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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 6-Chloro-2-(2-chlorophenyl)-3-[(4-chlorophenyl)methoxy]chromen-4-one —— C22H13Cl3O3
    6-Chloro-2-(2-chlorophenyl)-3-[(4-chlorophenyl)methoxy]chromen-4-one
    —— (2R)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-phenylpropanamide —— C24H17Cl2NO4
    (2R)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-phenylpropanamide
    —— 3-[2-(1-Benzofuran-2-yl)-2-oxoethoxy]-6-chloro-2-(2-chlorophenyl)chromen-4-one —— C25H14Cl2O5
    3-[2-(1-Benzofuran-2-yl)-2-oxoethoxy]-6-chloro-2-(2-chlorophenyl)chromen-4-one
    —— 6-Chloro-2-(2-chlorophenyl)-3-[(3-chlorophenyl)methoxy]chromen-4-one —— C22H13Cl3O3
    6-Chloro-2-(2-chlorophenyl)-3-[(3-chlorophenyl)methoxy]chromen-4-one
    —— [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] acetate —— C17H10Cl2O4
    [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] acetate
    —— 2-(4-tert-butylphenyl)-6-chloro-3-[2-(1H-indol-3-yl)-2-oxoethoxy]chromen-4-one —— C29H24ClNO4
    2-(4-tert-butylphenyl)-6-chloro-3-[2-(1H-indol-3-yl)-2-oxoethoxy]chromen-4-one
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2-fluorophenyl)acetamide —— C23H14Cl2FNO4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2-fluorophenyl)acetamide
    —— N-(3-acetylphenyl)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxyacetamide —— C25H17Cl2NO5
    N-(3-acetylphenyl)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxyacetamide
    —— [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 3-methylbenzoate —— C23H14Cl2O4
    [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 3-methylbenzoate
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2-chlorophenyl)acetamide —— C23H14Cl3NO4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2-chlorophenyl)acetamide
    —— [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate —— C25H12Cl2O6
    [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate
    —— (2R)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(4-chlorophenyl)propanamide —— C28H25Cl2NO4
    (2R)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(4-chlorophenyl)propanamide
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,4-dimethylphenyl)acetamide —— C25H19Cl2NO4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,4-dimethylphenyl)acetamide
    —— 2-(4-Tert-butylphenyl)-6-chloro-3-[(3-chlorophenyl)methoxy]chromen-4-one —— C26H22Cl2O3
    2-(4-Tert-butylphenyl)-6-chloro-3-[(3-chlorophenyl)methoxy]chromen-4-one
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(3-chloro-4-methylphenyl)acetamide —— C24H16Cl3NO4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(3-chloro-4-methylphenyl)acetamide
    —— [6-Chloro-2-(4-methylphenyl)-4-oxochromen-3-yl] 2-phenylacetate —— C24H17ClO4
    [6-Chloro-2-(4-methylphenyl)-4-oxochromen-3-yl] 2-phenylacetate
    —— 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(3,4-dimethylphenyl)acetamide —— C29H28ClNO4
    2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(3,4-dimethylphenyl)acetamide
    —— 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(2-ethoxyphenyl)acetamide —— C29H28ClNO5
    2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(2-ethoxyphenyl)acetamide
    —— 6-Chloro-2-(2-chlorophenyl)-3-(2-morpholin-4-yl-2-oxoethoxy)chromen-4-one —— C21H17Cl2NO5
    6-Chloro-2-(2-chlorophenyl)-3-(2-morpholin-4-yl-2-oxoethoxy)chromen-4-one
    —— 2-Methylpropyl 2-[[2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxyacetyl]amino]-4-methyl-1,3-thiazole-5-carboxylate —— C26H22Cl2N2O6S
    2-Methylpropyl 2-[[2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxyacetyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
    —— (2R)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,6-diethylphenyl)propanamide —— C28H25Cl2NO4
    (2R)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,6-diethylphenyl)propanamide
    —— 6-Chloro-2-(2-chlorophenyl)-3-[(1-methylpyrazol-4-yl)methoxy]chromen-4-one —— C20H14Cl2N2O3
    6-Chloro-2-(2-chlorophenyl)-3-[(1-methylpyrazol-4-yl)methoxy]chromen-4-one
    —— [6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] (E)-3-phenylprop-2-enoate —— C24H14Cl2O4
    [6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] (E)-3-phenylprop-2-enoate
    —— 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-[(1R)-1-phenylethyl]acetamide —— C29H28ClNO4
