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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (6,7-Dimethyl-4-oxo-2-phenylchromen-3-yl) 3,4-dimethoxybenzoate —— C26H22O6
    (6,7-Dimethyl-4-oxo-2-phenylchromen-3-yl) 3,4-dimethoxybenzoate
    —— 6,7-Dimethyl-2-phenyl-3-(thiophen-2-ylmethoxy)chromen-4-one —— C22H18O3S
    6,7-Dimethyl-2-phenyl-3-(thiophen-2-ylmethoxy)chromen-4-one
    —— 3-[(4-Chlorophenyl)methoxy]-6,7-dimethyl-2-phenylchromen-4-one —— C24H19ClO3
    3-[(4-Chlorophenyl)methoxy]-6,7-dimethyl-2-phenylchromen-4-one
    —— 3-[(2,6-Dichlorophenyl)methoxy]-6,7-dimethyl-2-phenylchromen-4-one —— C24H18Cl2O3
    3-[(2,6-Dichlorophenyl)methoxy]-6,7-dimethyl-2-phenylchromen-4-one
    —— 3-[(4-Bromophenyl)methoxy]-6,7-dimethyl-2-phenylchromen-4-one —— C24H19BrO3
    3-[(4-Bromophenyl)methoxy]-6,7-dimethyl-2-phenylchromen-4-one
    —— N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine —— C25H20N4O2
    N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine
    —— 2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-methylchromen-4-one —— C26H26N2O3
    2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-methylchromen-4-one
    —— 2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxychromen-4-one —— C25H24N2O3
    2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxychromen-4-one
    —— Methyl 2-[2-[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C23H21N3O4S
    Methyl 2-[2-[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Methyl 2-[2-[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C24H23N3O5S
    Methyl 2-[2-[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— 2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,7-dimethylchromen-4-one —— C27H28N2O3
    2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,7-dimethylchromen-4-one
    —— 2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-ethylchromen-4-one —— C23H19ClN2O3
    2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-ethylchromen-4-one
    —— 2-(4-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,7-dimethylchromen-4-one —— C23H19ClN2O3
    2-(4-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,7-dimethylchromen-4-one
    —— N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine —— C26H22N4O3
    N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine
    —— 2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,7-dimethylchromen-4-one —— C23H19ClN2O3
    2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,7-dimethylchromen-4-one
    —— N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-2-amine —— C26H21N3O2
    N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-2-amine
    —— 2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-5,7-dimethylchromen-4-one —— C23H19ClN2O3
    2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-5,7-dimethylchromen-4-one
    —— 2-(4-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-ethylchromen-4-one —— C23H19ClN2O3
    2-(4-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-ethylchromen-4-one
    —— N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]-1,3-benzothiazol-2-amine —— C24H19N3O2S
    N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]-1,3-benzothiazol-2-amine
    —— N-[[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine —— C25H19ClN4O3
    N-[[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine
    —— Methyl 2-[2-[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C24H23N3O4S
    Methyl 2-[2-[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine —— C24H17ClN4O2
    N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine
    —— (1H-benzimidazol-2-ylamino)-[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]azanium —— C24H21N4O2+
    (1H-benzimidazol-2-ylamino)-[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]azanium
    —— N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine —— C24H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C25H22N4O3
    N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[6,8-dichloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine —— C25H18Cl2N4O3
    N-[[6,8-dichloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine
    —— N-[[6-chloro-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine —— C26H21ClN4O3
    N-[[6-chloro-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine
    —— 2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-ethylchromen-4-one —— C27H28N2O3
    2-(4-Tert-butylphenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6-ethylchromen-4-one
    —— N-[[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinazolin-4-amine —— C26H22N4O2
    N-[[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinazolin-4-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]-1,3-benzothiazol-2-amine —— C25H21N3O3S
    N-[[2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]-1,3-benzothiazol-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine —— C27H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine
    —— 2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,8-dimethylchromen-4-one —— C23H19ClN2O3
    2-(2-Chlorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)oxy-6,8-dimethylchromen-4-one
    —— N-[[6-chloro-2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine —— C25H19ClN4O2
    N-[[6-chloro-2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinazolin-4-amine
    —— N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C24H20N4O2
    N-[[2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine —— C27H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]quinazolin-4-amine —— C26H22N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]quinazolin-4-amine
    —— N-[[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine —— C26H22N4O2
    N-[[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinazolin-4-amine
    —— Methyl 2-[2-[6,8-dichloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C23H19Cl2N3O5S
    Methyl 2-[2-[6,8-dichloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Methyl 2-[2-[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C25H25N3O5S
    Methyl 2-[2-[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Methyl 2-[2-[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C24H23N3O4S
    Methyl 2-[2-[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— N-[[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinazolin-4-amine —— C27H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinazolin-4-amine
    —— (4E)-6-Bromo-2-(4-methoxyphenyl)-N-[4-(pyrrolidin-1-YL)phenyl]-4H-chromen-4-imine —— C26H23BrN2O2
    (4E)-6-Bromo-2-(4-methoxyphenyl)-N-[4-(pyrrolidin-1-YL)phenyl]-4H-chromen-4-imine
    —— N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine —— C24H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine
    —— Methyl 2-[2-[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C23H20ClN3O5S
    Methyl 2-[2-[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Methyl 2-[2-[2-(4-methoxyphenyl)-5,7-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C24H23N3O4S
    Methyl 2-[2-[2-(4-methoxyphenyl)-5,7-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Methyl 2-[2-[6-ethyl-2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C24H23N3O4S
    Methyl 2-[2-[6-ethyl-2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Methyl 2-[2-[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C25H25N3O5S
    Methyl 2-[2-[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Methyl 2-[2-[6,8-dichloro-2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C22H17Cl2N3O4S
    Methyl 2-[2-[6,8-dichloro-2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— N-[[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine —— C25H26N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]-4,6-dimethylpyrimidin-2-amine
    —— Methyl 2-[2-[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C22H18ClN3O4S
    Methyl 2-[2-[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate