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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 5-(3,5-Dimethyl-benzyl)-6-ethyl-3-methoxy-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one 199852-21-6 C18H22N2O2S
    5-(3,5-Dimethyl-benzyl)-6-ethyl-3-methoxy-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one
    —— 5-(3,5-dichlorophenylthio)-2-hydroxymethyl-1-(2-hydroxy-2-methylpropyl)-4-isopropyl-1H-imidazole 178980-48-8 C17H22Cl2N2O2S
    5-(3,5-dichlorophenylthio)-2-hydroxymethyl-1-(2-hydroxy-2-methylpropyl)-4-isopropyl-1H-imidazole
    —— 2-Carbamoyloxymethyl-4-(3-chlorophenylthio)-5-isopropyl-1-methylimidazole 178979-49-2 C15H18ClN3O2S
    2-Carbamoyloxymethyl-4-(3-chlorophenylthio)-5-isopropyl-1-methylimidazole
    —— 2-[(2-Methylphenyl)methylsulfanyl]pyrimidine 646511-08-2 C12H12N2S
    2-[(2-Methylphenyl)methylsulfanyl]pyrimidine
    —— 5-(3,5-Dimethyl-benzyl)-3-ethoxy-6-ethyl-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one 199852-23-8 C19H24N2O2S
    5-(3,5-Dimethyl-benzyl)-3-ethoxy-6-ethyl-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazole 178979-67-4 C15H16Cl2F3N3S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazole
    —— 2,3-Bis(sulfanyl)butane-1,4-diol 64131-50-6 C4H10O2S2
    2,3-Bis(sulfanyl)butane-1,4-diol
    —— 6,8-bis(phenylthio)benzocycloheptene-1,4,7-trione 138147-83-8 C23H14O3S2
    6,8-bis(phenylthio)benzocycloheptene-1,4,7-trione
    —— 5-(3-Chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-ylmethanol 178979-02-7 C14H17ClN2OS
    5-(3-Chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-ylmethanol
    —— 2-[2-carbamoyloxymethyl-5-(3-chlorophenylthio)-1-methyl-1H-imidazol-4-yl]propiononitrile 178979-91-4 C15H15ClN4O2S
    2-[2-carbamoyloxymethyl-5-(3-chlorophenylthio)-1-methyl-1H-imidazol-4-yl]propiononitrile
    —— N-Butyl-N'-(t-pentyl)-thioharnstoff 14294-19-0 C10H22N2S
    N-Butyl-N'-(t-pentyl)-thioharnstoff
    —— 5-(3,5-Difluorophenylthio)-4-isopropyl-1-methyl-2-ureidomethyl-1H-imidazole 178979-81-2 C15H18F2N4OS
    5-(3,5-Difluorophenylthio)-4-isopropyl-1-methyl-2-ureidomethyl-1H-imidazole
    —— 6-phenylthiobenzocycloheptene-1,4,7-trione 138168-40-8 C17H10O3S
    6-phenylthiobenzocycloheptene-1,4,7-trione
    —— 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazol-2-ylmethanol 178979-23-2 C15H15Cl2F3N2OS
    5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazol-2-ylmethanol
    —— N-Methyl-N'-(t-pentyl)-thioharnstoff 14294-18-9 C7H16N2S
    N-Methyl-N'-(t-pentyl)-thioharnstoff
    —— 2-Carbamoyloxymethyl-5-(3,5-difluorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole 178979-48-1 C16H19F2N3O2S
    2-Carbamoyloxymethyl-5-(3,5-difluorophenylthio)-1-ethyl-4-isopropyl-1H-imidazole
    —— 5-(3,5-Dimethyl-benzyl)-6-ethyl-3-(2-hydroxy-ethoxy)-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one 199852-24-9 C19H24N2O3S
    5-(3,5-Dimethyl-benzyl)-6-ethyl-3-(2-hydroxy-ethoxy)-2,3-dihydro-thiazolo[3,2-a]pyrimidin-7-one
    —— 5-(3,5-Dichlorophenylthio)-2-(3-carbamoyloxypropyl)-4-isopropyl-1-methyl-1H-imidazole 178980-43-3 C17H21Cl2N3O2S
