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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2,2-dimethyl-5-(1-(2-(methylthio)phenyl)cyclohexyl)-1,3-dioxane-4,6-dione 1098073-28-9 C19H24O4S
    2,2-dimethyl-5-(1-(2-(methylthio)phenyl)cyclohexyl)-1,3-dioxane-4,6-dione
    —— 2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole 178979-32-3 C15H18ClN3O2S
    2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole
    —— 2-(5-amino-2-chloro-4-fluorophenylthio)-4-bromobutyric acid methyl ester 140909-44-0 C11H12BrClFNO2S
    2-(5-amino-2-chloro-4-fluorophenylthio)-4-bromobutyric acid methyl ester
    —— 2-[N'-(6-Chloro-7-methyl-1,1-dioxo-1H-1λ<sup>6</sup>-benzo[1,4,2]dithiazin-3-yl)-hydrazino]-ethanol 227177-51-7 C10H12ClN3O3S2
    2-[N'-(6-Chloro-7-methyl-1,1-dioxo-1H-1λ<sup>6</sup>-benzo[1,4,2]dithiazin-3-yl)-hydrazino]-ethanol
    —— 4(1H)-Pyrimidinone, 2-((2-methoxyphenyl)thio)-6-(1-methylpropoxy)- 284681-74-9 C15H18N2O3S
    4(1H)-Pyrimidinone, 2-((2-methoxyphenyl)thio)-6-(1-methylpropoxy)-
    —— 2(1H)-Pyridinone, 5-((5-((3,5-dichlorophenyl)thio)-2-(hydroxymethyl)-4-(1-methylethyl)-1H-imidazol-1-yl)methyl)- 178980-50-2 C19H19Cl2N3O2S
    2(1H)-Pyridinone, 5-((5-((3,5-dichlorophenyl)thio)-2-(hydroxymethyl)-4-(1-methylethyl)-1H-imidazol-1-yl)methyl)-
    —— 1-Benzyl-2-carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1H-imidazole 178979-36-7 C21H22ClN3O2S
    1-Benzyl-2-carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(2-methylpyridin-3-ylmethyl)-1H-imidazole 178980-27-3 C21H22Cl2N4O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(2-methylpyridin-3-ylmethyl)-1H-imidazole
    —— 1-Allyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-ylmethanol 178979-08-3 C16H18Cl2N2OS
    1-Allyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-ylmethanol
    —— 2-carbamoyloxymethyl-1-(2-carbamoyloxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazole 178980-47-7 C18H22Cl2N4O4S
    2-carbamoyloxymethyl-1-(2-carbamoyloxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazole
    —— 1-Allyl-2-carbamoyloxymethyl-4-isopropyl-5-(3-nitrophenylthio)-1H-imidazole 178979-38-9 C17H20N4O4S
    1-Allyl-2-carbamoyloxymethyl-4-isopropyl-5-(3-nitrophenylthio)-1H-imidazole
    —— 2-(2-(3-benzyloxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-1-yl)-ethanol 178980-56-8 C24H28Cl2N2O2S
    2-(2-(3-benzyloxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-1-yl)-ethanol
    —— 2-Diaminomethylenemethylaminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methylimidazole 178979-77-6 C16H21Cl2N5S
    2-Diaminomethylenemethylaminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methylimidazole
    —— 2-aminomethyl-5-(3-chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole 178981-67-4 C14H18ClN3S
    2-aminomethyl-5-(3-chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole
    —— 2-(5-Amino-3-methylsulfanyl-[1,2,4]triazol-1-yl)-ethanol 84827-82-7 C5H10N4OS
    2-(5-Amino-3-methylsulfanyl-[1,2,4]triazol-1-yl)-ethanol
    —— 2-(3-Amino-5-methylsulfanyl-[1,2,4]triazol-1-yl)-ethanol 84827-83-8 C5H10N4OS
    2-(3-Amino-5-methylsulfanyl-[1,2,4]triazol-1-yl)-ethanol
    —— 2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole 178979-43-6 C16H20ClN3O2S
    2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole
    —— 2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(2-(2-pyridyl)ethyl)-1H-imidazole 178980-22-8 C21H22Cl2N4O2S
    2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(2-(2-pyridyl)ethyl)-1H-imidazole
    —— [4-(3-Chlorophenyl)sulfanyl-5-isopropyl-1-methyl-imidazol-2-yl]methanol 178979-28-7 C14H17ClN2OS
    [4-(3-Chlorophenyl)sulfanyl-5-isopropyl-1-methyl-imidazol-2-yl]methanol
    —— 6-(4-Methoxyphenyl)sulfanylpyrido[3,2-d]pyrimidine-2,4-diamine 216167-07-6 C14H13N5OS
    6-(4-Methoxyphenyl)sulfanylpyrido[3,2-d]pyrimidine-2,4-diamine
    —— 2-((5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methylamino)ethanol 178979-70-9 C16H21Cl2N3OS
    2-((5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methylamino)ethanol
    —— 1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-1-ethyl-4-(1-methylethyl)- 178980-59-1 C17H22Cl2N2OS
    1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-1-ethyl-4-(1-methylethyl)-
    —— 2-Aminomethyl-5-(3-nitrophenylthio)-4-isopropyl-1-methyl-1H-imidazole 178979-58-3 C14H18N4O2S
    2-Aminomethyl-5-(3-nitrophenylthio)-4-isopropyl-1-methyl-1H-imidazole
    —— 2-(1-(2-Aminobenzyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl)ethanol 178980-37-5 C21H23Cl2N3OS
    2-(1-(2-Aminobenzyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl)ethanol
