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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(3,4-dimethoxyphenyl)-6-methoxy-N-(1,3-thiazol-2-yl)chromen-4-imine —— C21H18N2O4S
    2-(3,4-dimethoxyphenyl)-6-methoxy-N-(1,3-thiazol-2-yl)chromen-4-imine
    —— 2-[[2-(4-Chlorophenyl)-6-methoxychromen-4-ylidene]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile —— C25H19ClN2O2S
    2-[[2-(4-Chlorophenyl)-6-methoxychromen-4-ylidene]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile
    —— 2-(3,4-dimethoxyphenyl)-N-(furan-2-ylmethyl)-6-methoxychromen-4-imine —— C23H21NO5
    2-(3,4-dimethoxyphenyl)-N-(furan-2-ylmethyl)-6-methoxychromen-4-imine
    —— 2-(2-chlorophenyl)-6-methoxy-N-[3-(trifluoromethyl)phenyl]chromen-4-imine —— C23H15ClF3NO2
    2-(2-chlorophenyl)-6-methoxy-N-[3-(trifluoromethyl)phenyl]chromen-4-imine
    —— Ethyl 2-[2-[[2-(4-chlorophenyl)-6-methoxychromen-4-ylidene]amino]-1,3-thiazol-4-yl]acetate —— C23H19ClN2O4S
    Ethyl 2-[2-[[2-(4-chlorophenyl)-6-methoxychromen-4-ylidene]amino]-1,3-thiazol-4-yl]acetate
    —— 2-(4-chlorophenyl)-N-cyclododecyl-6-methoxychromen-4-imine —— C28H34ClNO2
    2-(4-chlorophenyl)-N-cyclododecyl-6-methoxychromen-4-imine
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-(2-morpholin-4-ium-4-ylethyl)chromen-4-imine —— C24H29N2O4+
    6-ethoxy-2-(4-methoxyphenyl)-N-(2-morpholin-4-ium-4-ylethyl)chromen-4-imine
    —— 2-(4-chlorophenyl)-N-(2,4-dimethoxyphenyl)-6-methoxychromen-4-imine —— C24H20ClNO4
    2-(4-chlorophenyl)-N-(2,4-dimethoxyphenyl)-6-methoxychromen-4-imine
    —— 2-(4-chlorophenyl)-N-(2-ethoxyphenyl)-6-methoxychromen-4-imine —— C24H20ClNO3
    2-(4-chlorophenyl)-N-(2-ethoxyphenyl)-6-methoxychromen-4-imine
    —— 2-(4-chlorophenyl)-6-methoxy-N-(4-methylphenyl)chromen-4-imine —— C23H18ClNO2
    2-(4-chlorophenyl)-6-methoxy-N-(4-methylphenyl)chromen-4-imine
    —— 6-methoxy-2-(4-methoxyphenyl)-N-(4-methyl-1,3-benzothiazol-2-yl)chromen-4-imine —— C25H20N2O3S
    6-methoxy-2-(4-methoxyphenyl)-N-(4-methyl-1,3-benzothiazol-2-yl)chromen-4-imine
    —— 2-(4-chlorophenyl)-6-methoxy-N-(3-methoxyphenyl)chromen-4-imine —— C23H18ClNO3
    2-(4-chlorophenyl)-6-methoxy-N-(3-methoxyphenyl)chromen-4-imine
    —— 3-[[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]phenol —— C24H21NO5
    3-[[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]phenol
    —— 2-(3,4-dimethoxyphenyl)-6-methoxy-N-pyridin-1-ium-2-ylchromen-4-imine —— C23H21N2O4+
    2-(3,4-dimethoxyphenyl)-6-methoxy-N-pyridin-1-ium-2-ylchromen-4-imine
    —— 2-(4-chlorophenyl)-N-(2-ethylphenyl)-6-methoxychromen-4-imine —— C24H20ClNO2
    2-(4-chlorophenyl)-N-(2-ethylphenyl)-6-methoxychromen-4-imine
    —— 2-(3,4-dimethoxyphenyl)-6-methoxy-N-(pyridin-3-ylmethyl)chromen-4-imine —— C24H22N2O4
    2-(3,4-dimethoxyphenyl)-6-methoxy-N-(pyridin-3-ylmethyl)chromen-4-imine
    —— Ethyl 2-[(6-methoxy-2-phenylchromen-4-ylidene)amino]-4-methyl-1,3-thiazole-5-carboxylate —— C23H20N2O4S
    Ethyl 2-[(6-methoxy-2-phenylchromen-4-ylidene)amino]-4-methyl-1,3-thiazole-5-carboxylate
    —— 2-(4-chlorophenyl)-6-methoxy-N-phenylchromen-4-imine —— C22H16ClNO2
    2-(4-chlorophenyl)-6-methoxy-N-phenylchromen-4-imine
    —— 4-[[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]phenol —— C24H21NO5
    4-[[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]phenol
    —— 1-[2-[[2-(2-Chlorophenyl)-6-methoxychromen-4-ylidene]amino]-4-methyl-1,3-thiazol-5-yl]ethanone —— C22H17ClN2O3S
    1-[2-[[2-(2-Chlorophenyl)-6-methoxychromen-4-ylidene]amino]-4-methyl-1,3-thiazol-5-yl]ethanone
    —— 2-[[2-(4-Chlorophenyl)-6-methoxychromen-4-ylidene]amino]benzamide —— C23H17ClN2O3
    2-[[2-(4-Chlorophenyl)-6-methoxychromen-4-ylidene]amino]benzamide
    —— 1-[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]pyrrolidin-1-ium —— C21H22NO3+
    1-[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]pyrrolidin-1-ium
    —— 1-[2-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-4-methyl-1,3-thiazol-5-yl]ethanone —— C23H20N2O4S
    1-[2-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-4-methyl-1,3-thiazol-5-yl]ethanone
    —— N-(3,4-dichlorophenyl)-6-methoxy-2-(4-methoxyphenyl)chromen-4-imine —— C23H17Cl2NO3
    N-(3,4-dichlorophenyl)-6-methoxy-2-(4-methoxyphenyl)chromen-4-imine
    —— 2-(4-chlorophenyl)-6-methoxy-N-pyridin-2-ylchromen-4-imine —— C21H15ClN2O2
