摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词

有机硫化合物

有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在,在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特,在药物设计、合成化学以及材料制备方面扮演着重要角色。

1. 结构与分类

有机硫化合物可以按硫的连接方式分为饱和和不饱和类,如二硫化物、噻吩衍生物、砜等。常见的结构类型有:

  • 二硫化物:含-S-S-键的化合物。
  • 硫醚(Thiols):含有-R-S-H或-R-S-R 基团的化合物。
  • 磺酸酯(Sulfonates)与磺酸盐(Sulfonates):带有-SO3H基团的化合物,广泛应用于合成和制药领域。
  • 噻吩及其衍生物:具有环状结构的有机硫化物。
2. 生物学活性

许多有机硫化合物在生物学上有重要功能或应用潜力。例如:

  • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
  • 硫代葡萄糖苷(Glycosinolate)是十字花科植物中的一种天然存在物质,具有生物活性。
3. 合成方法

有机硫化合物可通过多种途径合成:

  • 亲核取代反应:使用含硫试剂与卤化物进行反应。
  • 自由基加成法:采用氧化剂引发自由基形成,通过烯烃与H2S、R-S-H等反应制备。
  • 金属催化转化:利用钯、铜等催化剂促进特定硫化过程。
4. 应用领域

有机硫化合物的应用广泛:

  • 医药领域:用于开发抗菌剂、抗病毒药物及抗癌药物等。
  • 农学研究:某些有机硫化合物作为生物农药的有效成分,能够抑制病害的发生。
  • 材料科学与技术:在导电聚合物和塑料添加剂中有重要应用。
5. 环境与安全性

