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    首页 分子通 按分子结构分类 有机化合物 有机硫化合物

    有机硫化合物

    有机硫化合物是指含有硫原子的有机化合物。这些化合物在自然界中广泛存在，在医药、农药和材料科学等领域有着重要的应用。有机硫化合物因其化学性质独特，在药物设计、合成化学以及材料制备方面扮演着重要角色。

    1. 结构与分类

    有机硫化合物可以按硫的连接方式分为饱和和不饱和类，如二硫化物、噻吩衍生物、砜等。常见的结构类型有：

    • 二硫化物：含-S-S-键的化合物。
    • 硫醚（Thiols）：含有-R-S-H或-R-S-R 基团的化合物。
    • 磺酸酯（Sulfonates）与磺酸盐（Sulfonates）：带有-SO3H基团的化合物，广泛应用于合成和制药领域。
    • 噻吩及其衍生物：具有环状结构的有机硫化物。
    2. 生物学活性

    许多有机硫化合物在生物学上有重要功能或应用潜力。例如：

    • 某些硫醚类药物被用于抗真菌、抗菌以及抗癌治疗。
    • 硫代葡萄糖苷（Glycosinolate）是十字花科植物中的一种天然存在物质，具有生物活性。
    3. 合成方法

    有机硫化合物可通过多种途径合成：

    • 亲核取代反应：使用含硫试剂与卤化物进行反应。
    • 自由基加成法：采用氧化剂引发自由基形成，通过烯烃与H2S、R-S-H等反应制备。
    • 金属催化转化：利用钯、铜等催化剂促进特定硫化过程。
    4. 应用领域

    有机硫化合物的应用广泛：

    • 医药领域：用于开发抗菌剂、抗病毒药物及抗癌药物等。
    • 农学研究：某些有机硫化合物作为生物农药的有效成分，能够抑制病害的发生。
    • 材料科学与技术：在导电聚合物和塑料添加剂中有重要应用。
    5. 环境与安全性

