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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[[2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C26H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C24H19ClN4O3
    N-[[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[(6-methoxy-2-phenylchromen-4-ylidene)amino]quinolin-2-amine —— C25H19N3O2
    N-[(6-methoxy-2-phenylchromen-4-ylidene)amino]quinolin-2-amine
    —— N-[[6,8-dichloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine —— C25H17Cl2N3O2
    N-[[6,8-dichloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C23H17ClN4O2
    N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[6,8-dichloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinolin-1-ium-2-amine —— C26H20Cl2N3O3+
    N-[[6,8-dichloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinolin-1-ium-2-amine
    —— N-[[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C25H22N4O2
    N-[[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine —— C26H20ClN3O3
    N-[[6-chloro-2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[6-chloro-2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-2-amine —— C26H20ClN3O2
    N-[[6-chloro-2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C26H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[2-(4-methoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]quinolin-2-amine —— C27H23N3O2
    N-[[2-(4-methoxyphenyl)-5,7-dimethylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinolin-2-amine —— C27H23N3O2
    N-[[2-(4-methoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinolin-1-ium-2-amine —— C27H24N3O2+
    N-[[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinolin-1-ium-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinolin-2-amine —— C28H25N3O3
    N-[[2-(3,4-dimethoxyphenyl)-6,7-dimethylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]quinolin-2-amine —— C27H23N3O3
    N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C26H24N4O3
    N-[[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[2-(4-methoxyphenyl)-6-methylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C24H20N4O2
    N-[[2-(4-methoxyphenyl)-6-methylchromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— 3-[(3-Chlorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one —— C25H21ClO3
    3-[(3-Chlorophenyl)methoxy]-5,7-dimethyl-2-(4-methylphenyl)chromen-4-one
    —— N-[[6-chloro-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-2-amine —— C27H22ClN3O3
    N-[[6-chloro-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinolin-2-amine —— C27H23N3O2
    N-[[2-(4-methoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinolin-2-amine —— C28H25N3O3
    N-[[2-(3,4-dimethoxyphenyl)-6,8-dimethylchromen-4-ylidene]amino]quinolin-2-amine
    —— 2-(4-Methoxyphenyl)-5,7-dimethyl-3-[4-(4-methylphenoxy)butoxy]chromen-4-one —— C29H30O5
    2-(4-Methoxyphenyl)-5,7-dimethyl-3-[4-(4-methylphenoxy)butoxy]chromen-4-one
    —— N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine —— C25H18ClN3O2
    N-[[6-chloro-2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[6-chloro-2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-1-ium-2-amine —— C26H21ClN3O2+
    N-[[6-chloro-2-(4-methoxyphenyl)-7-methylchromen-4-ylidene]amino]quinolin-1-ium-2-amine
    —— 2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-(2-naphthalen-2-yl-2-oxoethoxy)chromen-4-one —— C31H26O6
    2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-(2-naphthalen-2-yl-2-oxoethoxy)chromen-4-one
    —— 3-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethoxy]-2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-one —— C29H26O8
    3-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethoxy]-2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-one
    —— 3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(4-methoxyphenyl)-5,7-dimethylchromen-4-one —— C25H20ClFO4
    3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(4-methoxyphenyl)-5,7-dimethylchromen-4-one
