摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-(((4-Fluorophenyl)thio)methyl)pyrrolidine hydrochloride 1353989-69-1 C11H15ClFNS
    2-(((4-Fluorophenyl)thio)methyl)pyrrolidine hydrochloride
    —— 6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-nitrophenyl)-1,3,5-triazine-2,4-diamine 1408322-25-7 C28H24N12O4S2
    6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-nitrophenyl)-1,3,5-triazine-2,4-diamine
    —— 1-(6-Methoxy-2-(methylthio)pyrimidin-4-yl)piperidin-4-ol 1353979-87-9 C11H17N3O2S
    1-(6-Methoxy-2-(methylthio)pyrimidin-4-yl)piperidin-4-ol
    —— 1-(6-Ethoxy-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol 1353954-83-2 C12H19N3O2S
    1-(6-Ethoxy-2-(methylthio)pyrimidin-4-yl)piperidin-3-ol
    —— 2-(((4-Chlorophenyl)thio)methyl)pyrrolidine hydrochloride 1353945-59-1 C11H15Cl2NS
    2-(((4-Chlorophenyl)thio)methyl)pyrrolidine hydrochloride
    —— (R)-1-(6-Ethoxy-2-(methylthio)pyrimidin-4-yl)pyrrolidin-3-ol 1354019-51-4 C11H17N3O2S
    (R)-1-(6-Ethoxy-2-(methylthio)pyrimidin-4-yl)pyrrolidin-3-ol
    —— 6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-fluorophenyl)-1,3,5-triazine-2,4-diamine 1408322-22-4 C28H24F2N10S2
    6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-fluorophenyl)-1,3,5-triazine-2,4-diamine
    —— 6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-methoxyphenyl)-1,3,5-triazine-2,4-diamine 1408322-24-6 C30H30N10O2S2
    6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-methoxyphenyl)-1,3,5-triazine-2,4-diamine
    —— [1-<sup>14</sup>C]-(R)-2-(2-amino-5-((S)-1-phenylethylthio)thiazolo[4,5-d]pyrimidin-7-ylamino)-4-methylpentan-1-ol 1403762-04-8 C19H25N5OS2
    [1-<sup>14</sup>C]-(R)-2-(2-amino-5-((S)-1-phenylethylthio)thiazolo[4,5-d]pyrimidin-7-ylamino)-4-methylpentan-1-ol
    —— 2-N,4-N-bis(4-bromophenyl)-6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-1,3,5-triazine-2,4-diamine 1408322-21-3 C28H24Br2N10S2
    2-N,4-N-bis(4-bromophenyl)-6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-1,3,5-triazine-2,4-diamine
    —— 6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-methylphenyl)-1,3,5-triazine-2,4-diamine 1408322-23-5 C30H30N10S2
    6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-2-N,4-N-bis(4-methylphenyl)-1,3,5-triazine-2,4-diamine
    —— 2-N,4-N-bis(4-chlorophenyl)-6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-1,3,5-triazine-2,4-diamine 1408322-20-2 C28H24Cl2N10S2
    2-N,4-N-bis(4-chlorophenyl)-6-[[5-[(3,5-dimethyl-2-phenyl-3,4-dihydropyrazol-4-yl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]-1,3,5-triazine-2,4-diamine
    —— 4-[3-({4-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-fluorophenyl}thio)phenyl]tetrahydro-2H-pyran-4-carboxamide 1159186-46-5 C23H25FN2O3S
    4-[3-({4-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-fluorophenyl}thio)phenyl]tetrahydro-2H-pyran-4-carboxamide
    —— (4-chloro-3-trifluoromethylsulfanyl-phenyl)-piperidin-4-yl-amine hydrochloride 1247029-13-5 C12H14ClF3N2S*ClH
    (4-chloro-3-trifluoromethylsulfanyl-phenyl)-piperidin-4-yl-amine hydrochloride
    —— (4-bromo-2-fluoro-5-methylphenyl)(methyl)sulfane 1011460-51-7 C8H8BrFS
    (4-bromo-2-fluoro-5-methylphenyl)(methyl)sulfane
    —— 4-[(4-hydroxyphenyl)thio]-N-methyl-N-[2-(1,2,3,6-tetrahydropyridin-4-yl)benzyl]butanamide 1229040-96-3 C23H28N2O2S
    4-[(4-hydroxyphenyl)thio]-N-methyl-N-[2-(1,2,3,6-tetrahydropyridin-4-yl)benzyl]butanamide