    尽管有机硫化合物具有许多潜在益处，但其生产和使用也可能对环境造成影响。因此，在设计和合成这些化合物时需要考虑可持续性和环保性因素。

    以上是对有机硫化合物的简单介绍，包括它们的结构、生物学活性、合成方法及其应用领域等基本信息。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— AE-641/30109032 127906-20-1 C15H17NO2S
    AE-641/30109032
    —— N,N-dimethyl-2-(2,4-dimethoxyphenylthio)benzylamine 127905-75-3 C17H21NO2S
    N,N-dimethyl-2-(2,4-dimethoxyphenylthio)benzylamine
    —— 4-(2-Methylaminomethyl-phenylsulfanyl)-benzene-1,3-diol 127906-35-8 C14H15NO2S
    4-(2-Methylaminomethyl-phenylsulfanyl)-benzene-1,3-diol
    —— 2-(2,4-Dimethoxy-phenylsulfanyl)-benzoyl chloride 127905-42-4 C15H13ClO3S
    2-(2,4-Dimethoxy-phenylsulfanyl)-benzoyl chloride
    —— [2-(2,4-Dimethoxy-phenylsulfanyl)-benzyl]-methyl-amine 127905-84-4 C16H19NO2S
    [2-(2,4-Dimethoxy-phenylsulfanyl)-benzyl]-methyl-amine
    —— ethoxy-ethyl-trisulfane 63833-15-8 C4H10OS3
    ethoxy-ethyl-trisulfane
    —— 1-Aethylsulfonyl-prop-1-in 13596-73-1 C5H8O2S
    1-Aethylsulfonyl-prop-1-in
    —— S,S'-Diethyl-1.2-dithiosquarat 52427-62-0 C8H10O2S2
    S,S'-Diethyl-1.2-dithiosquarat
    —— N,N-Diethyl-3-phenyl-3-(phenylthio)-1-propylamine oxalate 99507-50-3 C2H2O4*C19H25NS
    N,N-Diethyl-3-phenyl-3-(phenylthio)-1-propylamine oxalate
    —— 1-Aethylsulfinylpropin 25558-06-9 C5H8OS
    1-Aethylsulfinylpropin
    —— ethyl-isopropyl-tetrasulfane 63833-26-1 C5H12S4
    ethyl-isopropyl-tetrasulfane
    —— ethoxy-propyl-trisulfane 63833-16-9 C5H12OS3
    ethoxy-propyl-trisulfane
    —— ethoxy-isopropyl-trisulfane 63833-17-0 C5H12OS3
    ethoxy-isopropyl-trisulfane
    —— ethyl-propyl-tetrasulfane 63833-25-0 C5H12S4
    ethyl-propyl-tetrasulfane
    —— 2-amino-5-(pyridin-4-ylthio)thiazole 133691-53-9 C8H7N3S2
    2-amino-5-(pyridin-4-ylthio)thiazole
    —— 4-(4-chlorophenyl)-2-(methylsulfanyl)-1,3-thiazole-N-oxide 1184559-47-4 C10H8ClNOS2
    4-(4-chlorophenyl)-2-(methylsulfanyl)-1,3-thiazole-N-oxide
    —— cis{Pt(DMS)(DMSO)Cl4} 121605-64-9 C4H12Cl4OPtS2
    cis{Pt(DMS)(DMSO)Cl4}
    —— Pyrrolidine, 1-(3-phenyl-3-(phenylthio)propyl)-, oxalate 99507-49-0 C2H2O4*C19H23NS
    Pyrrolidine, 1-(3-phenyl-3-(phenylthio)propyl)-, oxalate
    —— methyl {2-[(3-hydroxyphenyl)sulfanyl]phenyl}acetate 122283-36-7 C15H14O3S
    methyl {2-[(3-hydroxyphenyl)sulfanyl]phenyl}acetate
    —— 2-(N-chloroacetyl)carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-1-(2-hydroxypropyl)-4-isopropyl-1H-imidazole 178982-49-5 C19H22Cl3N3O4S
    2-(N-chloroacetyl)carbamoyloxymethyl-5-(3,5-dichlorophenylthio)-1-(2-hydroxypropyl)-4-isopropyl-1H-imidazole
    —— methyl 2-[(3-hydroxyphenyl)sulfanyl]benzoate 252972-50-2 C14H12O3S
    methyl 2-[(3-hydroxyphenyl)sulfanyl]benzoate
    —— 2-(N-chloroacetyl)carbamoyloxymethyl-1-(2-(N-chloroacetyl)carbamoyloxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazole 178982-48-4 C22H24Cl4N4O6S
    2-(N-chloroacetyl)carbamoyloxymethyl-1-(2-(N-chloroacetyl)carbamoyloxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazole
    —— [1-(2-Hydroxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl]methanol 178979-22-1 C16H20Cl2N2O2S
    [1-(2-Hydroxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl]methanol
    —— methyl {4-[(4-hydroxyphenyl)sulfanyl]phenyl}acetate 252973-14-1 C15H14O3S
    methyl {4-[(4-hydroxyphenyl)sulfanyl]phenyl}acetate
    —— methyl {2-[(4-hydroxyphenyl)sulfanyl]phenyl}acetate 252973-06-1 C15H14O3S
    methyl {2-[(4-hydroxyphenyl)sulfanyl]phenyl}acetate
    —— hydron;5-(propan-2-ylamino)pentyl carbamimidothioate;dichloride —— C9H23Cl2N3S
    hydron;5-(propan-2-ylamino)pentyl carbamimidothioate;dichloride
    —— 3-(S-allyl-S-dioxomercapto)-1,2-epoxypropane 7566-04-3 C6H10O3S