尽管有机硫化合物具有许多潜在益处,但其生产和使用也可能对环境造成影响。因此,在设计和合成这些化合物时需要考虑可持续性和环保性因素。

以上是对有机硫化合物的简单介绍,包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

中文名称 英文名称 CAS号 化学式 结构式图片
—— 10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazin-4-amine, 7-chloro- 63931-16-8 C9H6ClN5S
10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazin-4-amine, 7-chloro-
—— (2-Chlorethyl)-heptyl-sulfoxid 24475-73-8 C9H19ClOS
(2-Chlorethyl)-heptyl-sulfoxid
—— (1,2-Dichloro-octylsulfanyl)-benzene 98750-72-2 C14H20Cl2S
(1,2-Dichloro-octylsulfanyl)-benzene
—— 2-[2-[3-[2,3-Bis[2-(2-sulfanylethylsulfanyl)ethylsulfanyl]propylsulfanyl]-2-[2-(2-sulfanylethylsulfanyl)ethylsulfanyl]propyl]sulfanylethylsulfanyl]ethanethiol 612849-13-5 C22H46S13
2-[2-[3-[2,3-Bis[2-(2-sulfanylethylsulfanyl)ethylsulfanyl]propylsulfanyl]-2-[2-(2-sulfanylethylsulfanyl)ethylsulfanyl]propyl]sulfanylethylsulfanyl]ethanethiol
—— 3-p-tert-Butylphenylthio-4-tert-butylpyridin 28856-85-1 C19H25NS
3-p-tert-Butylphenylthio-4-tert-butylpyridin
—— 2,5-dimethyl-2,3-dihydrobenzo[b]thiophene 14422-07-2 C10H12S
2,5-dimethyl-2,3-dihydrobenzo[b]thiophene
—— 1-(1,1-Diallyl-but-3-enyl)-4-methylsulfanyl-benzene 289699-82-7 C17H22S
1-(1,1-Diallyl-but-3-enyl)-4-methylsulfanyl-benzene
—— 5-methoxycarbonyl-6-hydroxy-pyrrolo<1,2-a><3,1>benzothiazepine 87574-07-0 C14H11NO3S
5-methoxycarbonyl-6-hydroxy-pyrrolo<1,2-a><3,1>benzothiazepine
—— (2R)-1-[2-[[(2S,6R)-6-[2-[tert-butyl(dimethyl)silyl]oxyethyl]oxan-2-yl]methyl]-1,3-dithian-2-yl]-3-[(2R,3S,6R,8R,9S)-2-[[tert-butyl(diphenyl)silyl]oxymethyl]-3-methoxy-9-methyl-1,7-dioxaspiro[5.5]undec-10-en-8-yl]propan-2-ol 950190-90-6 C49H78O7S2Si2
(2R)-1-[2-[[(2S,6R)-6-[2-[tert-butyl(dimethyl)silyl]oxyethyl]oxan-2-yl]methyl]-1,3-dithian-2-yl]-3-[(2R,3S,6R,8R,9S)-2-[[tert-butyl(diphenyl)silyl]oxymethyl]-3-methoxy-9-methyl-1,7-dioxaspiro[5.5]undec-10-en-8-yl]propan-2-ol
—— rac-1-(2-phenyl-1,3-dithian-2-yl)-2-(tert-butylsulfonamido)-5-hexene 1130687-81-8 C20H31NO2S3
rac-1-(2-phenyl-1,3-dithian-2-yl)-2-(tert-butylsulfonamido)-5-hexene
—— 5-phenyl-6-oxopyrrolo<1,2-a><3,1>benzothiazepine 87574-09-2 C18H13NOS
5-phenyl-6-oxopyrrolo<1,2-a><3,1>benzothiazepine
—— (2S)-2-[(1S)-1-(2-phenyl-1,3-dithian-2-yl)propyl]oxirane 1178869-67-4 C15H20OS2
(2S)-2-[(1S)-1-(2-phenyl-1,3-dithian-2-yl)propyl]oxirane
—— 2-[(2R,6S)-6-[[(4R,6S)-6-[[(2R,3S,6R,8R,9S)-2-[(R)-[2-[(2S)-but-3-en-2-yl]-1,3-dithian-2-yl]-hydroxymethyl]-3-methoxy-9-methyl-1,7-dioxaspiro[5.5]undec-10-en-8-yl]methyl]-2,2-dimethyl-1,3-dioxan-4-yl]methyl]oxan-2-yl]ethyl 2,2-dimethylpropanoate 950190-95-1 C40H66O9S2
2-[(2R,6S)-6-[[(4R,6S)-6-[[(2R,3S,6R,8R,9S)-2-[(R)-[2-[(2S)-but-3-en-2-yl]-1,3-dithian-2-yl]-hydroxymethyl]-3-methoxy-9-methyl-1,7-dioxaspiro[5.5]undec-10-en-8-yl]methyl]-2,2-dimethyl-1,3-dioxan-4-yl]methyl]oxan-2-yl]ethyl 2,2-dimethylpropanoate
—— (2R,3R)-3-[tert-butyl(dimethyl)silyl]oxy-1-[2-[(2R)-2-[tert-butyl(dimethyl)silyl]oxy-3-[(4R,6R)-2,2-dimethyl-6-tridecyl-1,3-dioxan-4-yl]propyl]-1,3-dithian-2-yl]pent-4-en-2-ol 1085711-09-6 C43H86O5S2Si2
(2R,3R)-3-[tert-butyl(dimethyl)silyl]oxy-1-[2-[(2R)-2-[tert-butyl(dimethyl)silyl]oxy-3-[(4R,6R)-2,2-dimethyl-6-tridecyl-1,3-dioxan-4-yl]propyl]-1,3-dithian-2-yl]pent-4-en-2-ol