    —— N-(2-bromobenzyl)-4-[(4-hydroxyphenyl)thio]-N-methylbutanamide 1229041-26-2 C18H20BrNO2S
    N-(2-bromobenzyl)-4-[(4-hydroxyphenyl)thio]-N-methylbutanamide
    —— 4-[(4-hydroxyphenyl)thio]-N-methyl-N-[2-(N'-boc-1,2,3,6-tetrahydropyridin-4-yl)benzyl]butanamide 1229041-27-3 C28H36N2O4S
    4-[(4-hydroxyphenyl)thio]-N-methyl-N-[2-(N'-boc-1,2,3,6-tetrahydropyridin-4-yl)benzyl]butanamide
    —— α-Chlordicyclopropylsulfon 27531-50-6 C6H9ClO2S
    α-Chlordicyclopropylsulfon
    —— N-{6-{[(1R)-2-hydroxy-1-methylethyl]amino}-2-[(2,3,4-trifluorobenzyl)thio]pyrimidin-4-yl}-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide 654073-39-9 C23H34F3N5O4S2Si
    N-{6-{[(1R)-2-hydroxy-1-methylethyl]amino}-2-[(2,3,4-trifluorobenzyl)thio]pyrimidin-4-yl}-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide
    —— Tert-butyl cyclobutyl sulfone 713109-35-4 C8H16O2S
    Tert-butyl cyclobutyl sulfone
    —— N-(2-[benzylthio]-6-{[(1R)-2-hydroxy-1-methylethyl]amino}-pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}morpholine-4-sulfonamide 654074-11-0 C24H39N5O5S2Si
    N-(2-[benzylthio]-6-{[(1R)-2-hydroxy-1-methylethyl]amino}-pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}morpholine-4-sulfonamide
    —— N-(2-[(3-chloro-2-fluorobenzyl)thio]-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide 654073-37-7 C23H35ClFN5O4S2Si
    N-(2-[(3-chloro-2-fluorobenzyl)thio]-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide
    —— N-(2-(benzylthio)-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide 654073-34-4 C23H37N5O4S2Si
    N-(2-(benzylthio)-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide
    —— N-(2-[(2,3-difluoro-4-methylbenzyl)thio]-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide 654073-41-3 C24H37F2N5O4S2Si
    N-(2-[(2,3-difluoro-4-methylbenzyl)thio]-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}azetidine-1-sulfonamide
    —— N-(2-(benzylthio)-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}pyrrolidine-1-sulfonamide 654074-20-1 C24H39N5O4S2Si
    N-(2-(benzylthio)-6-{[(1R)-2-hydroxy-1-methylethyl]amino}pyrimidin-4-yl)-N-{[2-(trimethylsilyl)ethoxy]methyl}pyrrolidine-1-sulfonamide
    —— 2-amino-2-{2-[4-(5-phenylthionaphthalen-1-yl)phenyl]ethyl}propane-1,3-diol hydrochloride 956036-85-4 C27H27NO2S*ClH
    2-amino-2-{2-[4-(5-phenylthionaphthalen-1-yl)phenyl]ethyl}propane-1,3-diol hydrochloride
    —— 2-(Hydroxyethyl) phenyl sulfide 129524-69-2 C16H18O2S
    2-(Hydroxyethyl) phenyl sulfide
    —— 2-amino-2-(2-{4-[5-(4-methylphenylthio)naphthalen-1-yl]phenyl}ethyl)propane-1,3-diol hydrochloride 956036-86-5 C28H29NO2S*ClH
    2-amino-2-(2-{4-[5-(4-methylphenylthio)naphthalen-1-yl]phenyl}ethyl)propane-1,3-diol hydrochloride
    —— 3-(2-methylthio-6-trifluoromethylpyrimidin-4-yl)-1,2,4-oxadiazol-5-one 1256638-11-5 C8H5F3N4O2S
    3-(2-methylthio-6-trifluoromethylpyrimidin-4-yl)-1,2,4-oxadiazol-5-one
    —— 3-{6-chloro-2-methyl-1-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-1H-indol-3-ylsulfanyl}-benzoic acid ethyl ester 1359981-11-5 C23H19ClF3N3O2S
    3-{6-chloro-2-methyl-1-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-1H-indol-3-ylsulfanyl}-benzoic acid ethyl ester
    —— 3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzonitrile 1359982-10-7 C23H17ClN2S
    3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzonitrile
    —— 3-(6-chloro-1-isothiazol-4-yl-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester 1359980-66-7 C21H17ClN2O2S2
