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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 黄酮类化合物

    黄酮类化合物

    黄酮类化合物 定义与结构特征

    黄酮类化合物是一大类天然存在的有机化合物，属于酚类衍生物。它们的分子结构通常包含两个苯环（A和B环）和一个三碳环（C环），形成一个基本骨架。该骨架由多个亚结构组成，包括黄烷醇、黄酮、黄酮醇等。

    生物来源

    黄酮类化合物广泛存在于植物界中，常见于许多蔬菜、水果及中药中。例如，在大豆、柑橘、茶叶和甘草中都可以找到它们的身影。

    化学性质 亲水性与溶解度

    由于其分子结构中含有多个酚羟基，因此具有一定的亲水性和良好的溶解性，这使得黄酮类化合物在药物设计中扮演重要角色。

    稳定性与光敏性

    大多数黄酮类化合物相对稳定，在适宜条件下不易发生降解。但某些类型的黄酮对光照比较敏感，容易被氧化，导致颜色变化。

    生理活性与药用价值

    黄酮类化合物因其丰富的生理活性而备受关注，主要包括：

    • 抗氧化作用：可有效清除体内自由基，保护细胞免受损伤。
    • 抗炎效应：有助于减轻炎症反应，缓解症状。
    • 心血管保护：可能通过多种机制改善心脑血管健康。
    • 抗癌潜力：研究表明某些黄酮类物质具有抑制肿瘤生长的能力。
    应用领域 食品工业