    —— N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1H-benzimidazol-2-amine —— C23H18N4O2
    N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1H-benzimidazol-2-amine
    —— N-[[2-(4-methoxyphenyl)-6-methylchromen-4-ylidene]amino]quinolin-2-amine —— C26H21N3O2
    N-[[2-(4-methoxyphenyl)-6-methylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine —— C25H19N3O2
    N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine
    —— Methyl 2-[2-[2-(3,4-dimethoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate —— C23H21N3O5S
    Methyl 2-[2-[2-(3,4-dimethoxyphenyl)chromen-4-ylidene]hydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate
    —— N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,3-benzothiazol-2-amine —— C23H17N3O2S
    N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]-1,3-benzothiazol-2-amine
    —— N-(3,5-dichlorophenyl)-2-[2-(4-methoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetamide —— C26H21Cl2NO5
    N-(3,5-dichlorophenyl)-2-[2-(4-methoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxyacetamide
    —— 3-[(2-Fluorophenyl)methoxy]-2-(4-methoxyphenyl)-5,7-dimethylchromen-4-one —— C25H21FO4
    3-[(2-Fluorophenyl)methoxy]-2-(4-methoxyphenyl)-5,7-dimethylchromen-4-one
    —— N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine —— C24H18N4O2
    N-[[2-(4-methoxyphenyl)chromen-4-ylidene]amino]quinazolin-4-amine
    —— 2-(4-Methoxyphenyl)-5,7-dimethyl-3-[2-oxo-2-(4-propan-2-ylphenyl)ethoxy]chromen-4-one —— C29H28O5
    2-(4-Methoxyphenyl)-5,7-dimethyl-3-[2-oxo-2-(4-propan-2-ylphenyl)ethoxy]chromen-4-one
    —— N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]quinolin-2-amine —— C28H25N3O3
    N-[[2-(3,4-dimethoxyphenyl)-6-ethylchromen-4-ylidene]amino]quinolin-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]-1,3-benzothiazol-2-amine —— C24H19N3O3S
    N-[[2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]-1,3-benzothiazol-2-amine
    —— N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]quinolin-1-ium-2-amine —— C27H24N3O3+
    N-[[2-(3,4-dimethoxyphenyl)-6-methylchromen-4-ylidene]amino]quinolin-1-ium-2-amine
    —— 2-(2-Chlorophenyl)-6,8-dimethyl-3-(2-phenoxyethoxy)chromen-4-one —— C25H21ClO4
    2-(2-Chlorophenyl)-6,8-dimethyl-3-(2-phenoxyethoxy)chromen-4-one
    —— [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate —— C29H22O8
    [2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate
    —— N-[[2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine —— C26H21N3O3
    N-[[2-(3,4-dimethoxyphenyl)chromen-4-ylidene]amino]quinolin-2-amine
    —— 5,7-Dimethyl-2-(4-methylphenyl)-3-(naphthalen-1-ylmethoxy)chromen-4-one —— C29H24O3
    5,7-Dimethyl-2-(4-methylphenyl)-3-(naphthalen-1-ylmethoxy)chromen-4-one
    —— 2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-[3-(4-methylphenoxy)propoxy]chromen-4-one —— C29H30O6
    2-(3,4-Dimethoxyphenyl)-5,7-dimethyl-3-[3-(4-methylphenoxy)propoxy]chromen-4-one
    —— 2-[2-(4-methoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide —— C27H22F3NO5
    2-[2-(4-methoxyphenyl)-5,7-dimethyl-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide
    —— 2-(4-Methoxyphenyl)-5,7-dimethyl-3-(3-phenoxypropoxy)chromen-4-one —— C27H26O5
    2-(4-Methoxyphenyl)-5,7-dimethyl-3-(3-phenoxypropoxy)chromen-4-one
    —— 3-[(3-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-one —— C26H23ClO5
    3-[(3-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-5,7-dimethylchromen-4-one
    —— 5,7-Dimethyl-2-(4-methylphenyl)-3-(3-phenoxypropoxy)chromen-4-one —— C27H26O4
    5,7-Dimethyl-2-(4-methylphenyl)-3-(3-phenoxypropoxy)chromen-4-one
    —— 2-(4-Methoxyphenyl)-5,7-dimethyl-3-[(3-methylphenyl)methoxy]chromen-4-one —— C26H24O4
    2-(4-Methoxyphenyl)-5,7-dimethyl-3-[(3-methylphenyl)methoxy]chromen-4-one
    —— 2-(3,4-dimethoxyphenyl)-5,7-dimethyl-3-[(2S)-1-oxo-1-phenylpropan-2-yl]oxychromen-4-one —— C28H26O6
    2-(3,4-dimethoxyphenyl)-5,7-dimethyl-3-[(2S)-1-oxo-1-phenylpropan-2-yl]oxychromen-4-one