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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-cyclohexyl-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine —— C24H27NO3
    N-cyclohexyl-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine
    —— N-(3,4-dichlorophenyl)-2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-imine —— C25H21Cl2NO4
    N-(3,4-dichlorophenyl)-2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-imine
    —— 4-Chloro-2-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]phenol —— C25H22ClNO5
    4-Chloro-2-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]phenol
    —— N-(2,4-dichlorophenyl)-2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-imine —— C25H21Cl2NO4
    N-(2,4-dichlorophenyl)-2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-imine
    —— 4-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,5-dimethyl-2-phenylpyrazol-3-one —— C29H27N3O4
    4-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,5-dimethyl-2-phenylpyrazol-3-one
    —— 2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(3-methoxyphenyl)chromen-4-imine —— C26H25NO5
    2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(3-methoxyphenyl)chromen-4-imine
    —— 2-(3,4-dimethoxyphenyl)-6-ethoxy-N-pyridin-2-ylchromen-4-imine —— C24H22N2O4
    2-(3,4-dimethoxyphenyl)-6-ethoxy-N-pyridin-2-ylchromen-4-imine
    —— 4-[[2-(3,4-Dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]phenol —— C25H23NO5
    4-[[2-(3,4-Dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]phenol
    —— N-[2-(3,4-dimethoxyphenyl)ethyl]-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine —— C28H29NO5
    N-[2-(3,4-dimethoxyphenyl)ethyl]-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine
    —— 2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(2-methoxyphenyl)chromen-4-imine —— C26H25NO5
    2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(2-methoxyphenyl)chromen-4-imine
    —— 2-(3,4-dimethoxyphenyl)-6-ethoxy-N-[3-(trifluoromethyl)phenyl]chromen-4-imine —— C26H22F3NO4
    2-(3,4-dimethoxyphenyl)-6-ethoxy-N-[3-(trifluoromethyl)phenyl]chromen-4-imine
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-(4-phenylmethoxyphenyl)chromen-4-imine —— C31H27NO4
    6-ethoxy-2-(4-methoxyphenyl)-N-(4-phenylmethoxyphenyl)chromen-4-imine
    —— (2R)-1-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]propan-2-ol —— C22H25NO5
    (2R)-1-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]propan-2-ol
    —— 2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(pyridin-3-ylmethyl)chromen-4-imine —— C25H24N2O4
    2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(pyridin-3-ylmethyl)chromen-4-imine
    —— 2-(7-methyl-4-oxo-4H-chromen-2-yl)benzoic acid —— C17H12O4
    2-(7-methyl-4-oxo-4H-chromen-2-yl)benzoic acid
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-(6-methyl-1,3-benzothiazol-2-yl)chromen-4-imine —— C26H22N2O3S
    6-ethoxy-2-(4-methoxyphenyl)-N-(6-methyl-1,3-benzothiazol-2-yl)chromen-4-imine
    —— 2-(3,4-dimethoxyphenyl)-6-ethoxy-N-naphthalen-1-ylchromen-4-imine —— C29H25NO4
    2-(3,4-dimethoxyphenyl)-6-ethoxy-N-naphthalen-1-ylchromen-4-imine
    —— 3-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]propyl-diethylazanium —— C25H33N2O3+
    3-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]propyl-diethylazanium
    —— 2-[[6-ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-N,N-dimethylethanamine —— C22H26N2O3
    2-[[6-ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-N,N-dimethylethanamine
    —— 2-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzamide —— C25H22N2O4
    2-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzamide
    —— N-(3,5-dichlorophenyl)-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine —— C24H19Cl2NO3
    N-(3,5-dichlorophenyl)-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine
    —— Ethyl 4-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]benzoate —— C28H27NO6
    Ethyl 4-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]benzoate
    —— N-benzyl-2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-imine —— C26H25NO4
    N-benzyl-2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-imine
    —— 3-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoate —— C25H20NO5-
    3-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoate
