindol-2-yl)acetate | —— | C33H24N2O6 |
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—— | 6-ethyl-2-(4-methoxyphenyl)-N-(3-nitrophenyl)chromen-4-imine | —— | C24H20N2O4 |
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—— | 6-ethyl-2-(4-methoxyphenyl)-N-phenylchromen-4-imine | —— | C24H21NO2 |
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—— | 6-bromo-N-(4-bromophenyl)-2-(4-methoxyphenyl)chromen-4-imine | —— | C22H15Br2NO2 |
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—— | 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(2-propan-2-ylphenyl)acetamide | —— | C27H24ClNO4 |
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—— | 3-[(4-Bromophenyl)methoxy]-2-(4-chlorophenyl)-6-methylchromen-4-one | —— | C23H16BrClO3 |
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—— | 2-Methylpropyl 2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxyacetate | —— | C22H21ClO5 |
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—— | [2-(4-Chlorophenyl)-6-methyl-4-oxochromen-3-yl] 4-chlorobenzoate | —— | C23H14Cl2O4 |
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—— | [2-(4-Chlorophenyl)-6-methyl-4-oxochromen-3-yl] 2-methylpropanoate | —— | C20H17ClO4 |
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—— | [2-(4-Chlorophenyl)-6-methyl-4-oxochromen-3-yl] 2,4-dichlorobenzoate | —— | C23H13Cl3O4 |
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—— | 2-[2-(4-tert-butylphenyl)-6-methyl-4-oxochromen-3-yl]oxy-N-(4-ethoxyphenyl)acetamide | —— | C30H31NO5 |
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—— | [2-(4-Chlorophenyl)-6-methyl-4-oxochromen-3-yl] 3,4,5-trimethoxybenzoate | —— | C26H21ClO7 |
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—— | [2-(4-Tert-butylphenyl)-6-methyl-4-oxochromen-3-yl] 3,4-dimethoxybenzoate | —— | C29H28O6 |
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—— | ethyl (2S)-2-[2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl]oxypropanoate | —— | C21H19ClO5 |
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—— | [2-(4-chlorophenyl)-6-methyl-4-oxochromen-3-yl] (E)-3-(4-methoxyphenyl)prop-2-enoate | —— | C26H19ClO5 |
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