—— 2-[(2R,6S)-6-[[(4R,6S)-6-[[(2R,3S,6R,8R,9S)-2-[(S)-[2-[(2S)-but-3-en-2-yl]-1,3-dithian-2-yl]-hydroxymethyl]-3-methoxy-9-methyl-1,7-dioxaspiro[5.5]undec-10-en-8-yl]methyl]-2,2-dimethyl-1,3-dioxan-4-yl]methyl]oxan-2-yl]ethyl 2,2-dimethylpropanoate 950190-94-0 C40H66O9S2
2-[(2R,6S)-6-[[(4R,6S)-6-[[(2R,3S,6R,8R,9S)-2-[(S)-[2-[(2S)-but-3-en-2-yl]-1,3-dithian-2-yl]-hydroxymethyl]-3-methoxy-9-methyl-1,7-dioxaspiro[5.5]undec-10-en-8-yl]methyl]-2,2-dimethyl-1,3-dioxan-4-yl]methyl]oxan-2-yl]ethyl 2,2-dimethylpropanoate
—— 2,4,7-Trichlor-1,3,6-triazaphenothiazin 63931-19-1 C9H3Cl3N4S
2,4,7-Trichlor-1,3,6-triazaphenothiazin
—— (R)-tert-butyl(1-(2-ethyl-1,3-dithian-2-yl)pent-4-en-2-yloxy)dimethylsilane 1221821-50-6 C17H34OS2Si
(R)-tert-butyl(1-(2-ethyl-1,3-dithian-2-yl)pent-4-en-2-yloxy)dimethylsilane
—— tert-butyl-[(2R,3R)-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-[(4S)-4-[tert-butyl(dimethyl)silyl]oxy-5-(1,3-dithian-2-yl)pentyl]-1,3-dithian-2-yl]-2-ethylbutoxy]-diphenylsilane 1178869-99-2 C47H82O3S4Si3
tert-butyl-[(2R,3R)-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-[(4S)-4-[tert-butyl(dimethyl)silyl]oxy-5-(1,3-dithian-2-yl)pentyl]-1,3-dithian-2-yl]-2-ethylbutoxy]-diphenylsilane
—— tert-butyl-[(2R,3R)-3-[tert-butyl(dimethyl)silyl]oxy-2-ethyl-4-[2-[3-[(2S)-oxiran-2-yl]propyl]-1,3-dithian-2-yl]butoxy]-diphenylsilane 1178869-82-3 C37H60O3S2Si2
tert-butyl-[(2R,3R)-3-[tert-butyl(dimethyl)silyl]oxy-2-ethyl-4-[2-[3-[(2S)-oxiran-2-yl]propyl]-1,3-dithian-2-yl]butoxy]-diphenylsilane
—— (2S)-2-[3-[2-[(2R,3S)-2-(methoxymethoxy)-3-(2-phenyl-1,3-dithian-2-yl)pentyl]-1,3-dithian-2-yl]propyl]oxirane 1178869-79-8 C26H40O3S4
(2S)-2-[3-[2-[(2R,3S)-2-(methoxymethoxy)-3-(2-phenyl-1,3-dithian-2-yl)pentyl]-1,3-dithian-2-yl]propyl]oxirane
—— (2S,4S)-1-{2-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propyl]-[1,3]dithian-2-yl}-6-(tert-butyl-diphenyl-silanyloxy)-4-triethylsilanyloxy-hexan-2-ol 625856-01-1 C47H82O6S2Si3
(2S,4S)-1-{2-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propyl]-[1,3]dithian-2-yl}-6-(tert-butyl-diphenyl-silanyloxy)-4-triethylsilanyloxy-hexan-2-ol
—— (2S)-1-[2-[tert-butyl(dimethyl)silyl]-1,3-dithian-2-yl]-5-[2-[(2R,3S)-2-[tert-butyl(dimethyl)silyl]oxy-3-(2-phenyl-1,3-dithian-2-yl)pentyl]-1,3-dithian-2-yl]pentan-2-ol 1178869-78-7 C40H72O2S6Si2
(2S)-1-[2-[tert-butyl(dimethyl)silyl]-1,3-dithian-2-yl]-5-[2-[(2R,3S)-2-[tert-butyl(dimethyl)silyl]oxy-3-(2-phenyl-1,3-dithian-2-yl)pentyl]-1,3-dithian-2-yl]pentan-2-ol
—— (1R,3S)-[3-(tert-butyldimethylsilanyloxy)-6,10-dithiaspiro[4,5]dec-1-yl]-methanol 870294-78-3 C15H30O2S2Si
(1R,3S)-[3-(tert-butyldimethylsilanyloxy)-6,10-dithiaspiro[4,5]dec-1-yl]-methanol
—— (+)(S)-3-Methyl-pentanthiol-(1) 22299-67-8 C6H14S
(+)(S)-3-Methyl-pentanthiol-(1)
—— 3-(4-Methylphenyl)sulfanyl-7-phenyl-3-phenylselanylspiro[3.5]nonane 1160784-75-7 C28H30SSe
3-(4-Methylphenyl)sulfanyl-7-phenyl-3-phenylselanylspiro[3.5]nonane
—— thiovaleraldehyde 7358-38-5 C5H10S
thiovaleraldehyde
—— 7-Chlor-2,4-diamino-1,3,6-triazaphenothiazin 42362-21-0 C9H7ClN6S