    5-(3,5-Dichlorophenylthio)-2-(3-carbamoyloxypropyl)-4-isopropyl-1-methyl-1H-imidazole
    —— 1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-1-methyl-4-(1-methylethyl)- 178980-60-4 C16H20Cl2N2OS
    1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-1-methyl-4-(1-methylethyl)-
    —— 4-Pyrimidinamine, 2-(butylthio)-6-(phenylthio)- 284681-95-4 C14H17N3S2
    4-Pyrimidinamine, 2-(butylthio)-6-(phenylthio)-
    —— 5-(3,5-Difluorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-ylmethanol 178979-26-5 C15H18F2N2OS
    5-(3,5-Difluorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-ylmethanol
    —— N-Cyclohexyl-N'-(tert-pentyl)-thioharnstoff 14294-21-4 C12H24N2S
    N-Cyclohexyl-N'-(tert-pentyl)-thioharnstoff
    —— 4-[(2-methylbenzyl)thio]pyridine 646511-29-7 C13H13NS
    4-[(2-methylbenzyl)thio]pyridine
    —— 3-Methylthio-5-(2,3-difluorophenyl)-1,2,4-thiadiazole 476315-88-5 C9H6F2N2S2
    3-Methylthio-5-(2,3-difluorophenyl)-1,2,4-thiadiazole
    —— (4-Ethyl-5-furan-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetic acid ethyl ester 439899-35-1 C12H15N3O3S
    (4-Ethyl-5-furan-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetic acid ethyl ester
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-1,4-diisopropylimidazole 178979-63-0 C16H21Cl2N3S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-1,4-diisopropylimidazole
    —— 1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)- 178980-58-0 C21H23Cl2N3OS
    1H-Imidazole-2-propanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)-
    —— 4(1H)-Pyrimidinone, 2-((4-chlorophenyl)thio)-6-(1-methylpropoxy)- 284681-70-5 C14H15ClN2O2S
    4(1H)-Pyrimidinone, 2-((4-chlorophenyl)thio)-6-(1-methylpropoxy)-
    —— 4-[(3-methylbenzyl)thio]pyridine 646511-31-1 C13H13NS
    4-[(3-methylbenzyl)thio]pyridine
    —— 5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-ylmethyl acetate 178979-30-1 C16H18Cl2N2O2S
    5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-ylmethyl acetate
    —— 2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-1-(1,2-dihydro-2-oxopyridin-3-ylmethyl)-4-isopropyl-1H-imidazole 178980-25-1 C20H20Cl2N4O3S
    2-carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-1-(1,2-dihydro-2-oxopyridin-3-ylmethyl)-4-isopropyl-1H-imidazole
    —— [1-Benzyl-5-(3-chlorophenylthio)-4-isopropyl-1H-imidazol-2-yl]methanol 178979-09-4 C20H21ClN2OS
    [1-Benzyl-5-(3-chlorophenylthio)-4-isopropyl-1H-imidazol-2-yl]methanol
    —— 1-(5-(3,5-Dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-1H-imidazol-1-yl)-2-propanone 178979-21-0 C16H18Cl2N2O2S
    1-(5-(3,5-Dichlorophenylthio)-2-hydroxymethyl-4-isopropyl-1H-imidazol-1-yl)-2-propanone
    —— 1,2-dimethyl-5-(3,5-dimethylphenylthio)-4-ethylimidazole 178978-94-4 C15H20N2S
    1,2-dimethyl-5-(3,5-dimethylphenylthio)-4-ethylimidazole
    —— 2-[(2,5-dimethylphenyl)thio]pyrimidine 646511-21-9 C12H12N2S
    2-[(2,5-dimethylphenyl)thio]pyrimidine
    —— 2-Aminomethyl-1-benzyl-5-(3,5-dichlorophenylthio)-4-isopropylimidazole 178979-61-8 C20H21Cl2N3S