    3-(6-chloro-1-isothiazol-4-yl-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester
    —— [3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-methanol 1359980-05-4 C23H20ClNOS
    [3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-methanol
    —— 3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester 1359979-94-4 C24H20ClNO2S
    3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester
    —— [3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetonitrile 1359982-07-2 C24H19ClN2S
    [3-(1-benzyl-6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetonitrile
    —— 2-({4-[(3-chloro-2-methylphenyl)methyl]-2-(morpholin-4-yl)-7-oxo-4H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)acetic acid 1256290-18-2 C19H19ClN4O4S2
    2-({4-[(3-chloro-2-methylphenyl)methyl]-2-(morpholin-4-yl)-7-oxo-4H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)acetic acid
    —— 3-[3-[7-(1-hydroxy-1-methyl-ethyl)-pyrido[2,3-d]pyrimidin-4-ylamino]-4-(4-hydroxy-phenylsulfanyl)-phenoxymethyl]-benzonitrile 944502-63-0 C30H25N5O3S
    3-[3-[7-(1-hydroxy-1-methyl-ethyl)-pyrido[2,3-d]pyrimidin-4-ylamino]-4-(4-hydroxy-phenylsulfanyl)-phenoxymethyl]-benzonitrile
    —— 6-{[(1R,3S,4S)-3-{[tert-butyl(dimethyl)silyl]oxy}-4-({[tert-butyl(dimethyl)silyl]oxy}-methyl)cyclopentyl]oxy}-8-[(3-methylphenyl)sulfanyl]-9H-purine 1007126-15-9 C30H48N4O3SSi2
    6-{[(1R,3S,4S)-3-{[tert-butyl(dimethyl)silyl]oxy}-4-({[tert-butyl(dimethyl)silyl]oxy}-methyl)cyclopentyl]oxy}-8-[(3-methylphenyl)sulfanyl]-9H-purine
    —— 4-[2-amino-4-(2,5-difluoro-benzyloxy)-phenylsulfanyl]-phenol 944506-29-0 C19H15F2NO2S
    4-[2-amino-4-(2,5-difluoro-benzyloxy)-phenylsulfanyl]-phenol
    —— 4-[2-amino-4-(3-fluoro-benzyloxy)-phenylsulfanyl]-phenol 943771-52-6 C19H16FNO2S
    4-[2-amino-4-(3-fluoro-benzyloxy)-phenylsulfanyl]-phenol
    —— 4-{2-amino-4-[1-(3-bromo-phenyl)-ethoxy]-phenylsulfanyl}-phenol 943774-66-1 C20H18BrNO2S
    4-{2-amino-4-[1-(3-bromo-phenyl)-ethoxy]-phenylsulfanyl}-phenol
    —— 4-[2-amino-4-(3-bromo-benzyloxy)-phenylsulfanyl]-phenol 1076223-03-4 C19H16BrNO2S
    4-[2-amino-4-(3-bromo-benzyloxy)-phenylsulfanyl]-phenol
    —— 4-[2-amino-4-(3-trifluoromethylbenzyloxy)-phenylsulfanyl]-phenol 1076223-02-3 C20H16F3NO2S
    4-[2-amino-4-(3-trifluoromethylbenzyloxy)-phenylsulfanyl]-phenol
    —— 2-{[(5-amino-2-chlorophenyl)methyl]sulfanyl}-6-methylpyrimidin-4-ol hydrochloride 1256557-51-3 C12H12ClN3OS*ClH
    2-{[(5-amino-2-chlorophenyl)methyl]sulfanyl}-6-methylpyrimidin-4-ol hydrochloride
    —— 2-{[(4-chloro-2-ethylpyridin-3-yl)methyl]sulfanyl}-6-(trifluoromethyl)pyrimidin-4-ol hydrochloride 1256558-70-9 C13H11ClF3N3OS*ClH
    2-{[(4-chloro-2-ethylpyridin-3-yl)methyl]sulfanyl}-6-(trifluoromethyl)pyrimidin-4-ol hydrochloride
    —— 2-{[(2,4-diethylpyridin-3-yl)methyl]sulfanyl}-6-(trifluoromethyl)pyrimidin-4-ol hydrochloride 1256558-72-1 C15H16F3N3OS*ClH
    2-{[(2,4-diethylpyridin-3-yl)methyl]sulfanyl}-6-(trifluoromethyl)pyrimidin-4-ol hydrochloride
    —— 2-(1,2,3-Thiadiazol-5-ylthio)acetic acid 75849-84-2 C4H4N2O2S2
    2-(1,2,3-Thiadiazol-5-ylthio)acetic acid
    —— 2-{[(4-chloro-1-methyl-1H-pyrazol-3-yl)methyl]sulfanyl}-6-(trifluoromethyl)pyrimidin-4-ol hydrochloride 1256558-67-4 C10H8ClF3N4OS*ClH
    2-{[(4-chloro-1-methyl-1H-pyrazol-3-yl)methyl]sulfanyl}-6-(trifluoromethyl)pyrimidin-4-ol hydrochloride
    —— 1,1-dioxo-3-methyl-3-thietanamine trifluoroacetate 943438-03-7 C2HF3O2*C4H9NO2S
    1,1-dioxo-3-methyl-3-thietanamine trifluoroacetate