    2-(4-chlorophenyl)-6-methoxy-N-pyridin-2-ylchromen-4-imine
    —— 2-[(6-Methoxy-2-phenylchromen-4-ylidene)amino]ethyl-dimethylazanium —— C20H23N2O2+
    2-[(6-Methoxy-2-phenylchromen-4-ylidene)amino]ethyl-dimethylazanium
    —— Ethyl 3-[(6-methoxy-2-phenylchromen-4-ylidene)amino]benzoate —— C25H21NO4
    Ethyl 3-[(6-methoxy-2-phenylchromen-4-ylidene)amino]benzoate
    —— 2-(4-chlorophenyl)-6-methoxy-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)chromen-4-imine —— C21H18ClN3O2S
    2-(4-chlorophenyl)-6-methoxy-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)chromen-4-imine
    —— 2-[[6-methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-N-(2-methylpropyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide —— C30H32N2O4S
    2-[[6-methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-N-(2-methylpropyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
    —— 2-(4-chlorophenyl)-6-methoxy-N-(2-methylpropyl)chromen-4-imine —— C20H20ClNO2
    2-(4-chlorophenyl)-6-methoxy-N-(2-methylpropyl)chromen-4-imine
    —— (2S)-1-[[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]propan-2-ol —— C21H23NO5
    (2S)-1-[[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]propan-2-ol
    —— 4-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,5-dimethyl-2-phenylpyrazol-3-one —— C28H25N3O4
    4-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,5-dimethyl-2-phenylpyrazol-3-one
    —— 2-(3,4-dimethoxyphenyl)-6-methoxy-N-phenylchromen-4-imine —— C24H21NO4
    2-(3,4-dimethoxyphenyl)-6-methoxy-N-phenylchromen-4-imine
    —— 4-[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]morpholin-4-ium —— C22H24NO5+
    4-[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]morpholin-4-ium
    —— 4-[[2-(4-chlorophenyl)-6-methoxychromen-4-ylidene]amino]-N,N-dimethylaniline —— C24H21ClN2O2
    4-[[2-(4-chlorophenyl)-6-methoxychromen-4-ylidene]amino]-N,N-dimethylaniline
    —— 2-(2-chlorophenyl)-N-cyclohexyl-6-methoxychromen-4-imine —— C22H22ClNO2
    2-(2-chlorophenyl)-N-cyclohexyl-6-methoxychromen-4-imine
    —— Ethyl 4-[[6-ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoate —— C27H25NO5
    Ethyl 4-[[6-ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoate
    —— 2-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]ethanol —— C19H19NO4
    2-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]ethanol
    —— 6-methoxy-N-(2-methoxyphenyl)-2-(4-methoxyphenyl)chromen-4-imine —— C24H21NO4
    6-methoxy-N-(2-methoxyphenyl)-2-(4-methoxyphenyl)chromen-4-imine
    —— Benzyl-[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]-methylazanium —— C26H26NO4+
    Benzyl-[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]-methylazanium
    —— 2-[[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]ethyl-dimethylazanium —— C22H27N2O4+
    2-[[2-(3,4-Dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]ethyl-dimethylazanium
    —— 6-methoxy-N-(3-nitrophenyl)-2-phenylchromen-4-imine —— C22H16N2O4
    6-methoxy-N-(3-nitrophenyl)-2-phenylchromen-4-imine
    —— 2-(2-chlorophenyl)-6-methoxy-N-naphthalen-1-ylchromen-4-imine —— C26H18ClNO2
    2-(2-chlorophenyl)-6-methoxy-N-naphthalen-1-ylchromen-4-imine
    —— 3-[[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]-N,N-dimethylpropan-1-amine —— C23H28N2O4
    3-[[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]-N,N-dimethylpropan-1-amine
    —— Ethyl 2-[2-[(6-methoxy-2-phenylchromen-4-ylidene)amino]-1,3-thiazol-4-yl]acetate —— C23H20N2O4S
    Ethyl 2-[2-[(6-methoxy-2-phenylchromen-4-ylidene)amino]-1,3-thiazol-4-yl]acetate
    —— 3-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoic acid —— C24H19NO5
    3-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoic acid
    —— 4-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]phenol —— C23H19NO4
    4-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]phenol
    —— 4-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzenesulfonamide —— C23H20N2O5S
    4-[[6-Methoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzenesulfonamide
    —— N-(4-chloro-3-nitrophenyl)-2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-imine —— C24H19ClN2O6
    N-(4-chloro-3-nitrophenyl)-2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-imine
    —— 2-(2-chlorophenyl)-6-methoxy-N-(4-methoxyphenyl)chromen-4-imine —— C23H18ClNO3
    2-(2-chlorophenyl)-6-methoxy-N-(4-methoxyphenyl)chromen-4-imine