    —— 4-(benzylsulfanyl)-6-chloro-2-aminopyrimidine 478258-60-5 C11H10ClN3S
    4-(benzylsulfanyl)-6-chloro-2-aminopyrimidine
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-1-ethyl-4-isopropyl-1H-imidazole 178979-42-5 C16H19Cl2N3O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-1-ethyl-4-isopropyl-1H-imidazole
    —— [5-(3,5-Dichlorophenylthio)-1-dodecyl-4-isopropyl-1H-imidazol-2-yl]methanol 178979-07-2 C25H38Cl2N2OS
    [5-(3,5-Dichlorophenylthio)-1-dodecyl-4-isopropyl-1H-imidazol-2-yl]methanol
    —— 1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-((2-methyl-3-pyridinyl)methyl)- 178980-51-3 C20H21Cl2N3OS
    1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-((2-methyl-3-pyridinyl)methyl)-
    —— [5-(3,5-Dichlorophenylthio)-1-(4-aminobenzyl)-4-isopropyl-1H-imidazol-2-yl]methanol 178980-71-7 C20H21Cl2N3OS
    [5-(3,5-Dichlorophenylthio)-1-(4-aminobenzyl)-4-isopropyl-1H-imidazol-2-yl]methanol
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole 178979-88-9 C19H20Cl2N4S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole 178979-84-5 C20H20Cl2N4O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole
    —— 1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, carbamate (ester) 178980-45-5 C22H24Cl2N4O2S
    1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, carbamate (ester)
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole 178979-87-8 C19H20Cl2N4S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-2-ylmethyl)-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-2-methylamidinomethyl-1H-imidazole 178979-75-4 C16H20Cl2N4S
    5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-2-methylamidinomethyl-1H-imidazole
    —— 1-Benzyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-ylmethanol 178979-05-0 C20H20Cl2N2OS
    1-Benzyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-ylmethanol
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazole 178980-21-7 C24H22Cl2N4O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazole
    —— [2-(2-amino-6-chloropyrimidin-4-ylsulfanyl)ethyl]carbamic acid tert-butyl ester 1052648-77-7 C11H17ClN4O2S
    [2-(2-amino-6-chloropyrimidin-4-ylsulfanyl)ethyl]carbamic acid tert-butyl ester
    —— 6-sec-Butoxy-2-(3-chloro-phenylsulfanyl)-3H-pyrimidin-4-one 284681-69-2 C14H15ClN2O2S
    6-sec-Butoxy-2-(3-chloro-phenylsulfanyl)-3H-pyrimidin-4-one
    —— 2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(3-(2-pyridyl)propyl)-1H-imidazole 178980-23-9 C22H24Cl2N4O2S
    2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(3-(2-pyridyl)propyl)-1H-imidazole
    —— 2-Aminomethyl-5-(3-chlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole 178979-64-1 C15H20ClN3S
    2-Aminomethyl-5-(3-chlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole
    —— 1-Chlor-4,4-dimethyl-3-phenylthio-2-pentanon 53258-87-0 C13H17ClOS
    1-Chlor-4,4-dimethyl-3-phenylthio-2-pentanon
    —— 1-(p-N-acetylaminobenzyl)-5-(3,5-dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-1H-imidazole 178980-10-4 C22H23Cl2N3O2S
    1-(p-N-acetylaminobenzyl)-5-(3,5-dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-1H-imidazole
    —— {5-[(3,5-Dichlorophenyl)sulfanyl]-4-(1-methylethyl)-1-(thiophen-2-ylmethyl)-1h-imidazol-2-yl}methanol 178980-19-3 C18H18Cl2N2OS2
    {5-[(3,5-Dichlorophenyl)sulfanyl]-4-(1-methylethyl)-1-(thiophen-2-ylmethyl)-1h-imidazol-2-yl}methanol
    —— 3-Acetoxy-4,4-dimethyl-1-phenylthio-2-pentanon 65302-93-4 C15H20O3S
    3-Acetoxy-4,4-dimethyl-1-phenylthio-2-pentanon
    —— 1H-Imidazole-2-ethanol, 1-((4-aminophenyl)methyl)-5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)- 178980-33-1 C21H23Cl2N3OS
    1H-Imidazole-2-ethanol, 1-((4-aminophenyl)methyl)-5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-3-ylmethyl)-1H-imidazole 178979-86-7 C19H20Cl2N4S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-3-ylmethyl)-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazol-2-ylmethanol 178980-74-0 C23H21Cl2N3OS
    5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(quinolin-3-ylmethyl)-1H-imidazol-2-ylmethanol
    —— 5-(3,5-Dichlorophenylthio)-2-(-2-carbamoyloxyethyl)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole 178980-32-0 C21H22Cl2N4O2S
    5-(3,5-Dichlorophenylthio)-2-(-2-carbamoyloxyethyl)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazole
    —— 6-(sec-butoxy)-2-((4-chlorophenyl)thio)pyrimidin-4-amine 284681-50-1 C14H16ClN3OS
    6-(sec-butoxy)-2-((4-chlorophenyl)thio)pyrimidin-4-amine
    —— 2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1-n-propyl-1H-imidazole 178979-44-7 C17H22ClN3O2S
    2-Carbamoyloxymethyl-5-(3-chlorophenylthio)-4-isopropyl-1-n-propyl-1H-imidazole