    作为一种天然色素和抗氧化剂，被广泛应用于食品加工中以提高其保质期及营养价值。

    化妆品行业

    利用其良好的生物相容性和抗衰老特性，在化妆品配方中应用广泛。

    药物开发

    由于黄酮类化合物展现出广泛的药理活性，已成为新药研发的重要候选目标之一。

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxy-N-(2-fluorophenyl)acetamide —— C25H20FNO6
    2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxy-N-(2-fluorophenyl)acetamide
    —— [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] 2-(1,3-dioxoisoindol-2-yl)acetate —— C25H13Cl2NO6
    [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] 2-(1,3-dioxoisoindol-2-yl)acetate
    —— [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] pyridine-3-carboxylate —— C21H11Cl2NO4
    [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] pyridine-3-carboxylate
    —— N-(4-bromophenyl)-2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetamide —— C25H20BrNO6
    N-(4-bromophenyl)-2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetamide
    —— N-(furan-2-ylmethyl)-2-(4-oxo-2-phenylchromen-3-yl)oxyacetamide —— C22H17NO5
    N-(furan-2-ylmethyl)-2-(4-oxo-2-phenylchromen-3-yl)oxyacetamide
    —— [2-(3-Bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl] 2,2-dimethylpropanoate —— C22H21BrO6
    [2-(3-Bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl] 2,2-dimethylpropanoate
    —— 2-[2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(2-propan-2-ylphenyl)acetamide —— C27H25NO4
    2-[2-(4-methylphenyl)-4-oxochromen-3-yl]oxy-N-(2-propan-2-ylphenyl)acetamide
    —— 2-(3-Bromo-4,5-dimethoxyphenyl)-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one —— C26H23BrO6
    2-(3-Bromo-4,5-dimethoxyphenyl)-3-[2-(4-methylphenoxy)ethoxy]chromen-4-one
    —— N-(2,4-dimethoxyphenyl)-2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetamide —— C27H25NO8
    N-(2,4-dimethoxyphenyl)-2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetamide
    —— 2-[2-(4-tert-butylphenyl)-4-oxochromen-3-yl]oxy-N-(4-chloro-2-methylphenyl)acetamide —— C28H26ClNO4
    2-[2-(4-tert-butylphenyl)-4-oxochromen-3-yl]oxy-N-(4-chloro-2-methylphenyl)acetamide
    —— [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] 4-chlorobenzoate —— C22H11Cl3O4
    [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] 4-chlorobenzoate
    —— Ethyl 4-[[2-[2-(4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetyl]amino]benzoate —— C27H23NO7
    Ethyl 4-[[2-[2-(4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetyl]amino]benzoate
    —— [2-(3-bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl] (E)-3-(3,4-dimethoxyphenyl)prop-2-enoate —— C28H23BrO8
    [2-(3-bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl] (E)-3-(3,4-dimethoxyphenyl)prop-2-enoate
    —— 2-[2-(3,4-Dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetic acid —— C19H16O7
    2-[2-(3,4-Dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetic acid
    —— [2-(2,4-dichlorophenyl)-4-oxochromen-3-yl] (E)-3-(4-chlorophenyl)prop-2-enoate —— C24H13Cl3O4
    [2-(2,4-dichlorophenyl)-4-oxochromen-3-yl] (E)-3-(4-chlorophenyl)prop-2-enoate
    —— N-(3,4-dimethylphenyl)-2-[2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetamide —— C26H23NO4
    N-(3,4-dimethylphenyl)-2-[2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetamide
    —— 2-[2-(4-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2-methylphenyl)acetamide —— C24H18ClNO4
    2-[2-(4-chlorophenyl)-4-oxochromen-3-yl]oxy-N-(2-methylphenyl)acetamide
    —— Benzyl 2-[2-(4-chlorophenyl)-4-oxochromen-3-yl]oxyacetate —— C24H17ClO5
    Benzyl 2-[2-(4-chlorophenyl)-4-oxochromen-3-yl]oxyacetate
    —— 2-(4-oxo-2-phenylchromen-3-yl)oxy-N-[3-(trifluoromethyl)phenyl]acetamide —— C24H16F3NO4
    2-(4-oxo-2-phenylchromen-3-yl)oxy-N-[3-(trifluoromethyl)phenyl]acetamide
    —— N-(2,4-dimethoxyphenyl)-2-(4-oxo-2-phenylchromen-3-yl)oxyacetamide —— C25H21NO6
    N-(2,4-dimethoxyphenyl)-2-(4-oxo-2-phenylchromen-3-yl)oxyacetamide
    —— Ethyl 2-[2-(3-bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate —— C21H19BrO7
    Ethyl 2-[2-(3-bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate
    —— [2-(3-Bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl] 3-phenylpropanoate —— C26H21BrO6
    [2-(3-Bromo-4,5-dimethoxyphenyl)-4-oxochromen-3-yl] 3-phenylpropanoate
    —— N-(3,4-dichlorophenyl)-2-[2-(4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetamide —— C24H17Cl2NO5
    N-(3,4-dichlorophenyl)-2-[2-(4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetamide
    —— Methyl 2-[[2-[2-(4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetyl]amino]benzoate —— C26H21NO7
