黄酮类化合物是一大类天然存在的有机化合物,属于酚类衍生物。它们的分子结构通常包含两个苯环(A和B环)和一个三碳环(C环),形成一个基本骨架。该骨架由多个亚结构组成,包括黄烷醇、黄酮、黄酮醇等。
生物来源黄酮类化合物广泛存在于植物界中,常见于许多蔬菜、水果及中药中。例如,在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。
化学性质 亲水性与溶解度由于其分子结构中含有多个酚羟基,因此具有一定的亲水性和良好的溶解性,这使得黄酮类化合物在药物设计中扮演重要角色。
稳定性与光敏性大多数黄酮类化合物相对稳定,在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感,容易被氧化,导致颜色变化。
生理活性与药用价值黄酮类化合物因其丰富的生理活性而备受关注,主要包括:
作为一种天然色素和抗氧化剂,被广泛应用于食品加工中以提高其保质期及营养价值。
化妆品行业利用其良好的生物相容性和抗衰老特性,在化妆品配方中应用广泛。
药物开发由于黄酮类化合物展现出广泛的药理活性,已成为新药研发的重要候选目标之一。
中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
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—— | [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 2,2-dimethylpropanoate | —— | C20H16Cl2O4 |
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—— | 6-Chloro-2-(2-chlorophenyl)-3-[3-(4-methylphenoxy)propoxy]chromen-4-one | —— | C25H20Cl2O4 |
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—— | [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 2-(4-nitrophenoxy)acetate | —— | C23H13Cl2NO7 |
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—— | 2-(4-tert-butylphenyl)-6-chloro-3-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethoxy]chromen-4-one | —— | C30H28ClNO4 |
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—— | Cyclohexyl 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetate | —— | C27H29ClO5 |
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—— | (2R)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxypropanoate | —— | C22H20ClO5- |
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—— | (2R)-2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-ethylphenyl)propanamide | —— | C26H21Cl2NO4 |
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—— | 6-Chloro-2-(2-chlorophenyl)-3-[2-(4-ethoxyphenyl)-2-oxoethoxy]chromen-4-one | —— | C25H18Cl2O5 |
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—— | 8-[[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxymethyl]-4H-1,3-benzodioxine-6-carboxylate | —— | C29H24ClO7- |
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—— | 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-[3-(trifluoromethyl)phenyl]acetamide | —— | C28H23ClF3NO4 |
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—— | (2R)-2-[6-chloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(2,5-dichlorophenyl)propanamide | —— | C25H18Cl3NO4 |
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—— | 3-[(4-Bromophenyl)methoxy]-6-chloro-2-(2-chlorophenyl)chromen-4-one | —— | C22H13BrCl2O3 |
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—— | [2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl] 3-(4-nitro-1,3-dioxoisoindol-2-yl)propanoate | —— | C30H23ClN2O8 |
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—— | 2-(4-Tert-butylphenyl)-6-chloro-3-[(2,4-dichlorophenyl)methoxy]chromen-4-one | —— | C26H21Cl3O3 |
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—— | 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(2,4,6-trimethylphenyl)acetamide | —— | C30H30ClNO4 |
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—— | 2-[2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetic acid | —— | C21H19ClO5 |
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—— | (2S)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(4-methylphenyl)propanamide | —— | C29H28ClNO4 |
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—— | 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-[(1S)-1-phenylethyl]acetamide | —— | C29H28ClNO4 |
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—— | [6-Chloro-2-(4-methylphenyl)-4-oxochromen-3-yl] 5-bromopyridine-3-carboxylate | —— | C22H13BrClNO4 |
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—— | 2-(4-Tert-butylphenyl)-6-chloro-3-[(2-methylphenyl)methoxy]chromen-4-one | —— | C27H25ClO3 |
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—— | Ethyl 4-[[2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetyl]amino]benzoate | —— | C30H28ClNO6 |
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—— | Benzyl 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetate | —— | C28H25ClO5 |
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—— | methyl 8-[[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxymethyl]-4H-1,3-benzodioxine-6-carboxylate | —— | C30H27ClO7 |
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—— | (2S)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(2-chlorophenyl)propanamide | —— | C28H25Cl2NO4 |
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—— | [2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl] 3-(4-methylphenoxy)propanoate | —— | C29H27ClO5 |
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—— | [2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl] 4-(dimethylamino)benzoate | —— | C28H26ClNO4 |
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—— | [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 2-cyclohexyl-1,3-dioxoisoindole-5-carboxylate | —— | C30H21Cl2NO6 |
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—— | (2S)-N-(4-bromophenyl)-2-[6-chloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxypropanamide | —— | C25H19BrClNO4 |
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—— | (2S)-2-[6-chloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(2,4,6-trimethylphenyl)propanamide | —— | C28H26ClNO4 |
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—— | Ethyl 2-[[2-[6-chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl]oxyacetyl]amino]-5-phenylthiophene-3-carboxylate | —— | C30H21Cl2NO6S |
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—— | (2S)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-(2,4-dimethylphenyl)propanamide | —— | C30H30ClNO4 |
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—— | (2R)-2-[6-chloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(4-chlorophenyl)propanamide | —— | C25H19Cl2NO4 |
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—— | (2S)-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-phenylpropanamide | —— | C28H26ClNO4 |
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—— | [2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl] 2-(2-methylpropyl)-1,3-dioxoisoindole-5-carboxylate | —— | C32H28ClNO6 |
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—— | (2S)-2-[6-chloro-2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]propanamide | —— | C26H19ClF3NO4 |
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—— | [6-Chloro-2-(4-methylphenyl)-4-oxochromen-3-yl] 2-methylpropanoate | —— | C20H17ClO4 |
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—— | Methyl 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetate | —— | C22H21ClO5 |
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—— | 2-(4-Tert-butylphenyl)-6-chloro-3-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]chromen-4-one | —— | C25H24ClNO4 |
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—— | 2-(4-Tert-butylphenyl)-6-chloro-3-[(4-chlorophenyl)methoxy]chromen-4-one | —— | C26H22Cl2O3 |
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—— | [6-Chloro-2-(4-methylphenyl)-4-oxochromen-3-yl] 1,3-dioxo-2-propan-2-ylisoindole-5-carboxylate | —— | C28H20ClNO6 |
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—— | 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide | —— | C27H30ClNO4 |
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—— | [2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl] 4-fluorobenzoate | —— | C26H20ClFO4 |
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—— | 2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxy-N-[4-(diethylsulfamoyl)phenyl]acetamide | —— | C31H33ClN2O6S |
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—— | [2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl] 3,5-dimethoxybenzoate | —— | C28H25ClO6 |
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—— | N-benzyl-2-[2-(4-tert-butylphenyl)-6-chloro-4-oxochromen-3-yl]oxyacetamide | —— | C28H26ClNO4 |
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—— | 2-(4-Tert-butylphenyl)-6-chloro-3-hydroxychromen-4-one | —— | C19H17ClO3 |
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—— | [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 2,4-dichlorobenzoate | —— | C22H10Cl4O4 |
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—— | [2-(4-Tert-butylphenyl)-6-chloro-4-oxochromen-3-yl] 2-(4-methoxyphenyl)acetate | —— | C28H25ClO5 |
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—— | [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 4-tert-butylbenzoate | —— | C26H20Cl2O4 |
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—— | [6-Chloro-2-(2-chlorophenyl)-4-oxochromen-3-yl] 1,2,3,4-tetrahydroacridine-9-carboxylate | —— | C29H19Cl2NO4 |
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