    2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-[(1R)-1-phenylethyl]acetamide
    —— 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)acetamide —— C32H30ClN3O5
    2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)acetamide
    —— 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(4-ethoxyphenyl)acetamide —— C29H28ClNO5
    2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(4-ethoxyphenyl)acetamide
    —— (2S)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,4,6-trimethylphenyl)propanamide —— C27H23Cl2NO4
    (2S)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,4,6-trimethylphenyl)propanamide
    —— (2S)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-chlorophenyl)propanamide —— C24H16Cl3NO4
    (2S)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-chlorophenyl)propanamide
    —— (2S)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,6-diethylphenyl)propanamide —— C28H25Cl2NO4
    (2S)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,6-diethylphenyl)propanamide
    —— 2-(4-Tert-butylphenyl)-6-chloro-3-phenacyloxychromen-4-one —— C27H23ClO4
    2-(4-Tert-butylphenyl)-6-chloro-3-phenacyloxychromen-4-one
    —— Propan-2-yl 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetate —— C24H25ClO5
    Propan-2-yl 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetate
    —— 2-(4-Tert-butylphenyl)-6-chloro-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one —— C28H27ClO4
    2-(4-Tert-butylphenyl)-6-chloro-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(3,5-dichlorophenyl)acetamide —— C23H13Cl4NO4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(3,5-dichlorophenyl)acetamide
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide —— C23H14Cl2FNO4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide —— C24H14Cl2F3NO4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-[4-(dimethylamino)phenyl]acetamide —— C25H20Cl2N2O4
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-[4-(dimethylamino)phenyl]acetamide
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamide —— C26H18Cl2N2O4S
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamide
    —— 6-Chloro-3-[2-(4-chlorophenoxy)ethoxy]-2-(2-chlorophenyl)chromen-4-one —— C23H15Cl3O4
    6-Chloro-3-[2-(4-chlorophenoxy)ethoxy]-2-(2-chlorophenyl)chromen-4-one
    —— 2-(4-Tert-butylphenyl)-6-chloro-3-(2-morpholin-4-yl-2-oxoethoxy)chromen-4-one —— C25H26ClNO5
    2-(4-Tert-butylphenyl)-6-chloro-3-(2-morpholin-4-yl-2-oxoethoxy)chromen-4-one
    —— 6-chloro-2-(2-chlorophenyl)-3-[(6-nitro-4H-1,3-benzodioxin-8-yl)methoxy]chromen-4-one —— C24H15Cl2NO7
    6-chloro-2-(2-chlorophenyl)-3-[(6-nitro-4H-1,3-benzodioxin-8-yl)methoxy]chromen-4-one
    —— 2-Phenoxyethyl 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxyacetate —— C25H18Cl2O6
    2-Phenoxyethyl 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxyacetate
    —— 2-[2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetate —— C21H18ClO5-
    2-[2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetate
    —— 2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,4-dimethoxyphenyl)acetamide —— C25H19Cl2NO6
    2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2,4-dimethoxyphenyl)acetamide
    —— 6-Chloro-2-(2-chlorophenyl)-3-methoxychromen-4-one —— C16H10Cl2O3
    6-Chloro-2-(2-chlorophenyl)-3-methoxychromen-4-one
    —— 6-Chloro-2-(2-chlorophenyl)-3-(3-naphthalen-1-yloxypropoxy)chromen-4-one —— C28H20Cl2O4
    6-Chloro-2-(2-chlorophenyl)-3-(3-naphthalen-1-yloxypropoxy)chromen-4-one
    —— Ethyl 5-[[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxymethyl]furan-2-carboxylate —— C23H16Cl2O6
    Ethyl 5-[[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxymethyl]furan-2-carboxylate
    —— 6-Chloro-2-(2-chlorophenyl)-3-ethoxychromen-4-one —— C17H12Cl2O3
    6-Chloro-2-(2-chlorophenyl)-3-ethoxychromen-4-one
    —— (2R)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(2-chlorophenyl)propanamide —— C28H25Cl2NO4
    (2R)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(2-chlorophenyl)propanamide
    —— [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] thiophene-2-carboxylate —— C20H10Cl2O4S
    [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] thiophene-2-carboxylate
    —— Methyl 3-[[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxymethyl]benzoate —— C24H16Cl2O5
    Methyl 3-[[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxymethyl]benzoate