    Methyl 2-[[2-[2-(4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetyl]amino]benzoate
    —— 2-[2-(2,4-dichlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-ethoxyphenyl)acetamide —— C25H19Cl2NO5
    2-[2-(2,4-dichlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-ethoxyphenyl)acetamide
    —— [2-(3-Bromo-4-methoxyphenyl)-4-oxochromen-3-yl] 4-(1,3-dioxoisoindol-2-yl)butanoate —— C28H20BrNO7
    [2-(3-Bromo-4-methoxyphenyl)-4-oxochromen-3-yl] 4-(1,3-dioxoisoindol-2-yl)butanoate
    —— [2-(4-tert-butylphenyl)-4-oxochromen-3-yl] (E)-3-phenylprop-2-enoate —— C28H24O4
    [2-(4-tert-butylphenyl)-4-oxochromen-3-yl] (E)-3-phenylprop-2-enoate
    —— Benzyl 2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate —— C26H22O7
    Benzyl 2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate
    —— Ethyl 4-[[2-[2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetyl]amino]benzoate —— C27H23NO6
    Ethyl 4-[[2-[2-(4-methylphenyl)-4-oxochromen-3-yl]oxyacetyl]amino]benzoate
    —— 2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide —— C24H24BrNO5
    2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxy-N-cyclohexylacetamide
    —— 2-Methoxyethyl 2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetate —— C21H19BrO7
    2-Methoxyethyl 2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxyacetate
    —— 3-[(3-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)chromen-4-one —— C24H19ClO5
    3-[(3-Chlorophenyl)methoxy]-2-(3,4-dimethoxyphenyl)chromen-4-one
    —— Methyl 4-[[2-(2-chlorophenyl)-4-oxochromen-3-yl]oxymethyl]benzoate —— C24H17ClO5
    Methyl 4-[[2-(2-chlorophenyl)-4-oxochromen-3-yl]oxymethyl]benzoate
    —— [2-(4-Tert-butylphenyl)-4-oxochromen-3-yl] 3-methylbut-2-enoate —— C24H24O4
    [2-(4-Tert-butylphenyl)-4-oxochromen-3-yl] 3-methylbut-2-enoate
    —— N-(4-bromophenyl)-2-[2-(4-chlorophenyl)-4-oxochromen-3-yl]oxyacetamide —— C23H15BrClNO4
    N-(4-bromophenyl)-2-[2-(4-chlorophenyl)-4-oxochromen-3-yl]oxyacetamide
    —— [2-(4-Tert-butylphenyl)-4-oxochromen-3-yl] 2,2-dimethylpropanoate —— C24H26O4
    [2-(4-Tert-butylphenyl)-4-oxochromen-3-yl] 2,2-dimethylpropanoate
    —— [2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl] (E)-3-(2-chlorophenyl)prop-2-enoate —— C25H16BrClO5
    [2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl] (E)-3-(2-chlorophenyl)prop-2-enoate
    —— 2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxy-N-(3,5-dichlorophenyl)acetamide —— C24H16BrCl2NO5
    2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxy-N-(3,5-dichlorophenyl)acetamide
    —— 2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide —— C25H17BrF3NO5
    2-[2-(3-bromo-4-methoxyphenyl)-4-oxochromen-3-yl]oxy-N-[2-(trifluoromethyl)phenyl]acetamide
    —— 2-[2-(4-tert-butylphenyl)-4-oxochromen-3-yl]oxy-N-(3-chlorophenyl)acetamide —— C27H24ClNO4
    2-[2-(4-tert-butylphenyl)-4-oxochromen-3-yl]oxy-N-(3-chlorophenyl)acetamide
    —— 2-(4-Tert-butylphenyl)-3-[(3-chlorophenyl)methoxy]chromen-4-one —— C26H23ClO3
    2-(4-Tert-butylphenyl)-3-[(3-chlorophenyl)methoxy]chromen-4-one
    —— 2-[2-(2,4-dichlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide —— C23H14Cl2FNO4
    2-[2-(2,4-dichlorophenyl)-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide
    —— [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] 4-nitrobenzoate —— C22H11Cl2NO6
    [2-(2,4-Dichlorophenyl)-4-oxochromen-3-yl] 4-nitrobenzoate
    —— N-(3-chloro-4-methoxyphenyl)-2-(4-oxo-2-phenylchromen-3-yl)oxyacetamide —— C24H18ClNO5
    N-(3-chloro-4-methoxyphenyl)-2-(4-oxo-2-phenylchromen-3-yl)oxyacetamide
    —— 2-[2-(4-tert-butylphenyl)-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide —— C27H24FNO4
    2-[2-(4-tert-butylphenyl)-4-oxochromen-3-yl]oxy-N-(4-fluorophenyl)acetamide
    —— [2-(3-Bromo-4-methoxyphenyl)-4-oxochromen-3-yl] 3-chlorobenzoate —— C23H14BrClO5
    [2-(3-Bromo-4-methoxyphenyl)-4-oxochromen-3-yl] 3-chlorobenzoate
    —— Methyl 2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate —— C20H18O7
    Methyl 2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate
    —— 2-(4-Tert-butylphenyl)-3-(naphthalen-1-ylmethoxy)chromen-4-one —— C30H26O3
    2-(4-Tert-butylphenyl)-3-(naphthalen-1-ylmethoxy)chromen-4-one
    —— N-(4-fluorophenyl)-2-(4-oxo-2-phenyl-4H-chromen-3-yloxy)acetamide 819832-54-7 C23H16FNO4
    N-(4-fluorophenyl)-2-(4-oxo-2-phenyl-4H-chromen-3-yloxy)acetamide
    —— 2-Methoxyethyl 2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate —— C22H22O8
    2-Methoxyethyl 2-[2-(3,4-dimethoxyphenyl)-4-oxochromen-3-yl]oxyacetate