7-Chlor-2,4-diamino-1,3,6-triazaphenothiazin
—— 2-(3',5'-di-tert-butyl-2'-hydroxyphenyl)-5-(phenylthio)benzotriazole 145233-43-8 C26H29N3OS
2-(3',5'-di-tert-butyl-2'-hydroxyphenyl)-5-(phenylthio)benzotriazole
—— 4-thia-2,3-dimethyl-1,6-heptadiene 111948-33-5 C8H14S
4-thia-2,3-dimethyl-1,6-heptadiene
—— 5-isopropyl-1-hydroxyethoxymethyl-6-(phenylthio)uracil 137897-91-7 C16H20N2O4S
5-isopropyl-1-hydroxyethoxymethyl-6-(phenylthio)uracil
—— Trimethyl-[2-(3-phenylsulfanyl-propyl)-[1,3]dithian-2-yl]-silane 215182-49-3 C16H26S3Si
Trimethyl-[2-(3-phenylsulfanyl-propyl)-[1,3]dithian-2-yl]-silane
—— 1-ethoxymethyl-2-phenylthio-5-(2-pyridinyl)imidazole 120671-11-6 C17H17N3OS
1-ethoxymethyl-2-phenylthio-5-(2-pyridinyl)imidazole
—— 3-(1-Adamantanthio)-pyridin 54476-12-9 C15H19NS
3-(1-Adamantanthio)-pyridin
—— 2-Butin-1,4-diyl-bis(aethylxanthat) 22543-16-4 C10H14O2S4
2-Butin-1,4-diyl-bis(aethylxanthat)
—— 4-(3'-Methylthio)phenylbutyric acid 213607-85-3 C11H14O2S
4-(3'-Methylthio)phenylbutyric acid
—— 4-(2'-Bromo-5'-methylthio)phenylbutyric acid 213607-86-4 C11H13BrO2S
4-(2'-Bromo-5'-methylthio)phenylbutyric acid
—— 2-({2-[(tert-butoxycarbonyl)amino]phenyl}thio)acetic acid 574751-77-2 C13H17NO4S
2-({2-[(tert-butoxycarbonyl)amino]phenyl}thio)acetic acid
—— 2-<2-Chlor-phenylthio>-aethanol 13290-15-8 C8H9ClOS
2-<2-Chlor-phenylthio>-aethanol
—— Dichloro-bis-(dichloro-methanesulfonyl)-methane 120423-09-8 C3H2Cl6O4S2
Dichloro-bis-(dichloro-methanesulfonyl)-methane
—— 1,4-Bis-butylsulfonyl-butan 34756-60-0 C12H26O4S2
1,4-Bis-butylsulfonyl-butan
—— 5-amino-3-methyl-7-methylthiopyrimido<4,5-b><1,4>oxazin-2-one 138612-38-1 C8H8N4O2S
5-amino-3-methyl-7-methylthiopyrimido<4,5-b><1,4>oxazin-2-one
—— (S)-1-Phenyl-3-phenylsulfanylpropanol 223113-76-6 C15H16OS
(S)-1-Phenyl-3-phenylsulfanylpropanol
—— 3-(1-Methyl-1-propyl-butyl)-6-methylsulfanyl-[1,2,4,5]tetrazine 159801-93-1 C11H20N4S
3-(1-Methyl-1-propyl-butyl)-6-methylsulfanyl-[1,2,4,5]tetrazine
—— (1-(3-bromophenyl)but-3-enyl)(phenyl)sulfane 1382802-09-6 C16H15BrS
(1-(3-bromophenyl)but-3-enyl)(phenyl)sulfane
—— 2-methyl-2-(1-methylvinyl)-1,3-dithiane 64087-41-8 C8H14S2
2-methyl-2-(1-methylvinyl)-1,3-dithiane
—— (1-(2-bromophenyl)but-3-enyl)(phenyl)sulfane 1382802-08-5 C16H15BrS
(1-(2-bromophenyl)but-3-enyl)(phenyl)sulfane
—— trimethyl-[(2R)-1-[2-[[(2R)-oxiran-2-yl]methyl]-1,3-dithian-2-yl]pentadecan-2-yl]oxysilane 1085711-04-1 C25H50O2S2Si
trimethyl-[(2R)-1-[2-[[(2R)-oxiran-2-yl]methyl]-1,3-dithian-2-yl]pentadecan-2-yl]oxysilane
—— 1-phenylthio-2-trifluoroacetoxyoctane 80437-03-2 C16H21F3O2S
1-phenylthio-2-trifluoroacetoxyoctane
—— 8-(2,6-difluorobenzyl)-3-hydroxymethyl-7-methyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridin-5-one 1313425-88-5 C16H15F2NO2S
8-(2,6-difluorobenzyl)-3-hydroxymethyl-7-methyl-2,3-dihydro-5H-thiazolo[3,2-a]pyridin-5-one
—— 2-{6-[(2-{[(tert-butoxycarbonyl)amino]methyl}phenyl)thio][1,2,4]triazolo[4,3-a]pyridin-3-yl}phenyl tert-butyl carbonate 1344738-21-1 C29H32N4O5S
2-{6-[(2-{[(tert-butoxycarbonyl)amino]methyl}phenyl)thio][1,2,4]triazolo[4,3-a]pyridin-3-yl}phenyl tert-butyl carbonate