    —— 3-[[2-(3,4-Dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]benzoic acid —— C26H23NO6
    3-[[2-(3,4-Dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]benzoic acid
    —— 3-[[2-(3,4-Dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]phenol —— C25H23NO5
    3-[[2-(3,4-Dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]phenol
    —— 2-(2-chlorophenyl)-N-(4-ethoxyphenyl)-6-methoxychromen-4-imine —— C24H20ClNO3
    2-(2-chlorophenyl)-N-(4-ethoxyphenyl)-6-methoxychromen-4-imine
    —— 3-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]propan-1-ol —— C21H23NO4
    3-[[6-Ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]propan-1-ol
    —— 6-ethoxy-N-hexyl-2-(4-methoxyphenyl)chromen-4-imine —— C24H29NO3
    6-ethoxy-N-hexyl-2-(4-methoxyphenyl)chromen-4-imine
    —— Propan-2-yl 4-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]benzoate —— C29H29NO6
    Propan-2-yl 4-[[2-(3,4-dimethoxyphenyl)-6-ethoxychromen-4-ylidene]amino]benzoate
    —— 8-(6,7-Dimethyl-4-oxochromen-2-yl)naphthalene-1-carboxylate —— C22H15O4-
    8-(6,7-Dimethyl-4-oxochromen-2-yl)naphthalene-1-carboxylate
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-[[(2R)-oxolan-2-yl]methyl]chromen-4-imine —— C23H25NO4
    6-ethoxy-2-(4-methoxyphenyl)-N-[[(2R)-oxolan-2-yl]methyl]chromen-4-imine
    —— 2-(4-chlorophenyl)-N-(2-fluorophenyl)-6-methoxychromen-4-imine —— C22H15ClFNO2
    2-(4-chlorophenyl)-N-(2-fluorophenyl)-6-methoxychromen-4-imine
    —— 2-(6,7-Dimethyl-4-oxochromen-2-yl)benzoic acid —— C18H14O4
    2-(6,7-Dimethyl-4-oxochromen-2-yl)benzoic acid
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-propan-2-ylchromen-4-imine —— C21H23NO3
    6-ethoxy-2-(4-methoxyphenyl)-N-propan-2-ylchromen-4-imine
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-[[(2S)-oxolan-2-yl]methyl]chromen-4-imine —— C23H25NO4
    6-ethoxy-2-(4-methoxyphenyl)-N-[[(2S)-oxolan-2-yl]methyl]chromen-4-imine
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-pyridin-2-ylchromen-4-imine —— C23H20N2O3
    6-ethoxy-2-(4-methoxyphenyl)-N-pyridin-2-ylchromen-4-imine
    —— 4-[[2-(2-chlorophenyl)-6-methoxychromen-4-ylidene]amino]-N,N-dimethylaniline —— C24H21ClN2O2
    4-[[2-(2-chlorophenyl)-6-methoxychromen-4-ylidene]amino]-N,N-dimethylaniline
    —— N-(4,5-dimethyl-1,3-thiazol-2-yl)-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine —— C23H22N2O3S
    N-(4,5-dimethyl-1,3-thiazol-2-yl)-6-ethoxy-2-(4-methoxyphenyl)chromen-4-imine
    —— 2-(6,8-Dichloro-4-oxochromen-2-yl)benzoic acid —— C16H8Cl2O4
    2-(6,8-Dichloro-4-oxochromen-2-yl)benzoic acid
    —— 6-ethoxy-N-(4-ethoxyphenyl)-2-(4-methoxyphenyl)chromen-4-imine —— C26H25NO4
    6-ethoxy-N-(4-ethoxyphenyl)-2-(4-methoxyphenyl)chromen-4-imine
    —— 2-(2-chlorophenyl)-6-methoxy-N-(2-phenylethyl)chromen-4-imine —— C24H20ClNO2
    2-(2-chlorophenyl)-6-methoxy-N-(2-phenylethyl)chromen-4-imine
    —— Ethyl 3-[[6-ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoate —— C27H25NO5
    Ethyl 3-[[6-ethoxy-2-(4-methoxyphenyl)chromen-4-ylidene]amino]benzoate
    —— N-(4-bromophenyl)-2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-imine —— C24H20BrNO4
    N-(4-bromophenyl)-2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-imine
    —— 2-[[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]-N-(furan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide —— C32H30N2O6S
    2-[[2-(3,4-dimethoxyphenyl)-6-methoxychromen-4-ylidene]amino]-N-(furan-2-ylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
    —— 2-(2-chlorophenyl)-6-methoxy-N-(1,3,4-thiadiazol-2-yl)chromen-4-imine —— C18H12ClN3O2S
    2-(2-chlorophenyl)-6-methoxy-N-(1,3,4-thiadiazol-2-yl)chromen-4-imine
    —— 6-ethoxy-2-(4-methoxyphenyl)-N-(4-propan-2-yloxyphenyl)chromen-4-imine —— C27H27NO4
    6-ethoxy-2-(4-methoxyphenyl)-N-(4-propan-2-yloxyphenyl)chromen-4-imine
    —— 2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(4-phenylmethoxyphenyl)chromen-4-imine —— C32H29NO5
    2-(3,4-dimethoxyphenyl)-6-ethoxy-N-(4-phenylmethoxyphenyl)chromen-4-imine
    —— 2-(2-chlorophenyl)-N-(4-fluorophenyl)-6-methoxychromen-4-imine —— C22H15ClFNO2
    2-(2-chlorophenyl)-N-(4-fluorophenyl)-6-methoxychromen-4-imine
    —— 6-ethoxy-N-(2-methoxyethyl)-2-(4-methoxyphenyl)chromen-4-imine —— C21H23NO4
    6-ethoxy-N-(2-methoxyethyl)-2-(4-methoxyphenyl)chromen-4-imine