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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— Propan-2-yl 4-[[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxymethyl]benzoate —— C29H28O7
    Propan-2-yl 4-[[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxymethyl]benzoate
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 3,4,5-trimethoxybenzoate —— C28H26O9
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 3,4,5-trimethoxybenzoate
    —— 2-Phenylethyl 2-[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C28H26O7
    2-Phenylethyl 2-[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
    —— 2-(3,4-Dimethoxyphenyl)-7-methyl-3-(naphthalen-1-ylmethoxy)chromen-4-one —— C29H24O5
    2-(3,4-Dimethoxyphenyl)-7-methyl-3-(naphthalen-1-ylmethoxy)chromen-4-one
    —— 3-[(3-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one —— C25H21ClO5
    3-[(3-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one
    —— 2-(3,4-Dimethoxyphenyl)-7-methyl-3-propan-2-yloxychromen-4-one —— C21H22O5
    2-(3,4-Dimethoxyphenyl)-7-methyl-3-propan-2-yloxychromen-4-one
    —— 3-[(2-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one —— C25H21ClO5
    3-[(2-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] benzoate —— C25H20O6
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] benzoate
    —— 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(2,4,6-trimethylphenyl)acetamide —— C28H27NO5
    2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(2,4,6-trimethylphenyl)acetamide
    —— (2S)-2-[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid —— C21H20O7
    (2S)-2-[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid
    —— 2-(3,4-Dimethoxyphenyl)-7-methyl-3-[(3-methylphenyl)methoxy]chromen-4-one —— C26H24O5
    2-(3,4-Dimethoxyphenyl)-7-methyl-3-[(3-methylphenyl)methoxy]chromen-4-one
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] furan-2-carboxylate —— C23H18O7
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] furan-2-carboxylate
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] benzenesulfonate —— C24H20O7S
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] benzenesulfonate
    —— 2-(3,4-Dimethoxyphenyl)-3-[2-(4-methoxyphenyl)-2-oxoethoxy]-7-methylchromen-4-one —— C27H24O7
    2-(3,4-Dimethoxyphenyl)-3-[2-(4-methoxyphenyl)-2-oxoethoxy]-7-methylchromen-4-one
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] pyridine-3-carboxylate —— C24H19NO6
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] pyridine-3-carboxylate
    —— 3-[2-(4-Ethoxyphenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C27H24O6
    3-[2-(4-Ethoxyphenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one
    —— 2-[2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C20H19NO6
    2-[2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— 3-[(2,4-Dichlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one —— C25H20Cl2O5
    3-[(2,4-Dichlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one
    —— 2-[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(2-phenylethyl)acetamide —— C28H27NO6
    2-[2-(3,4-dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(2-phenylethyl)acetamide
    —— 3-[2-(2,4-Dichlorophenyl)-2-oxoethoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one —— C26H20Cl2O6
    3-[2-(2,4-Dichlorophenyl)-2-oxoethoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one
    —— Ethyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C21H20O6
    Ethyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
    —— 3-[2-(2,4-Dichlorophenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C25H18Cl2O5
    3-[2-(2,4-Dichlorophenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one
    —— N-(4-fluorophenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C25H20FNO5
    N-(4-fluorophenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— 3-[(3,4-Dichlorophenyl)methoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C24H18Cl2O4
    3-[(3,4-Dichlorophenyl)methoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one
    —— 2-(4-Methoxyphenyl)-7-methyl-3-(2-oxopropoxy)chromen-4-one —— C20H18O5
    2-(4-Methoxyphenyl)-7-methyl-3-(2-oxopropoxy)chromen-4-one
    —— N-(2-chlorophenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C25H20ClNO5
    N-(2-chlorophenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— 3-Phenylpropyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C28H26O6
    3-Phenylpropyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 2,2-dimethylpropanoate —— C23H24O6
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 2,2-dimethylpropanoate
    —— 2-(4-Methoxyphenyl)-7-methyl-3-(2-oxo-2-thiophen-2-ylethoxy)chromen-4-one —— C23H18O5S
    2-(4-Methoxyphenyl)-7-methyl-3-(2-oxo-2-thiophen-2-ylethoxy)chromen-4-one
    —— N-(furan-2-ylmethyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C24H21NO6
    N-(furan-2-ylmethyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— 3-[(2,6-Dichlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one —— C25H20Cl2O5
    3-[(2,6-Dichlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)-7-methylchromen-4-one
    —— 2-[2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C20H17O7-
    2-[2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
    —— N-(2,3-dimethylphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C27H25NO5
    N-(2,3-dimethylphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(1,3-thiazol-2-yl)acetamide —— C22H18N2O5S
    2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxy-N-(1,3-thiazol-2-yl)acetamide
    —— 2-(3,4-Dimethoxyphenyl)-7-methyl-3-[(4-methylphenyl)methoxy]chromen-4-one —— C26H24O5
    2-(3,4-Dimethoxyphenyl)-7-methyl-3-[(4-methylphenyl)methoxy]chromen-4-one
    —— 2-Ethoxyethyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C23H24O7
    2-Ethoxyethyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
    —— [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate —— C28H20O8
    [2-(3,4-Dimethoxyphenyl)-7-methyl-4-oxochromen-3-yl] 2-oxochromene-3-carboxylate
    —— N-(4-ethoxyphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C27H25NO6
    N-(4-ethoxyphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— N-(4-butylphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C29H29NO5
    N-(4-butylphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— ethyl (2R)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate —— C22H22O6
    ethyl (2R)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoate
    —— 3-[2-(4-Chlorophenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C25H19ClO5
    3-[2-(4-Chlorophenyl)-2-oxoethoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one
    —— (2R)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid —— C20H18O6
    (2R)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxypropanoic acid
    —— 2-(4-Methoxyphenyl)-7-methyl-3-(2-propan-2-yloxyethoxy)chromen-4-one —— C22H24O5
    2-(4-Methoxyphenyl)-7-methyl-3-(2-propan-2-yloxyethoxy)chromen-4-one
    —— N-(4-chlorophenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C25H20ClNO5
    N-(4-chlorophenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— N-(2-ethoxyphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide —— C27H25NO6
    N-(2-ethoxyphenyl)-2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetamide
    —— 2-[2-(4-Methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetic acid —— C19H16O6
    2-[2-(4-Methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetic acid
    —— 3-[(2,4-Dichlorophenyl)methoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C24H18Cl2O4
    3-[(2,4-Dichlorophenyl)methoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one
    —— 3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one —— C24H18ClFO4
    3-[(2-Chloro-6-fluorophenyl)methoxy]-2-(4-methoxyphenyl)-7-methylchromen-4-one
    —— Benzyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate —— C26H22O6
    Benzyl 2-[2-(4-methoxyphenyl)-7-methyl-4-oxochromen-3-yl]oxyacetate
    —— 2-(4-Methoxyphenyl)-7-methyl-3-[2-oxo-2-(4-phenylphenyl)ethoxy]chromen-4-one —— C31H24O5
    2-(4-Methoxyphenyl)-7-methyl-3-[2-oxo-2-(4-phenylphenyl)ethoxy]chromen-4-one