    3-(S-allyl-S-dioxomercapto)-1,2-epoxypropane
    —— Pseudourea, 2-(2-((2-aminoethyl)amino)ethyl)-2-thio-, dihydrobromide 99548-66-0 C5H16Br2N4S
    Pseudourea, 2-(2-((2-aminoethyl)amino)ethyl)-2-thio-, dihydrobromide
    —— Pseudourea, 2,2'-((methylimino)diethylene)bis(2-thio-, trihydrobromide 99670-03-8 C7H20Br3N5S2
    Pseudourea, 2,2'-((methylimino)diethylene)bis(2-thio-, trihydrobromide
    —— 2-[1-Methylamino-meth-(E)-ylidene]-benzo[b]thiophen-3-one 128886-10-2 C10H9NOS
    2-[1-Methylamino-meth-(E)-ylidene]-benzo[b]thiophen-3-one
    —— 2-[1-p-Tolylamino-meth-(E)-ylidene]-benzo[b]thiophen-3-one 128886-11-3 C16H13NOS
    2-[1-p-Tolylamino-meth-(E)-ylidene]-benzo[b]thiophen-3-one
    —— 2-(N-phenylaminomethylene)-3(2H)-benzo<b>thiophene 74387-98-7 C15H11NOS
    2-(N-phenylaminomethylene)-3(2H)-benzo<b>thiophene
    —— Pseudourea, 2-(2-pyridyl)-2-thio-, dihydrobromide 99420-73-2 C6H9Br2N3S
    Pseudourea, 2-(2-pyridyl)-2-thio-, dihydrobromide
    —— 2-[2-carbamimidoylsulfanylethyl(ethyl)amino]ethyl carbamimidothioate;hydron;tribromide —— C8H22Br3N5S2
    2-[2-carbamimidoylsulfanylethyl(ethyl)amino]ethyl carbamimidothioate;hydron;tribromide
    —— 2-(2-(Dimethylamino)ethyl)-1,3,3-trimethyl-2-thiopseudourea dihydrobromide 99799-60-7 C8H21Br2N3S
    2-(2-(Dimethylamino)ethyl)-1,3,3-trimethyl-2-thiopseudourea dihydrobromide
    —— Methyl-4-tert.-butyl-1-thioallophanimidat 40943-28-0 C7H15N3OS
    Methyl-4-tert.-butyl-1-thioallophanimidat
    —— S-(3-chloropropyl) methylthiolcarbamate 51861-06-4 C5H10ClNOS
    S-(3-chloropropyl) methylthiolcarbamate
    —— hydron;N-methyl-N-(2-phenylsulfanylphenoxy)butan-1-amine;chloride —— C17H22ClNOS
    hydron;N-methyl-N-(2-phenylsulfanylphenoxy)butan-1-amine;chloride
    —— Methyl phenylthiomethylphosphinat 7351-36-2 C8H11O2PS
    Methyl phenylthiomethylphosphinat
    —— N-[2-(dimethylamino)ethyl]-1-phenylsulfanylcyclopentane-1-carboxamide;hydron;chloride —— C16H25ClN2OS
    N-[2-(dimethylamino)ethyl]-1-phenylsulfanylcyclopentane-1-carboxamide;hydron;chloride
    —— 3-Ethyl-2-methylthio-5H-cyclopenta<b>thiopyrane-4-thione 175396-43-7 C11H12S3
    3-Ethyl-2-methylthio-5H-cyclopenta<b>thiopyrane-4-thione
    —— 2,5-bis(1,3-benzodithiol-2-yl)-1-methylpyrrole 153850-73-8 C19H15NS4
    2,5-bis(1,3-benzodithiol-2-yl)-1-methylpyrrole
    —— 4-(diaminomethylideneamino)butyl carbamimidothioate;hydron;dibromide —— C6H17Br2N5S
    4-(diaminomethylideneamino)butyl carbamimidothioate;hydron;dibromide
    —— Cyclopentanecarboxamide, N,N-diethyl-1-(phenylthio)- 101329-89-9 C16H23NOS
    Cyclopentanecarboxamide, N,N-diethyl-1-(phenylthio)-
    —— Ethylamine, 2-(5-dimethylamino-1,3,4-thiadiazol-2-ylthio)-, dihydrochloride 101418-30-8 C6H14Cl2N4S2
    Ethylamine, 2-(5-dimethylamino-1,3,4-thiadiazol-2-ylthio)-, dihydrochloride
    —— 1-(Phenylthio)cyclohexanecarboxylic acid 2-morpholinoethyl ester oxalate 101329-97-9 C21H29NO7S
    1-(Phenylthio)cyclohexanecarboxylic acid 2-morpholinoethyl ester oxalate
    —— 2-(diethylamino)ethyl 1-(4-chlorophenyl)sulfanylcyclopentane-1-carboxylate;hydron;chloride —— C18H27Cl2NO2S
    2-(diethylamino)ethyl 1-(4-chlorophenyl)sulfanylcyclopentane-1-carboxylate;hydron;chloride
    —— Pyrrolidine, 1-((1-(phenylthio)cyclopentyl)carbonyl)- 101329-90-2 C16H21NOS
    Pyrrolidine, 1-((1-(phenylthio)cyclopentyl)carbonyl)-
    —— 2-(dimethylamino)ethyl 1-phenylsulfanylcyclohexane-1-carboxylate;hydron;chloride —— C17H26ClNO2S
    2-(dimethylamino)ethyl 1-phenylsulfanylcyclohexane-1-carboxylate;hydron;chloride
    —— 5-phenylthio-1,3-cyclopentadiene 122617-23-6 C11H10S
    5-phenylthio-1,3-cyclopentadiene