    2-Aminomethyl-1-benzyl-5-(3,5-dichlorophenylthio)-4-isopropylimidazole
    —— Carbamic acid 5-(3,5-dichlorophenylsulfanyl)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazol-2-ylmethyl ester 178979-45-8 C16H16Cl2F3N3O2S
    Carbamic acid 5-(3,5-dichlorophenylsulfanyl)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazol-2-ylmethyl ester
    —— 2-[5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl]acetamide 178980-29-5 C15H17Cl2N3OS
    2-[5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl]acetamide
    —— 2-Aminomethyl-5-(3,5-dichlorophenylthio)-1-fluoromethyl-4-isopropylimidazole 178979-68-5 C14H16Cl2FN3S
    2-Aminomethyl-5-(3,5-dichlorophenylthio)-1-fluoromethyl-4-isopropylimidazole
    —— 1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-((4-nitrophenyl)methyl)- 178980-49-9 C20H19Cl2N3O3S
    1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-((4-nitrophenyl)methyl)-
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-1-fluoromethyl-4-isopropyl-1H-imidazole 178979-46-9 C15H16Cl2FN3O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-1-fluoromethyl-4-isopropyl-1H-imidazole
    —— 1H-Imidazole-1-ethanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-2-((phenylmethoxy)methyl)- 178980-53-5 C22H24Cl2N2O2S
    1H-Imidazole-1-ethanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-2-((phenylmethoxy)methyl)-
    —— {5-[(3,5-Dichlorophenyl)sulfanyl]-4-(1-methylethyl)-1-(thiophen-3-ylmethyl)-1h-imidazol-2-yl}methanol 178980-20-6 C18H18Cl2N2OS2
    {5-[(3,5-Dichlorophenyl)sulfanyl]-4-(1-methylethyl)-1-(thiophen-3-ylmethyl)-1h-imidazol-2-yl}methanol
    —— 2-Carbamoyloxymethyl-4-isopropyl-5-(3-nitrophenylthio)-1-n-propyl-1H-imidazole 178979-40-3 C17H22N4O4S
    2-Carbamoyloxymethyl-4-isopropyl-5-(3-nitrophenylthio)-1-n-propyl-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-2-(2-carbamoyloxyethoxy)-methyl-1-ethyl-4-isopropyl-1H-imidazole 178979-53-8 C18H23Cl2N3O3S
    5-(3,5-Dichlorophenylthio)-2-(2-carbamoyloxyethoxy)-methyl-1-ethyl-4-isopropyl-1H-imidazole
    —— 2-(2-Aminoethyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole 178979-73-2 C15H19Cl2N3S
    2-(2-Aminoethyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole
    —— 5-(3,5-Dichlorophenylthio)-2-(2-carbamoyloxyethyl)-4-isopropyl-1-methyl-1H-imidazole 178979-72-1 C16H19Cl2N3O2S
    5-(3,5-Dichlorophenylthio)-2-(2-carbamoyloxyethyl)-4-isopropyl-1-methyl-1H-imidazole
    —— 5-(3-Chlorophenylthio)-1,2-dimethyl-4-isopropylimidazole 178978-92-2 C14H17ClN2S
    5-(3-Chlorophenylthio)-1,2-dimethyl-4-isopropylimidazole
    —— 2-((4-(3,5-Dichlorophenylthio)-1-methyl-5-isopropyl-1H-imidazol-2-yl)methoxy)ethyl acetate 178979-54-9 C18H22Cl2N2O3S
    2-((4-(3,5-Dichlorophenylthio)-1-methyl-5-isopropyl-1H-imidazol-2-yl)methoxy)ethyl acetate
    —— 5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-n-propyl-1H-imidazole 178979-41-4 C17H21Cl2N3O2S
    5-(3,5-Dichlorophenylthio)-2-carbamoyloxymethyl-4-isopropyl-1-n-propyl-1H-imidazole